Safety Data Sheet
1,4-Butanediol
Revision date : 2012/02/27 Version: 1.0 Page: 1/8 (30041337/SDS_GEN_US/EN)
1. Product and Company Identification
Company BASF CORPORATION 100 Campus Drive Florham Park, NJ 07932, USA 24 Hour Emergency Response Information CHEMTREC: 1-800-424-9300 BASF HOTLINE: 1-800-832-HELP
Molecular formula: Chemical family: Synonyms:
HOCH(2)CH(2)CH(2)CH(2)OH
diols
1,4-Butanediol
2. Hazards Identification
Emergency overview CAUTION: MAY BE HARMFUL IF SWALLOWED. MAY CAUSE EYE, SKIN AND RESPIRATORY TRACT IRRITATION. CAN CAUSE KIDNEY DAMAGE. INGESTION MAY CAUSE GASTRIC DISTURBANCES. High concentrations in the air may cause narcosis. Avoid contact with the skin, eyes and clothing. Avoid inhalation of mists/vapours. Use with local exhaust ventilation. Wear a NIOSH-certified (or equivalent) organic vapour respirator. Wear NIOSH-certified chemical goggles. Wear chemical resistant protective gloves. Wear protective clothing. Eye wash fountains and safety showers must be easily accessible.
State of matter: liquid Colour: colourless Odour: almost odourless Potential health effects Primary routes of exposure: Routes of entry for solids and liquids include eye and skin contact, ingestion and inhalation. Routes of entry for gases include inhalation and eye contact. Skin contact may be a route of entry for liquified gases. Acute toxicity: Of moderate toxicity after single ingestion. Virtually nontoxic after a single skin contact. Virtually nontoxic by inhalation. Irritation / corrosion:
Safety Data Sheet
1,4-Butanediol
Revision date : 2012/02/27 Version: 1.0
Not irritating to the skin. Not irritating to the eyes. Assessment other acute effects: Possible narcotic effects (drowsiness or dizziness). Sensitization: Skin sensitizing effects were not observed in animal studies. The substance did not cause skin sensitization in humans. Chronic toxicity: Carcinogenicity: The product has not been tested. The statement has been derived from products of a similar structure or composition. In long-term animal studies in which the substance was given by gavage in high doses, a carcinogenic effect was not observed. Repeated dose toxicity: The substance may cause damage to the liver after repeated ingestion of high doses, as shown in animal studies. Reproductive toxicity: The results of animal studies gave no indication of a fertility impairing effect. The results were determined in a Screening test (OECD 421/422).
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Teratogenicity: Animal studies gave no indication of a developmental toxic effect at doses that were not toxic to the parental animals. The product has not been fully tested. The statements have been derived in parts from products of a similar structure or composition.
Genotoxicity: The substance was not mutagenic in bacteria. The substance was not mutagenic in mammalian cell culture. Medical conditions aggravated by overexposure: Data available do not indicate that there are medical conditions that are generally recognized as being aggravated by exposure to this substance/product. See MSDS section 11 - Toxicological information. Signs and symptoms of overexposure: Overexposure may cause:, unconsciousness, lethargy Potential environmental effects Aquatic toxicity: There is a high probability that the product is not acutely harmful to aquatic organisms. The inhibition of the degradation activity of activated sludge is not anticipated when introduced to biological treatment plants in appropriate low concentrations. Terrestrial toxicity: Study scientifically not justified.
3. Composition / Information on Ingredients
CAS Number 110-63-4 Content (W/W) >= 99.5 % Chemical name 1,4-Butanediol
4. First-Aid Measures
General advice: Remove contaminated clothing. If inhaled: Remove the affected individual into fresh air and keep the person calm. Assist in breathing if necessary. Seek medical attention if necessary.
