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MCB 160 Syllabus

This document outlines the course details and schedule for MCB 160: Cellular & Molecular Neurobiology at UC Berkeley in Fall 2015. The course will be taught on Mondays, Wednesdays, and Fridays from 11-12pm in 145 Dwinelle Hall. It will be taught by three professors - Dr. Richard Kramer, Dr. Helen Bateup, and Dr. John Ngai. The schedule lists the dates and topics to be covered in each of the 38 lectures. Topics include neural signals, synapses, neural plasticity, sensory transduction, neural development, and diseases of the nervous system. There will be two midterm exams and a final exam from 11:30am-2:

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mrdead
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325 views

MCB 160 Syllabus

This document outlines the course details and schedule for MCB 160: Cellular & Molecular Neurobiology at UC Berkeley in Fall 2015. The course will be taught on Mondays, Wednesdays, and Fridays from 11-12pm in 145 Dwinelle Hall. It will be taught by three professors - Dr. Richard Kramer, Dr. Helen Bateup, and Dr. John Ngai. The schedule lists the dates and topics to be covered in each of the 38 lectures. Topics include neural signals, synapses, neural plasticity, sensory transduction, neural development, and diseases of the nervous system. There will be two midterm exams and a final exam from 11:30am-2:

Uploaded by

mrdead
Copyright
© © All Rights Reserved
Available Formats
Download as PDF, TXT or read online on Scribd
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Fall,

2015 MCB 160: Cellular & Molecular Neurobiology


MWF, 11-12 145 Dwinelle Hall

Course Professors:
Dr. Richard Kramer (RK) (course director)
[email protected]
Dr. Helen Bateup (HB)



[email protected]
Dr. John Ngai (JN)



[email protected]

Lect Prof Date
THEME and topic

1
2
3
4
5



RK
RK
RK
RK
RK


6
7
8
9


RK
RK
RK
RK



W Aug 26
F Aug 28
M Aug 31
W Sep 2
F Sep 4
M Sep 7
W Sep 9
F Sep 11
M Sep 14
W Sep 16



10
11
12
13
14



RK
RK
RK
HB
HB



F Sep 18
M Sep 21
W Sep 23
F Sep 25
M Sep 28




15
16




HB
HB

F Oct 2
M Oct 5

17

HB

W Oct 7

18
19

HB
HB

F Oct 9
M Oct 12


Dendrites and dendritic spines
Optical methods in neurobiology
Cellular basis of learning and memory
// Intro to neural plasticity
Hebbian synaptic plasticity: LTP
LTD, STDP, and structural synaptic plasticity



20
21
22


HB
HB
HB


W Oct 14
F Oct 16
M Oct 19


DISEASES OF THE NERVOUS
SYSTEM
Neurodevelopmental disorders and epilepsy
Neurodegenerative disorders
Psychiatric disorders

30
W Sep


INTRODUCTION TO NEURAL SIGNALS
Introduction to the nervous system
Recording neural activity
Passive electrical properties of neurons
Origin of the membrane potential
Selective permeability of ion channels
Labor Day
Gating of ion channels
The action potential
Propagation of action potentials
Spontaneous activity and oscillations

SYNAPSES
Synaptic transmission (presynaptic function)
Synaptic transmission (NMJ postsynaptic function)
Synaptic excitation, inhibition, and integration
Neurotransmitters
Neuromodulators/GPCR signaling

MIDTERM
1


Chapter


Chapters 1 and 2
Chapters 1 and 2
Chapter 5 + Appendix A
Chapter 6
Chapter 5

Chapter 5
Chapter 7
Chapter 7



Chapter 12
Chapter 9
Chapter 10
Chapter 13
Chapter 11


p228-234 + p 1210-1213

Chapter 67
Chapter 67
Chapter 67

Chapters 50 a nd 64
Chapter 44
Chapters 62 and 63



23
24
25
26
27
28


JN
JN
JN
JN
JN
RK





29
30





JN
JN


31
32
33
34
35


JN
JN
HB
JN
JN



36
37
38


JN
JN
JN

W Oct 21
F Oct 23
M Oct 26
W Oct 28
F Oct 30
M Nov 2
4
W Nov

F Nov 6
M Nov 9
W Nov 11
F Nov 13
M Nov 16
W Nov 18
F Nov 20
M Nov 23
W Nov 25
F Nov 27
M Nov 30
W Dec 2
F Dec 4
14
M Dec

SENSORY TRANSDUCTION
Hair cells and mechanotransduction
Phototransduction 1
Phototransduction 2
Olfactory and taste transduction
Pain and temperature transduction
Circadian rhythms and light entrainment

MIDTERM
2
NEURAL DEVELOPMENT
Early neural induction
Specification of regional identity
Veterans Day
Specification of cell fates I
Specification of cell fates II
Regeneration and adult neurogenesis
Trophic factors and cell death
Axon guidance I
Non-instructional day
Thanksgiving holiday
Axon guidance II & Synapse formation I
Synapse formation II
Activity-dependent synaptic refinement
FINAL EXAM: 11:30 - 2:30

Chapter 30
Chapter 26
Chapter 26
Chapter 32
Chapter 24





Chapter
52
Chapter 52

Chapter
53
Chapter 53
Chapter 57
Chapter 53
Chapter 54

Chapters 54 and 55
Chapter 55
Chapter 56

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