GenomeScan’s Post

Next Generation Sequencing (NGS) is revolutionizing the toxicology field by providing researchers with unprecedented tools to study toxins, their effects, and their impact on human and environmental health. Here is how NGS is making a difference: 💡 Identify previously unknown toxic substances. 💡 Assess the impact of toxins on ecosystems. 💡 Predict toxicity levels and develop safer products. 💡 Understand the molecular mechanisms of toxicity. NGS is our magnifying glass into the world of toxins, making the invisible visible and safeguarding our health and environment. Curious to learn more? Check our blog post here: https://lnkd.in/dzAWytin #toxicology #ngs

🚨 𝐂𝐚𝐥𝐥 𝐟𝐨𝐫 𝐀𝐛𝐬𝐭𝐫𝐚𝐜𝐭𝐬! 🚨 We are thrilled to announce that the 3𝐫𝐝 𝐈𝐧𝐭𝐞𝐫𝐧𝐚𝐭𝐢𝐨𝐧𝐚𝐥 𝐒𝐮𝐦𝐦𝐢𝐭 𝐨𝐧 𝐓𝐨𝐱𝐢𝐜𝐨𝐥𝐨𝐠𝐲 𝐚𝐧𝐝 𝐀𝐩𝐩𝐥𝐢𝐞𝐝 𝐏𝐡𝐚𝐫𝐦𝐚𝐜𝐨𝐥𝐨𝐠𝐲 will be held from 𝐌𝐚𝐲 22-24, 2025, in 𝐀𝐦𝐬𝐭𝐞𝐫𝐝𝐚𝐦, 𝐍𝐞𝐭𝐡𝐞𝐫𝐥𝐚𝐧𝐝𝐬! We invite researchers, scientists, industry experts, and academics to submit their abstracts and share their innovative work with a global audience. 𝐖𝐡𝐲 𝐒𝐮𝐛𝐦𝐢𝐭? Showcase your research to a global audience Network with leading professionals and experts Gain valuable feedback and recognition Contribute to the latest developments in Toxicology and Applied Pharmacology 🌐 𝐂𝐨𝐧𝐟𝐞𝐫𝐞𝐧𝐜𝐞 𝐖𝐞𝐛𝐬𝐢𝐭𝐞: https://lnkd.in/gsuWHJbu 📝 𝐀𝐛𝐬𝐭𝐫𝐚𝐜𝐭 𝐒𝐮𝐛𝐦𝐢𝐬𝐬𝐢𝐨𝐧: https://lnkd.in/gRNYUpid 💼 𝐑𝐞𝐠𝐢𝐬𝐭𝐫𝐚t𝐢𝐨𝐧 𝐋𝐢𝐧𝐤: https://lnkd.in/gapDY7Rd 📧 𝐄𝐦𝐚𝐢𝐥: istap2025@spectrumconferences.com Don't miss this opportunity to be part of a significant event in the field! Submit your abstract today and join us in Amsterdam for an inspiring and knowledge-rich experience. #Toxicology2025 #Pharmacology #Research #Conference #Amsterdam #Toxicology #Pharmacology #CallForAbstracts #ScienceConference #Amsterdam2025 #Science #Conference #CallForAbstracts #SubmitNow #Toxicology #AppliedPharmacology #Pharmacology #AbstractSubmission #CallForAbstracts #Research #ScienceConference #ToxicologyConference #PharmacologyConference #EnvironmentalToxicology #ClinicalToxicology #IndustrialToxicology #OccupationalToxicology #Toxicogenomics #RiskAssessment #RiskManagement #ToxicologyResearch #PharmacologyResearch #PublicHealth #ChemicalSafety #ToxicSubstances #EnvironmentalHealth #DrugSafety #HealthSciences #BiomedicalScience #RegulatoryScience #Toxins #HazardAssessment #BioanalyticalChemistry #Pharmaceuticals #DrugDevelopment #PharmaceuticalResearch #MedicalResearch #Chemistry #Biochemistry #MolecularToxicology #ForensicToxicology #ToxicologyStudies #HealthSafety #EnvironmentalScience #Pharma #PharmaScience #Pharmacokinetics #Pharmacodynamics #GlobalHealth #ScientificResearch #ResearchConference #InnovationInScience #Amsterdam2025 #SpectrumConferences

