I Q. 1---Q. 20 cnrry one mark each.

I
The characte ristic odour of011ion bulbs is attribute d to
Q. t . .
(A) quercetin glycosides (B) furostanol gtycosr.des .
(C) heterogeneous sulphated polysaccharides (D) alkyl or alkenyl drsulphrdes
Q.l. The chief constituent of the seeds of ｓｴｲｯｰｬｾ｡ｮｨｵｳ＠ graws .or wood of ａｾｯｨｭｲ･ｵ＠
schimpe ri belongin g to rhefamil yi4pocyn acea ts G-stroph anthm.
On hydrolys rs. rl gnes
(A) scillarenin (B) ｯｾ｢｡ｧ･ Ｎ ｭｮ＠
(C) cannogenin . (D) drosgemn
Q.3. The duration ofaction ofa sublingu alnilrog lycerm tablet rs
(A) 8 _ 1o hours (B) 4-8 ho.urs
(C) 10-30 minutes . (D) 3- S rmnutes .
Q.4. Identify the adrenerg ic receptor, whose ago11ists can be misused by sportsmenｦ｡ｲ ｾ＠
t!J!ects
(A) !XI
(C) 6,
Q.S. When the urinary pH becomes 8.0, slgnijica/ll increase in the excretio
n ofone ofthe drugs
takes place
(A) Mepyramine (B) Aspirin
(C) Morphine (D) Mecamylamine
Q.ti. Condensation of 6-Hydroxy-2,4,5-triamillopyrimidine
with 1,1,3-trichloro acetone and
N-(4-aminobeTIZQy/) glutamic acid at pH 4to 5. in the presence
ofsodium bisulphiJe gives
(A} Pteroyl g lutamic acid (B) Amethopterin
(C) Triamterene (D) Aciclovi r
Q.7. The comnro11 s/nJChlral fearure of iodoxamic acid, iotalamlc
acid, diatrizolc acid and
iocarmic acid is
(A) sulphonaphthalein (B) 2,4,6-tri-iodo benzoic acid
(C) tri-iodo triphenyl methano ic acid (D) tri-iodo diphenyl methanoic acid
Q. 8. Tra11ylcypromine, a p.yychoanalepti<; and antidepressant drug
is symlresi zedfrom

