St.

Paul College of Ilocos Sur

(Member: St. Paul University System)
St. Paul Avenue, 2727 Bantay, Ilocos Sur

DEPARTMENT OF NURSING

Name: Charina Aubrey Riodil_ Section/Year Level: BSN-II Serviteurs Defenseurs De Saint Joseph_ Date: Feb. 26, 2020

Side Effects and Nursing Responsibilities

Name of Drug Classification Mechanism of Action Contraindications Indications Adverse Effects

Tramadol Opiate (narcotic) Tramadol is an opioid and Tramadol is It is considered a class There are two different
Hydrochloride analgesics like other opioids contraindicated in patients IV drug by the FDA and The most prevalent formulations of tramadol:
selectively bind to different who have had a has been since July side effects areextended-release and
opiate receptors in the hypersensitivity reaction 7th, 2014. Due to nausea, dizziness,immediate release. The
central nervous system. to any opioid. Patients possible abuse and constipation, extended-release and
The liver enzyme, under the age of twelve addiction potential, vomiting, immediate release both come
CYP2D6, converts should not use the limitations to its use somnolence, andin a capsule form. For the
tramadol to its active medication and patients should be for pain that headache. They tend extended-release, patients
metabolite M1, which has under the age of eighteen is refractive to other to occur during the should receive counseling on
a stronger affinity for the should not be given the pain medication, such initial treatment the drug; it should not be
mu receptor compared to medication if they have as non-opioid pain rather thanchewed, crushed, dissolved
the inactive form. had a history of medication. There are maintenance doses or spit before administration.
Tramadol does not bind to tonsillectomy or two forms of tramadol: of the drug. Administration of both
the mu receptor as much adenoidectomy. Because extended-release and Serious side effects formulations can be without
as morphine. tramadol can cause immediate release.  include respiratory regard to food, but the
respiratory depression, depression which administration of the
patients who have a may result in death. extended-release formula
history of severe should be at a consistent time
respiratory depression each day.

Drug Study 1
 St. Paul College of Ilocos Sur
(Member: St. Paul University System)
St. Paul Avenue, 2727 Bantay, Ilocos Sur

DEPARTMENT OF NURSING

Name: Charina Aubrey Riodil_ Section/Year Level: BSN-II Serviteurs Defenseurs De Saint Joseph_ Date: Feb. 26, 2020

Name of Classification Mechanism of Contraindications Indications Side effects Nursing Responsibilities

Drug Action and Adverse
effects
Generic Prokinetic The GI haemorrhage, mechanical Some products that may Drowsiness, dizz  Monitor BP carefully during IV
Name: meto agents. It works antiemetic action of  obstruction and perforation; interact with this drug iness, administration.
clopramide by speeding the metoclopramide is phaeochromocytoma; history include: antipsychotic tiredness, troubl  Monitor for extrapyramidal
(oral/injection movement of due to its of seizures. drugs (such e sleeping, reactions, and consult physician
) (MET oh food through the antagonist activity as aripiprazole, haloperid agitation, headac if they occur.
KLOE pra stomach and at D2 receptors in ol), atovaquone, dopami he,  Monitor diabetic patients,
mide) intestines. the chemoreceptor ne agonists (such and diarrhea ma arrange for alteration in insulin
dose or timing if diabetic control
Brand trigger zone in the as cabergoline, y occur. If any of
is compromised by alterations in
Names: Met central nervous pergolide, ropinirole), these effects
timing of food absorption.
ozolv ODT, system — fosfomycin, pramlintide, persist or  WARNING: Keep
Reglan this action prevents phenothiazines (such worsen, tell your diphenhydramine injection
nausea and as promethazine, prochlo doctor readily available in case
vomiting triggered rperazine), rivastigmine. or pharmacist pr extrapyramidal reactions occur
by most stimuli. Metoclopramide causes omptly. (50 mg IM).
Metoclopramide als food and medication to  WARNING: Have
o increases the move through phentolamine readily available in
tone of the lower your stomach more case of hypertensive crisis (most
esophageal quickly, which may affect likely to occur with undiagnosed
sphincter. the absorption of some pheochromocytoma).
drugs.

