Jes Broeng’s Post

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Professor and Director, DTU Entrepreneurship

Alzheimer’s – new paper in Nature Treatment of Alzheimer’s and Dementia (AD) remains one of the largest challenges in medicine. Tragically, the few antibody drugs on the market are often associated with serious side effects, such as brain swelling or bleeding. In contrast, increasing scientific evidence indicate positive potential using flickering light therapy for treating AD in a safe manner. This so-called light-based gamma entrainment using sensory stimuli (GENUS) shows considerable potential in both animal and human models. Dating back to 2016, we began work in this area in a collaboration between University of California, Berkeley and DTU - Technical University of Denmark – and have been pioneering novel GENUS solutions for more comfortable and convenient patient use. In the latest Nature, Scientific Reports we demonstrate the efficiency of these new solutions for stimulating the brain: https://lnkd.in/dKiKfh_K The coming years will be highly exciting as we see an increasing number of clinical trials and a rapidly growing global research community. Main credit for this work to my excellent co-authors and leading scientists Luna Skytte Hansen, Marcus Carstensen, Mark Henney, Ngoc Mai Nguyen, Martin William Thorning-Schmidt, Paul Michael Petersen & Tobias Søren Andersen Also a big thank you to the Innovation Fund Denmark for supporting this important work towards a treatment of AD. And finally, a huge congratulations to Marcus Carstensen – recently receiving the Young Researcher Award at the DTU - Technical University of Denmark – well deserved 👏 OptoCeutics DTU Electro DTU Compute DTU Entrepreneurship Vivienne Ming Jan Torleif Pedersen, PhD, MSc David Lindeman Lance Kriegsfeld

Light-based gamma entrainment with novel invisible spectral flicker stimuli - Scientific Reports

Light-based gamma entrainment with novel invisible spectral flicker stimuli - Scientific Reports

nature.com

Jes Broeng

Professor and Director, DTU Entrepreneurship

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For more general overview, please see this recent News feature, also in Nature: https://www.nature.com/articles/d41586-024-03147-1

Marcus Carstensen

A voracious appetite for books | Co-Founder & Chief Scientific Officer @Optoceutics | PhD | Dad, background in physics and engineering

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In the coming years, we will explore how this affects metabolite flow during deep sleep. Some intriguing research has already emerged regarding the impact on glymphatic flow. It's clear that we need sleep; however, not all stages of sleep contribute equally to the brain's ability to clear proteins. Current evidence suggests that it is deep sleep 😴☺️ that is linked to protein clearance, but further research is underway to investigate this topic more thoroughly. https://www.nature.com/articles/s41421-024-00701-z

Thomas Riisgaard Hansen

Managing Director at Digital Research Centre Denmark - DIREC

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Cool. Congrats on the research paper in Nature. Impressive project and results.

Interesting and certainly relevant.

Max Vellguth

Startup Factories @ TU Hamburg | PhD Graduate from DTU | Research Affiliate at MIT Sloan | Deeptech Entrepreneurship & Ecosystems

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Ali Harandi

Lab head, Associate Professor, Univ. Gothenburg, Univ. British Columbia, Senior Consultant

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Insightful. Congrats Jes

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