(A) o-CH 2CH2 CHs + ｎ ｾ ｎＧＭＯｃｏＲｈｾ＠

(B)o- CH=C H2 ·.+ ｎ ｾｎＧＭＯｃｏＲｈｳ＠
(C) 0 + ｎ ｾｎＧＭＯｃｏｈ Ｒ ｃｈ Ｒ ｃｈ Ｓ＠

(D) o-C H=CH2 + ｎ ｾ ｎ ｾｃ ｏｃｈ Ｒ ｃｳｈ＠

Q. 9. List of diseases and ailments which a drug ｭｾｹ＠ not ｰｲｾｯｴ＠ to prevent or cure or make
claims to prevent or cure under tire Drugs and Cosmeti cs Rule
1945 is given under
(A) Schedule J (B) sChedule K
(C) Schedule M (D) ｾｨ･､ｵｬ＠ P
Q. HI. Annatto consists pf the dried seed1 Bixa orelkma ,
constiJuerrt is
of L. Family ｊｌｾ｡ ｣･｡ ･Ｎ＠ The chief
(A) triterpene alcohol (B) crocin and crocetin
(C) capsanthin (D) catoteno id
Q. 11. 'Cresol wilh soap solutian ' Is a preparalion, in which soap
i.f incorpo rated to
(A) impart detergent property
(B) improve mutual miscibility of cresol ru1d water by reducing
critical solution
• temperature of cresol-water system
(C) sustain the germicidal action of cresol
(D) improve the stability of cresol
Q.12. Wlren stoichiometric amount of CaCl is added to an
2 enrulsio11 stabilize d with sodium-
alginate, ir will
(A) crack immedia telv
(B) change the nature from w/o to o/w
(C) change the nature from olw to w/o
(D) accloler:_ate the phenomenon of Ostwald ｾｩｰ･ｮｧＮ＠
Q. 13• .Chlorille ｯｲ Ｎ ｂｲｯｭｩｾ･＠ substitution in aromallC compcundsd
(A) enhance s fluorescence b th fl s, ce
(8 ) oes not c ange . e uore cen
(C) ueoches the fluorescence (D) removes the fluorescence
Q. 14. ｓｯｬｶｾｮｴ＠ programming, a/5o called gradient elution, involves
(A) c.hanging the column length ..
(B) ehangin g the mobile phase compositiOn
(C) using the mobil!l phase unchanged www.examrace.com
(D) successive injection of sample.
 Q; 15. Callbratio11 ofｴｨｾ Ｍ cell constant'ofa conducta11ce cell is carried out by using a solutiont!f
(A) 0.1 M N aCI . (B) 0.1 M CaCI2
(C) 0.1M KCI (D) 0.1M AICJ3
Q.l6. Hybridama technology is widely usedfor producing
(A) callus cultures · (B) organ cultures
(C) monoclonal antibodies (D) attenuated micro-organisms
Q.17. ·Gene therapy'ufers to the process of:
(A) identifying disease causing genes and activating them for therapeutic benefit.
(B) increasing the expression levels of the set of genes involved in a given disease in
affected cells through selective modulating agents. ·
(C) transfer of new genetic materia l to the cells of an individua l for therapeutic benefit.
(D) removal of the proteins corresponding to the disease causing genes from the cells of
the affected individual.
Q.l8. A teclmician is allempling to sterilize a plug ofcptfon in hernltlicaUy staled a>ndition in a
glas.s boule by autoc/oving. Which ofthe following statements Is correct?
(A) It should be sterilized at II S- 11SOC for 30 m inutes.
(B) It should be sterilized at 121 to 124° C for 15 minutes at IS lbs/sq. inch pressure.
( C) Sterilization cannot be achieved.
(D) It sbould be autoclaved at 126- 129° C with saturated steam for 10 minutes.
Q.19. Hypemricaemia is associated with the abnorMal metabolisn1of
(A) pyrimidine (B) purine
(C) riboflavin (D) thiamme
Q.lO. What is the concentration ofNaCI required to make 1% solution ofcocai11e HC I Isotonic
with 5/ood plasma? Freezing point of 1% w/v solUJion ofNaCI is ·0.576° C andfreezing
painl of I% wlv cocaine HCI is -0.09"C.
{A) 0.746o/o w/v (B) 0.9% w/v
!C) 0.5 w/v !p)037Jlw/v
1 Q. 21 to Q. 1s carry two marks each
Q.21. Arillode is
(A) warty out-growth from micropyle, e.g., castor
(B) succulent growth from hilum .covering the entire seeds, e.g.. nutmeg
{:C) Outgrowth originating front micropyle and COVering the SeedS, e.g. , CardamOIJ!
(D) enlarged funicle, e.g.• colchicum seed. .
Q. 2l. Cinnamon consists ofthe dried inner bark ofthe sh{)()fS ofcoppiced trees ofCinnamomum
zeylanicum Nees. The typical microscopic characTers ofthe bark are
(A) biseriate medullary rays. secretory cavities conrainit\g volatile oil and mucilage a nd
few starch grains in cortical parenchyma and calcium oxalate in parenchymatous cells .
·(B) 2-S layers of cork cells containing_ oil globules. Pt·esence ofschizogenous canal .- ﾷｾ＠
(C) medu llary rays multiseriate, the peridertll portion cork has both._!angentially and
radially elongated cells, stone cells present and no phloem tibres ·- ·
(D) ex-foliated cork, non-lignified with 2-4 1ayers ofphellogen. 15· 20 rowsofphelloderm.
Prominent va.sCular tissue. ·
·Q .23. ·All essential ingredie111 in the ge11eral preJXuation ofplant tissue cuiJure media is
(A) auxin or naphthalene acetic acid (B) sucrose or glucose
(C) gibberlin G 1 or g ibberlin G 2 . I . (D) pyridoxine HCI. •·
Q.24• .J'he drogs mefloquine, proguani/ qpd primaquine can be effectively used in diseases
produced by '
(/\) Mycoplasma (B) Dcrmatophytes
(C) Protozoa ./ (D) Spirdchaetes
· Q.25,- lde11tify the receptor which demonstrates the fastest onset ofrespo,se, when stimulated.
(A) Nuclear receptor,; (B) Ionotropic receptors
(C) G-protein coupled receptors (D) Insulin receptor
Q.26. One of the following drugs is converted to ｴｨｾ＠ corresponding d eoxy nucleotide, which
shows cytotoxicity
(A) Dactinomycin (B) Lonwsrine
(C) Vincristine (D) S·f luorouraci l
Q.27. The compounds 2·Methyl·3-phytyl-l, 4-naphthoqui'nolle and 2-methyi-3-al/·trans-
ｦ｡ｭ･Ｌｾｹｬｧｲｮ ｹｬｧ･ｲ｡ｮ Ｍ Ｑ Ｌ＠ 4-naphthoquinone are commo11ly known as
(A) Vitamin D 2 aud D3 (B) Vitamin A 1 and A2 /
(C) Vitamin K 1 and K2 (D) Vitamin.B 1' and B 2
Q.28. (Z)·5·Fiuoro· 2·methyl-l-{[P·(methyl-sulphi11y/) phenyl} methylerte}-IH indene-3-acet fc
acid, reaches peak blood levels withi11 2-4 hours and undergoes a complicated reversible
metabolism to become active_ Active metabolite has the group