Safety Data Sheet
1,4-Butanediol
Revision date : 2012/02/27 Version: 1.0 Page: 3/8 (30041337/SDS_GEN_US/EN)
If on skin: Wash affected areas thoroughly with soap and water. Remove contaminated clothing. Wash soiled clothing immediately. If irritation develops, seek medical attention. If in eyes: Wash affected eyes for at least 15 minutes under running water with eyelids held open. If irritation develops, seek medical attention. If swallowed: Rinse mouth and then drink plenty of water. Induce vomiting. Never induce vomiting or give anything by mouth if the victim is unconscious or having convulsions. Immediate medical attention required. Note to physician Treatment:
Treat according to symptoms (decontamination, vital functions), no known specific antidote.
5. Fire-Fighting Measures
Flash point: Autoignition: Lower explosion limit: Upper explosion limit: Flammability: Self-ignition temperature: 115 C 385 C 2.4 %(V) 15.3 %(V) does not ignite (DIN 51758, closed cup) (DIN 51794)
not self-igniting
Suitable extinguishing media: foam, dry powder, water spray, carbon dioxide Hazards during fire-fighting: carbon oxides, nitrogen oxides The substances/groups of substances mentioned can be released in case of fire. Under certain conditions in case of fire other hazardous combustion products may be generated. Protective equipment for fire-fighting: Firefighters should be equipped with self-contained breathing apparatus and turn-out gear. Further information: Collect contaminated extinguishing water separately, do not allow to reach sewage or effluent systems. Impact Sensitivity: Remarks:
Based on the chemical structure there is no shock-sensitivity.
6. Accidental release measures
Personal precautions: Wear appropriate respiratory protection. Use personal protective clothing. Ensure adequate ventilation. Environmental precautions: This product is not regulated by RCRA. This product is not regulated by CERCLA ('Superfund'). Cleanup: Spills should be contained, solidified, and placed in suitable containers for disposal.
Safety Data Sheet
1,4-Butanediol
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7. Handling and Storage
Handling General advice: See MSDS section 10 - Stability and reactivity. See MSDS section 5 - Fire fighting measures. Protection against fire and explosion: Prevent electrostatic charge - sources of ignition should be kept well clear - fire extinguishers should be kept handy. Storage General advice: Containers should be stored tightly sealed in a dry place. Keep container tightly closed. Storage stability: Storage temperature: 20 C Storage duration: 24 Months From the data on storage duration in this safety data sheet no agreed statement regarding the warrantee of application properties can be deduced.
8. Exposure Controls and Personal Protection
Advice on system design: Provide local exhaust ventilation to control vapours/mists. Personal protective equipment Respiratory protection: Wear respiratory protection if ventilation is inadequate. Wear a NIOSH-certified (or equivalent) organic vapour respirator. For emergency or non-routine, high exposure situations, use a NIOSH-certified full facepiece pressure demand self-contained breathing apparatus (SCBA) or a full facepiece pressure demand supplied-air respirator (SAR) with escape provisions. Observe OSHA regulations for respirator use (29 CFR 1910.134). Hand protection: Chemical resistant protective gloves, Consult with glove manufacturer for testing data. Eye protection: Wear face shield or tightly fitting safety goggles (chemical goggles) if splashing hazard exists. Body protection: Body protection must be chosen depending on activity and possible exposure, e.g. head protection, apron, protective boots, chemical-protection suit. General safety and hygiene measures: Eye wash fountains and safety showers must be easily accessible. Wear protective clothing as necessary to minimize contact.
