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Enzyme Classification: Class Type of Reaction Catalyzed Example of Enzymes

The document discusses the classification of enzymes. There are six main classes of enzymes defined by the type of chemical reaction they catalyze: oxidoreductases catalyze oxidation-reduction reactions; transferases transfer functional groups; hydrolases catalyze hydrolysis reactions; lyases remove or add groups without hydrolysis; isomerases rearrange atoms within molecules; and ligases join two molecules together using ATP. The classification system was introduced in 1961 by the International Union of Biochemistry and provides examples of enzymes in each class.

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Alees Rahaizan
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71 views

Enzyme Classification: Class Type of Reaction Catalyzed Example of Enzymes

The document discusses the classification of enzymes. There are six main classes of enzymes defined by the type of chemical reaction they catalyze: oxidoreductases catalyze oxidation-reduction reactions; transferases transfer functional groups; hydrolases catalyze hydrolysis reactions; lyases remove or add groups without hydrolysis; isomerases rearrange atoms within molecules; and ligases join two molecules together using ATP. The classification system was introduced in 1961 by the International Union of Biochemistry and provides examples of enzymes in each class.

Uploaded by

Alees Rahaizan
Copyright
© © All Rights Reserved
Available Formats
Download as PDF, TXT or read online on Scribd
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2/28/2019

Enzyme Classification
Naming of enzyme: • Enzymes can be classified
• Randomly at the time of
discovery: such as by the chemical reaction
digestive enzymes. catalyzed.
• Six classes of enzyme.
• Enzyme names indicate
both the substrate
acted upon and the type of • This classification system
reaction catalyzed.
introduced in 1961 by IUB
• By adding the word – ase (International Union of
to the root of the name of Biochemistry).
the substrate, such as
urease, which acts on urea.

CLASS TYPE OF REACTION CATALYZED EXAMPLE OF ENZYMES

1. Oxidoreductase Involve in oxidation-reduction. Dehydrogenase


Removal H atom from substrate
- Transfer of H and O atoms or
electrons from one substances Oxidase
to another. Addition of O to H with the formation of water

Ex: Cyctochrome oxidase, Lactate dehydrogenase

2. Transferase Transfer of functional groups Transaminase kinase


from one substance to another Glycogen Phosphorylase

- amino group, acetyl group,


phosphate group or methyl
group.

3. Hydrolase Formation of two products from Lipase


a substrate by hydrolysis Amylase
(addition of water) Peptidase

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2/28/2019

CLASS TYPE OF REACTION CATALYZED EXAMPLE OF ENZYMES

4. Lyase Removal or addition of groups Decarboxylase (removal of CO2)


of atoms without hydrolysis Carboxylase (addition of CO2)

5. Isomerase Rearrangement of atoms within Isomerase


a molecule. Mutase

-Intramolecules rearrangement

6. Ligase Join together two molecules by Acetyl-Co A synthetase


with simultaneous breakdown Phosphofructo kinase
of ATP. DNA ligase

Q & A?

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