ｾ＠ 0
(A) R"'ISI' R (B) 5II
R"' ' R
0
H
(C)R..-S' R (D)
.R
J, R
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 . he . of benzodiozepine derivatives can be prepared IYy
Q.29. An inrermedwte for .'he ｳｾｴ＠ srs hi 'de in the presence of zinc chloride a.< a
treating 4-chloro am/me wrth benzoy1 c orl . .
catalyst. Identify the intermediate

Cl

(A)

Cl
/

(0)

ｾ＠
4-NHCO OCH 3
(D) N

0
Q.31. In the preparation ofointments, macrogols are used as
(A) water soluble base (B) hydrocarbon base
(C) absorption base (D) oleogenous base
Q.32. An antioxidallt commonly med in the formulation ofa non-aqueous parenteral
preparation is
(A) thioglycollic acid (B) ascorbic acid
(C) sodium metabisulpbite (D) butylated hydroxy toluene
Q.33. Phosphatidic acid and its derivatives form liposomes.because
(A) in a fu!ly hydrated condition, they arc conical in shape
(B) in a fully hydrated condition they are cylindrical in shape
(C) they contain only non-polar moieties in !heir structures
(D) their saponification values are unusually low.
Q.34. Will! re;;:;:rd to !he ·Standards for Sterile Watqr for Injection, IP.
the 'residue on
evaporation' limit is
(A) higbee than Water for Injection, IF (C) same as that of the Wakr for ｬｾｪ･｣ｴｩｯｮ＠ www.examrace.com
JP
(B) lower than Water for htiection, IP (D) no such stand ard is prescribed in the monograph
Q.3S. ·The number ofpe;ks ｧｩｾ･ｮ＠ by the 1H NMR spec/rum o.fl-methy/-1-pentene is
(A)4 (B)5
(C)6 (D)3
Q.36. In HPLC, the analytical performance improves when
(A) particle ､ｩ｡ｾ･ ｴ ･ｲ＠ is increased (B) particle diameter is reduced
(C) ｣ｯ｡ｾｲ＠ parttcles are paired w ith shorter columns (D) low temperature is used '
Q.37. Increase mthe ｾ ｬ･ｮｾ＠ ofconjugatimt of a double bonded system results in
(A) hyperchromtc shtft (B) hypochromic s hift
(C) hypsochromic shift (0) bathochromic shift

Q . 38-54 are multiple selection items. P, Q, R, S ar e the options. Two of th ese

o tions are correct. Choose the corred combination amon A, B, C a nd D.
Q.38. ａｬｫ｡ｯｩ､ｾ＠ deriredfrom omithine are
(P)cocaine
(Q) colchicine
(R) hyoscyamine
(S)emetine
(A)Q, S (B) P. R
(C) S, R (D) P, Q
Q.39. AIM barbadensis has two ofthe fallowing characters
( P) ihe drug obtained is white in colour and has a biner taSte
(Q) The drug is opaque. yellowish brown to chocolate. brown in ﾫ＾ ｬ ｯｵ ｲ ｾ Ｍ breaks with a
waxy fracture
(R) The drug has a pungent odour and is amorphous under the microscope
(S) Under the microscope, acicular crystals are visible
(A) P, R (B) P, S
(C)Q.S (D)Q.R
Q.40. TaG?Calimus is a macrolide·amibiotic, which bears rhcfollowillg olfributes
(P) produced from Streptomyces hygroscopicus and is chemicnlly related to cyclosporine
·(Q) binds with cytoplasmic peptidyl-propyl-isomera.se and can be useful in liver and
kidney transplants
(R) produced from Streptomyces tsukubaensis and is c hemically un related to cyclospori ne
(S) an inhibitor of pyrimidine synthesis, used in rheumatoid arthritis
(A)P, Q . (B)P,S
(C) Q, R (D) Q, S
Q.41. Mctfarmin acts by two mechanisms
(P) Increasing insulin secretion
(Q) Inhibiting a-glucosidase
(R) Decreasing hepatic glucose production .
(S) Increasing insulin action in muscle and fat
(A) P, Q (8) R, S
(C) P, R (0) Q, S
Q.42. Metabolic oxidation of carbo11-nitrogen. carbon-oxyge11 011d carbon-sulphur systems
principally involves two basic types ofbio-trcmsformutioll processes.
(P) Hydroxylation of the a-<:arbon atom attached directly to the heteroatorn
(Q) Mixed function oxidase system also oxidizes carbon atom adjacent to carbonyl and
imitio functions
(R) Hydroxylation or oxidation oftbe hetero-atom only
(S) Microsomal hydroxylation at allylic carbon atom
(A) P, R (B)P, S
(C) Q. R (D) R, S
QAJ. The silver salt ofsulphadiazine. SILVADENE. is 011 ｾ｛ｦ･｣ｴ ｩ ﾷ｣＠ topical alllimicrobial ｡ｾｵＯＱ＠ in
bums because tif its two imponanr al/rrbllles
(P) Broad spectrirm of activity
(Q) Active against Pseudomonas spp.
(R) TI1e salt is only very slightly soluble and it does not penetrate the cell ｷｾｬ Ｌ＠ instead it
acts on the external cell structure
(S) The salt is highly soluble and hence it is rapidly absorbed
(A) P, Q (B) R S
(C)Q, R . ＨｄＩｐＺｾ＠
Q.44. In the syntheszs ofchlorpheniramine, two important ingredients required ora
(P) 4-chloro benzyl cyanide
(Q) 4-chloro pyridine
(R) 2-chloro benzyl cyanide
(S) 2-chloro pyridine
(A) P, Q
(B) P, S
(C)Q, R (D) R. S

