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Open Science Data Repository

The NASA Open Science Data Repository (OSDR) enables access to space-related data from experiments and missions that investigate biological and health responses of terrestrial life to spaceflight. The goal of OSDR is to enable multi-modal and multi-hierarchical fundamental space life science data be reused toward basic science, applied science, and operational outcomes for space exploration and knowledge discovery. These data include ‘omics, phenotypic, physiological, behavioral, hardware, environmental telemetry; raw, processed; tabular, text, code, bioimaging, and video.

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Open Science Data Repository

Search and upload spaceflight datasets

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Latest News

Announcing NASA’s GeneLab for High Schools (GL4HS) Program: Summer 2025 NASA’s GeneLab for High Schools (GL4HS) announces its expanded 2025…

NBISC Launches New Biospecimen Portal to Accelerate Research The NASA Biological Institutional Collection (NBISC) is a biorepository of non-human samples…

Explore Summer Internship Opportunities with OSDR Are you passionate about open science and excited to contribute to space biology and…

By the Numbers

NASA Open Science Data Repositories expands scientists’ access to space-related experiments that explore the biological response of terrestrial biology to spaceflight environments. Our mission is to maximize the utilization of the valuable biological research resources and enable new discoveries.

TODAY

531

Studies

995

Datasets

Latest Datasets

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OSD-689

Single-cell analysis identifies conserved features of immune dysfunction in simulated microgravity and spaceflight (TRANSCRIPTOMICS)

OSD-782

Multi-omics profiling reveals ethylene signalling as a key pathway underlying both genetic and epigenetic responses to low-dose ionizing radiation in Arabidopsis (TRANSCRIPTOMICS)

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OSD-679

Head-Down Tilt As a Model for Intracranial and Intraocular Pressures, and Retinal Changes during Spaceflight (Eye, MRI, Optical Coherence Tomography, Tonometry, A-scan) (ALSDA)

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OSD-680

Head-Down Tilt As a Model for Intracranial and Intraocular Pressures, and Retinal Changes during Spaceflight (Optic Nerve, MRI) (ALSDA)

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OSD-681

Head-Down Tilt As a Model for Intracranial and Intraocular Pressures, and Retinal Changes during Spaceflight (Subcutaneous Tissue and Subdural Space, Body Temperature and Intracranial Pressure Biotelemetry) (ALSDA)

Publication Highlight

Spatiotemporal expression and control of haemoglobin in space

Space travel activates many genes, including those related to blood and hemoglobin production. This study used data from the NASA Open Science Data Repository, including samples from the NASA Twins Study, JAXA CFE study, and Inspiration4 mission, to explore how hemoglobin genes change over time and in different space conditions. The findings show how space affects blood gene activity, offering insights for future space research.

Selected spatiotemporal comparisons of a number of globin miRNAs in different cellular fractions are presented.

Visualization Tools

Data Visualization

GeneLab’s latest software release includes a new visualization portal to interact with gene expression data from space-related omics experiments. The enhanced portal includes a new search interface, new plots and layout, and advanced settings to customize the plots.

Go to Visualization Portal

RadLab

RadLab is a portal that aims to provide a single point of access to radiation telemetry data from multiple databases maintained by multiple space agencies.

Go to RadLab Portal

Environmental Data App (EDA)

The Environmental Data App (EDA) is a portal where users can visualize and compare ISS (International Space Station) cabin environmental telemetry data and radiation data gathered from spaceflight missions.

Testimonials

Dr Begum Mathyk – Obstetrician and Gynecologist

The important thing is not to stop questioning. Curiosity has its own reason for existing. – Albert Einstein

It mirrors the continuous learning and discovery facilitated by the NASA OSDR open science platform, which has been instrumental in expanding my research and allowed me to utilize multiple datasets. This accessibility has not only enriched my resources but has significantly strengthened the analyses and outcomes of my work.

Read more testimonials

Open Science Projects

Open Science Projects primary goals aim to increase collaborative scientific data sharing, analysis, and more rapid scientific advancement.

ALSDA

GeneLab

NBISC

BSP

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