Question 1

Medium chain triglycerides are used in the formulation of dietary aids because >>I. they
are more rapidly absorbed than long chain fats. >>II. they are the usual form of animal
fats. >>III. they provide more calories, per gram, than long chain fats.
A
I only
B
III Only
C
I and II only
D
II and III only
E
All the above
Question 2
Which Of The Following NOT Used In Peptic Ulcer
A
Tetracycline
B
Metronidazole
C
Itraconazole
D
Bismuth subsalicylate
E
Clarithromycin
Question 3
Patient using anticholinergic drug, will have which of the following side effects?
>>I. Decreased tolerance to heat.
>>II. Decreased sweating.
>>III. Increased IOP.
A
I only
B
III only
C
I and II only
D
II and III only
E
All the above
Question 4
All the following are side effect of oral contraceptive EXCEPT:-
A
Hypertension
B
Weight gain
C
Constipation
D
Hyperglycemia
E
Dizziness
Question 5
Which of the following is the antidote for the toxin Benzodiazepines?
A
Flumazenil
B
Methylene blue
C
Deferoxamine
D
Alkalinize urine
Question 6
Which of the following is NOT abortificient?
A
Misoprostol
B
Carboprost
C
Latanoprost
D
Dinoprostone
E
None
Question 7
Lansoprazole is not used in which of the following cases?
A
Gastritis
B
Peptic Ulcers
C
Zollinger-Ellison syndrome
D
Thalamus hypertrophy
Question 8
Which Cytochrome P450 isozyme does not participateappreciably in drug metabolism?
A
CYP1A2
B
CYP2C9
C
CYP3A4
D
CYP51
E
All are drug metabolizing isoforms
Question 9
What is FALSE with regards to innate immunity?
A
It is a specific immunity
B
It has instant action & is the first line of defense
C
It is nonantigen specific
D
It has no memory
E
None of the above
Question 10
Given F = .24, what is the overall hepatic clearance of morphineif the above patient has
portal hypertension such that theirhepatic blood flow is reduced by ? Assume
the clearancevalue given in the previous question is entirely hepaticclearance.
A
30 L/hr/70 Kg
B
60 L/hr/70 Kg
C
120 L/hr/70 Kg
D
250 L/hr/70 Kg
Question 11
In digoxin induced arrythmia , what is not recommonded?
A
stop digixin administration
B
Phenytoin administration
C
give lidocaine
D
give digoxin immune fab
E
Electrical cardio
Question 12
Which of these clotting factors is found in the extrinsic clotting system?
A
Factor I
B
Factor II
C
Factor VII
D
Factor IX
E
Factor X
Question 13
Benzoil not soluble in H2O but soluble in benzene in 25 c
A
Polar
B
Non polar
C
Soluble
D
Insoluble
E
Slightly polar
Question 14
With regards to COMT inhibitors with of the following are true?
>>I. Tolcapone is a central & peripheral inhibitor.
>>II. Tolcapone can cause liver toxicity and rabhdomyolysis.
>>III. Entacapone acts only peripherally.
A
I only
B
III only
C
I and II only
D
II and III only
E
All thevabove
Question 15
Which area is responsible for initiating, sequencing, modulating motor activity?
A
Basal ganglia
B
Extrapiramidal system
C
Substantia nigra
D
A & B
E
A, B, C
Question 16
Which one of the following agents may be added to local injection of Xylocaine in order to
prolong its effect
A
Succinylcholine chloride
B
Sodium carbxymethylcellulose
C
Polyethylene glycol
D
Epinephrine
Question 17
In a zero order elimination process, which of thefollowing is true?
A
The removal of drug is independent of drug concentration
B
Cl =Elimination rate/Cp
C
t1/2 =.7VD/Cl
D
All are true
Question 18
The drug of choice to control pain during acute myocardial infarction is :
A
Naloxone
B
Bethidine
C
Morphine
D
Celecoxib
E
Naproxen
Question 19
Kernicterus is a drug-induced disorder that may occur in neonates treated with
A
isoniazid
B
sulfisoxazole
C
phenytoin
D
gentamicin
E
promethazine
Question 20
Which of the following enzymes could directly act oncodeine?
A
Glucuronyl transferase
B
Sulfotransferase
C
Glutathione transferase
D
a & b
E
All of the above
Question 21
A 4 mg dose of lorazepam administered to a adult will act as :
A
analgesic
B
Hypnotic
C
antiulcerant
D
Diuretic
E
Antihistaminic
Question 22
Pyridoxine requirements may increase during administration of all the following EXCEPT:
A
Isoniazid
B
Cycloserine
C
Oral contraceptives
D
Levodopa
Question 23
The antiarrhythmic action of tocainide(Tono card) and mexiletine(Mexitil) most closely
resembles that of
A
Acebutolol
B
Verapamil
C
Quinidine
D
Lidocaine
E
Disopyramide
Question 24
Dipivefrin (proppine) can best be described as a(an)
A
Sholinesterase inhibitor
B
Osmotic diuretic
C
Beta- adrenergic blocking agent
D
Prodrug
E
Chelating agent
Question 25
which of the following are characteristic for Erythroped
A
Not effective against G +ve cocci
B
Has amino glycoside antibiotic
C
Can increase GIT motility
D
Can not used in pregnant women if needed
E
None of the above
Question 26
What is a major contraindication to the use of an OTC sympathomimetic drug:
A
gastric ulcer
B
uncontrolled hypotension
C
severe asthma
D
rheumatoid arthritis
E
Hypertension
Question 27
Which of following drugs is the drug of choice for the treatment of all forms of
Schistosomiasis?