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 Q.4S . Zeta potential
(P) is the differ ence in potential betwe
en the surfa ce of the t .ghtly bound layer
electr oneut ral regio n and the
(Q) is the poten tial at the solid surfa ce
of the suspe nded partic le
(R} can be positive, 7.;ero or negative
(S) is the electr other mody namic poten
tial
(A) P, R
(C)Q .R (13) P, S
Q .46. Two ofthe official.stQ/tdard! for uncoated (D) P, Q
tablets as per IP are
sh"pe ｾ ｄＩ＠
(Q) friabi lity
(R) disint egrati on time
(S) unifo rmity of weigh t
(A)P ,Q
(C) Q, R
(B)P ,S
Q.47 . As per Schedule '0' of the Dn1g (D) R. S
s £tnd Cosmetu:s Rules t945. the minim
Coefficients for Grade 1 and Grode 3 Black um Ridea/ Walker
disinfectant fluids are
(P) 18
(Q) 10
(R)S
(S) 14
(A) P, R
(B) Q, S
(C)P ,S
Q.48. The IR spectrum ofon organ ic liquid can be (O)R,S
token by placing it between a pair ofpolis
plates made of hed
(I>) NaCI
(R) KBr (Q) FeS04
(S) AIC I3
lA)P .O
(C) R.S (B)P .S
Q.49. In gas chromatography. derivatisation is desira (O)P.R
ble to
(P) impro ve lhe therm al stability of comp
ounds
(Q) enabl e interaction w ith carrier gas
(R) i.n trodu ce a detec tor orien ted tag into
the molec ule
(S) remove conta minan ts
(A) P, Q
(B) Q, R
(C) P, R
Q.SO. Neutralthio (D) P, S
aliphatic ammo acidsfmmd in proteins ore
{P) Meth ionin e
(Q) Valin e
(R) Cyste ine
(S) Leucine
(A) P, Q
{B) P, R
(C) P, S
Q. 51. Diazoxide, a benzothiazi de deriv (D) R, S
ative produces
(P) vasoc onstri ction by activating ATP
sensitive K+ channe l
(Q) vasod.ilatation by activa ting ATP sensit
ive K+ chann el
(R) inhib ition of insuli n secre tion
(S) stimu lation of insulin secre tion
(A) P,R
(C) P, S .
(B)Q ,R
Q.S2. Q, S (0)
17te principle ofELISA is based on these two
observations
(P) Antib odies and antig eos can attach
to solid- phase s upports and still maim
immu nolog ical capabi lities ain their full
{Q) Antib odies comp lel< with enzymes
allow ing full separation of antigen molec
(R) Antig ens and antibo dies can be bonde ules
d to enzym es and result ing comp lel<es
fully funct ional bolh immunologically are sti ll
and enzym atical ly
(S} Enzym atic action is cruc ial for
converting the ·antig ens to rende r them
bindi ng to antibo<lies suita ble for ·
{A) P,Q
(B) P, R
(C) Q,R
Q.53. Which ofthe following are likely to be goad (D) Q, S
targets for designing antihypertensive drugs
(P) }:12 histarnine recep tor ?
(Q) Proto n pump
(R) Calcium chann el protein
(S) ｾＭ｡､ｲ･ｮｧｩ｣＠ receptor
(A//? (J
(C)P, R (B} R, S
(D)Q , S
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 Q. 54.
The characteristics ofthe Sobin v . . . .
(P) It consists oflive.attenuated ::;::: Ｚｴｬｵｭｳｾ｣ｲ､＠ oral/y.for /m:;•l!ntion of olio
Ｈ
ＨｾＩ＠ It •s ｧ･ｾｲ｡ｬｹｩｯｴ＠ used. in infants bel ｴｬｾ･＠
) It contams serum ant''--d' h
ｬｭｕｉｾｯｧｩ
ow months of age
｣ ｬ＠ types o f the ｾｩｯｶ＠
rus
(S) It h h . luv •es t at are active . ·. .•
as_t e nsk of occasionally revertin b agallls.' spc:cofoc ｳｾｲ｡ｩｯ＠ ofpolioviruses
. assoctated paralytic poliomyelitis g ack to ｶｾｲｵｬ･ｮｴ＠ strams, resulting iu vacciue-

