Zio XT Final Report for iRhythm Technologies

Tel: (888) 693-2401

REDACTED www.zioreports.com

Date of Birth Patient ID Gender Primary Indication (R00.2) Enrollment Period Analysis Time
REDACTED(34 yrs) REDACTED Male Palpitations 2 days 21 hours 2 days 21 hours
04/30/19, 03:23pm to (after artifact removed)
Prescribing Clinician Managing Location
REDACTED REDACTED 05/03/19, 12:26pm

Ventricular Tachycardia (4 beats or more) Heart Rate

Overall Max 172 bpm 10:03am, 05/02

Min 41 bpm 03:57am, 05/02

None found
Avg 72 bpm

Sinus Max 172 bpm 10:03am, 05/02

Min 45 bpm 06:20am, 05/03

Avg 73 bpm
Pauses (3 secs or longer)
Patient Events
Triggered Findings within ± 45 sec of Triggers:
None found Events: 14 Sinus Rhythm, Ectopic Atrial
Rhythm, Ventricular Ectopic
beat(s)

AV Block (2nd° Mobitz II, 3rd°) Diary Findings within ± 45 sec of Entries:
Entries: 12 Sinus Rhythm, Ectopic Atrial
Rhythm, Supraventricular Ectopic
beat(s)
None found

Ectopics Rare
<1%
Occasional
1% to <5%
Frequent
5%+
Supraventricular Ectopy (SVE/PACs)
Atrial Fibrillation Isolated Rare <1.0%
Couplet 0
Triplet 0
None found

Ventricular Ectopy (VE/PVCs)

Isolated Rare <1.0%
Couplet 0
Triplet 0

Supraventricular Tachycardia (4 beats or more) None found Longest Ventricular Bigeminy Episode 0s
Longest Ventricular Trigeminy Episode 0s

Preliminary Findings Final Interpretation

Patient had a min HR of 41 bpm, max HR of 172 bpm, and avg HR of 72
bpm. Predominant underlying rhythm was Sinus Rhythm. Ectopic Atrial
Rhythm was present. Ectopic Atrial Rhythm was detected within +/- 45
seconds of symptomatic patient event(s). Isolated SVEs were rare
(<1.0%), and no SVE Couplets or SVE Triplets were present. Isolated VEs
were rare (<1.0%), and no VE Couplets or VE Triplets were present.

SIGNATURE

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 Events

6am noon 6pm midnight 6am noon 6pm

Days 1 & 2

HR per 20 min period:

HR
(bpm) Max/Min Avg

7 Patient diary events

9 Patient triggered
0 PVT, VF, TdP
0 VT
0 SVT
0 Pauses
0 % AF burden
0 AV Block
Unanalyzable ECG

6am noon 6pm midnight 6am noon 6pm

Days 3 & 4

5 Patient diary events

5 Patient triggered
0 PVT, VF, TdP
0 VT
0 SVT
0 Pauses
0 % AF burden
0 AV Block
Unanalyzable ECG

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 Patient
Events

Patient Triggered Events

Note: Triggered Event strips cover 45 seconds before and after the button press.

= Patient Triggered Marker = Vertical Zoom

04/30/19 09:02:23pm Sinus (67 bpm) 2.1x, 90 s

05/01/19 05:47:12am Sinus (62 bpm) 2.6x, 90 s

05/01/19 06:33:46am Sinus (64 bpm), Ectopic Atrial Rhythm (55 bpm) 2.2x, 90 s

05/01/19 08:15:35am Sinus (93 bpm) 2.5x, 90 s

05/01/19 01:13:20pm Sinus (76 bpm) 2.1x, 90 s

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05/01/19 05:32:32pm Sinus (76 bpm) 2.3x, 90 s

05/01/19 06:43:14pm Sinus (84 bpm) 2.5x, 90 s

05/01/19 06:48:57pm Sinus (121 bpm), VE(s) 2.0x, 90 s

05/01/19 07:57:17pm Sinus (70 bpm) 2.1x, 90 s

05/02/19 01:10:11am Sinus (65 bpm) 2.0x, 90 s

05/02/19 01:13:40am Sinus (78 bpm) 2.1x, 90 s

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05/02/19 04:27:22pm Sinus (87 bpm) 2.6x, 90 s

05/02/19 04:30:43pm Sinus (102 bpm) 2.0x, 90 s

05/03/19 09:14:22am Sinus (60 bpm), Ectopic Atrial Rhythm (58 bpm), Artifact 1.0x, 90 s

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Patient Diary Entries
Notes: iRhythm cannot verify the accuracy of the patient-reported information provided below.