Name: Charina Aubrey Riodil_ Section/Year Level: BSN-II Serviteurs Defenseurs De Saint Joseph_ Date: Feb. 26, 2020

Drug Study 1
 St. Paul College of Ilocos Sur
(Member: St. Paul University System)
St. Paul Avenue, 2727 Bantay, Ilocos Sur

DEPARTMENT OF NURSING

Side Effects and Nursing Responsibilities

Name of Classification Mechanism of Action Contraindications Indications Adverse Effects
Drug

Ketorolac Anti-pyretic Anti-inflammatory and Contraindicated with Short-term management of CNS: headache, Renal impairment, impaired
NSAID analgesic activity; significant renal pain (up to 5 days) dizziness, somnolence, hearing, allergies, hepatic,
inhibits prostaglandins impairment, aspirin insomnia, fatigue, tinnitus,
ophthalmologic effects Skin color and lesions,
and leukotriene allergy, recent GI bleed orientation, reflexes
synthesis. or perforation. Use peripheral sensation, clotting
cautiously with times, CBC, adventitious
impaired hearing; sounds
allergies; hepatic
conditions Be aware that patient may be
at risk for CV events, GI
bleeding, renal toxicity,
monitor accordingly

Name: Charina Aubrey Riodil_ Section/Year Level: BSN-II Serviteurs Defenseurs De Saint Joseph_ Date: Feb. 26, 2020

Drug Study 1
 St. Paul College of Ilocos Sur
(Member: St. Paul University System)
St. Paul Avenue, 2727 Bantay, Ilocos Sur

DEPARTMENT OF NURSING

Side Effects and Nursing Responsibilities

Name of Classification Mechanism of Action Contraindications Indications Adverse Effects
Drug
Ranitidine Antiulcer drugs Ranitidine is a Ranitidine is
Hydrochloride competitive inhibitor of contraindicated in FDA-Approved Ranitidine  Central nervous  Assess patient for
system
histamine H2- patients who have Indications abdominal pain. Note
(CNS): Malaise, presence of blood in
receptors. The previously experienced  Benign gastric ulcer dizziness, emesis, stool, or
reversible inhibition of a hypersensitivity disease, short-term, somnolence,
H2-receptors in gastric reaction to ranitidine or gastric aspirate.
and maintenance insomnia, vertigo,
parietal cells results in any of the product mental confusion,  Instruct patient on
a reduction in both components. Small  Duodenal ulcer
agitation, and proper use of OTC
disease, short-term,
gastric acid volume case series and hallucinations. preparation, as
and maintenance
and concentration. analyses demonstrate indicated.
Ranitidine’s acid- conflicting results  Cardiovascular: Ta
 Erosive esophagitis
chycardia,
lowering effect is more regarding cross-  Remind patient to take
 Hypersecretory bradycardia,
pronounced for basal sensitivity among H2- once-daily prescription
conditions (e.g., asystole,
and nocturnal acid receptor antagonists; drug at bedtime for
Zollinger-Ellison, atrioventricular
secretion than it is for caution is advised. block, and best results.
systemic mastocytosis,
food-stimulated acid multiple endocrine premature
secretion.   Instruct patient to take
adenoma syndrome)   ventricular beats.
without regard to
meals because
absorption isn’t
affected by food.

 Urge patient to avoid

cigarette smoking
because this may
increase gastric acid
secretion and worsen
disease.

Drug Study 1
 St. Paul College of Ilocos Sur
(Member: St. Paul University System)
St. Paul Avenue, 2727 Bantay, Ilocos Sur

DEPARTMENT OF NURSING

 Advise patient to
report all adverse
reactions, especially
abdominal pain, blood
in stool or emesis,
coffee-ground emesis,
or black, tarry stools.