Q. 55-70 are Matching Exercises

Match Grou I with Grou II and identif the correct combination
Q.55. Mucilages are plant produCJS formed ut differeut parts of the plum
Group-1 (Plant part from which it is formed) Grou p-U (Example)
(P) Cell wall of seed epidermis (I) Fenugreek
(Q) Endodermis (2) Senna
(R) Epidermis ofleaf (3) Squill
(S) Special secretory cells (4) Linseed
(a) (b) (c) (d)
f>-4 P-4 P-3 P-1
Q-1 Q-2 Q· l Q-2
R-2 R-1 R·2 R-3
S-3 S-3 S-4 S-4
Q. 56. G r oup-I (Crude Drugs) Group-O (Chemical nature of their
chiefconstituents)
(P) Ergot (I) Imidazole alkaloids
(Q) Jaborandi (2)' Steroidal compo\)nds
(R) Kurchi (3) Indole alkaloids
(S) Pterocarpus (4) Condensed taunins
(a) (b) (c) (d)
P-3 P-3 P-3 P-3
Q-2 Q-1 Q-1 Q-4
R-4 R-2 R-4 R-2
S-1 S-4 S-2 S-1
Q.57. Group-1 (Common reagents used in pharmacognosy) Group-IT (Uses) .
( P) 5% aqueous· chlor-zinc-iodine solution ( I) disintegmtion of sclcrenchymatous
tissue
(Q) phloroglucinol and hydrochloric acid solution (2) staining lignifled walls pi•lk or red
'(R) a mixture of equal parts of ether and ethanol (3) removal of fixed oils and fats
( S) a mixture of equal parts of chromic acid and (4) staining cellu lose walls blue
·nitric acid
(a) (b) (c) (d)
P-4 P-1 . P-2 P-3
0·2 Q-3 Q-1 Q-4
R-3 . R-2 R4 R-1
S-1 . S-4 S-3 S-2
Q.58. G roup-I (Reactions) Group-11 (Names)
(P) n-propyl-m-tolyl ketone is converted to (I) Perkin condensation
m-(n-butyl) toluene using NH2-NH2 and a
base at 200•c
(Q) phenol is treated with chloroform and {2) WoiiT-Kishn.e r reduction
. aqueous sodium hydroxide by which, (a) (b) (c) (d)
. salicylaldeb.yde is fomted P-2 P-2 p.J P-4
(R) beozophenoqe and. methylene triphenyl (3) Witt iss reaction Q-4 Q-3 Q·3 Q-3
phospharane are treated and tlie pr6duct R-3 R-4 R-4 R-1
formed is 1,1 diphenyl ethene S-1 S-1 S-2 S-2
.(S) benza!dehyde is treated with acetic (4) Rei tuer-Tiema.nn reaction
anhydride in the presence of sodiuin acetate,
3 phenyl-propenoic acid· is· formed
Q.59. G rouP:'l ｾｎ｡ｭ･＠ of the enzyme) Group-11 (Description)
(P) Sut•lams. . · . . (I) Mixture 9f proteolytic enzymes
obtained from the pi!1eapple plant
used for soft tissue inflammlttion
and oedema (a) (b) (c) (d)
ｾｑＩ＠ Urokinase (2) It is a tissue plasminogen activator P-3 P-1 P-4 P-4
' produced by recombinant DNA Q-4 Q·J Q-2 Q-3
technology R-2 R-4 R-3 R-2
(R) Altepll!Se (3) Obtained from tissue culture of
(S) Bromelains
S-1 S-2 S-1 S-1
human kidnevs and ｩｾ＠ a
(4) A proteolytic enzyme obtained g.lycosylated serine protease
from cultures of Bacillus subtilis consisting of two polypeptide
used to dissolve ｮｾｲｯｴｩ｣＠ tissue in chains connected by a s ingle
burns, bed . sores and ulcerated d isu Iphi de bond www.examrace.com
wounds.
 Q. 60. G roup-I (Physic alform ofsubstances) Group-O (J<heo/ogica/ proper ties)
