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Drug Study - Dexamethasone (Decilone)

Brand Name: Decilone Generic name: Dexamethasone Indications: rheumatoid arthritis, systemic lupus, acute gouty arthritis, psoriatic arthritis, ulcerative colitis, and Crohn's disease. Severe allergic conditions: bronchial asthma, allergic rhinitis, drug-induced dermatitis, and contact and atopic dermatitis. Chronic skin conditions: dermatitis herpetiformis, pemphigus, severe psoriasis and severe seborrheic dermatitis. Chronic allergic and inflammatory conditions of the uvea, iris, conjunctiva a

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1K views3 pages

Drug Study - Dexamethasone (Decilone)

Brand Name: Decilone Generic name: Dexamethasone Indications: rheumatoid arthritis, systemic lupus, acute gouty arthritis, psoriatic arthritis, ulcerative colitis, and Crohn's disease. Severe allergic conditions: bronchial asthma, allergic rhinitis, drug-induced dermatitis, and contact and atopic dermatitis. Chronic skin conditions: dermatitis herpetiformis, pemphigus, severe psoriasis and severe seborrheic dermatitis. Chronic allergic and inflammatory conditions of the uvea, iris, conjunctiva a

Uploaded by

mikErlh
Copyright
© Attribution Non-Commercial (BY-NC)
We take content rights seriously. If you suspect this is your content, claim it here.
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Brand Name: Decilone

Generic name: Dexamethasone


Indications: rheumatoid arthritis, systemic lupus, acute gouty arthritis, psoriatic arthritis,
ulcerative colitis, and Crohn's disease. Severe allergic conditions: bronchial
asthma, allergic rhinitis, drug-induced dermatitis, and contact and atopic
dermatitis. Chronic skin conditions: dermatitis herpetiformis, pemphigus,
severe psoriasis and severe seborrheic dermatitis. Chronic allergic and
inflammatory conditions of the uvea, iris, conjunctiva and optic nerves of the
eyes Blood cell cancers (leukemias), and lymph gland cancers (lymphomas).
Blood diseases: idiopathic thrombocytopenia purpura ; autoimmune hemolytic
anemia.
Drug Classification: Synthetic adrenal corticosteroid; glucocorticoid type.
Mechanism of Action: Corticosteroids are natural substances produced by the adrenal
glands located adjacent to the kidneys. Corticosteroids have potent anti-
inflammatory properties by preventing phospholipid release, decreasing
eosinophil action and a number of other mechanisms. Dexamethasone, a
corticosteroid, is similar to a natural hormone produced by your adrenal glands.
It often used to replace this chemical when your body does not make enough of
it.
Dosage PO: initial, 0.75-9 mg/day; maintenance, gradually reduce to minimum effective
dose (0.5-3 mg/day)
Special precaution: Tell your doctor and pharmacist if you are allergic to
dexamethasone, if you're taking in anti- coagulants, and if you are pregnant.
Pregnancy risk: Dexamethasone can be used in pregnancy, but is generally avoided.
Adverse reaction: stomach irritation,vomiting,headache,dizziness, insomnia,
restlessness, depression anxiety, acne, increased hair growth, easy
bruising,irregular or absent menstrual periods, skin rash swollen face, lower
legs, or ankles vision problems, cold or infection that lasts a long time, muscle
weakness, black or tarry stool.
Contraindications: Infection, peptic ulcer, acute glumerulonephritis
Form: Tablet
Nursing Responsibility:
 Assess patients on long term therapy have blood tests to determine glucose
levels an electrolyte balance
 Assess patients muscles for weakness and wasting
(continuation Decilone)
 Assess for signs and symptoms of other diseases because adrecocorticoids mask
the severity of most illnesses.
 Monitor BP at least 2 times daily unil the patient is stabilized on a maintenance
dose. Report increase in BP.
 Assess for GI bleeding when patient is on a long term therapy
 Teach patient or family to take medication with food, to be careful to avoid falls
because steroids makes the bones more usceptible to fractures, the need to
slowly withdrawing the drug when therapy is completed so that the patients own
adrenal cortex will gradually be reactivated to take over the productions of
hormone, the need to maintain general hygiene to prevent infection because
antibody productin is decreased by adrenocorticosteroids.

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