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Celebrex: Uses, Dosage, and Precautions

Celebrex is an anti-inflammatory analgesic used to treat osteoarthritis, rheumatoid arthritis, post-surgical or dental pain, and acute pain. It works by inhibiting cyclooxygenase-2 to reduce inflammation, pain, and fever. Common dosages are 200mg once or twice daily for osteoarthritis and 100-200mg twice daily for rheumatoid arthritis. Nurses should educate patients about potential side effects like GI issues and allergic reactions and instruct them to report signs of bleeding, rash, swelling or weight gain.

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981 views2 pages

Celebrex: Uses, Dosage, and Precautions

Celebrex is an anti-inflammatory analgesic used to treat osteoarthritis, rheumatoid arthritis, post-surgical or dental pain, and acute pain. It works by inhibiting cyclooxygenase-2 to reduce inflammation, pain, and fever. Common dosages are 200mg once or twice daily for osteoarthritis and 100-200mg twice daily for rheumatoid arthritis. Nurses should educate patients about potential side effects like GI issues and allergic reactions and instruct them to report signs of bleeding, rash, swelling or weight gain.

Uploaded by

ianecunar
Copyright
© Attribution Non-Commercial (BY-NC)
We take content rights seriously. If you suspect this is your content, claim it here.
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Download as DOC, PDF, TXT or read online on Scribd

Brand Name: Celebrex

Generic Name: Celecoxib


Indications: Acute or chronic use in the treatment of the sings and symptoms of
osteoarthritis and RA. Management and treatment of post-surgical or dental
pain, acute pain and primary dysmenorrhea.
Drug Classification: Antirheumatic, Anti-inflammatory Analgesic
Mechanism of Action: Thought to inhibit prostaglandin synthesis, impeding
cyclooxygenase-2 to produce anti-inflammatory, analgesic, and anti-pyretic
effects.
Dosage: Oseoarthritis Adult 200mg as a single dose or a 2 divided doses. RA 100-200 mg
bid. post-surgical or dental pain, acute flare pain of osteoarthritis 200mg od or
bid.
Special Precaution: Asthma, urticaria or acute rhinitis. Children <18y/o, pregnancy,
lactation, severe hepatic impairment.
Pregnancy Risk: C, D in 3rd trimester
Adverse Reaction: GI complaints, dizziness, bronchitis, coughing, pharyngitis, rhinitis,
sinusitis, upper resp tract infection, headache, accidental injury, flu-like
symptoms, peripheral edema.
Contraindications: Hypersensitivity to drugs, severe hepatic impairment, 3rd trimester of
pregnancy.
Form: Capsules 200 and 300mg
Nursing Responsibilities:
 Tell patient to report history of allergic reactions to sulfonamides, aspirin,
NSAID’s.
 Instruct patient to report signs of GI bleeding.
 Advice patient to immediately report rash, unexplaines weight gain, or swelling.
 Inform patient that it may take several days before he feels consistent pain relief.

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