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IV PO Conversions

Below are recommendations for conversion of IV medications to PO medications. Oral therapy may not be appropriate for all patients. A considerable cost savings may be realized by promptly changing patients to oral therapy when indicated.

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7K views1 page

IV PO Conversions

Below are recommendations for conversion of IV medications to PO medications. Oral therapy may not be appropriate for all patients. A considerable cost savings may be realized by promptly changing patients to oral therapy when indicated.

Uploaded by

damondouglas
Copyright
© Attribution Non-Commercial (BY-NC)
We take content rights seriously. If you suspect this is your content, claim it here.
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Download as DOC, PDF, TXT or read online on Scribd
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University of Maryland Medical Center

Department of Pharmacy Services

Medications Conversions (IV to PO) Recommendations

Oral therapy should be considered in any patient receiving intravenous medications and capable of
taking oral medications (i.e. eating, taking other PO medications, adequate gut function). Below are
recommendations for conversion of IV medications to PO medications. Please note that oral therapy
may not be appropriate for all patients (i.e. oral regimens do not achieve adequate serum
concentrations). Lastly, a considerable cost savings may be realized by promptly changing patients to
oral therapy when indicated.

IV regimen IV dose Cost PO regimen PO dose Cost/


/daya daya
Acyclovir (Zovirax ®) 350 mg q8h $ 4 Acyclovir (Zovirax®) 800 mg 5x/d < $ 1

Ampicillin 0.5-3 gm q4- < $ 1 Ampicillin 250-500 mg < $ 1


6h q6h
Amoxicillin 500 mg q8h
Ampicillin/sulbactam 1.5 gm q6h $ 23 Amoxicillin/clavulanateb 875 mg q12h $ 6
(Unasyn ®) (Augmentin®)
Azithromycin (Zithromax®) 500 mg q24h $ 18 Azithromycin (Zithromax®) 500 mg q24h $5

Cefazolin (Ancef ®) 1 gm q8h $ 12 Cephalexinb (Keflex®) 500 mg q6h $1

Ceftriaxone (Rocephin®) 1 gm q24h $ 26 Cefpodoximeb (Vantin®) 200 mg q12h $5

Ciprofloxacin (Cipro®) 400 mg q12h $ 49 Ciprofloxacin (Cipro®) 500 mg q12h $6

Clindamycin (Cleocin®) 600 mg q8h $ 10 Clindamycin (Cleocin®) 300 mg q6h $7

Doxycycline 100 mg q12h $ 2 Doxycycline 100 mg q12h < $ 1

Erythromycin (Erythrocin®) 500 mg q6h $ 5 Erythromycin (E-mycin®) 500 mg q6h $1


Clarithromycin (Biaxin®) 500 mg q12h $5
Azithromycin (Zithromax®) 250 mg q24h $5
Fluconazole (Diflucan®) 200 mg q24h $ 64 Fluconazole (Diflucan®) 200 mg q24h $9

Ketorolac (Toradol®) 15-30 mg q6h $ 24 Ibuprofen 600-800 mg < $ 1


q4-6h
Levofloxacin (Levaquin®) 500 mg q24h $ 31 Levofloxacin (Levoquin®) 250 mg q24h $ 5
500 mg q24h $ 6
Metronidazole (Flagyl®) 500 mg q8h $ 5 Metronidazole (Flagyl®) 500 mg q8h $1

Ranitidine (Zantac®) 50 mg q8h $ 9 Nizatidine (Axid®) 150 mg q12h < $ 1

Trimethoprim/ 325 mg q8h $ 6 Trimethoprim/ 2 DS tabs q8h < $ 1


Sulfamethoxazole Sulfamethoxazole
(Bactrim®) (Bactrim®)
a Cost is the approximate acquisition price of drug (rounded to the nearest dollar) excluding dispensing and
administration fees.
b Oral regimens as compared to IV regimens may not achieve adequate serum concentrations to treat all
infections

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