A
Praziquantel
B
Mebendazole
C
Niclosamide
D
Thiabendazole
Question 28
A solution is made by dissolving 17.52 g of NaCl exactly 2000 ml. What is the molarity of
this solution?
A
3.33
B
0.15
C
1.60
D
3.00
E
1.6 x 10^-4
Question 29
Which of the following is the antidote for the toxin Lead?
A
Naloxone
B
Nitrite
C
CaEDTA
D
Dialysis
Question 30
Which of the following drugs is the drug may cause discolouration of nail beds and mucus
membranes?
A
Tetracycline
B
Chloroquine
C
Doxycycline
D
Rifampicin
Question 31
Given that the VD = 230 L/70Kg and Cl = 60 L/hr/70Kg for morphine, approximately how
much of a 10 mgIV dose remains after 8 hr, given to a normal 70 Kgpatient?
A
5 mg
B
2.5 mg
C
1.25 mg
D
625 mg
Question 32
A person who always has a belief that is not based on fact or reality, and is extremely
anxious, aggressive and argumentative is classified as which type of schizophrenia?
A
Catatonic
B
Disorganized
C
Paranoid
D
Residual
E
Undifferentiated
Question 33
Enixoparin is administrated:-
A
I.M
B
I.V
C
S.C
D
I.V infusion
Question 34
Which of the following statement is (are) true of epinephrine? >>l. May be administered by
inhalation. >>ll. Reduces arterial blood pressure. >>lll. Peripheral vasodilator
A
I only
B
III only
C
I And II only
D
II and III only
E
All the above
Question 35
which of the following are characteristic for Erythrosine:
A
Not effective against G+ve cocci
B
has amino glycoside antibiotic
C
Decrease GIT motility
D
Should not be used in pregnant woman if need
E
Could be used in pregnant woman if need
Question 36
Which of the following is true about Penicillin V ?
A
It is inactivated by gastric acid
B
It is acid stable
C
It is more active than Benzylpencillin
D
It is absorbed better after foods
Question 37
Which of the following is the primary site of activity for the drug Warfarin?
A
Kidney
B
Liver
C
Blood
D
Heart
Question 38
The EPS that occur after weeks to months of antipsychotic therapy are
>>I. Acute dystonia.
>>II. Akathesia.
>>III.Pseudo Parkinsonism.
A
I only
B
III only
C
I and II only
D
II and III only
E
All the above
Question 39
Which of the following drugs can be used for the treatment of influenza A infection ?
A
Zidovudine(AZT)
B
Amantadine
C
Ribavarin
D
Vidarabine
Question 40
which of the following are characteristic for Erythrosine:
A
Not effective against G+ve cocci
B
has amino glycoside antibiotic
C
Decrease GIT motility
D
Should not be used in pregnant woman if need
E
Could be used in pregnant woman if need
Question 41
Which of the following NT modulates Dopamine activity?
A
5 HT
B
NE
C
GABA
D
Epinephrine
E
Glutamine
Question 42
The above condition can be treated by
>>I. Stopping the antipsychotic.
>>II. Drug therapy with dantrolene or bromocriptine.
>>III.Providing supportive measures
A
I only
B
III only
C
I and II only
D
II and III only
E
All the above
Question 43
Which of the following Cytochrome P450 isozymes isresponsible for the bulk of phase I
metabolism?
A
CYP1A2
B
CYP2C9
C
CYP2D6
D
CYP3A4
E
CYP51
Question 44
How much of a 10 mg dose of morphine reaches thesystemic circulation given F = .24?
A
24 mg
B
0.24 mg
C
2.4 mg
D
4.1 mg
Question 45
Which of the following statement are (is) TRUE of ticlopidine HCI(Ticlid)? >>1. Only
administered parenterally. >>11. Dissolves blood clots. >>111. Inhibits platelet aggregation
A
I only
B
III only
C
I and II only
D
II and III only
E
All the above
Question 46
Sexually transmitted diseases characterized by vaginal discharge are
A
Trichomoniasis caused by trichomonas vaginalis
B
bacterial vaginosis caused by gardnerella vaginalis
C
Vulvovaginal candidiasis caused by Candida albicans
D
only b & c
E
a, b,c
Question 47
Phentolamine is used in the management of
A
status epilepticus
B
cerebral edema
C
pheochromocytoma
D
Cushing's Disease
E
hemorrhage
Question 48
For the majority of drugs, which of the followingequations correctly defines clearance?or
the majority of drugs, which of the followingequations correctly defines clearance?
A
Cl =Elimination rate/Cp
B
Cl =QxE
C
Cl =.7VD/t1/2
D
All are correct
Question 49
Bioavailability is related to which of the followingparameters, according to the equation F
= 1 - E
A
Excretion
B
Elimination
C
Extraction Ratio
D
Enterohepatic Recycling
Question 50
For highly polar drugs (e.g. mannitol) what primarilydetermines elimination rate?
A
Excretion rate
B
Metabolism rate
C
Absorption rate
D
Distribution rate
E
All of the above