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Bone Marrow Failure States

Bone marrow failure states refer to conditions where the bone marrow is unable to produce sufficient new blood cells. These include aplastic anemia, myelodysplastic syndromes, pure red cell aplasia, myelophthisis, and pancytopenia. Clinical features include abrupt or insidious bleeding, weakness, shortness of breath, and infections due to low blood cell counts. Treatment options are bone marrow transplant, immunosuppression therapy, and supportive care. Myelodysplastic syndromes differ from aplastic anemia in that patients may also experience constitutional symptoms and have a higher risk of developing acute myeloid leukemia.

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Bea Samonte
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75 views2 pages

Bone Marrow Failure States

Bone marrow failure states refer to conditions where the bone marrow is unable to produce sufficient new blood cells. These include aplastic anemia, myelodysplastic syndromes, pure red cell aplasia, myelophthisis, and pancytopenia. Clinical features include abrupt or insidious bleeding, weakness, shortness of breath, and infections due to low blood cell counts. Treatment options are bone marrow transplant, immunosuppression therapy, and supportive care. Myelodysplastic syndromes differ from aplastic anemia in that patients may also experience constitutional symptoms and have a higher risk of developing acute myeloid leukemia.

Uploaded by

Bea Samonte
Copyright
© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
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Download as PDF, TXT or read online on Scribd
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MEDICINE
1.4C BONE MARRIW FAILURE STATES

BONE MARROW FAILURE STATES


Myelodysplastic Syndrome
Aplastic Anemia
Pure Red Cell Aplasia
Myelophthisis
Pancytopenia
Deficient hematopoiesis

CLINICAL FEATURES
Abrupt or insidious
Bleeding
Lassitude
Weakness
Shortness of Breath
Infections
No other Constitutional Symptoms
Pancytopenia
Low Reticulocyte Count

TREATMENT
Bone Marrow Transplant
Immunosuppression
Supportive Care

APLASTIC ANEMIA

MYELODYSPLASTIC SYNDROMES

CLINICAL FEATURES
Abrupt or insidious
Bleeding
Lassitude
Weakness
Shortness of Breath
Infections
Constitutional Symptoms
Cytopenias
Low Reticulocyte Count
Higher Risk of Developing AML

BEI SAMONTE Page 1 of 2

Medicine

1.4C BONE MARRIW FAILURE STATES

BLASTS

TREATMENT
Bone Marrow Transplant
Demethylating Agents
Lenalidomide
Supportive Care

__________________________________________________________
END OF TRANX

BEI SAMONTE Page 2 of 2

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