Cip / Sip: IWI E
Cip / Sip: IWI E
CIP / SIP
Industrial EquipWash Inc has over two decades of Designs and Configurations
experience in the design, fabrication, installation IEWI offers several designs of CIP system. The
and start-up of CIP & SIP systems for the pharma, “single-pass” and the “recirculating” configuration
bio- pharma, dairy, food and other processing are often utilized in the processing industries, since
industries. Clean-in-place (CIP) & Steam-in-place both require minimal capital investment, typically
( SIP) technology offers significant advantages to have a small footprint and are flexible, in that the
manufacturing facillities, for effiecient and reliable unit can readily adjust to a range of cleaning
cleaning of process equipment and pipping at protocols. However, the cost for the chemicals,
lower cost to improved product quality. CIP water & steam and for disposal of waste water
technology involves the use of chmicals, sterilents, are higher than for other designs.
high pressure pumps, spray nozzles and spray
balls and aseptic design principles to ensure that The “ re-used design” provides for the recycling of
large scale process are free of dirt, organic the water and possible regeneration of the cleaning
contaminants and micro-organisms. chemicals. These CIP systems have “single-pass”
systems and there is a greater risk of cross-
Benefits of CIP contamination during operation. The “re-use”systems
also lack flexibility, in that a single temperature and
The development of CIP and SIP technology , i.e., single concentration of cleaning solution is used
the automatic, reproducible and reliable delivery for whole process systems, unless additional vessels
of cleaning solutions, rinse and wash water to and are included in the CIP unit. The pharma and
through process equipment and process piping, bio-pharma industries prefer to use a “multi-tank”
has improved both product quality and plant hygiene. configuration, with independent, stainless steel tanks
Furthermore, the ability to clean a processing system,
being used to hold water of different quality, e.g.,
incorporating tanks, pumps, valves, filters, heat
Deionized water (DI), hot or cold water for injection
exchange units and process piping, without the need
(WFI) and water from reverse osmosis units (RO).
to disassembled all or part of that system, significantly
reduces cleaning costs and minimizes the handling of
These multi-tank systems are operated as if they were
chemicals to provide a safer environment for plant single-use systems, the tanks being drained between
personnel. These systems may be integrated into existing subsequent programs to minimize cross-contamination.
processing systems, but more importantly, clean-in
place technology should be included in the design
of any new process systems, to be simultaneously
incorporated with the design of the process flows, Washing Cyclic Operation
the controls and automation.
The washing process consists of the following
sequence: Wash down rinse, Acid wash ,
Alkaline wash, Wash down, Final wash.
LE
RTD
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TR
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D
IF
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UG
A
RA
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PU
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M
M
P
V
A
LV
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IEWI
PS PG-2 PS
NRV AIR FILTER
STEAM INLET AIR INLET
FDV-4 TO USER
FDV-5 FDV-6
FDV-3
PS
S.G./L.G.
HOSE PIPE
PS
V1
ؽ”
FILTER
S.G./L.G.
DV-2
0.22µ
ؽ”
SV SV V2
DV-1
R Y B
TOUCH SCREEN
MIMIC
FDV-9
DP1 DP2 PS FORWARD PS REVERSE
PUMP-P1 RTD-3
PUMP-P2
FDV-2 FDV-8 FDV-7
RTD1
RTD-2 GV-2 GV-1
ALKALI ACID
FDV-1
ST-1
FDV-10 GV-3
TROLLEY
DRAIN-1 DRAIN-2 DRAIN-3
LEGEND
BV-8
FLEXIBLE HOSE
BV-7
BV-6
CS. 1
BV-2 BV-3 BV-4
BV-5
LT.
Ø 1 / 2"
Ø 1 / 2"
FLOOR
PG. 2
SPRAY BALL
INSULATED RO WATER
STORAGE TANK
DP1 PG. 1 FLEXIBLE HOSE
150 Ltrs.
DP2
HEATER BV-12
ALKALI BV-9 ST.
RTD-2
FORWARD PUMP-P1
REVERSE PUMP-P2
L E G E N D
µ = MICRON
ST = STEAM TRAP
DV = DIAPHRAGM VALVE DP1 = DOSING PUMP 1 ( ALKALI )
PG = PRESSURE GAUGE
BV-1&BV-13 = BUTTER FLY VALVE WITH ACTUATOR LT LEVEL TRANSMITTER DP2 = DOSING PUMP 1 ( ACID)
=
SIGHT AND LIGHT GLASS CS = CONDUCTIVITY SENSOR SV = SAFETY VALVE
SG/LG = CA = COMPRESSED AIR
NRV = NON RETURN VALVE ST = STEAM TRAP PS = PURE STEAM RTD = TEMP. SENSOR
SLAB
PENDENT
PANEL
BALL VALE
S
Solenoid Valve T
A
N
PG. Regulator
D
SS. Braided Teflon Hose
PVC Hose Tray
zl e s
No z
Nozzles
RTD.
SIP SKID