(P) Castor oil (I) Plastic flow ·
{Q) Concen trated floccul ated suspens ion
(2) Pseudo plast ic flow
(R) Liquid dispersion of methyl cellulose
(3) Dilatant flow /
(4) Newtonian flow
(S) Pastes of sinal! deflocculated particles
(a) (b) (c) (d)
P-4 P-3 P-2 P-1
Q-1 Q-2 Q-3 Q-4
R-2 R-1 R-4 R-3
S-3 S-4 S-1 S-2
Group -JI
Q. 61. G roup-1
(P) Crystal growth (I) Griffin
(Q) pH scale ·{2) Sorensen
(R) HLB scale
(3) DLVO theory
(4) Ostwald ripening
(S) lnterparticular force
(a) (b) (c) (d)
P-4 P-3 P-2 i>-t
Q-2 Q-1 Q-4 Q-3
R-1 R-2 R-3 R-4
S-3 S-4 S-1 S-2
Group -ll (Effect on water quality /
Q. 62. G roup-! (Metho d ofpurification)
(P) Entrainment preventive distillation (I) CPU value and endotoxin content
usually increases
(2) Pyrogen free water
(Q) Simple distillation
(3) Endotoxins and pyrogens are not
(R) Reverse osmosis
removed
(4) Small organic molecules (mol.
(S) Jon-exchange
wt., approximately less than 200)
are not removed
(a) (b) (c) (d)
P-1 P-4 P-2 P-3
Q-4 Q-1 Q-3 Q-2
R-3 R-2 R-4 R-1
S-2 S-3 S-1 S-4
Group-11 (Mechanism)
Q.63. G roup-I (Drug)
(P) Rifabutin
(I) Inhibition of viral DNA synthesis
.(Q) Penciclovir (2) Inhibition of mycobacterial RNA
polymerase
' (3) Inhibition of HIV proteas e
(R) lmiquimod
(4) lmmunomodulation
(S) Amprenavir
(a) (b)_ (c) (d)
P-1 P-3 P-2 P-4
Q-2 Q-4 Q-1 Q-3
R-4 R-1 R-4 R-2
S-3 S-2 S-3 , S-1
Q. 64 · G rot•p-I (Responsesllncidems)
(P) Paise transmitter ｇｲｯｵｾ ｉ＠ C-!Jioactive substances)
(Q) St. Antony 's fire (I) Htstamme
(R) Triple response (2) Methyldopa
(3) Morphine
(S) Srraub phenomenon
(a) (b) (c) (4) Ergot alkaloid
(d)
P-2 P-1 P-3 P-4
Q-4 Q-4 Q-2 Q-3
/ R-1 R-3 R-1
R-2
S-3 S-2 S-4 S-1
·Q. 65,. Group -1 (Adverse effects)
(P) Reye's syndrome Group -II (Drug,r) (a) (h) (c) (d)
(Q) Hypertrichosis (I) Cltloramphenicol P-J P-3 P-4 P-4
(R) Grey baby syndrom e (2) Morphine Q-2 Q-4
(3) Aspirin
Q- 1 Q-3
($) Pinpoint pupil . R-4 R-1 R-2
(4) Minoxidil R-2
S-3 S-2 S-3 S-1
Q.66. Groap -I (Technique Used)
Group -D (Analy liculmethod of
(P) ｐｯ ｬ ｡ｲｯｧｾｰ｢ｹ＠ eval110tion)
(I) Potential-volume curve (a) (b) (c) (d)
(Q) Potentiometry
(2) Current-potential curve P-1 P-2 P-3
(R) Conductometr y P-4
(S) Amperomctry (3) Conductance-volume curve .Q-3 Q·l Q-2 . Q-1
(4) Current-volume curve R-2 R-3 R-4 R-2
S-4 S-4
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S-1 S-3
 Q-67. Gr oup-1 (Ty pe ofRa
1
diation) Gr oap -D Ｈｗｴｮｾ･ｬｧｨＩ＠
(P) Radio frequency
(I} > \OOmm (u) (b) (c) (d)
(Q )U V
(2) 200 - 380 nm P- 1 P-3 P-1 P-2
(R) X-ray Q-4
(3) I'Opm - lOn m Q-2 Q- 2 Q-1
(S) Mid-IR R-3
(4) 2.5 -5 0 I1JTI R- 1 R-3 R-4
S-? S-4 S-4 S-3
Q. 68. G.-oup-1 (Spray
ing reagents used in Gr ou p-U (Type ofsub
c/Jromutographic metho swnce}
ds)
(P) SbC I in CHCl3
3 ( 1) Carboxvlic aci d (a) (b) (C) VI)
