Mark Messenbaugh’s Post

Proteomics is entering a transformative era, and we are excited to be collaborating with Illumina and pharma leaders on a new proteomics pilot program with the UK Biobank. The new Illumina Protein Prep NGS-based proteomics platform, powered by our SOMAmer™ technology, will provide deeper biological insights into this cohort. We look forward to sharing the data from this project with the research community later this year.   Read more about this collaboration at: https://lnkd.in/eFuum3ed   Learn about our work with biobanks around the world: https://lnkd.in/ejvBW5RV #Proteomics #Illumina

I’m thrilled to see the outcomes of our collaboration with Illumina, Tecan, and various pharmaceutical partners, which has led to the achievement of 9,000 protein measurements for the UK Biobank project. Alongside Thermo Fisher Scientific's contributions to the UK Biobank project, it’s clear that we are entering a new era in population proteomics. This breakthrough allows us to correlate circulating proteins with genetic predispositions, offering a promising avenue to improve human health. While this news is gaining attention in the mainstream media, Standard BioTools has been at the forefront of supporting high-throughput proteomics for large biobanks and cohorts for over two decades, analyzing more than 225,000 biobank samples. The SomaScan™ platform has been used in more than 1,200 peer-reviewed papers. Our microarray-based SomaScan assay can measure over 11,000 proteins in plasma, serum, and cerebrospinal fluid, enabling direct comparisons without the need for bridging samples. Furthermore, our SomaScan assay is the only high-plex proteomics solution that can be scaled with unmatched precision.   🎯 Scaling with precision https://lnkd.in/gJ-DXF3x 🎯 SomaScan assay biobanks https://lnkd.in/gmaHVtMJ 🎯 SomaScan assay publications https://lnkd.in/gkESCpV7

At Precision Quantomics, we're always on the lookout for advancements that can push the boundaries of what's possible in drug discovery. That's why I'm excited to share this insightful webinar from Precision Quantomics by Dr.Faizan Zubair. If you missed Dr.Zubair's engaging session on December 4th, here's your chance to catch up. His discussion on how proteomics technologies are driving breakthroughs is not just informative but essential for those of us committed to innovation in the biotech sector. Unlock this valuable resource here: https://lnkd.in/gpgs9Tgu # Key Takeaways: - Cutting-edge applications of proteomics - This is where we see the future unfolding at Precision Quantomics. - Real-world insights transforming drug discovery - Practical knowledge that we can apply to our research. - Expert knowledge from industry leaders - Learning from the best to stay at the forefront of our field. I encourage everyone in the life sciences or biotech space to watch this session. It's a must-see for staying ahead in the proteomics field, aligning perfectly with our mission at Precision Quantomics to harness the power of proteomics for better health outcomes. #Proteomics #DrugDevelopment #PrecisionQuantomics #LCMS #BiotechInnovation #LifeSciences

🎥 Missed our proteomics webinar? We've got you covered! On December 4, Dr. Faizan Zubair led an insightful session exploring how proteomics technologies are transforming drug discovery and development. If you weren’t able to join us live, you can still catch the webinar on demand! 🔗 Click here to sign up and unlock this valuable resource to learn how proteomics can accelerate your research: https://lnkd.in/gpgs9Tgu 💡 Don’t miss out on: ✅ Cutting-edge applications of proteomics ✅ Real-world insights into drug discovery ✅ Expert advice from a leading scientist #Proteomics #DrugDiscovery #WebinarOnDemand #LifeSciences #BiotechInnovation #PrecisionMedicine #PharmaResearch

Insightful workflow on how to speed up LC-MS based proteomics analysis without sacrificing data quality! Register to this exciting and informative webinar to hear what the experts have to say.

Exciting news from Quantum-Si! Our latest preprint demonstrates how protein barcoding, powered by the #Platinum® instrument and Next-Generation Protein Sequencing™ is redefining proteomics. Highlights of this paper include: - Validated Peptide Barcodes: Development and validation of eight peptide barcodes designed to minimize detection bias and maximize sensitivity. - Streamlined Workflow: Less than one hour of hands-on time with minimal sample input. - Broad Dynamic Range: Robust detection of low-abundance proteins To discover how these innovations are advancing protein characterization and transforming therapeutic strategies, read the Preprint: https://bit.ly/401Meku Check out the full Press Release here: https://lnkd.in/enqy7PgW #Proteomics #NGPS #ProteinBarcoding #QSI

Protein barcoding has emerged as an incredibly powerful tool, capable of high sensitivity with broad utilisation for multiplexed identification and characterization of proteins. Just another example of how Next-Generation Protein Sequencing™ (NGPS) is game changing!

🌟 The HUPO World Congress for Proteomics is starting soon! 🌟 We’re excited to announce that Affinisep will be exhibiting and showcasing our innovative Sample Preparation Solutions designed to streamline and enhance your proteomic workflows. If you're attending, don’t miss the chance to visit us at booth number 15 to explore how our cutting-edge products can support your research, including: - Peptide desalting with BioSPE® PurePep - Peptide fractionation with BioSPE® PepFrac - Glycopeptide enrichment with BioSPE® GlycaClean - Intact protein purification with BioSPE® PureProt - Magnetic beads removal after SP3 with BioSPE® BeadRem Explore our full range of sample preparation solutions for Proteomics, including SPE Spin, SPE Tips, and 96 & 384 SPE microelution plates. We’re looking forward to meeting you and discussing how we can contribute to your research success! #proteomics #HUPO2024 #massspectrometry #samplepreparation #LCMS #bioanalysis #biomarkers #glycopeptide #cancerresearch #singlecell #HUPOEuPA2024 #LifeScience #SamplePreparation #ProteomicsResearch #Biotech #ResearchTools

In our latest blog post, our Chief Scientist - Dr Andrew Webb, a leading expert with decades of experience in proteomics and biomolecular research, explores the transformative power of proteomics in Targeted Protein Degradation (TPD). His deep insights into the science behind proteomics and its real-world applications is a window into how how he believes it will reshape drug discovery in the future. "We are just scratching the surface of what this technology can achieve for patients and society." 🔗 Read the full blog post https://lnkd.in/gApwRu7E #TPD #Proteomics #DrugDiscovery #degraders #Biotech #BioPharma

Thanks Andrew Webb -- Interesting insights into a vibrant and fast-paced space that should be watched closely. Below, ChatGPT has done a great job in explaining what Targeted Protein Degradation (TPD) is, and why you should care. My prompt: "What is the best way or analogy to describe what TPD is to a LinkedIn audience that ranges from technologists, software, product and design people to investors, executives, and scientists? And why should they care about TPD?" Response (ChatGPT 4o): "Think of TPD like a highly specialized recycling program. In a smart city, there are certain items—waste or broken components—that need to be completely removed or repurposed to keep everything functioning smoothly. Traditional methods may just disable or store those items, but they still take up space. TPD, on the other hand, finds the specific broken components (proteins), tags them for removal, and recycles them completely, freeing up resources and preventing future problems. In drug development, this targeted cleanup can lead to breakthroughs in treating diseases. The audience should care because, like smart cities rely on efficient recycling to optimize resources and ensure a sustainable future, TPD offers a transformative approach to drug development by eliminating harmful proteins that cause disease. For technologists, software developers, and product designers, this is akin to streamlining systems to remove inefficiencies and future-proof operations. Investors and executives should care because TPD is driving the next wave of biotech innovation, opening up entirely new therapeutic markets and potential revenue streams. And for scientists, TPD provides a breakthrough tool to address previously untreatable conditions, making it a game changer in the fight against complex diseases."