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Cell Membrane and Transport Mechanisms

The cell membrane is semi-permeable, allowing small polar molecules and lipids to pass through but blocking ions and larger molecules. Materials enter and exit the cell through either passive transport mechanisms like diffusion and osmosis, which do not require energy, or active transport mechanisms like protein pumps, which use ATP to transport against gradients. Active transport includes bulk mechanisms of endocytosis, exocytosis, and phagocytosis that move larger packages of molecules in and out of the cell.
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382 views

Cell Membrane and Transport Mechanisms

The cell membrane is semi-permeable, allowing small polar molecules and lipids to pass through but blocking ions and larger molecules. Materials enter and exit the cell through either passive transport mechanisms like diffusion and osmosis, which do not require energy, or active transport mechanisms like protein pumps, which use ATP to transport against gradients. Active transport includes bulk mechanisms of endocytosis, exocytosis, and phagocytosis that move larger packages of molecules in and out of the cell.
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Cell membrane and transport mechanisms

Remember that all material that the cell gets from the environment or sends to the environment has to go through the cell or plasma membrane. The membrane is basically a phospholipid bi-layer with various proteins embedded into it. What's key to realize is that the cell membrane is semi permeable that is some materials can get through the membrane while others can't.

Chemicals that can pass through the membrane Water Carbon dioxide Oxygen Other very small polar molecules such as ammonia Lipids such as cholesterol

Chemicals that cannot pass through the membrane All ions including hydrogen ions! mid to large polar molecules including glucose Amino acids Macromolecules such as proteins, polysaacharides

Transport mechanisms fall into two categories passive and active. Passive transport mechanisms do not require the cell to do work for the substance to enter or leave the cell. Instead the energy involved comes from the kinetic energy of the molecules in solution. Active transport mechanisms involve the cell to use cellular energy usually in the form of ATP to power special protein pumps to bring material into the cell.

Passive transport mechanisms Simple diffusion Osmosis Facilitated Diffusion


Active Transport mechanisms Active transport via protein pumps Bulk flow mechanisms

Simple protein channels Gated channels

endocytosis o phagocytosis o pinocytosis exocytosis

The passive transport mechanisms and the protein pump mechanisms involve movement of substances as single molecules across the membrane. The "bulk" flow mechanisms endocytosis and exocytosis enable the cell to take in very large packages of molecules...say a food item from the environment. Many books treat these bulk flow mechanisms as seperate from active transport for that reason.

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