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Mycophenolate Mofetil

Mycophenolate mofetil is an immunosuppressive drug used for renal, cardiac, and hepatic transplants. It is administered orally and converted to the active metabolite mycophenolic acid. Common adverse effects include constipation, nausea, headache, diarrhea, vomiting, stomach upset, and trouble sleeping. Nurses monitor for side effects and infection, check lab tests regularly, and educate patients on contraindications like vaccination and breastfeeding while taking the drug.

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100% found this document useful (1 vote)
876 views1 page

Mycophenolate Mofetil

Mycophenolate mofetil is an immunosuppressive drug used for renal, cardiac, and hepatic transplants. It is administered orally and converted to the active metabolite mycophenolic acid. Common adverse effects include constipation, nausea, headache, diarrhea, vomiting, stomach upset, and trouble sleeping. Nurses monitor for side effects and infection, check lab tests regularly, and educate patients on contraindications like vaccination and breastfeeding while taking the drug.

Uploaded by

AndyPua
Copyright
© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
Available Formats
Download as DOC, PDF, TXT or read online on Scribd
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Drug Name Dosage Action Indication Adverse Effects Contraindica Nursing Responsibility

and Route tion


Mycophenolic Constipation, n Hypersensitiv  Lab tests: Monitor CBC weekly for
Mycophenol Renal,
acid is an ausea, headac ity to first month, weekly for second and
ate immunosuppr Cardiac, And he, diarrhea, v mycophenola third months, then once per month
Mo essive drug. Hepatic omiting, stoma te mofetil; for first year. If neutropenia
Mycophenolat develops, withhold dose and notify
fetil Transplant ch upset, gas, vaccination,
e mofetil is a physician.
tremor, varicella;
prodrug or trouble pregnancy  Periodically monitor and report
(inactive form) abnormalities for any of the
sleeping may (category C),
of following: Kidney and liver function,
occur. If any of lactation;
mycophenolic serum electrolytes, lipase, and
these effects children <5 y.
acid (MPA). amylase; blood glucose; routine
last or get
Following oral urinalysis.
worse, tell
administration
your doctor  Monitor for and report any S&S of
,
or pharmacistp sepsis or infection.
mycophenolat
romptly.
e mofetil is  Avoid taking OTC antacids
rapidly simultaneously with mycophenolate
absorbed and mofetil. Separate the two drugs by 2
hydrolyzed h.
(converted) to
MPA. MPA is  Explain to the patient “Do not
the active breast feed while taking this drug.”
metabolite
which has
pharmacologi
cal activity.

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