Name: Charina Aubrey Riodil_ Section/Year Level: BSN-II Serviteurs Defenseurs De Saint Joseph_ Date: Feb. 26, 2020

Name of Classification Mechanism of Contraindications Indications Side effects and Adverse Nursing
Drug Action effects Responsibilities

Drug Study 1
 St. Paul College of Ilocos Sur
(Member: St. Paul University System)
St. Paul Avenue, 2727 Bantay, Ilocos Sur

DEPARTMENT OF NURSING

Cefuroxime ( Cephalosporins, Cefuroxime, like the  Antimicrobial For the treatment of many >10%  Instruct patient to
Rx) 2nd Generation penicillins, is a beta- resistance, different types of bacterial Diarrhea (4-11%; depends on avoid alcohol
Brand and lactam antibiotic. By viral infection infections such as bronchitis, duration) while taking this
Other binding to specific  Cephalosporin sinusitis, tonsillitis, ear 1-10% drug and for 3
Names: penicillin-binding hypersensitivit infections, skin infections, Decreased hemoglobin or days after
Ceftin, proteins (PBPs) gonorrhea, and urinary tract hematocrit (10%) because severe
y, penicillin
Zinacef located inside the infections. Eosinophilia (7%) reactions often
hypersensitivit
Dosage: Nausea or vomiting (3-7%) occur.
bacterial cell wall, it y
500mg
inhibits the third and Vaginitis (<5%)  Instruct patient
Frequency:  Renal failure, Transient rise in hepatic may experience
last stage of renal
TID transaminases (2-4%) these side effects:
bacterial cell wall impairment Diaper rash (3%) Stomach upset or
synthesis. Cell lysis  Colitis, Increase in alkaline diarrhea.
is then mediated by diarrhea, GI phosphatase (2%)  Advice patient to
bacterial cell wall disease, Thrombophlebitis (2%) report severe
autolytic enzymes inflammatory Increase in lactate diarrhea, difficulty
such as autolysins; it bowel disease, dehydrogenase (1%) breathing,
is possible that pseudomembr <1% unusual tiredness
cefuroxime anous colitis, Anemia or fatigue, pain at
interferes with an ulcerative Cholestasis injection site.
autolysin inhibitor. colitis Colitis
Dyspnea
Epidermal necrolysis
Increase in blood urea
nitrogen (BUN) and
creatinine
Jaundice
Nephritis
Prolonged prothrombin time
(PT)/international normalized
ratio (INR)
Rash

Drug Study 1
 St. Paul College of Ilocos Sur
(Member: St. Paul University System)
St. Paul Avenue, 2727 Bantay, Ilocos Sur

DEPARTMENT OF NURSING

Stevens-Johnson syndrome
Stomach cramps
Transient neutropenia and
leukopenia
Urticaria

Name: Charina Aubrey Riodil_ Section/Year Level: BSN-II Serviteurs Defenseurs De Saint Joseph_ Date: Feb. 26, 2020

Side Effects and Nursing Responsibilities

Name of Classification Mechanism of Action Contraindications Indications Adverse Effects
Drug

Drug Study 1
 St. Paul College of Ilocos Sur
(Member: St. Paul University System)
St. Paul Avenue, 2727 Bantay, Ilocos Sur

DEPARTMENT OF NURSING

Omeprazole Antiulcer drugs Inhibits proton pump Contraindicated in  Symtomatic GERD CNS: asthenia, dizziness,  Tell patient to swallow
activity by binding to patients hypersensitive without esophageal headache tablets whole and not
hydrogen-potassium to drug or its lesions to open, crush or
GI: abdominal pain,
adenosine components and in  Erosive esophagitis chew them.
constipation, diarrhea,
triphosphatase, located patients receiving  Pathologic flatulence, nausea,  Give patient
at secretory surface of rilpivirine-containing hypersecretory vomiting, acid regurgitation instructions on how to
gastric parietal cells, to products. coditions (such as take oral suspension.
suppress gastric acid Zollinger-Ellison Muscoloskeletal: back pain
secretion Syndrome)  Instruct patient to take
Respiratory: cough, URI
 Duodenal ulcer (short drug at least 30 to 60
term treatment) Skin: rash minutes before meals.
 Short-term treatment of
 Teach patient to
active benign gastric
recognize and report
ulcer
signs and symptoms
 Frequent heartburn (2 of low magnesium
or more days a week) levels.