(2) Aldehyde or Ke ton P-2 P-3 P-1 P-4
(Q ) BromocJeSOI green e
(3) Steroid Q-1 Q-1 Q-3 Q- l
(R ) Aniline ·phthalate
(S) 2,4 dinitrophenyl , {4) SugaJ: · R.-4 R-4 R-2 R-2
ｾｲ｡ｺｴｮ･＠ S·2 s-4 S-3
U (Tesrorganfs.mJor
S-3
Q. .. .
69 _ G rou p-I (Antibiotics)
0
G ro p- microbiolo
gical assay IP)
( 1) ｓｾ｡ｰｨｹｬｯ｣ｏｃｵｳ＠ ｡ｾｮｳ＠
(P) ｅｲｹｴｨｯｭｾｩｮ＠
(Q} ｛Ｉｯｸｩ｣ｾ｜＠ (2 } Pseudomonas ｡･ｲｵｧｭｾ＠ (a) (b) (c) ld}
(3) Saccharomyces cer P-2
(R) ｃ｡ｲ｢･ｭ｣ＱＮｾ＠ evts•a e P-4 .P-3 P-1
)
(4 Mi crococcus luteus. Q-2 Q-2 Q-4
(S) Am pbo ten cln B Q-1
R-2 R-1 R-4 R-3
S-1
Q .70 . ｇｾ ｵ Ｑ＠ ｰＭ Ｈｈｯｲｾｮ･Ｉ＠ ·
Grou p-l l (Action)
' I) u odulateS extens. ｡ｳｯ､ｩｬｴｾＳ＠ S-4 S-3
(P) ｖ｡ｳｯｰｾｓｉｏ＠ ' ,.., ive v .
(2) Helper homlOne corticotroP1un
(Q) ()x-ytOCID to
releasing hofnlOOC
(3) Stimula tes • of
· (R) Brad·Arini n ｳｾｮＱｬ･＠
Ｌｾ＠ components of m1lk
(4) Responds to suekl·111 g reflex an ·d
·
(S) Prolac tm (b)
(a) (c) (d) est
p. p.3 radiol
P-2 P-I 4
Q-1
Q-4 Q- 2
R-3
ｑＭ ｒｾ＠ R-4
R- 1 -4
ｾ＠ s S-1 ,B .
Co mm on_
d2 ts for Q uestio ns 11
. s the coe a-l eav es ＠ ｾ ｮ ｡ 12_ --• ine .. a p)'Sd>Ostim Ｐｾ＠
Sin ce anc•ent ｴｵｾ･＠ ncb m....,.... ulant. have bee
• ma sticatory agent.
the So uth Am enc ans
'h /kaloidconcelllrat｡ｳｾ＠ JO · /eaves 1'fil')'from
Q.7 1. ｾａ＠ IIIn CO - o;.
ｾＭＴ Ｅ＠ CD (8) 0.7-1.5 • ·
(C)O.OI -0.02% (0) 9- \1 o/o
Q.7 2. Cccaine, the
alkaloid derived from
(A ) increasing noradr coca leave.t ac/ s by
enaline synthesis
(B) inhibiting monoa
mine oxidase
(C ) inhibiting catech
ol-0-methyl transferas
(D ) inhibiting ｮｯｲ｡､･ e
ｮｾ ｊｩｮｾ＠ re-u ota k•
Co mm on d ats_ fo r Q uestto ns
Ch lor am buc il TP IS a
Q.73. Ch lor am buc cytotoxic age nl
il is a derivarh-e of
(A ) amino phenyl but
yric acid
(C ) amino phenyl gly (B) amino phenyl cap
Q.1 4. Identification cine roi c acid
rest pre scr ibe d in TP is: (D ) dia min o dipjlenyl
2 M hyd roc hlo ric aci 0. 4 g ofthe dru g is ext
d three ｴｾｳＮ＠ i-acted wuh i 0 ml quanti
me rcu ric iodide sol uti To 10 ml qua nti ty of ties of
on is odd ed. wh ich yie the extract, 0.5 ml of
(A ) yellow coloured lds por ass ium
precipitate
(C ) buf f coloured pre (B) yellow col our ed
cipitate solution
ｾＮＷＵ＠ Ch lor am buc il is ass (D ) red coloured precip
ayed as per IP by ritratiJ itate
(A ) 0.1 M sodium hyd tg a di1111e acetone soluri
roxide on ofthe drug with
(C ) 0.2 M percbl ori c (B) 0.1 M hydrochlo
aci d ric acid
Sta te me nt for link ed (D) 0.1M silver nit rat
An sw er Qu est ion s 16 "
Dried stigma of Crocus and n
Q. 76. On e ofthe imp sat ivu s con tains several constituen
ortanJ con.srituents is ts.
(A) Picrocrocin
(C) Picrasmin (B) Picroside I
Q.77. On hydrolysis, (D ) Gymnemic acid
the abo ve gives a pro
(A) Cro cet in duc t wh ich is resportsib
le for the characterisri
(C} Quercetin (B) Saffranal c od ow
(D) Crotonic acid

