Scribd
Upload
234 views

Genetics MCQ

1. A heritable factor which makes a protein. 2. Alleles. 3. A mutation is thought to be the cause of the existence of the HbS allele in sickle cell disease. 4. They had sequenced the entire base sequence of human genes.

Uploaded by

ibdp
Copyright
© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
Available Formats
Download as DOC, PDF, TXT or read online on Scribd
234 views

Genetics MCQ

1. A heritable factor which makes a protein. 2. Alleles. 3. A mutation is thought to be the cause of the existence of the HbS allele in sickle cell disease. 4. They had sequenced the entire base sequence of human genes.

Uploaded by

ibdp
Copyright
© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
Available Formats
Download as DOC, PDF, TXT or read online on Scribd
You are on page 1/ 3

1.Which of the statements below is the best definition of "a gene"?

All the genetic information in an organism

A heritable factor which makes a protein

A heritable factor made of a length of DNA which influences a specific characteristic.

The location on a chromosome of a specific length of DNA

2.Which biological term refers to the different forms of a gene which differ by just a few bases?

Alleles

Genotypes

Genes

Proteomes

3.In sickle cell disease there are two alleles for the protein haemoglobin. These are called HbS and
HbA .
What is thought to be the cause of the existance of the HbS allele?

An infection

DNA replication

Protein synthesis

A mutation

4. What was it that the Human Genome Project's international consortium achieved in 2003 when
they announced the successful completion of the Human Genome Project?

They had found the sequence of all amino acids in all human proteins

They had found the function of all human genes.

They had sequenced the DNA bases of all known genes

They had sequenced the entire base sequence of human genes


In the rat genome sequencing project of 2004, Dr Richard Gibbs and his researchers reported that the rat
genome is smaller than the human genome, and slightly larger than mouse genome.
However, they also found that the rat genome contains about the same number of genes as the human
and mouse genomes.

Species Human Rat Mouse

Genome size 2.9 billion base pairs 2.75 billion base pairs 2.6 billion base pairs

Estimated gene number 20000 to 30000 20000 to 30000 20000 to 30000

Chromosome number 46 42 40

Which of the following suggestions could be an explanation for such a large difference in the
genome size of these three species when the number of genes is thought to be so similar?

The genes in humans have a longer length.

Most of the differences in the genome size are found in non-coding regions of the DNA, where
there are no genes.

Humans have more chromosomes, and therefore more DNA base pairs

The differences are smaller than the precision of the method, so are not significant differences.

The diagram below shows the change which differentiates the HbA allele from the HbS allele in
sickle cell disease.
Which of the following answers best describes this type of mutation.

It is a base substution mutation

It is a frame shift mutation.

It is a base deletion mutation

It is an inversion of one part of a chromosome

You might also like