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Ch8 Predictive Methods Using Protein Sequences

This document summarizes predictive methods for analyzing protein sequences, including predicting secondary structure, solvent accessibility, transmembrane segments, and subcellular localization. It lists specific tools such as PHDsec, PROFsec, and PSIPRED that can be used for secondary structure prediction, and tools like PHDacc, PROFacc, and Jpred for solvent accessibility prediction. TopPred and TMHMM are mentioned as options for predicting transmembrane segments, and PSORT and TargetP for subcellular localization prediction.

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mirabilis_annee
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233 views

Ch8 Predictive Methods Using Protein Sequences

This document summarizes predictive methods for analyzing protein sequences, including predicting secondary structure, solvent accessibility, transmembrane segments, and subcellular localization. It lists specific tools such as PHDsec, PROFsec, and PSIPRED that can be used for secondary structure prediction, and tools like PHDacc, PROFacc, and Jpred for solvent accessibility prediction. TopPred and TMHMM are mentioned as options for predicting transmembrane segments, and PSORT and TargetP for subcellular localization prediction.

Uploaded by

mirabilis_annee
Copyright
© Attribution Non-Commercial (BY-NC)
Available Formats
Download as PPT, PDF, TXT or read online on Scribd
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Predictive Methods Using

Protein Sequences
• Secondary Structure Prediction
• Solvent Accessibility
• Transmembrane Segments
• Subcellular Localization
Secondary Structure Prediction
• PHDsec (http://www.predictprotein.org/ )
• PROFsec (http://cubic.bioc.columbia.edu/predictprotei
n/ )
• PSIPRED (
http://bioinf.cs.ucl.ac.uk/psipred/ )
Solvent Accessibility
• PHDacc (http://www.predictprotein.org/ )
• PROFacc (http://cubic.bioc.columbia.edu/predictprotei
n/ )
• Jpred (http://www.compbio.dundee.ac.uk/~
www-jpred/ )
Transmembrane Segments
outside

inside
• TopPred (http://bioweb.pasteur.fr/seqanal/in
terfaces/toppred.html )
• TMHMM
(http://www.cbs.dtu.dk/services/TMHMM/
)
Subcellular Localization
• PSORT (http://psort.ims.u-tokyo.ac.jp/ )
• TargetP (http://www.cbs.dtu.dk/services/Ta
rgetP/ )

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