Oligonucleotide therapies (ONs), like siRNAs and ASOs, are at the forefront of modern medicine, offering hope for genetic, ophthalmic, and cardiovascular diseases. However, their interaction with the immune system poses unique challenges. From drug properties to delivery methods, every detail can impact immunogenicity. Our experts share strategies for analyzing and overcoming these hurdles in this comprehensive blog. Gain insights into: • Structural complexities of ONs. • Advances in delivery methods like lipid nanoparticles (LNPs). • Cutting-edge bioanalytical techniques, including electrochemiluminescence detection. Read more: https://hubs.li/Q037MR1J0 #Bioanalysis #Therapeutics #Innovation #Biopharma