9. Physical and Chemical Properties
Form: Odour: Colour: pH value: Melting point: boiling temperature: Vapour pressure: Density: oily, liquid almost odourless colourless 7.2 - 7.9 20.4 C 230 C < 1 mbar 1.02 g/cm3
( 500 g/l, 20 C) (DIN 19268) ( 1,013 hPa) Literature data. ( 1,013 hPa) ( 20 C) ( 20 C, 1,013 hPa) liquid
Safety Data Sheet
1,4-Butanediol
Revision date : 2012/02/27 Version: 1.0
Relative density: Partitioning coefficient n-octanol/water (log Pow): Viscosity, dynamic: Particle size: 1.02 -0.88
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( 20 C, 1,013 hPa) (in liquid state), Literature data. ( 25 C) (OECD Guideline 107) The data refers to the undissociated form of the substance. ( 20 C) The substance / product is marketed or used in a non solid or granular form. ( 25 C) miscible miscible in all proportions
84.9 mPa.s
Solubility in water: Miscibility with water: Solubility (qualitative): Molar mass:
> 1,000 g/l
soluble solvent(s): organic solvents, 90.12 g/mol
10. Stability and Reactivity
Conditions to avoid: Avoid all sources of ignition: heat, sparks, open flame. Substances to avoid: strong oxidizing agents Hazardous reactions: The product is chemically stable. Reacts with oxidizing agents. Decomposition products: Hazardous decomposition products: carbon monoxide, carbon dioxide Possible decomposition products: tetrahydrofuran Thermal decomposition: < 200 C No exothermic decomposition within the mentioned temperature range. Corrosion to metals: Not corrosive to: iron aluminum Stainless steel Oxidizing properties: Based on its structural properties the product is not classified as oxidizing.
11. Toxicological information
Acute toxicity Information on: 1,4-Butanediol Information on: 1,4-Butanediol ---------------------------------Oral: Type of value: LD50 Species: rat (male/female) Value: 1,500 mg/kg (BASF-Test) Inhalation: Type of value: LC50 Species: rat (male/female) Value: > 5.1 mg/l (OECD Guideline 403) Exposure time: 4 h
Safety Data Sheet
1,4-Butanediol
Revision date : 2012/02/27 Version: 1.0 Page: 6/8 (30041337/SDS_GEN_US/EN)
An aerosol was tested. No mortality was observed. The value meets the highest applied test concentration. Dermal: Type of value: LD50 Species: rat (male/female) Value: > 2,000 mg/kg (BASF-Test) The value meets the highest applied test concentration. No mortality was observed. Irritation / corrosion Information on: 1,4-Butanediol ---------------------------------Skin: Species: rabbit Result: non-irritant Method: Draize test Eye: Species: rabbit Result: non-irritant Method: Draize test Sensitization: Guinea pig maximization test Species: guinea pig Result: Non-sensitizing. Aspiration Hazard: not applicable
12. Ecological Information
Fish Acute: OECD 203; ISO 7346; 84/449/EEC, C.1 static Pimephales promelas/LC50 (96 h): > 30,000 mg/l The details of the toxic effect relate to the nominal concentration. Chronic: Study scientifically not justified. Aquatic invertebrates Acute: OECD Guideline 202, part 1 static Daphnia magna/EC50 (48 h): 813 mg/l The statement of the toxic effect relates to the analytically determined concentration.
Chronic: OECD Guideline 202, part 2 semistatic Daphnia magna (NOEC) 21 d > 85 mg/l Aquatic plants Toxicity to aquatic plants: DIN 38412 Part 9 green algae/EC50 (72 h): > 500 mg/l Nominal concentration. Microorganisms
Safety Data Sheet
1,4-Butanediol
Revision date : 2012/02/27 Version: 1.0
Toxicity to microorganisms: other Protozoa/EC50 (40 h): > 15,000 mg/l OECD Guideline 209 activated sludge, industrial/EC20 (30 min): > 788 mg/l Nominal concentration. Degradability / Persistence Biological / Abiological Degradation Test method: OECD 301C; ISO 9408; 92/69/EEC, C.4-F (aerobic), activated sludge Method of analysis: BOD of the ThOD Degree of elimination: approx. 74 - 96 % (14 d) Test method: Method of analysis: Degree of elimination: Evaluation: OECD Guideline 302 B (aerobic), activated sludge, industrial DOC reduction 90 - 100 % (7 d) Readily biodegradable (according to OECD criteria).
