MSc-CHEMISTRY

(Under CBCS)
FIRST YEAR 2017-18
TWO SEMESTERS: 15 WEEKS EACH
TEACHING AND EXAMINATION SCHEME OF FIRST SEMESTER
CORE COURSE:

CODE DESCRIPTION HRS/W HRS/SEM EXAM CCA ESE TOTA

L
MSCH111 Group Theory &
4 60 3 HRS 30 70 100
Chemical Bonding
MSCH112 Organic Chemistry-I 4 60 30 70
3 HRS 100
MSCH113 Physical Chemistry-I 4 60 30 70
3 HRS 100
MSCH114 Analytical Chemistry-I 4 60 30 70
3 HRS 100
Total Theory 400
Laboratory Course I: 30 70
MSCH121 9 135 12HRS 100
Inorganic Chemistry
Laboratory Course II: 15 35
MSCH122 6 90 6 HRS 50
Physical Chemistry
Total Practical
150
Grand Total 550
Note:
1. A board of two examiners (one internal and one external) will be appointed for
conducting the examination of each laboratory course.
2. In practical exam one major and minor experiment will be allotted in each lab course.
3. In inorganic mixture student can consult book for basic radicals after reporting the
concern groups.
4. In organic mixture student can consult book for confirmatory test of the compounds
after reporting the initial physical properties, element detection, functional group &
melting/boiling point of the compound.
5. Practical Exam shall be conducted in two days where ever required(12 Hours)

SKILL BASED COURSE IN CHEMISTRY FOR CHEMISTRY STUDENTS:

STUDENT HAVE TO OPT ONE SKILL BASED PAPER FROM EITHERPAPER:
SKCH131(A) or (B).
THEORY PRACTICALS
CODE DESCRIPTION
HRS/W HRS/SEM HRS/W HRS/SEM
SKCH131(A) Cosmeticology And Cosmetic
2 30 2 30
Preparation-I
SKCH132(B) Technology Of Dyes 2 30
2 30
 MSCH111- GROUP THEORY & CHEMICAL BONDING
Stereochemistry and bonding in main group compounds
VSEPR, Walsh Diagrams of tri, tetra and penta atomic molecules, dπ-pπ bonds,
15
Unit 1 Bent’s rule and energetics of hybridization, some simple reactions of covalently
HRS
bonded molecules: atomic inversion, berry pseudorotation, substitution reactions
and free radical reactions.
Metal Ligand Bonding
Limitations of Crystal field theory, molecular orbital theory: octahedral, tetrahedral 15
Unit 2 and square planar complexes, π- bonding and molecular orbital theory, explanation HRS
of position of the ligands in Spectrochemical series using MOT, Comparison with
CFT.
Molecular Symmetry and Symmetry Groups:
Symmetry elements and operations, proper axis of symmetry & rotation, symmetry
planes & reflection, center of symmetry & inversion, improper axis of symmetry &
improper rotation and identity.
Definition and Theorems of Group Theory: Defining properties of Group, 15
Unit 3 subgroup and classes; group multiplication tables. HRS
Molecular Point Groups:Identification of molecular point groups, molecules of
low, high & special symmetry, molecules containing multiple higher order axes,
Schonflies symbols, systematic assignment of point groups. Descent in symmetry
with substitution.
Matrix Methods in Symmetry
Introduction to matrices, types of matrices, equal matrices, matrix mathematics,
block factorization of large matrices, transformation matrices.
Representations of groups by matrices (representation for the Cn, Cnv, Cnh, Dnh 15
Unit 4 etc. groups to be worked out explicitly). Reducible and irreducible representations, HRS
Character of a representation. Great Orthogonality Theorem (without Proof) and its
Importance. Construction of character tables, character tables of C2v, C3v and C4v
point groups, Mulliken symbols for IRs and structure of character table. Standard
reduction formula for reduction of reducible reprsenttion, direct products.
Symmetry and Chemical bonding:
15
Orbital symmetries & overlap, hybridisation scheme in Linear, trigonalplanar,
Unit 5 HRS
tetrahedral, squarepyramidal& trigonal pyramidal; molecules with π bonding as in
trigonal planar, tetrahedral, octahedral& benzene
Suggested Readings:
1. Advanced Inorganic Chemistry, F.A. Cotton and Wilkinson, John Wiley.
2. Inorganic Chemistry, J.E. Huhey, Pearson.
3. Inorganic Chemistry, Shriver and Atkins, Oxford University Press
4. Modern Inorganic Chemistry, William L. Jolly, Tata McGraw Hill
5. Concepts and Models of Inorganic Chemistry, Bodie E. Douglas and Darl H. McDaniel,
Oxford
6. Inorganic Chemistry, GeryWulfsberg, Viva
7. Chemistry of the Elements, N.N.Green Wood and A. Earnshow, Elsevier.
8. Inorganic Chemistry, James E house, Elsevier.
9. Chemical Applications of Group Theory. F.A. Cotton
10. Molecular Symmetry and Group Theory, Robert L Carter, John Wiley & Sons
11. Symmetry andSpectroscopy of Molecules, K Veera Reddy, New Age
12. Advanced Inorganic Chemistry, Asim K Das
 MSCH112-ORGANIC CHEMISTRY-I
Nature of bonding in Organic Molecules:
Delocalized chemical bonding: Conjugation, cross conjugation, resonance
hyperconjugation, bonding in fullerenes, tautomerism.
Aromaticity in benzenoid and non-benzenoid compounds: Alternant and non-
Unit 1 15 HRS
alternant hydrocarbons, Huckel's rule, energy level of π-molecular orbitals,
annulenes,homoaromaticity, (PMO approach).
Bonds weaker than covalent bonds: addition compounds, crown
ethercryptants&cyclodextrinsand rotaxanes& their structure.
Stereohemistry I:
Conformational analysis: Cycloalkanes, decalins, effect of conformation on
Unit 2 reactivity, conformation of sugars, and steric strain due to unavoidable crowding. 15 HRS
Stereochemistry of the compounds containing nitrogen, Sulphur and phosphorus.
Stereochemistry II:
Elements of symmetry, chirality, molecules with more than one chiral center,
threo and erythro isomers, methods of resolution, optical purity, enantiotopic and 15 HRS
Unit 3
diasterotopic atoms, groups and faces, stereospecific and stereoselective
synthesis, Asymmetric synthesis. Optical activity in the absence of chiral carbon
(biphenyls, allenes and spiranes), chirality due to helical shape.
Reaction Mechanism:
Structure and Reactivity: Kinetic and thermodynamic control of reactions.
Hammond's postulate, Curtin-Hammett principal, Potential energy diagrams,
transition states and intermediates, methods of determining mechanism, isotope
Unit 4 effects, Hard and soft acids and bases, Generation, structure, stability and 15 HRS
reactivity of carbocations, carbanions, free radicals, carbenes and nitrenes,
Effects of structure on reactivity resonance and field effects, steric effect,
quantitative treatment , The hammett equation and linear free energy
relationship, substituent and reaction constants: Taft equation
Pericyclic Reactions:
Molecular orbital symmetry, frontier orbitals of ethylene, 1, 3-butadiene, 1, 3,5-
hexatriene and ally1 system. Classification of pericyclic reactions. Woodward
Hoffman correlation diagrams, FMO and PMO approach.
Electrocyclic Reactions: Conrotatory and disrotatory motions, 4n, 4n+2
Unit 5 systems, 2+2 addition of ketenes, 1,3 dipolar cycloadditions and cheleotropic 15 HRS
reactions.
SigmatropicRearrangemnts: Suprafacial and antarafacial shifts of H,
sigmatropic shifts involving carbon moieties, 3, 3 and 5, 5 sigmatropic shifts.
Rearrangements, Claisen, Cope andaza-cope rearrangements. Fluxional
tautomerism, ene reaction
Suggested Readings:
1. Advanced Organic Chemistry-Reactions, Mechanism and structure, Jerry March, John
Wiley.
2. Advanced Organic Chemistry, F.A Carey and R.J. Sundberg, Plenum.
3. A Guide Book to Mechanism in Organic Chemistry, Peter Sykes, Longman.
4. Structure and Mechanism in Organic Chemistry, C.K. Ingold, Cornell University press.
5. Organic Chemistry, T.T. Morrison and R.N. Boyd, Prentice-Hall Modern Organic
Reactions H.O. House, Benjamin.
6. Principles of Organic Synthesis. R.O.C. Norman and J.M Coxon, Blackie Academic &
Professional.
7. Pericyclic Reactions, S.M. Mukherji, Macmillan, India.
8. Reaction Mechanism in Organic Chemistry S.M. Mukherji and S.P. Singh. Macmillan.
9. Sterochemistry Organic Compounds, D.N. Asipuri, New Age International.
10. Sterochemistry of organic Compounds, P.S. Kalsi, New Age International.
11. Pericyclic Reactions, Jagdamasingh.
 MSCH113-PHYSICAL CHEMISTRY-I
Chemical Dynamics I:
Ionic reactions, Kinetic salt effects, steady state kinetics, kinetic and
Unit 1 thermodynamic control of reactions. Dynamic chain (hydrogen-bromine 15 HRS
reaction, pyrolysis of acetaldehyde). Photochemical reaction (hydrogen-oxygen
and hydrogen-chlorine reactions), decomposition of ethane.
Chemical DynamicsII:
Fast Reactions: General features of fast reactions, study of fast reactions by
flow method, relaxation method and flash photolysis method, NMR method. 15 HRS
Unit 2
Dynamics of molecular motions, probing the transition state, dynamics of barrier
less chemical reactions in solution, dynamics of unimolecular reaction,
Lindeman, Hinshelwood, RRK and RRKM theories of unimolecular reactions.
Catalysis &enzyme:Heterogeneous and Homogeneous catalysis, advantages
and disadvantages. Catalytic cycles.
Heterogeneous catalysis: Preparation methods, characterization and
15 HRS
Unit 3 quantification of surface active sites, kinetics of heterogeneous catalytic
reactions. Structure of adsorbed species. Supported catalysts and metal-support
interaction. Catalyst deactivation and regeneration.
Enzyme: introduction, types and characteristics, kinetics of enzyme reactions
Macromolecules:
Polymer: Definition types of polymers, electrically conducting, fire resistant,
liquid crystal polymers, kinetic of polymerization, mechanism of polymerization.
15 HRS
Unit 4 Molecular mass, number and mass average molecular mass, molecular mass
determination (osmometry, viscometry, diffusion and light scattering methods)
sedimentation, chain configuration of macromolecules, calculation of average
dimensions of various chain structures.
Electrochemistry:
Electrochemistry of solutions: Debye-Huckel-onsagar treatment and its
extension, Debye-Huckel-Jerrum mode, ion-solvent interaction, born model.
Electro- Kinetic phenomenon and quantitative treatment of Zeta potential.
Thermodynamics of electrified interface equations. Derivation of electrocapilary 15 HRS
Unit 5 Lippmann equation (surface excess). Structure of electrified interface.
Helmholtz, Guoy-chapman and Stern models.
Over potentials. Exchange current density, Butler Volmer equation, Tafel plot.
Introduction to corrosion, theories, forms of corrosion. Corrosion monitoring and
prevention methods.
Suggested Readings:

1. Physical chemistry, P.W. Atkins, ELBS.

2. Chemical Kinetics, K.J. Laidler, Megraw-Hill.
3. Kinetics and Mechanism of Chemical Transformation, J. Rajarman and J. Kuriacose,
McMillan.
4. Micelles: Theoretical and Applied Aspects, V Moroi, Plenum.
5. Modern Electrochemistry Vol, I and Vol. II, J.O.M. Bockris and A.K.N. Reddy Plenum.
6. Introduction to Polymer Science V.R. Gowarkar, N.V.Vishwananathan and J. Sridhar,
Wiley Eastern.
7. Principles and practice of heterogenous catalysis, Thomas J.M. and Thomas M.J., John
Wiley
8. Concepts of modern catalysis and kinetics, Chorkendoff I.B. and Niemantsverdriet J.M.
 MSCH114-ANALYTICALCHEMISTRY-I
Fundamentals of Chemical Analysis:
Classification of analytical method, significance, Sensitivity and Selectivity of
Analytical methods, Sampling, Accuracy & precision, Errors: types of errors,
error distribution curve, avoid, standard Deviation; Calibration curve and
Unit 1 Correlation Coefficient; linear regression; student 't' test, Analysis of Variance
15 HRS
(ANOVA). Good lab practices.
Quality control, Quality assurance, International standards & government
standards in chemical analysis.
Spectroscopic Techniques-I
Basic principles of the spectrophotometry, basic instrumentation: single beam
and double beam spectrophotometer. 15 HRS
Unit 2 Flame Photometry & Atomic Absorption Spectroscopy (AAS): Principle,
General layout of instrument and applications.

Spectroscopic Techniques-II
Inductively Coupled Plasma Spectroscopy (ICPS): ICP -AES, ICP-MS, OES,
Theory, instrumentation and applications. 15 HRS
Unit 3 Fluorescence Spectroscopy: Principle, Fluorescence, Phosphorescence basic
Instrumentation and their applications. Chemiluminscence.
Nephelometry and Turbidometry: Principle, instrumentation and applications.
Seperation Technique
Solvent extraction- Principle, methodology and applications, Synergistic
15 HRS
Unit 4 extraction: determination of nickel, crown ether for ion association complex.
Organic reagents like dithiol, diketones, oxinedithizone, cuproin, cupferron,
dimethylglyoxime and dithiocarbamates in solvent extraction and electrophoresis
Chromatography: Introduction.
HPLC: Theory, General layout of equipment, detector working principle (u.v
detector, luminescencedetector, refractive index detectors)and applications.
15 HRS
Unit 5 HPTLC:Principle, advantage over TLC, mobile and stationary Phase
Gas chromatography: Theory, General layout of equipment, detectors (Flame
ionization, Photoionization detector, coupled GC detector) and applications.
Gas Chromatography –Mass spectrometry

Suggested Readings:
1. Vogel's Textbook of Quantitative Chemical Analysis, G.H. Jeffery, J. Bassett, J. Mendham
and R.C. Denney, Publ ELBS, Longman, UK
2. Basic Concepts of Analytical Chemistry, S.M. Khopkar, Wiley Eastern.
3. Fundamentals of Analytical Chemistry, D.A. Skoog, D.M. West and F.J. Holler. Pubi WB
Saunders.
4. Analytical Chemistry, G.D. Christian, John Willy & Sons.
 MSCH121-LABORATORY COURSE-I: INORGANIC CHEMISTRY
I. Qualitative Analysis: Qualitative estimation of the inorganic mixture for six radicals including
interfering acid radicals, their combinations and insoluble oxides, sulphates and halides
including rare earth elements.
II. Quantitative Analysis:
a. Separation and determination of two metal ions Cu-Ni, Ni-Zn, Cu-Ag etc, involving
volumetric and gravimetric methods.
b. Estimation of three constituent in the given mixture (one gravimetrically and
one volumetrically and one colorimetrically).
III. Chromatography
a. Separation of cations and anions by circular Paper Chromatography.

MSCH122-LABORATORY COURSE-I: PHYSICAL CHEMISTRY

I. Chemical Kinetics
1. To compare the strengths of HCl and H2SO4 by studying the kinetics of hydrolysis of an
ester.
2. Determination of the effect of Change in temperature on the rate constant of acid
hydrolysis of ester & calculation of activation energy.
3. Determination of the effect of Change of concentration of reactant -and catalyst on the rate
of acid hydrolysis of ester.
4. Determination of the effect of Ionic strength of the media on the velocity constant of an
acid hydrolysis of an ester.
5. To study the effect of acid strength on the reaction of acetone and iodine.
II. Adsorption: To study the adsorption of acetic acid/oxalic acid by activated charcoal and
verification of Freundlich and Langmuir's isotherms.
III. Electrochemistry /Conductometry
1. To determine the strength of weak acid using NaOHconductometrically.
2. To determine the strength of strong and weak acids in a given mixture conductometrically.
IV. Colorimetry:
1. To test the validity of Beer-Lambert law using colorimeter/ spectrophotometer and
determination of the unknown concentration of a solution.

Suggested Readings:

1. Practical Physical Chemistry, A.M. James and F.E. Prichard, Longman

2. Findley's Practical Physical Chemistry, BP Levitt, Longman.
3. Experimental Physical Chemistry, RC Das and B Behera, Tata McGraw Hill
4. Experimental physical Chemistry by F. Daniel and others (International Student Edition)
 5. Advanced Practical Physical Chemistry, JB Yadav, Goel Publishing House.
6. Advanced Experimental Chemistry, Vol. I Physical JNGurtu and R Kapoor, S. Chand & Co.

MSCHSC131(A): COSMETICOLOGY AND COSMETIC PREPARATION-I

THEORY:
Fundamentals of cosmetic science. Classification of cosmetics. Structure and function of skin
and hair. Formulation, preparation and packaging of cosmetics for lotion, suspension,
vanishing cream, paste, shaving cream, liquid detergent, ointment.
EXPERIMENTS: Topical Preparations
1. To prepare sunscreen calamine suspension.
2. To prepare and submit vanishing cream.
3. To To prepare and submit Calamine lotion
4. To prepare and submit Zinc Sulphate lotion.
5. To prepare and dispense zinc oxide paste.
6. To prepare and dispense shaving cream.
7. To prepare and dispense astringent lotion.
8. Prepare and submit liquid detergent.
9. To prepare and submit boric acid ointment.

SUGGESTED READING:

1. Ansel H. C, Introduction to Pharmaceutical Dosage Forms, K M Varghese and,

Bombay.
2. Jellinek J. S., Formulation and Function of Cosmetics, John Wiley and sons, NY.
3. B.M. Mithal, A Handbook of Cosmetics, Vallabh Praakashan Delhi
4. P. P. Sharma, “ Cosmetics- formulation, Manufacturing and Quality control” , Vandana
Publication, Delhi
5. Indian Pharmacopoeia, I.P., Edition II, Year 1966,
6. Cooper and Guns “Dispensing for Pharmaceutical Students”, CBS Publisher, New
Delhi
 MSCHSC131 (B): TECHNOLOGY OF DYE

THEORY
Introduction, classification of dyes, general idea about the synthesis of different dye
intermediates and synthetic dyes (azoic, acidic, basic, disperse, mordent and
Sulphur dyes). Dyeing processes of acrylic fibers. Finishes to improve colour
fastness, effect of temperature on the dying process, pigment for textile colouration.

PRACTICAL
1. Preparation of methyl orange.
2. Preparation of malachite green.
3. Preparation of natural dye.
4. Effect of mordents and modifiers on the process of dying.(Alizarin red
using Fe+2 , Mg+2,Al+3, Cu+)
5. To study the interaction of natural dyes with different fibers.
6. To study the interaction of synthetic dyes with different fibers.
7. To study the optimum PH for dying cotton cellulose fabrics.
8. Testing of dyes.
9. Thin layer chromatography of dyes.