Patient Diary strips cover 45 seconds before and after the patient's stated diary entry time.

= Patient Triggered Markers captured within the Patient Diary ECG = Vertical Zoom

Date Time Symptoms Duration Activity

04/30/19 09:00pm pain/tingling (in neck or arm) between 1 and 10 mins playing
Findings: Sinus (69 bpm) 2.2x, 90 s

Date Time Symptoms Duration Activity

05/01/19 06:00am fluttering/racing between 1 and 10 mins lying in bed

Findings: Sinus (55 bpm) 4.0x, 90 s

Date Time Symptoms Duration Activity

05/01/19 06:15am fluttering/racing between 1 and 10 mins in bed

Findings: Sinus (55 bpm), Ectopic Atrial Rhythm (53 bpm) 2.4x, 90 s

Date Time Symptoms Duration Activity

05/01/19 08:15am no symptoms

Findings: Sinus (95 bpm) 2.5x, 90 s

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Date Time Symptoms Duration Activity

05/01/19 01:15pm fluttering/racing between 1 and 10 mins In a meeting

Findings: Sinus (76 bpm) 2.6x, 90 s

Date Time Symptoms Duration Activity

05/01/19 05:30pm fluttering/racing between 1 and 10 mins

Findings: Sinus (81 bpm) 2.7x, 90 s

Date Time Symptoms Duration Activity

05/01/19 06:45pm fluttering/racing

Findings: Sinus (102 bpm) 2.4x, 90 s

Date Time Symptoms Duration Activity

05/02/19 01:15am fluttering/racing, pain/tingling (in between 1 and 10 mins

neck or arm), anxious
Findings: Sinus (83 bpm) 1.3x, 90 s

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Date Time Symptoms Duration Activity

05/02/19 01:18am fluttering/racing, pain/tingling (in between 1 and 10 mins lying down
neck or arm), anxious
Findings: Sinus (60 bpm) 4.0x, 90 s

Date Time Symptoms Duration Activity

05/02/19 04:30pm lightheaded, dizziness, anxious between 1 and 10 mins

Findings: Sinus (91 bpm) 2.0x, 90 s

Date Time Symptoms Duration Activity

05/02/19 04:35pm fluttering/racing, lightheaded between 1 and 10 mins

Findings: Sinus (101 bpm), SVE(s) 2.0x, 90 s

Date Time Symptoms Duration Activity

05/03/19 08:50am fluttering/racing, pounding between 1 and 10 mins

Findings: Sinus (57 bpm) 2.5x, 90 s

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 Additional
Strips

Minimum Heart Rate (41 bpm), Sinus, Ectopic Atrial Rhythm

1 05/02/19 03:57:35am

Minimum Sinus Rate (45 bpm)

2 05/03/19 06:20:51am

Maximum Sinus Rate (172 bpm)

3 05/02/19 10:03:43am

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 Sinus (154 bpm)
4 05/02/19 10:03:04am

Sinus (148 bpm)

5 05/02/19 10:04:11am

Sinus (56 bpm), SVE(s)

6 05/01/19 03:19:26am

Sinus (57 bpm), Ectopic Atrial Rhythm (53 bpm)

7 05/01/19 06:14:43am Associated with patient diary event (accuracy of times reported by
patient cannot be guaranteed)

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 Sinus Arrhythmia (66-110 bpm)
8 05/01/19 08:15:17am Associated with patient triggered/diary event

Sinus (101 bpm), VE(s), Non-Conducted SVE(s)

9 05/01/19 06:49:23pm Associated with patient triggered event

Sinus (72 bpm), VE(s)

10 05/02/19 12:31:05am

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Report Version: 4.1.1-1, 05/07/19 10:57:30