Name: Charina Aubrey Riodil_ Section/Year Level: BSN-II Serviteurs Defenseurs De Saint Joseph_ Date: Feb. 26, 2020

Side Effects and Nursing Responsibilities

Name of Classification Mechanism of Action Contraindications Indications Adverse Effects
Drug

Drug Study 1
 St. Paul College of Ilocos Sur
(Member: St. Paul University System)
St. Paul Avenue, 2727 Bantay, Ilocos Sur

DEPARTMENT OF NURSING

Cefazolin cephalosporin ant In vitro tests Contraindicated in Mainly used to treat bacterial

ibiotics demonstrate that the patients hypersensitive infections of the skin. It can CV: phlebitis,  Instruct patient to
bactericidal action of to drug or other also be used to treat thrombophlebitis with I.V, report any adverse
cephalosporins results cephalosporins. moderately severe bacterial injection reactions promptly.
from inhibition of cell infections involving the lung, GI: diarrhea,  Tell patient to report
wall synthesis. By bone, joint, stomach, blood, pseudomembranous discomfort at I.V
binding to specific heart valve, and urinary tract. colitis, anorexia, glossitis, injection site.
penicillin-binding It is clinically effective against dyspepsia, abdominal
proteins (PBPs) infections caused by cramps, anal pruritis, oral  Advise patient to notify
located inside the staphylococci and streptococci candidiasis prescriber if a rash
bacterial cell wall, it species of Gram positive develops or if signs
inhibits the third and bacteria. May be used for Hematologic: and symptoms of
last stage of bacterial surgical prophylaxis; if super infection, such
cell wall synthesis. Cell required metronidazole may as fever, chills, and
lysis is then mediated be added to cover B. fragilis. malaise, appear.
by bacterial cell wall
autolytic enzymes such
as autolysins.

Name: Charina Aubrey Riodil_ Section/Year Level: BSN-II Serviteurs Defenseurs De Saint Joseph_ Date: Feb. 26, 2020

Name of Drug Classification Mechanism of Contraindications Indications Side effects and Adverse effects Nursing
Action Responsibilities

Drug Study 1
 St. Paul College of Ilocos Sur
(Member: St. Paul University System)
St. Paul Avenue, 2727 Bantay, Ilocos Sur

DEPARTMENT OF NURSING

Generic  Iron Iron combines  Hypersensitivity Iron deficiency  Therapeutic doses - nausea,  Advice patient to
Name: ferrous Products with porphyrin  Hemochromatosis anemia, blood loss upper abdominal pain, take medicine as
sulfate (FER us  Drug and globin chains , hemolytic anemia related to pregnancy constipation or diarrhea prescribed.
SUL fate) Used in to form or GI bleeding  Iron overdose (1-2 g) can  Advice patient to
Brand Anemia hemoglobin, (NSAIDs), hookworm lead to circulatory collapse consult physician
Names: Feosol, (microcyt which is critical infestation, or excess
and death. Non-intentional if irregular
Fer Iron, Fer- ic) for oxygen coffee
iron overdose has been a heartbeat,
delivery from the
Gen-Sol, Fer-in- leading cause of fatal dyspnea, swelling
lungs to other
Sol, Fer-Iron, poisoning in children <6 of hands and feet
tissues.
Feratab, FeroSul, Iron deficiency years old. Keep out of reach and hypotension
Ferra-TD, Ferro- causes of children. occurs.
Bob, Lydia E. a microcytic  Iron overdose can be treated  Inform patient that
Pinkham, MyKidz anemia due to by gastric lavage with a angina attacks
Iron 10, Slow Fe the formation of phosphate solution may occur 30
Dosage: 1 Tablet small and deferoxamine (iron min, after the
Route: P.O erythrocytes with chelator). administration
Frequency: 2x a insufficient due to reflex
day hemoglobin. tachycardia