SUGGESTED READING:

1. Synthetic Dyes, Dr. G.R chatwal, Himalaya Publishing House

2. Colours Chemistry: Synthesis, Properties and applications of organic Dyes and pigments,
Heinrich Zollinger, Wiley-VCH
3. Synthetic Dyes, O.D Tyagi, M.Yadav , Anmol Publication Pvt Ltd.
4. Industrial chemistry by B.K Sharma.
5. The chemistry and application of Dyes, David R. Waring and GeofferyHallos.
 TEACHING AND EXAMINATION SCHEME
SECOND SEMESTERCORE COURSE:
CODE DESCRIPTION HRS/W HRS/SEM EXAM CCA ESE TOTAL
COORDINATION
MSCH211 4 60 3 HRS 30 70 100
CHEMISTRY
MSCH212 ORGANIC CHEMISTRY-II 4 60 30 70
3 HRS 100

MSCH213 PHYSICAL CHEMISTRY-II 4 60 30 70

3 HRS 100

MSCH214 ANALYTICAL CHEMISTRY-II 4 60 30 70

3 HRS 100
Total Theory
400
LABORATORY COURSE III: 30 70
MSC221 9 135 12HRS 100
ORGANICCHEMISTRY
LABORATORY COURSE 15 35
MSCH222 6 90 6HRS 50
IV:ANALYTICALCHEMISTRY
Total Practical
150
Grand Total 550
Note:
1. A board of two examiners (one internal and one external) will be appointed for
conducting the examination of each laboratory course.
2. In practical exam one major and minor experiment will be allotted in each lab course.
3. In inorganic mixture student can consult book for basic radicals after reporting the
concern groups.
4. In organic mixture student can consult book for confirmatory test of the compounds
after reporting the initial physical properties, element detection, functional group &
melting/boiling point of the compound.
5. Practical Exam shall be conducted in two days where ever required(Hours)

SKILL BASED COURSE IN CHEMISTRY FOR OTHER STUDENTS:

THEORY PRACTICALS
CODE DESCRIPTION
HRS/W HRS/SEM HRS/W HRS/SEM
MSCHSC231 FUNDAMENTAL CONCEPT IN
CHEMICAL CALCULATIONS: 2 15 2 30
STOICHIOMETRY

SKILL BASED COURSE OFFERED BY OTHER DEPARTMENTS FOR

CHEMISTRY STUDENTS:

STUDENT HAVE TO OPT ANY ONE OF SKILL BASED PAPER FROM SKILL
BASED PAPERS OFFERED BY OTHER DEPARTMENTS.
 MSCH211-COORDINATION CHEMISTRY
Reaction mechanism of Transitions metal complexes
Energy profile of a reaction (transition state or activated complex) nucleophilic and
electrophilic substitution, factors responsible for types of substitution reaction.
Introductory classical reaction of Henry-Taube in octahedral complexes (inert and 15
Unit 1
labile complexes), classification of mechanism of. Acid hydrolysis, factor affecting HRS
acid hydrolysis, base hydrolysis, conjugate base mechanism (SN1CB) Evidences in
favour of conjugate base mechanism, anation reactions, Substitution reaction
without metal-ligand bond cleavage (Special reference to Co(III) complexes).
Substitution in square planer complexes:
Trans effect, mechanism of substitution reaction, polarization theory and π bonding
theory.
15
Redox reaction:
Unit 2 HRS
Classification of mechanism of octahedral complexes (inner and outer sphere
reaction; adjacent attack, remote attack. and bridged outer sphere reaction).
Electron transfer reaction, mechanism of one electron transfer reaction: outer sphere
reaction, Inner sphere reaction, bridge intermediate mechanism.
Isomerisation and Racemisation Reactions:
Linkage isomerization, geometrical isomerization in square planar and octahedral
complexes, racemisation: inter and intramolecular mechanism, isomerisation and 15
Unit 3 racemisation of tris chelates of unsymmetrical chelating ligands, structural changes HRS
in complexes containing terdentate ligands, optical isomerisation on tetrahedral
complexes and configurational changes in some planar complexes
Electronic spectra of Transition Metal Complexes
15
Spectroscopic ground states term, correlation, Orgel and Tanabe sugano diagrams
Unit 4 HRS
for transition metal complexes (d1 to d9 states) and calculation of Dq, B and β
parameters
Charge Transfer Spectra
General Introduction to charge transfer spectra and types of spectra.
Ligand to metal and metal to ligand charge transfer spectra of transition metal
15
complexes.
Unit 5 HRS
Magnetic Properties of Transition Metal Complexes: Anomalous magnetic
moments, magnetic exchange coupling and spin crossover.
ORD and CD: Introduction, assignment of absolute configuration in optically
active metal chelates and their configuration

Suggested Readings:
1. F.A. Cotton and Wilkinson: Advanced Inorganic Chemistry, John Wiley.
2. J.E. Huhey: Inorganic Chemistry, Harper and Row.
3. N.N.Green Wood and A. Earnshow: Chemisryof the element, Pergamon.
4. A.B.P. Lever: Inorganic Electronic Spectroscopy, Elsevier
5. R.L.Carlin: Magnetochemistry, Verlag.
6. G. Wilkinson, R.D. Gillars and J.A. McLeverty: Comprehensive Coordination Chemistry eds.
Pergamon.
7. F. Basolo and R.G. Pearson: Mechanism of Inorganic Reaction, Wiley Eastern.
8. D. Banerjia: Coordination Chemistry, Asian.
9. Advanced Inorganic Chemistry, Asim K Das
 MSCH212-ORGANIC CHEMISTRY-II
Aliphatic Nucleophilic Substitution
The SN2, SN1, mixed SN1 and SN2 and SET mechanisms.
The neighbouring group mechanism, neighbouring group participation by π and
σ bonds, anchiomeric assistance.
Classical and nonclassical carbocations, phenonium ions, norbornyl system.
The SNi mechanism.
Nucleophilic substitution at an allylic, aliphatic trigonal and a vinlyic carbon.
Unit 1 15 HRS
Reactivity effects of substrate structure, attacking nucleophile, leaving group and
reaction medium, phase transfer catalysis and ultrasound, ambident nucleophile,
regioselectivity.
Aliphatic Electrophilic Substitution
Bimolecular mechanisms- SE2 . The SE1 mechanism, electrophilic substitution
accompanied by double bond shifts. Effect of substrates, leaving group and the
solvent polarity on the reactivity
Aromatic Electrophilic Substitution
The arenium ion mechanism, orientation and reactivity, energy profile diagrams.
The ortho/para ratio, ipso attack, orientation in mono and substituted ring
systems. Quantitative treatment of reactivity in substrates and electrophiles. 15 HRS
Unit 2 Diazonium coupling, Vilsmeir reaction, Gattermann-Koch reaction.
Aromatic NucleophilicSubstitution:TheSNAr SN1 benzyne and SRN1
mechanisms. Reactivity effect of substrate structure, leaving group and attacking
nucleophile. The von Richter, Sommelet-Hauser, and Smiles rearrangements.
Free Radical, Reactions:
Types of free radical reactions, free radical substitution mechanism, mechanism
at an aromatic substrate, neighbouring group assistance.
Reactivity for aliphatic and aromatic substrates. Reactivity in the attacking 15 HRS
Unit 3
radicals. The effect of solvents on reactivity.
Allylic halogenation (NBS), oxidation of aldehydes to carboxylic acids, auto-
oxidation, coupling of alkynes and arylation of aromatic compounds by
diazonium salts, Sandmeyer reaction and Hunsdiecker reaction
Addition to Carbon-Carbon Multiple Bonds:
Mechanistic and sterochemical aspects of addition reactions involving
electrophiles, nucleophiles and free radicals, regio- and chemoselectivity,
orientation and reactivity. Addition to cyclopropanering. Hydrogenation of
double and triple bonds, hydrogenation of aromatic rings.Hydroboration.
Michaelreaction. Sharpless asymmetric epoxidation.
Addition to Carbon-Hetero Multiple Bonds 15 HRS
Unit 4 Mechanism of metal hydride reduction of saturated and unsaturated carbonyl
compounds, acids, esters and nitrites. Addition of Grignard reagents, organozinc
and organolithium reagents to carbonyl and unsaturated carbonyl compounds.
Wittig reaction.
Mechanism of condensation reactions involving enolates Aldol, Knoevenagel,
Claisen, Mannish, Benzoin, Perkin and Stobbe reactions.
Hydrolysis of esters and amides, ammonolysis of esters
Elimination Reactions:
The E1, E2 and E1cB mechanisms and their spectrum, stereochemistry of E1 and
E2 reactions and elimination from cyclic compounds. Orientation of the double 15 HRS
Unit 5 bond. Reactivity effects of substrate structures, attacking base, the leaving group
and the medium.
Mechanism and orientation in pyrolytic elimination.
Suggested Readings:
1. Advanced Organic Chemistry-Reactions, Mechanism and Structure, Jerry March, John Wiley.
2. Advanced Organic Chemistry, F.A. Carey and R.J. Sundberg, Plenum.
3. A Guide Book to Mechanism in Organic Chemistry, Peter Sykes, Longman.
4. Structure and Mechanism in Organic Chemistry, C.K. Ingold, Cornell University Press.
5. Organic Chemistry, R.T. Morrison and R.N. Boyd, Prentice-Hall Modern Organic Reactions,
H.O. House, Benjamin.
6. Principles of Organic Synthesis, R.O.C. Norman and J.M. Coxon, Blackie Academic &
Professional.
7. Pericyclic Reactions, S.M. Mukherji, Macmillan, India.
8. Stereochemistry of Organic Compounds, D. Nasipuri, New Age International.
 MSCH213-PHYSICALCHEMISTRY-II
Quantum Chemistry
Introduction to Exact Quantum Mechanical Results: The Schrodinger
Unit 1 equation and the postulates of quantum mechanics. Discussion of solutions of the 15 HRS
Schrodinger equation to some model systems viz., particle in 1 and 3-
dimensional box, the harmonic oscillator, the hydrogen atom.
Quantum Chemistry
Electronic Structure of Atoms: Russell-Saunders terms and coupling schemes,
spectral terms for pn configurations and dn configurations.
Magnetic effects: Perturbation theoryNormal and anomalous Zeeman effects 15 HRS
Unit 2 and Stark effect.
Molecular Orbital Theory: Huckel molecular orbital (HMO) theory of linear
conjugated systems, bond order and charge density calculations. Applications of
HMO to ethylene, allyl, butadiene and cyclobutadiene system.
Classical Thermodynamics
Partial molalproperties: Partial molar free energy - chemical potential, partial
molal volume and partial molal heat content. Gibbs Duhem equation, variation of 15 HRS
Unit 3 chemical potential with temperature and pressure, chemical potential for ideal gas.
Thermodynamic derivation of law of mass action. Concept of fugacity and determination
of fugacity. Thermodynamic derivation of phase rule, application of phase rule to three
component systems
Statistical Thermodynamics
Concepts of phase space, microstate and macrostate, Ensemble averaging,
Canonical, grand canonical and microcanonical ensembles, Maxwell-Boltzman
distribution law (using Lagrange's method of undetermined multipliers).
Partition functions translational, rotational, vibrational and electronic partition
15 HRS
Unit 4 functions, calculation of thermodynamic properties in terms of partition
functions- Energy, specific heat at constant volume and constant pressure,
entropy, work function, pressure Gibb's free energy and chemical potential.
Chemical equilibria and equilibrium constant in terms of partition functions,
Fermi-Dirac statistics distribution law and Bose-Einstein statistics distribution
law.
Non Equilibrium Thermodynamics
Thermodynamic criteria for non-equilibrium states, entropy production and
entropy flow, entropy balance equations for different irreversible processes (e.g.
15 HRS
Unit 5 heat flow, chemical reaction etc.) transformations of the generalized fluxes and
forces, non-equilibrium stationary states, phenomenological equations,
microscopic reversibility and Onsager's reciprocity relations, electrokinetic
phenomena, diffusion, electric conduction