Application of OrganoGel in Metabolism and Toxicology Research The methods of drug toxicological research are primarily animal experiments, which extrapolate the effects observed in experimental animals to humans. The main aspects of new drug toxicity research include: acute toxicity studies, long-term toxicity studies, formulation toxicity studies, and special toxicity studies. The experimental methods are mainly divided into in vivo and in vitro tests. In vitro tests utilize isolated organs, cultured cells, cell organelles, and microorganisms for toxicity research. Traditional 2D cell cultures cannot construct a three-dimensional microenvironment, thus there is a significant difference in cell function compared to in vivo conditions. Three-dimensional (3D) culture uses special methods and materials to allow cells to grow in a three-dimensional manner, more closely resembling the growth patterns within the body, forming microstructures similar to those of tissues. 3D cell culture is mainly divided into scaffold-based 3D cell culture and scaffold-free 3D cell culture. Scaffold-free 3D cell culture is a simple and easy-to-operate method that does not require the addition of cell scaffolds. Instead, it utilizes cell culture vessels treated with cell-repellent materials or employs special systems such as hanging drop or microfluidic devices for cell cultivation. This prevents cell adhesion to the vessel surface, forcing them to aggregate and form cell spheroids. The 3D cell models obtained through this method possess a complete spherical structure, can spontaneously form extracellular matrix, and effectively simulate the oxygen and nutrient gradients found in in vivo environments.

𝗚𝗲𝗻𝗲𝘁𝗶𝗰 𝗧𝗼𝘅𝗶𝗰𝗼𝗹𝗼𝗴𝘆 𝗠𝗮𝗿𝗸𝗲𝘁 𝟮𝟬𝟮𝟰-𝟮𝟬𝟯𝟭. 𝗚𝗹𝗼𝗯𝗮𝗹 𝗥𝗲𝘀𝗲𝗮𝗿𝗰𝗵 𝗥𝗲𝗽𝗼𝗿𝘁 𝐑𝐞𝐪𝐮𝐞𝐬𝐭 𝐟𝐨𝐫 𝐒𝐚𝐦𝐩𝐥𝐞 𝐏𝐃𝐅: https://lnkd.in/gBR6GENw The Genetic Toxicology Market is growing rapidly due to increased research in genetic mutations and carcinogenesis. This field focuses on identifying and understanding substances that cause genetic damage. Driven by advancements in technology and rising regulatory requirements, the market is expanding as pharmaceutical and biotechnology companies prioritize genetic safety in drug development and environmental monitoring. 𝐓𝐨 𝐊𝐧𝐨𝐰 𝐭𝐡𝐞 𝐆𝐥𝐨𝐛𝐚𝐥 𝐒𝐜𝐨𝐩𝐞 𝐚𝐧𝐝 𝐃𝐞𝐦𝐚𝐧𝐝 𝐨𝐟 𝗚𝗲𝗻𝗲𝘁𝗶𝗰 𝗧𝗼𝘅𝗶𝗰𝗼𝗹𝗼𝗴𝘆 𝗠𝗮𝗿𝗸𝗲𝘁. 𝐑𝐞𝐪𝐮𝐞𝐬𝐭 𝐟𝐨𝐫 𝐒𝐚𝐦𝐩𝐥𝐞 𝐏𝐃𝐅: https://lnkd.in/gBR6GENw *𝗕𝘆 𝗧𝘆𝗽𝗲: Genotoxicity Screening Assays, GLP Standard Genotoxicity Assays *𝗕𝘆 𝗔𝗽𝗽𝗹𝗶𝗰𝗮𝘁𝗶𝗼𝗻: Mini Ames/Ames, Gene Mutation, In Vitro Micronucleus, Chromosome Aberration, Others *𝗕𝘆 𝗥𝗲𝗴𝗶𝗼𝗻: North America, Europe, Asia-Pacific, South America, Middle East & Africa *𝗕𝘆 𝗞𝗲𝘆 𝗣𝗹𝗮𝘆𝗲𝗿𝘀: Frontage Laboratories, Inc, Charles River Laboratories, Pharmaron, Labcorp, Syngene, Vivotecnia, Aurigene Pharmaceutical Services Limited, ERBC GROUP, Cardinal Health, Toxys, Abbott, Evotec #genetictoxicology #toxicology #genetics #bioscience #medicalresearch #healthcare #drugdevelopment #laboratoryresearch #environmentalsafety #genetictesting #biotechnology #safetyassessment #clinicalresearch #pharmacology #scienceresearch