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 StMement for Linked A
A glycosaminoglycan is ｲＬＢｳｷＺｾ＠ Questions 78 & 79
Q.78. An ｡ｮｴｩ｣ｯｧｵｬ｢ｾ＠ ﾷ ｡ｯｾ ｮ＠ 10 the granules of mast cells.
(A) Warfarin Ｌ ｾ＠ J mmoglyr:an is

(C) Vitamin K (B) Heparin

Q.79. (D) Aspirin
' The anticoagulant selected
(A) lowering the affinit ｦｯ［ｾｶ･＠ ClefS ｾｙ＠
(B) degrading fibrin andyfi'· . ree plasmmogen
•vrmogen
(C) binding tO antitllrOmbin ill
(D) antagonizing co-factor functions of vitamin K

Statem ent for Unked Answer Questions 80 & 81

droxy-6, 7-dimethoxy
Prazosin, an antihypertensive drug, is prepared as follows: 2,4-dihy
POCI / PCI , followed by amidation. The prcxluct X is treated
quinazolino is treated with 3 5
with a reagent Y to get Praz.osin.
Q.80. The produc t X is
(A) 4-Amino-3-chloro 6, 7-dimethoxy quinazofine
(B) 2-Chloro-4-amino 6, 7-dimethoxy quinazoline
(C) 4-Amino-2-chlor 6, 7-dimethoxy quinazoline
(D) 4-Amino-6-chlor 2, 7-dimethoxy quinazoline
Q.Sl. The reagent Y is
(A) 1-(2-Furoyl)-pyridine (B) 1-(2-Furoyl)-piperazine
(C) 1-(2-Pyridyl)-piperazine (0) 1-{2-Furoyl)-pyrimidine

St;tem ent for Linked Answer Questions 82 & 83

The powder of a ｶｩｾ｣ｯｳｴｹ＠ builder is dispersed with high s.hear in 1/5 to 1/3 of the required
is finely dispersed, the
amount of water pre-heat to so•c to 90•C. Once the powder
ed
Mcxlerate stirring causes prompt dissolution.
.volume is made up with iee cold water or ice.
Q.82. T11e powder is·
(A) bentonite (B) sodium carboxymethyl cellulose
(C) veegum (0) methyl cellulose
y, the above solution should br:
Q.83. For obtaining maximum clarity, hydralio11 and 1•iscosit
cooledfor abom an hour to
"( A) ooc to we (B) 25°C
(C) '$o·c· (D) 3:s•c

Statement for ｌｬｮｫｾ､＠ Answe r Questions 84 & 85

£and A:;';, can be interconverted using u fonnula, from which its molnr absorptivity or
absorbance can be calculated.
Q.84. . The formula is
(A) e ］ａＺｾ［Ｌ＠ X mol. wt/1000 (B) e ］ ａＺｾＮ＠ X mol. wt/10

, '(C)E= A::, Xeq. wt/JOOO- (O)e = A::, Xeq.,vt/100

of297; an equival ent weight of 148.5 and 1111 A:;:, of
Q.8S.' A compou nd has a molecular w/Jig)U
' 742 at 309 nm. Its molar absorpt ivityjs
(B) II 01.87
· (A)220 .37
(C) 110.18 (0)220 37.4

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ANSWER Key –GATE-2007 Pharmaceutical Sciences

1 2 3 4 5 6 7 8 9 10
D B C D B C B B A A
11 12 13 14 15 16 17 18 19 20
B C C B C C C B B A
21 22 23 24 25 26 27 28 29 30
B A B C B D D B B D
31 32 33 34 35 36 37 38 39 40
A D B B B B D B C C
41 42 43 44 45 46 47 48 49 50
B C C A A D A D C B
51 52 53 54 55 56 57 58 59 60
D B B C A B A A D A
61 62 63 64 65 66 67 68 69 70
A C C A B B C B A A
71 72 73 74 75 76 77 78 79 80
B D A C A A B B C C
81 82 83 84 85
B D C B D

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