Suggested Readings:
1. Physical Chemistry, P.W. Atkins, ELBS.
2. Introduction to Quantium Chemistry, A.K. Chandra, Tata McGraw Hill.
3. Quantum Chemistry, Ira N. Levine, Prentice Hall.
4. Coulson's Valence, R. McWeeny, ELBS.
5. Physical Chemistry, S. Glasston, Princeton, London.
6. Non Equilibrium Thermodynamics, Fitts, McGraw Hills, New York.
7. Fundamentals of Chemical Thermodynamics, E.N. Yeremin, Mir Publishers
 MSCH214: ANALYTICAL CHEMISTRY-II
Thermal analysis:
TGA, DSC (differential scanning calorimetry), DTA (differential thermal
Unit 1 15 HRS
analysis): principle, methodology and application

Radio analytical Techniques

Radioactive Decay Process-radioactive decay rates, counting statistics,
Instrumentation
15 HRS
Unit 2 Neutron Activation Method Theory, instrumentation, destructive and
nondestructive method, Applications.
Isotopic Dilution Method: Principal, methods and Applications

Polarography
Polarography: Principles, classification of polarographic techniques, types of
polarographic currents, instrumentation, factors affecting polarographic wave, 15 HRS
Unit 3 pulse polarography, and differential pulse polarograph,square wave
polarography.Applications

Voltammetry: Voltammetric principles, hydrodynamic voltammetry, stripping

voltammetry
15 HRS
Unit 4 Cyclic voltammetry: Cyclic wave form,criteria for reversibility of
electrochemical reactions, quasi-reversible and irreversible processesQualitative
and Quantitative analysis

Sensors
Ion Selective Electrode: Classification,Application
Sensors:Definition-Classification-Optical,Thermal,Electrochemical,Condution 15 HRS
Unit 5 sensors, Gas sensorsBiosensors:Introduction, Working of Glucose Biosensors

Suggested Readings:

1. Modern Polarographic Methods in Analytical Chemistry, AM Bond, Marcel Dekker.

2. Electrochemical Methods: Fundamentals and Applications, AJ Bard and LR Faulkner.
3. Principles of Instrumental Analysis, DA Skoog and JL Loary, WB Saunders.
4. Handbook of Instrumental Technique for Analytical Chemistry, F.Settle, Prentice Hall.
5. Laboratory Technique in Electronanalytical Chemistry, PT Kissinger and HR Heinaman,
Marcel decker.
6. Analytical Chemistry, GD Christian, J Wiley.
7. Chemical Sensors, RW Cattrall, Oxford University Press.
8. Principles of Instrumental Analysis, DA Skoog, DM West and FJ Holler, WB Saunders
 MSCH221: LABORATORY COURSE V: ORGANIC CHEMISTRY
Qualitative Analysis
Separation, purification and identification of compounds in given binary mixture (one
liquid and one solid and solid- solid mixture) separation using chemical methods as well.
Quantitative Analysis
a. Determination of the percentage or number of hydroxyl group in an organic compound
by acetylation method& periodate method.
b. Estimation of amines/phenols acetylation method.
c. Determination of Iodine and Saponification values of an oil sample.
d. Estimation of glucose by colorimeter.
e. Estimation of formaldehyde by iodometry.
Organic Preparation
a. Aromatic electrophilic substitution: p-nitroacytanilide & p-bromoacetanilide
b. Cannizaro-reaction: benzaldehyde

Suggested Readings:
1. Practical Organic Chemistry, SP Bhutani & Aruna Chhikara, Ane Books India
2. Elementary Practical Organic Chemistry Part I & II, Arthur I Vogel, CBS
3. Advanced Practical Organic Chemistry, NK Vishnoi, Vikash Publication

MSCH222: LABORATORY COURSE IV: ANALYTICAL CHEMISTRY

I. Spectrophotometer
1. To determine the concentration of two components in the mixture of
K2Cr2O7& KMnO4/ CoCl2& NiSO4
2. To determine the pKa of indicator (Methyle Red) in aqueous medium.
II. Fluorometry: To determine the concentration of quinine sulphate, Vitamin B
(Riboflavin) and Aluminium.
III. Nephelometry: To determine the concentration of sulphate content in water sample.
IV. Flame photometry
1. Estimation of Na+ and K+.
2. Estimation in a mixture (Na+ and K+).
3. To determine the Na and K content in the given soil sample.
V. Water and Waste Water examination
1. To determine the concentration of Fluoride, nitrite and phosphate
spectrophotometrically.
2. Determination of dissolve oxygen in water sample
3. Determination of chemical oxygen demand (COD) in water sample.
VI. Atomic Absorption Spectroscopy: To determine the trace metal (Pb, Cu, Zn) in soil
sample using AAS

Suggested Readings:

1. Handbook of Instrumental Technique for Analytical Chemistry, F. Settle, Prentice Hall.

2. Vogel’s Text book of Quantitative Inorganic Analysis, Basset RC, Denny GH, Jeffery and
Mandan J, ELBS.
MSCHSC231: FUNDAMENTAL CONCEPT OF CHEMICAL CALCULATIONS:
STOICHIOMETRY

(For students of other departments)

THEORY:
Atomic weight, molecular weight, empirical formulae and its determination ,the mole
concept:elementry problem ,problem based on equation: stoichiometry , equivalent weight and
chemical equivalence, concentration units and volumetric calculation.

Practical:
Numerical problem based on above concept.
Preparation of solution: primary and secondary standard.
Dilution of solutions.

Suggested Books:
(1) Modern approach to chemical calculation by R.C.Mukherjee,Bharti Bhavan P&D
(2)Stoichiometry by B.I.Bhatt and S.B.Thakore.
(3) Stoichiometry and process calculations: K.V.Narayanan and B.Laxmikutty
 TEACHING AND EXAMINATION SCHEME
THIRD SEMESTERCORE COURSE:
2018-19
CODE DESCRIPTION PD/W PD/SEM EXAM CIA ESE TOTAL
MSCH311 ORGANIC SPECTROSCOPY 4 60 3 HRS 30 70 100
SOLID STATE, SURFACE 4 60 30 70
MSCH312 3 HRS 100
CHEMISTRY & CATALYSIS
ORGANOTRANSITION METAL 4 60 30 70
MSCH313 3 HRS 100
CHEMISTRY
ELECTIVE
4 60 30 70
MSCH314(A) ORGANIC SYNTHESIS-I 3 HRS 100

OR
4 60 30 70
MSCH314(B) MATERIAL CHEMISTRY 3 HRS 100
TOTAL THEORY
400
LABORATORY COURSE V: 30 70
MSCH322 9 135 12 HRS 100
INVESTIGATORY PROJECT
LABORATORY COURSE IX:
MSCH323 6 90 6 HRS 15 35 50
ORGANIC CHEMISTRY
GRAND TOTAL 550

Note:
1. A board of two examiners (one internal and one external) will be appointed for
conducting the examination of each laboratory course.
2. In practical exam one major and minor experiment will be allotted in each lab course.
3. In inorganic mixture student can consult book for basic radicals after reporting the
concern groups.
4. In organic mixture student can consult book for confirmatory test of the compounds
after reporting the initial physical properties, element detection, functional group &
melting/boiling point of the compound.
5. Practical Exam shall be conducted in two days where ever required (Hours).