Name: Charina Aubrey Riodil_ Section/Year Level: BSN-II Serviteurs Defenseurs De Saint Joseph_ Date: Feb. 26, 2020

Side Effects and Nursing Responsibilities

Name of Classification Mechanism of Action Contraindications Indications Adverse Effects
Drug

Drug Study 1
 St. Paul College of Ilocos Sur
(Member: St. Paul University System)
St. Paul Avenue, 2727 Bantay, Ilocos Sur

DEPARTMENT OF NURSING

 Assess Vital Signs
Omeprazole Antiulcer drugs Inhibits proton pump Contraindicated in  Symtomatic GERD CNS: asthenia, dizziness,
activity by binding to patients hypersensitive without esophageal headache  Teach patient to
hydrogen-potassium to drug or its lesions recognize and report
GI: abdominal pain,
adenosine components and in  Erosive esophagitis signs and symptoms
constipation, diarrhea,
triphosphatase, located patients receiving  Pathologic of low magnesium
flatulence, nausea,
at secretory surface of rilpivirine-containing hypersecretory levels
vomiting, acid regurgitation
gastric parietal cells, to products. coditions (such as  Check for abdominal
suppress gastric acid Zollinger-Ellison Muscoloskeletal: back pain
Pain, emesis,
secretion Syndrome) Respiratory: cough, URI Diarrhea
 Duodenal ulcer (short or constipation.
term treatment) Skin: rash
 Short-term treatment of  Evaluate fluid and
active benign gastric intake
ulcer
 Watch for elevated
 Frequent heartburn (2
liver function test
or more days a week)
results
 

Name: Charina Aubrey Riodil_ Section/Year Level: BSN-II Serviteurs Defenseurs De Saint Joseph_ Date: Feb. 26, 2020

Drug Study 1
 St. Paul College of Ilocos Sur
(Member: St. Paul University System)
St. Paul Avenue, 2727 Bantay, Ilocos Sur

DEPARTMENT OF NURSING

Side Effects and Nursing Responsibilities

Name of Classification Mechanism of Action Contraindications Indications Adverse Effects
Drug
Celexocib Antirheumatic Exhibits anti-  Hypersensitivity Adjunctive treatment to CNS: dizziness, Before:
inflammatory, to drug, decrease the number drowsiness, headache,
analgesic, and of adenomatous colorectal insomnia, fatigue  Assess pt’s history
sulfonamides,
antipyretic action due polyps in familial adenomatous of allergic reaction to
or other
CV: Peripheral edema the drug
to inhibition of the NSAIDs polyposis
enzymeCOX-2 EENT: ophthalmic effects,  Monitor complete
 Severe hepatic
tinnitus, pharyngitis, blood count,
impairment
rhinitis, sinusitis electrolyte levels,
 History of creatinine clearance,
GI: nausea, diarrhea,
asthma or and occult fecal blood
constipation, abdominal
urticarial test and liver function
pain, dyspepsia,
test results every 6 to
 Advanced flatulence, drymouth, GI
12months
Renal disease bleeding
During:
 Late pregnancy GU: menorrhagia
 Instruct patient to take
 Breastfeeding Hematologic: Decreased
drug with food or milk.
hemoglobin or hematocrit
 Teach patient to avoid
aspirin and other
NSAIDs (such as
ibuprofen and
naproxen) during
therapy.
After:

 Advise patient to

Drug Study 1
 St. Paul College of Ilocos Sur
(Member: St. Paul University System)
St. Paul Avenue, 2727 Bantay, Ilocos Sur

DEPARTMENT OF NURSING

immediately report
bloody stools, blood in
vomit, or signs or
symptoms of liver
damage (nausea,
fatigue, lethargy,
pruritus, yellowing of
eyes or skin,
tenderness on upper
right side of abdomen,
or flu like symptoms).
 

Drug Study 1