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Hydrolysis Test method: Half-life:
OECD Guideline 111 (abiotic) pH7 (25 C)
Bioaccumulation Because of the n-octanol/water distribution coefficient (log Pow) accumulation in organisms is not to be expected.
13. Disposal considerations
Waste disposal of substance: Do not discharge substance/product into sewer system. Dispose of in a RCRA-licensed facility. Dispose of in accordance with national, state and local regulations. Container disposal: Dispose of in a licensed facility. Recommend crushing, puncturing or other means to prevent unauthorized use of used containers.
14. Transport Information
Land transport USDOT Not classified as a dangerous good under transport regulations
Sea transport IMDG Not classified as a dangerous good under transport regulations
Air transport IATA/ICAO Not classified as a dangerous good under transport regulations
Safety Data Sheet
1,4-Butanediol
Revision date : 2012/02/27 Version: 1.0 Page: 8/8 (30041337/SDS_GEN_US/EN)
15. Regulatory Information
Federal Regulations Registration status: Chemical TSCA, US OSHA hazard category:
released / listed Acute target organ effects reported; Toxic - oral
EPCRA 311/312 (Hazard categories):
Acute;
16. Other Information
NFPA Hazard codes: Health : 1 Fire: 1 HMIS III rating Health: 1
Reactivity:
Special:
Flammability:
Physical hazard: 0
NFPA and HMIS use a numbering scale ranging from 0 to 4 to indicate the degree of hazard. A value of zero means that the substance possesses essentially no hazard; a rating of four indicates extreme danger. Although similar, the two rating systems are intended for different purposes, and use different criteria. The NFPA system was developed to provide an on-the-spot alert to the hazards of a material, and their severity, to emergency responders. The HMIS system was designed to communicate workplace hazard information to employees who handle hazardous chemicals.
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MSDS Prepared by: BASF NA Product Regulations
[email protected]
MSDS Prepared on: 2012/02/27 IMPORTANT: WHILE THE DESCRIPTIONS, DESIGNS, DATA AND INFORMATION CONTAINED HEREIN ARE PRESENTED IN GOOD FAITH AND BELIEVED TO BE ACCURATE , IT IS PROVIDED FOR YOUR GUIDANCE ONLY. BECAUSE MANY FACTORS MAY AFFECT PROCESSING OR APPLICATION/USE, WE RECOMMEND THAT YOU MAKE TESTS TO DETERMINE THE SUITABILITY OF A PRODUCT FOR YOUR PARTICULAR PURPOSE PRIOR TO USE. NO WARRANTIES OF ANY KIND, EITHER EXPRESSED OR IMPLIED, INCLUDING WARRANTIES OF MERCHANTABILITY OR FITNESS FOR A PARTICULAR PURPOSE, ARE MADE REGARDING PRODUCTS DESCRIBED OR DESIGNS, DATA OR INFORMATION SET FORTH, OR THAT THE PRODUCTS, DESIGNS, DATA OR INFORMATION MAY BE USED WITHOUT INFRINGING THE INTELLECTUAL PROPERTY RIGHTS OF OTHERS. IN NO CASE SHALL THE DESCRIPTIONS, INFORMATION, DATA OR DESIGNS PROVIDED BE CONSIDERED A PART OF OUR TERMS AND CONDITIONS OF SALE. FURTHER, YOU EXPRESSLY UNDERSTAND AND AGREE THAT THE DESCRIPTIONS, DESIGNS, DATA, AND INFORMATION FURNISHED BY OUR COMPANY HEREUNDER ARE GIVEN GRATIS AND WE ASSUME NO OBLIGATION OR LIABILITY FOR THE DESCRIPTION, DESIGNS, DATA AND INFORMATION GIVEN OR RESULTS OBTAINED, ALL SUCH BEING GIVEN AND ACCEPTED AT YOUR RISK. END OF DATA SHEET