SKILL BASED COURSE IN CHEMISTRY FOR CHEMISTRY

STUDENTS:
STUDENT HAVE TO OPT ONE SKILL BASED PAPER FROM EITHER
PAPERS: MSCHSC331(A) or (B).
THEORY PRACTICALS
CODE DESCRIPTION HRS/W HRS/SE HRS/W HRS/SE
M M
MSCHSC331(A) COSMETICOLOGY AND
2 30 2 30
COSMETIC PREPARATION-II
MSCHSC331(B) TESTING OF ADULTRATION 2 30
2 30
IN MILK & MILK PRODUCTS
 MSCH311: ORGANIC SPECTROSCOPY
Ultraviolet and Visible Spectroscopy
Various electronic transitions (185-800 nm), Beer-Lambert law, effect of solvent on
electronic transitions, ultraviolet bands for carbonyl compounds, unsaturated 15
Unit 1 carbonyl compounds, dienes, conjugated polyenes Woodward- Fieser rules for
HRS
conjugated dienes and carbonyl compounds, ultraviolet spectra of aromatic,
heterocyclic compounds and steric effect in biphenyl.
Mass Spectrometry
Introduction, ion production EI, CI, FD and FAB, factors affecting fragmentation,
15
ion analysis, ion abundance. Molecular ion peak, metastable peak, Mc Lafferty
Unit 2 rearrangement and Nitrogen rule. High resolution mass spectrometery .Mass HRS
spectral fragmentation of organic compounds containing common functional
groups.
Infrared Spectroscopy
Characteristic vibrational frequencies of alkanes, alkenes, alkynes, aromatic
compounds, alcohols, ethers, phenols and amines. Detailed study of vibrational
frequencies of carbonyl compounds (ketones, aldehydes, esters, amides, acids,
anhydrides, lactones, lactams and conjugated carbonyl compounds).Effect of 15
Unit 3 hydrogen bonding and solvent effect on vibrational frequencies, overtones, HRS
combination bands and Fermi resonance.FTIR.IR of gaseous, solids and polymeric
materials.
Optical Rotatory Dispersion (ORD) and Circular Dichroism (CD):
Definition, deduction of absolute configuration, axial halo- ketone and octant rule
for ketones.
Nuclear Magnetic Resonance Spectroscopy
General introduction and definition, chemical shift, spin- spin interaction,
shielding mechanism, mechanism of measurement, chemical shift values and
correlation for protons bonded to carbon (aliphatic, olefinic, aldehydic and
15
aromatic) and other nuclei (alcohols, phenols, enols, carboxylic acids, amines,
Unit 4 amides &mercapto), chemical exchange, effect of deuteration, complex spin-spin HRS
interaction between two, three, four and five nuclei (first order spectra), virtual
coupling. Stereochemistry, hindered rotation, Karplus curve-variation of coupling
constant with dihedral angle. Simplification of complex spectra-nuclear magnetic
double resonance, contact shift reagents, solvent effects.
Carbon-13 NMR Spectroscopy
General considerations, chemical shift (aliphatic, olefinic, alkyne, aromatic, hetero-
aromatic and carbonyl carbon), coupling constants
15
Fourier transform technique, nuclear Overhauser effect (NOE).
Unit 5 HRS
Two-dimension NMR spectroscopy
COSY, NOESY, DEPT, INEPT, APT and INADEQUATE techniques.
Problems of the structure elucidation using above mentioned spectroscopic
techniques.
Suggested Readings:
1. Practical NMR Spectroscopy, M.L. Martin, J.J. Delpeuch and G.J. Martin, Heyden.
2. Spectrometric Identification of Organic Compounds, R.M. Silverstein, G.C. Bassler
and T.C. Morrill, John Wiley.
3. Introduction to NMR Spectroscopy, R.J. Abraham, J. Fisher and P. Loftus, Wiley.
4. Application of Spectroscopy of Organic Compounds, J.R. D yer, Prentice Hall.
5. Spectroscopic Methods in Organic Chemistry, D.H. Williams, I. Fleming, Tata McGraw-
Hill.
 MSCH312: SOLID STATE, SURFACE CHEMISTRY & CATALYSIS
Solid state chemistry-I
General principles, experimental procedures.
Unit 1 Crystal Defects, Perfect and imperfect crystals, intrinsic and extrinsic defects 15 HRS
point defects, line and plane defects. Thermodynamics of Schottky and Frenkel
defect formation, colour centers.
Solid State Chemistry-II
Electronic Properties and Band Theory
Metals, insulators and semiconductors, band theory of solids (qualitative
treatments), band structure of metals, insulators and semiconductors. Intrinsic
and extrinsic semiconductors, p-n junctions. 15 HRS
Unit 2 Superconductors factors affecting the super conductivity, magnetic properties,
persistent current and BCS theory of superconductors.
Optical properties, photoconduction. Magnetic Properties, Classification of
materials, Magnetic domains, hysteresius.Organic Solids. Electrically conducting
solids, organic charge transfer complex- new superconductors
Surface Chemistry-I
General structural features and behaviour of Surfactants: general use of charge
types, effect of hydrophobic group, anionic, cationic, nonionic and zwitter ionic
surfactants
Adsorption:
15 HRS
Unit 3 Estimation of surface area (BET equation), surface films on liquids,
Micelles: Surface active agents, Classification of surface active agents,
micellization, hydrophobic interaction, critical micellar concentrations (CMC),
factors affecting the CMC of surfactants, counter ion binding to
micelles,psuedophase model of micelles catalysis (proximity effect).

Surface Chemistry-II
Solubilization of surfactants: Solubilization in aqueous media; locus of
solubilization, factors determining the extent of solubilization, effects of
solubilization 15 HRS
Unit 4
Detergency and surfactants: Mechanism of cleaning process, removal of
soil from substrate, suspension of soil in bath and prevention of redeposition, dry
cleaning, skin irritation, effect of water hardness and chemical structure of
surfactants and its detergency.
Phase Transfer catalysis& ultrasound: Definition and importance of
15 HRS
Unit 5 phase transfer catalysis, quaternary ammonium and phosphonium salts, crown
eathers and other crypatants. Use of ultrasound.
Suggested Readings:
1. Solid state chemistry and its applications, West A.R., Plenum.
2. Principles of solid state, Keer H.V., Wiley Eastern
3. Solid state chemistry, Chakrabarty D.K., New Wiley Eastern
4. Solid state chemistry: An introduction, Moore E., and Smart L., Chapman Hall, 1996
5. Crystallography made crystal clear: A guide for users of macromolecular models, Rhodes
G., Elsevier, 2006.
6. X-ray diffraction, Warren B., Dover Publications
7. Introduction to crystallography, Sands, D.E., Dover Publications.
8. Principles and practice of heterogenous catalysis, Thomas J.M. and Thomas M.J., John
Wiley
9. Concepts of modern catalysis and kinetics, Chorkendoff I.B. and Niemantsverdriet J.M.
10. Physical chemistry of surfaces, Adamson A.W., Wiley Interscience, 1997
11. Surfactants and interfacial phenomenon, Milton J. Rosen, wileyinterscience.
 MSCH313: ORGANOTRANSITION METAL CHEMISTRY
Organotransition Metal Complex
Definition, Classification and nomenclature
Types of ligendsamd M-L bonding: - lone pair donor, pi bonding electron pair
Unit 1 donor, Hapticity, ambidentate ligands, 15 HRS
18 Electron rule: electron counting, ionic v/s covalent model, compliance and
violation of the rule oxidation state of the metal.
Basic reaction in organometallic chemistry
Oxidative addition, reductive elimination, insertion elimination, ligand
15 HRS
Unit 2 substitution nucleophilic and electrophilic addition and abstraction
Fluxional organometallic compound: Rate of rearrangement and study technique,
fluxional molecules of C. No. 4, 5, 6
Complex of sigma-bonded ligands
Preparation, structure bonding and reaction of alkyl and aryl transition metal
15 HRS
Unit 3 Complexes of pi-bonded ligands: -
Preparation, structure and reaction of alkenes cyclopentadienyl complexes,
arenas, carbonyl complexes
Metal cluster and metal-metal bond
Structures, Isolable analogy, synthesis
15 HRS
Unit 4 Catalysis: Basic terminology turn over, turnover number, turn over frequency,
Dehydrogenation of alkene, Hydroformylation, Monsanto process, Wacker
process, Alkene isomerization, Olefin metathesis
Applications of organometallic chemistry in organic synthesis
Heck reaction, Suzuki – miyaura reaction, Sonagashira reaction, Stille coupling,
15 HRS
Unit 5 Kumada coupling, Pauson – khand reaction, Ullmann reaction, Organo copper
compounds
Application in medicine, agriculture, industries
Suggested Readings
1. Principles and Application of Organotransition Metal Chemistry, J.P. Collman, L.S.
Hegsdus, J.R. Norton and R.G. Finke, University Science Books.
2. The Organometallic Chemistry of the Transition Metals, R.H. Crabtree, John, Wiley.
3. Metallo-organic Chemistry, A.J. Pearson, Wiley.
4. Organometallic Chemistry, R.C. Mehrotra and A. Singh, New Age International.
 MSCH314(A): ORGANIC SYNTHESIS-I
Organometallic Reagents
Principle, preparations, properties and applications of the following in
organicsynthesis with mechanistic details.
Group I and II metal organic compounds
Unit 1 Li, Mg, Hg, Cd, Zn and Ce compounds. 15 HRS
Transition metals
Cu, Pd, Ni, Fe, Co, Rh, Cr and Ti compounds.
Other elements
S, Si and B compounds.
Oxidation
Introduction, Different oxidative processes.
Hydrocarbons- alkenes, aromatic rings, saturated C-H groups (activated
15 HRS
Unit 2 andunactivated).Alcohols, diols, aldehydes, ketones, ketals and carboxylic
acids.Amines, hydrazines, and sulphides.
Oxidations with ruthenium tetraoxide, iodobenzene diacetate and thallium
(III) nitrate.
Reduction
Introduction. Different reductive processes.
Hydrocarbons – alkanes, alkenes, alkynes and aromatic rings.
15 HRS
Unit 3 Carbonyl compounds – aldehydes, ketones, acids and their derivatives
Epoxides.Nitro, nitroso, azo and oxime groups.
Hydrogenolysis.

