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Brand Name: Aprovel Generic Name: Irbesartan Indications: For The Treatment

Aprovel is an antihypertensive drug used to treat hypertension and renal disease in patients with hypertension and type 2 diabetes. It works by selectively blocking the binding of angiotensin II to receptor sites, inhibiting vasoconstriction and aldosterone secretion. The standard dosage is 150 mg daily, which can be increased to 300 mg or combined with other antihypertensives if needed. Common side effects include fatigue, dizziness, chest pain, edema, and rashes.

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4K views2 pages

Brand Name: Aprovel Generic Name: Irbesartan Indications: For The Treatment

Aprovel is an antihypertensive drug used to treat hypertension and renal disease in patients with hypertension and type 2 diabetes. It works by selectively blocking the binding of angiotensin II to receptor sites, inhibiting vasoconstriction and aldosterone secretion. The standard dosage is 150 mg daily, which can be increased to 300 mg or combined with other antihypertensives if needed. Common side effects include fatigue, dizziness, chest pain, edema, and rashes.

Uploaded by

ianecunar
Copyright
© Attribution Non-Commercial (BY-NC)
We take content rights seriously. If you suspect this is your content, claim it here.
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Download as DOC, PDF, TXT or read online on Scribd
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Brand Name: Aprovel

Generic Name: Irbesartan


Indications: For the treatment of hypertension & treatment of renal disease in patients with
hypertension and type II diabetes mellitus, as part of an antihypertensive drug
regimen.
Drug Classification: Antihypertensive
Mechanism of Action: Inhibits the vasoconstricting and aldosterone-secreting effects of
angiotensin II by selectively blocking
binding of angiotensin Ii to receptor sites in many tissues.
Therapeutic Effect: Lowers blood pressure.
Dosage: 150 mg daily. May be increased to 300 mg or combined with other antihypertensive
agents if patient is not sufficiently controlled. In hemodialyzed patients &
elderly>75 yr 75 mg daily
Special Precaution: Intravascular volume depletion, renovascular hypertension, renal
impairment, kidney transplantation, hyperkalemia, aortic & mitral valve stenosis,
obstructive hypertrophic, cardiomyopathy, ischemic cardiopathy, ischemic
CV disease, primary aldosteronism & patients whose vascular tone & renal function
depend predominantly on the activity of the rennin-angiotensin-aldosterone system.
Pregnancy Risk Category: C (D in 2nd and 3rd trimesters)
Adverse Reaction:
CNS: fatigue, anxiety, dizziness, headache., CV: chest pain, edema, tachycardia.
EENT: pharyngitis, rhinitis, sinus abnormality. GI: UTI. Metabolic: hyperkalemia.
Musculoskeletal: musculoskeletal trauma or pain. Respiratory: URTI. Skin: rashes.
Contraindications: Pregnancy and lactation
Form: Tablets: 75 mg, 150 mg, and 300 mg.
Nursing Responsibilities:
 Monitor patient’s BP regularly.
 Monitor patient’s electrolytes.
 Assess patient’s and family’s knowledge of drug therapy.
 Give with a diuretic if drug is needed to control blood pressure.
 Place in supine position and give an IV infusion of NSS if patient becomes
hypotensive.
 Tell patient that drug may be taken once daily with or without food.
 Instruct client to avoid driving and hazardous activities until CNS effects of drug are
known.

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