Rearrangements
General mechanistic considerations – nature of migration, migratory
aptitude, memory
15 HRS
Unit 4 effects. A detailed study of the following rearrangements:
Pinacol-pinacolone, Wagner-Meerwein, Demjanov, Benzil-Benzilic acid,
Favorskii,Arndt-Eistert synthesis, Neber, Beckmann, Hofmann, Curtius,
Schmidt, Baeyer-Villiger, Shapiro reaction.
Polycyclic Aromatic Compounds.
Napthelene,Phenanthrene, Anthracene: Introduction and aromaticity,
general methods for synthesis,reactions and spectroscopic properities
Synthesis of linear ortho-fused and Non- linear ortho fused polynuclear 15 HRS
Unit 5
hydrocarbons:
Napthacene,Benz[a] anthracene, Dibenz[a,j] anthracene,Chrysene, Picene
Synthesis of ortho and peri fused polynuclear hydrocarbons:
Pyrene,Corolene 20-methylcholanthrene and circumanthracene.

Books Suggested:
1. Modern Synthetic Reactions, H.O. House, W.A. Benjamin.
2. Somer Modern Methods of Organic Synthesis, W. Carruthers, Cambridge Univ.
Press.
3. Advanced Organic Chemistry, Reactions Mechanisms and Structure, J. March,
John Wiley.
4. Principles of Organic Synthesis, R.O.C. Norman and J.M. Coxon, Blackie
Academic & Professional.
5. Advanced Organic Chemistry Part B. F.A. Carey and R.J. Sundberg, PlenumPress.
6. Rodd’s Chemistry of Carbon Compounds, Ed. S. Coffey, Elsevier.
 MSCH314(B): MATERIAL CHEMISTRY
Multiphase Material :

Classification and properties of materials, Types of phase diagrams,

Unit 1 Isomorphous, Eutectic, Peritectic, Monotectic and Eutectoid systems, 15 HRS
Calculation of phase amounts from a phase diagram, Phase rule, Ferrous
alloys Fe-C phase diagram, Non Ferro alloys, Phase diagrams of brass and
tin bronze.

Composite Materials:
Definition: composite, matrix materials: polymer, metal, ceramic and
glass matrix.
Unit 2 15 HRS
Reinforcement: dispersion reinforcement, partical reforcement, laminated
reinforcement and fiber reinforcement.
Natural and traditional composites (concrete, asphalt, wood)

Polymeric and advanced materials:Brief idea of following: Insulating

material, Semiconductors, Superconductors, Fullerenes, Optical fibers,
Unit 3 Organic electronic material. 15 HRS
Optical fibers: Refraction, reflection, absorption and Transmission.
Application of Optical phenomena.

Corrosion and Degradation of materials:Introduction, Corrosion of

metal: Electrochemical consideration,Corrosion rates, Passivity,
Unit 4 Corrosion environment. 15 HRS
Corrosion prevention: Corrosion of ceramic materials, Degradation of
polymer: swelling and dissolution, Bond Rupture, Weathering.

Surface science of Material :

Surface of metal: Etching of metal surfaces, Metal surface and Vapor

deposition, Sputtering, Solution reaction.

Unit 5 Ceramic surfaces: Oxide ceramic surface, Nonoxide ceramic fiber 15 HRS
surface.

Polymer Surface: General Aspect of Polymer Surface, Chemical

Modification of Polymer Surface, Plasma Modification of polymer
surface.

Suggested Readings:
1. Solid State Physics, NW Ashcroft and ND Mermin, Saunders College.
2. Handbook of Liquid Crystals, Kelker and Hatz, ChemieVerlag
3. Nanostructures materials: Processing, Properties and applications, C. C. Kouch,
William Andrew publications, New York, 2002.
4. Fundamentals of Materials science and Engineering. William D. Callister, Jr, Jhon
Wiley and Sons, Inc.
5. Introduction to Material Chemistry, Harry R. Allcock, Wiley and Sons, Inc.
 MSCH321: INVESTIGATORY PROJECT
Student had to carry out an investigatory project under the guidance of the alloted guide and
submit the dissertation of the same at end of the semester.
Viva voce examination and presentation of the project will be held during the practical
examination.
Marking Scheme for the Project:
CCA : 30 Marks (Including 10 marks of the attendance)
Project Report (Dissertation): 35 Marks
Presentation : 15 Marks
Viva Voce : 20 Marks
 MSCH322: LABORATORY COURSE VI: ORGANIC CHEMISTRY
I. Separation, purification and identification of the components of a
mixture of three organic compounds (three solids or two liquids and one solid, two
solids and one liquid).
II. Extraction of Organic Compounds from Natural Sources (purity of
isolated compound may be checked by chemical test TLC or Paper
chromatography):
a. Isolation of cafeine from tea leaves.
b. Isolation of casein from milk.
c. Isolation of lactose from milk.
d. Isolation of lycopene from tomatoes.
III. Interpretation of IR NMR and Mass Spectra of Organic Compounds.

Suggested Readings:

1. Systematic Qualitative Organic analysis by H. Middleton.

2. Qualitative and Quantitative hand book of Organic analysis by H. Clark
3. Vogel's Text book of practical Organic Chemistry by Vogel
4. Practical Organic Chemistry by N.K. Vishnoi
 MSCHSC331 (A): COSMETICOLOGY AND COSMETIC PREPARATION-II

THEORY:
Fundamentals of cosmetic science. Classification of cosmetics. Structure and function of skin
and hair. Formulation, preparation and packaging of cosmetics gargle, mouthwash, throat
paint, mouth freshener, Astringent lotion.

PRACTICAL:

1. To prepare mouthwash.
2. To prepare and dispense effervescent granules.
3. To prepare and dispense potassium chlorate gargle.
4. To prepare and dispense saline mouthwash.
5. To prepare and dispense throat paint.
6. To prepare and dispense mentho-eucalyptus mouth freshener
7. To prepare and dispense Hydrogen peroxide mouth wash (6 % w/w).
8. To prepare and submit Astringent lotion.

Suggested Reading:

1. Ansel H. C, Introduction to Pharmaceutical Dosage Forms, K M Varghese and,

Bombay.
2. Jellinek J. S., Formulation and Function of Cosmetics, John Wiley and sons, NY.
3. B.M. Mithal, A Handbook of Cosmetics, Vallabh Praakashan Delhi
4. P. P. Sharma, “ Cosmetics- formulation, Manufacturing and Quality control” ,
Vandana Publication, Delhi
5. Indian Pharmacopoeia, I.P., Edition II, Year 1966,
6. Cooper and Guns “Dispensing for Pharmaceutical Students”, CBS Publisher, New
Delhi
 MSCHSC331 (B): TESTING OF ADULTRANTS IN MILK AND MILK PRODUCTS

THEORY:
Introduction, types of milk, general composition of milk, physical and microscopic properties
of milk (fat globules, cellular element, refraction, gravity, conductivity, capillary
phenomenon and curd tension)

Milk products- pasteurized milk, artificial milk condensed milk, milk powder, cream butter,
ghee, cheese.

Artificial coloring, flavors, rancidity in milk products

PRACTICAL:

Detection of adulterants in milk

1. Qualitative determination of starch in milk products (Paneer, Mava etc.).

2. Detection of neutralizers in milk (carbonate & bi carbonate).
3. Test of urea and detergents in milk and milk products.
4. Test of dextrin in milk.
5. Test of nitrate and fluoride in milk and milk products.
6. Test of formalin in milk and milk products.
SUGGESTED READINGS:

1. Manual of methodsof analysis of foods by FSSAI.

2. Milk and milk products by Winton & Winton
 TEACHING AND EXAMINATION SCHEME
FOURTH SEMESTER CORE COURSE:
2018-19

CODE DESCRIPTION PD/W PD/SEM EXAM CIA ESE TOTAL

BIOINORGANIC AND
MSCH411 4 60 3 HRS 30 70 100
SUPRAMOLECULAR CHEMISTRY
MSCH412 HETEROCYCLIC CHEMISTRY 4 60 30 70
3 HRS 100
PRINCIPLES & APPLICATIONS OF 4 60 30 70
MSCH413 3 HRS 100
SPECTROSCOPY
ELECTIVE
4 60 30 70
MSCH414(A) ORGANIC SYNTHESIS-II 3 HRS 100

OR
4 60 30 70
MSCH414(B) NANOSCIENCE 3 HRS 100
TOTAL THEORY
400

MSCH421 LABORATORY COURSE VII: 12 30 70

9 135 100
PHYSICAL CHEMIETRY HRS
MSCH422 LABORATORY COURSE VIII:
6 90 6 HRS 15 35 50
INORGANIC CHEMISTRY
GRAND TOTAL 550

Note:
1. A board of two examiners (one internal and one external) will be appointed for
conducting the examination of each laboratory course.
2. In practical exam one major and minor experiment will be allotted in each lab course.
3. In inorganic mixture student can consult book for basic radicals after reporting the
concern groups.
4. In organic mixture student can consult book for confirmatory test of the compounds
after reporting the initial physical properties, element detection, functional group &
melting/boiling point of the compound.
5. Practical Exam shall be conducted in two days where ever required (Hours).

SKILL BASED COURSE IN CHEMISTRY FOR OTHER STUDENTS:

THEORY PRACTICALS
CODE DESCRIPTION
HRS/W HRS/SEM HRS/W HRS/SEM
MSCHSC431 BASIC SKILLS IN
2 15 2 30
SPECTROSCOPIC ANALYSIS
SKILL BASED COURSE OFFERED BY OTHER DEPARTMENTS FOR
CHEMISTRY STUDENTS:STUDENT HAVE TO OPT ANY ONE OF SKILL
BASED PAPER FROM SKILL BASED PAPERS OFFERED BY OTHER
DEPARTMENTS.
 MSCH411: BIOINORGANIC AND SUPRAMOLECULAR CHEMISTRY
Metal storage Transport and Bio-mineralization
Oxygen carrier (Hb& Mb), ferritin, transferrin and siderophores.
Unit 1 Calcium in Biology: Calcium in living cells, transport and regulation, molecular 15 HRS
aspects of intramolecular process, extracellular binding protein, Ca +2ATPase,
Ca+2 ATPase structure, Ca+2ATPase reaction cycle, intracellular Ca+2 transport.
Metalloenzyme
Zinc enzymes: Carboxy peptidase and carbonic anhydrase.
Iron enzymes: Reactivity and structure of catalase, peroxidase and 15 HRS
Unit 2
cytochrome P450, copper enzymes their Reactivity and structure of superoxide
dismutase (SOD).
Co enzyme vitamin B-12: structure,function,absorption, transport and metabolic.
Metal nucleic acid interaction: Fundamental interaction with nucleic acid,
fundamental reactions with nucleic acid
TRIS(Phenanthroline) metal complexes: Binding with DNA, Applications of
different metal complexes that bind nucleic acid 15 HRS
Unit 3
Metal in medicine: Metal deficiency and disease, toxic effect of metals (Lead,
mercury, cadmium, chromium, aluminum, iron, arsenic, copper, zinc, cobalt),
metal used for diagnosis and chemotherapy with particular reference to
anticancer drugs.
Supramolecular chemistry I
Introduction, concepts and language molecularreorganization: molecular
Unit 4 receptors for different types of molecules including anionic substrates, design 15 HRS
and synthesis of receptor molecules and multiple recognition.
Supramoleculer chemistry II
Supramolecular reactivity and catalysis, supramolecular assemblies,
15 HRS
Unit 5 supramolecular devices, supramolecular photochemistry, molecular and supra
molecular photonic devices, supramolecular electronic, ionic and switching
devices
Suggested Readings:
1. Principles of Bioinorganic chemistry, S.J. Lippard and J.M. Berg, University science books.
2. Bioinorganic chemistry, I Bertini, H.B. Garg, S.J. Lippard and J.S. Valentine, University
science books.
3. Inorganic Biochemistry, Vol I and II Ed. G.S. Eichhorn, Elsevier
4. Progress in Inorganic Chemistry Vol. 18 and 38 ed., J.J. Lippard, Wiley.
5. Supra molecular chemistry, J.M. Lehn, VCH.
6. Bioinorganic chemistry, A.K. Das, Books and allied (P) Ltd.
7. Bioinorganic and supra molecular chemistry, Ajay Kumar Bhagi, G.R. Chatwal, Himalaya
publishing house
 MSCH412: HETEROCYCLIC CHEMISTRY
Nomenclature of heterocycles: Systemic nomenclature of monocyclic, fused &
bridge heterocycles.
Three Membered Heterocyclic Compounds with One Hetero
Unit 1 Atom:Aziridines, Oxiranes and Thiiranes 15 HRS
Three Membered Heterocyclic Compounds with Two Hetero
Atoms:Diaziridines, Diazirines and Oxaziridines
Four Membered Heterocyclic Compounds with One Hetero Atom:
Azitines&Azitidines, Oxitanes, Thietanes and Carbonyl Derivatives: 2-
15 HRS
Unit 2 Azitidinones and Oxetanone.
Five Membered Heterocyclic Compounds with One Hetero
Atom:Tautomerism , Pyrroles, Furans and Thiophenes
Five Membered Heterocyclic Compounds with Two Hetero Atoms:
Pyrazoles, Imidazoles, Oxazoles and Thiazoles. 15 HRS
Unit 3
Bicyclic Ring Systems Derived from Pyrrole, Furan and Thiophene:
Benzopyrroles, benzofurans and benzothiophenes.
Six Membered Heterocyclic Compounds with One Hetero Atom: Pyridines,
Pyrylium salts and Pyrones 15 HRS
Unit 4
Six Membered Heterocyclic Compounds with Two Hetero Atoms:Pyrazines,
Pyridazines and Pyrimidines,Quinazolines and Quinoxalines
Seven Membered Heterocyclic Compounds with Two Hetero Atoms:
Azepines, Oxepins and Thiepins
Unit 5 Bicyclic Ring Systems Derived from Pyridine: Quinoline and Isoquinoline, 15 HRS
Acridines and Phenanthridines
Suggested Readings:
1. Heterocyclic Chemistry Vol. 1-3, RR Gupta, M Kumar and V Gupta, Springer Verlag.
2. The Chemistry of Hetrocycles, T Eicher and S Hauptmann, Thieme.
3. Heterocyclic Chemistry, JA Joule, K Mills and GF Smith, Chapman and Hall.
4. Heterocyclic Chemistry, TLGilchrist, Longman Scientific Techinal.
5. Contemporary Heterocyclic Chemistry, GR Newkome and WW Paudler, Wiley-Inter Science.
6. An Introduction to the Heterocyclic Compounds, R.M. Acheson, John Wiley.
7. Comprehensive Heterocyclic Chemistry, A.R. Katritzky and C.W. Rees, eds. Pergamon Press.
 MSCH413-PRINCIPLES AND APPLICATIONS OF SPECTROSCOPY
Fundamental of Spectroscopy
Electromagnetic radiation, Born-Oppenheimer approximation, types of spectra,
intensity of spectral lines, transition probability, transition moment, natural line
width and natural line broadening and selection rules.
Unit 1 15 HRS
Microwave Spectroscopy:Classification of molecules, rigid and non-rigid rotator
model, effect of isotopic substitution on the transition frequencies and intensities,
stark effect, nuclear and electron spin interaction and effect of external field and
applications.
Infrared Spectroscopy
Review of harmonic oscillator, vibrational energies of diatomic molecules, zero-
point energy, force constant and bond strengths, normal modes of vibration,
anharmonicity, overtones, hot bands, selection rules, group frequencies, Hook’s
Unit 2 law and calculation of frequencies for different types of bonds, factors affecting 15 HRS
bond position and intensities and applications.
Raman spectroscopy:Classical and quantum theories of Raman Effect, pure
rotational, vibrational and vibrational rotational Raman spectra, selection rules,
mutual exclusion principle and applications.
Vibrational Spectroscopy of Polyatomic molecules
Symmetry of normal modes of molecules, infra-red and Raman activity of: Bent
AB2 type molecules and comparision with other C2v molecule like ZAB2, ClF3,
cis-N2F2, cis-PtCl2L2, CH2Cl2, cis-ML2X4 and mer-ML3X3. AB4 type molecules
having tetrahedral, square planar, square pyramidal and see saw shape &
octahedral molecules. 15 HRS
Unit 3
Electronic Spectroscopy: Intensity of vibrational – electronic spectra: frank
codon principle, rotational fine structure of electronic-vibration transitions,
concept of potential energy curve for bonding and antibonding orbital.
Qualitative description of selection of σ, π and non-bonding molecular orbital
their energy level and respective transitions, selection rules for electronic
spectroscopy and chemical analysis by electronic spectroscopy.
Electron Spin Resonance Spectroscopy (ESR)
Basic Principle, ESR Instrumentation, hyperfine splitting, factors affecting the
‘g' Value, Zero Field Splitting, Isotropic and Anisotropic Hyperfine Coupling
15 HRS
Unit 4 Constants, Spin Hamiltonian, Spin Densities and applications.
Nuclear Quadrupole Resonance Spectroscopy (NQR)
Basic principle, effect of magnetic field on spectra, electric field gradient and
molecular structure and applications.
Mossbauer Spectroscopy
Basic principles, spectral parameters and spectrum display. Application of the
technique to the studies of (1) bonding and structure of Fe2+ and Fe3+ compounds
including those of intermediate spin (2) Sn2+ and Sn4+ compounds, nature of
metal ligand bonding, coordination number, structure and (3) detecction of 15 HRS
Unit 5 oxidation state and inequivalet MB atoms.
Photoelectron Spectroscopy: Photo-electric Effect, Ionization Process and
Koopman's Theorem. UV Photoelectron Spectra of atoms and Simple Molecules,
X-ray photoelectron spectra of gases and solids.
Auger electron spectroscopy: Auger electron ejection and its examples.
Suggested Readings:
1. Modern Spectroscopy, J.M. Hollas, John Wiley.
2. Applied Electron Spectroscopy for Chemical Analysis Ed. H. Windawi and F.L. Ho, Wiley
Interscience.
3. NMR, NQR, EPR and Mossbauer Spectroscopy in Inorganic Chemistry, R.V. Parish, Ellis
Harwood.
4. Physical Methods in Chemistry, R.S. Drago, Saunders College.
5. Introduction to Molecular Spectroscopy, G.M. Barrow, McGraw Hill Basic
6. Principles of Spectroscopy. R. Chang, McGraw Hill
7. Theory and Applications of UV Spectroscopy, H.H. Jaffe and M. Orchin, IBH-Oxford.
8. Introduction to Photoelectron Spectroscopy, P.K. Ghosh, John Wiley
9. Introduction to Magnetic Resonance, A. Carrington and A.D. Maclachalan, Harper & Row.
 MSCH 414 (A): ORGANIC SYNTHESIS-II
Disconnection Approach
An introduction to synthons and synthetic equivalents, disconnection
approach, functional group inter-conversions, the importance of the order
Unit 1 15 HRS
of events in organic synthesis, one group C-X and two group C-X
disconnections, chemo selectivity, reversal of polarity, cyclisation
reactions, amine synthesis.
Protecting Groups
Principle of protection of alcohol, amine, carbonyl and carboxyl groups.
Ring Synthesis 15 HRS
Unit 2
Saturated heterocycles, synthesis of 3-, 4-, 5- and 6-membered rings,
aromatic
heterocycles in organic synthesis.
One Group C-C Disconnections
Alcohols and carbonyl compounds, regioselectivity. Alkene synthesis, use 15 HRS
Unit 3
of acetylenes and aliphatic nitro compounds in organic synthesis.

Two Group C-C Disconnections

Diels-Alder reaction, 1,3-difunctionalised compounds, ,-unsaturated
Unit 4 carbonyl compounds, control in carbonyl condensations, 1,5- 15 HRS
difunctionalised compounds.
Micheal addition and Robinson annelation.

GREEN SYNTHESIS: Introduction, basic principles of green chemistry

and their illustrations with examples. Green synthesis of adipic acid, 15 HRS
Unit 5
catechol, 3- dehydroshikimic acid acetaldehyde, ibuprofen and
paracetamol,methyl methacrylate,urethane and marine ani foulant.
Books Suggested:
1. Designing Organic Synthesis, S. Warren, Wiley.
2. Organic Synthesis- Concept, Methods and Starting Materials, J. Fuhrhop and G.
3. Penzillin, Verlage VCH.
4. Some Modern Methods of Organic Synthesis. W. Carruthers, Cambridge Univ.
5. Press.
6. Modern Synthetic Reactions, H.O. House, W.A. Benjamin.
7. Advanced Organic Chemistry: Reactions, Mechanisms and Structure, J. March,
8. Wiley.
9. Principles of Organic Synthesis, R. Norman and J.M. Coxon, Blackie Academic
10. New Trends in Green Chemistry V.K. Ahluwalia, M. Kidwai, Anamaya Publishers
11. Modern Synthetic Reaction, H.O. House, W.A. Benjamin.
12. Some Modern Methods of Organic Synthesis, W.Carruthers, Cambridge university Press
13. Advanced Organic Chemistry, Reaction Mechanisms and Structure, J. March, John Wiley.
14. Organic Synthesis – the Disconnection approach, S.Warren ,Wiley
15. Advanced Organic Chemistry, Part B, F. A. Carey and R.J. Sundberg, Plenum Press
 MSCH414 (B) - NANOSCIENCE
Introduction: Nano scale concept, Nanoparticle and Nanomaterial,
classification
Effect of nanometer length scale: Quantum confinement and surface to
Unit 1 volume ratio. 15 HRS
Unique properties of Nanomaterial Physical properties:
electrical,magnetic,thermal,optical properties and Chemical
properties:Catalyst,M.P,B.P.
Nano synthesis: Concept of Top down and Bottom up
Technique,Chemical method:Chemical vapor deposition(CVD),Reduction 15 HRS
Unit 2
method,Sol-Gel method,sonochemical method.
Physical method:lithography,Sputtering,Aerosol spraying
Nanostructure material:General structure, Preparation and Properties of
nanomaterial: Carbon Nano tubes(CNT), Graphene and Fullerene, 15 HRS
Unit 3
Inorganic metal Nanoparticle of silver and gold, Metal oxide
nanoparticles,Polymeric Nanomaterial.
Characterization Technique: General classification of characterization
technique, Electron Microscopy: Scanning electron microscopy(SEM),
Transmission electron microscopy(TEM)
15 HRS
Unit 4 Scanning Probe Microscope Technique; Atomic force Microscopy(AFM)
Safety and Storage of nanoparticles
Particle size Analyzer; DLS (Dynamic light scattering), X-ray
Diffraction(XRD)
Applications of Nanotechnology in field of Energy: Pharmaceuticals, 15 HRS
Unit 5
Clinical and Healthcare, Security and Environment

Suggested Readings:

1. Willard “Instrumental Methods of Analysis” 2000

2. Charles P.Poole,Jr and Frank J Owens ;Introduction to Nanotechnology, Wiley ,2003
3. Nanostructures materials: Processing, Properties and applications, C. C. Kouch,
William Andrew publications, NewYork, 2002.
4. Introduction to nanotechnology, C. P. Poole Jr, F. J. Owens, 2nd edition, Wiley-India,
Delhi, 2008.
5. Nanostructures and nanomaterials, G. Cao, Imperial College Press, University of
Washington, USA, 2004
6. Nanotechnology Fundamentals and applications, M. Karkare, I. K. Interna
7. Essentials in nanoscience and nanotechnology,N.Kumar and S.Kumbhat,John
Wiley(NY),2016
8. Nanoscale and Technology,Robert Kesall,John Wiley.
9. Nanochemistry, Nishit mathur,RBSA Publisher,2010
10. Harry R lock.Introduction to Material Chemistry,Wiley
MSCH421: LABORATORY COURSE VII: PHYSICAL CHEMISTRY

A. Chemical Kinetics
a. To investigate the kineticsof the reaction between I- and persulphate ion
i. Order of the reaction
ii. Energy of activation of the reaction.
iii. Effect of ionic strength on rate.
b. To find out the order of the reaction of saponification of ester using unequal
concentrations of reactants.
c. To study the reaction between ceric ammonium nitrate and primary alcohol.
B. Conductometry:
a. To find out the equivalent conductance of strong electrolytes at different dilutions
and to verify Debye HuckelOnsagar equation.
b. To determine the equivalent conductance of a weak electrolyte at infinite dilution.
To determine the dissociation constant of acetic acid/Oxalic acid and verify the
Ostwald's dilution law.
c. Determination of the velocity constant, order of the reaction and energy of
activation for saponification of ethyl acetate by NaOHconductometrically.

C. Phase Equilibrium:
a. To find out the equilibrium constant for the triiodide formation.
b. To find the formula of complex cuprmmonium ion by distribution method.
c. To contracture the phase diagram for three component system (e.g.
Chloroform acetic acid-water)

D. Polarimetry
a. To determine the specific rotation of a given optically active compound.

Suggested Readings:
1. Practical Physical Chemistry, A.M. James and F. E. Prichard, Longman.
2. Findley's Practical Physical Chemistry, B.P. Levitt, Longman. Experimental Physical
Chemistry, R.C. Das and B. Behera, Tata McGraw Hill.
3. Advanced Practical Physical Chemistry, J.B. Yadav, Goel Publishing House.
4. Advanced Experimental Chemistry, vol.1, Physical J.N. Gurtu and R. Kapoor, S. Chand & Co.

MSCH422: LABORATORY COURSE VIII: INORGANIC CHEMISTRY

I. Preparations
a. Na3[Fe(C2O4)3]
b. Prussian Blue( Fe4[Fe(CN)6])
c. [Ni(NH3)6] Cl2
d. [Ni(dmg)2]
e. Potassium Chlorochromate
f. Na3[Co(NO2)6]
g. K3[Cr(C2O4)3].3H2O
h. Cis& trans potassium diaquodioxalatochromate(III)
i. Potassium trioxalatochromate(III).
j. Cuprous tetraiodomercurate(II).
k. Tetraamminecarbonatocobalt(III) nitrate.
l. Pentaamminechloridocobalt(III) chloride.
 m. Tris(acetylacetonato)manganese(III) ion

II. Determination of stability constant and composition of complex by Job’s

method. (Iron Thiocyanide & Iron phenanthroline).
III. Analysis of some alloys.

MSCHSC431 (A): BASIC SKILL IN SPECTROSCOPIC ANALYSIS

THEORY:

Electromagnetic radiations and their principle,basics of spetroscopic,absorption and emission , flame

photometry: Basic principal instrumentation and application.

Atomic Absopation spectrocsopy: Basic principle, instrumentation ,types of burners,hollow cathod

lamps, detection and application.

PRACTICALS:

1. Estimation of Na,K,Ca and Li in water and soil sample.

2. Determination of Zn,Cu and Fe etc.in water and soil sample.
3. Determination of common heavy metal ion in biological sample.

Suggested Readings:

1. Vogel's Textbook of Quantitative Chemical Analysis, G.H. Jeffery, J. Bassett, J.

Mendham and R.C. Denney, Publ ELBS, Longman, UK
2. Basic Concepts of Analytical Chemistry, S.M. Khopkar, Wiley Eastern.
3. Fundamentals of Analytical Chemistry, D.A. Skoog, D.M. West and F.J. Holler. Pubi WB
Saunders.
4. Analytical Chemistry, G.D. Christian, John Willy & Sons.