✨ Meet our Esteemed Speakers! ✨ Join us for the 3rd International Summit on Toxicology and Applied Pharmacology in Amsterdam, Netherlands, from May 22-24, 2025! This premier event will bring together leading scientists, researchers, and industry experts from across the globe to share insights and innovations in toxicology and pharmacology. 🌍 This summit promises an inspiring lineup of sessions, workshops, and networking opportunities designed to foster innovation, collaboration, and knowledge exchange in toxicology and pharmacology. Connect with leading scientists, clinicians, and industry experts, and be a part of the future of toxicology and applied pharmacology! 🌐 𝐂𝐨𝐧𝐟𝐞𝐫𝐞𝐧𝐜𝐞 𝐖𝐞𝐛𝐬𝐢𝐭𝐞: https://lnkd.in/gsuWHJbu 📝 𝐀𝐛𝐬𝐭𝐫𝐚𝐜𝐭 𝐒𝐮𝐛𝐦𝐢𝐬𝐬𝐢𝐨𝐧: https://lnkd.in/gRNYUpid 💼 𝐑𝐞𝐠𝐢𝐬𝐭𝐫𝐚t𝐢𝐨𝐧 𝐋𝐢𝐧𝐤: https://lnkd.in/gapDY7Rd 📧 𝐄𝐦𝐚𝐢𝐥: istap2025@spectrumconferences.com Register now to secure your place and be part of the future of toxicology and pharmacology research. Let’s advance together in Amsterdam! #Toxicology #AppliedPharmacology #PharmacologyConference #ToxicologySummit #Amsterdam2025 #ToxicologyResearch #Pharmacology2025 #ToxPharma2025 #InternationalSummit #AmsterdamConference #ScienceInAmsterdam #DrugDevelopment #ToxicSubstances #PharmacologyScience #MedicalToxicology #ToxConference #PharmacologyMeet #ResearchInnovation #ToxicologyStudies #PharmaResearch #GlobalHealth #EnvironmentalTox #ToxPharmaSummit #DrugSafety #HealthInnovation #ChemicalsAndHealth #ToxLab #BioanalyticalChemistry #RiskAssessment #Toxicogenomics #DrugInteractions #HealthRisks #ChemistryAndHealth #PublicHealth #Toxicologists #PharmaIndustry #ResearchConference #MedicalResearch #SafetyAssessment #ClinicalToxicology #Pharmacokinetics #Pharmacodynamics #CancerResearch #EnvironmentalHealth #Biomedicine #ToxicityTesting #PharmaceuticalSciences #ChemicalExposure #ScienceNetworking #ExpertSpeakers #ScientificSessions #DrugTesting #Biomarkers #ToxInsights #Genotoxicity #Pathophysiology #Neurotoxicology #Immunotoxicology #Pharmacotoxicology #TransgenerationalEffects #HeavyMetals #GreenChemistry #ExperimentalPharmacology #Nanotoxicology #ForensicToxicology #DrugMetabolism #Biochemistry #ChemicalHazards #DrugReactions #HealthSafety #RegulatoryScience #OccupationalTox #PharmaSafety #Biopharmaceuticals #ChemResearch #InhalationToxicology #DrugDiscovery #PublicHealthTox #EnvironmentalPharma #PharmaInnovations #SafetyScience #NextGenPharma #BiochemicalScience #PharmacologyExperts #InnovationInHealth #MolecularTox #Conference2025 #HealthScience #HealthcareConference #MedicalScience #StemCells #GeneticToxicology #Workshop2025 #BiotechTox #ScientificResearch #ExpertPanels #ScienceForHealth #ClinicalScience #ResearchForum #LifeScience

We invite you to join our next exciting course, October 7th – 9th, as our expert team delivers “Introduction to Metabolomics for Toxicology”.   Location: School of Biosciences, University of Birmingham, United Kingdom, B15 2TT.   Dates: 7th – 9th October 2024   Event type: On-site, hands-on   Early bird rates: Ending 27th Sept 2024.   Bursaries available for a limited number of eligible participants (courtesy of the Centre for Environmental Research and Justice (CERJ), University of Birmingham).   This is a new and specialised course in the BMTC portfolio, aimed at PhD, Post-Doctorate and Early Career Researchers pursuing toxicological studies with metabolomics.   Through a combination of lectures, hands-on laboratory sessions and data analysis workshops (underpinned by a toxicological case study), participants will:  ⏺ Be introduced to the exciting field of metabolomics and learn how it can empower 21st century toxicological research, e.g.  - quantifying internal concentrations of chemicals in exposed biosystems   - exploring biotransformation products of exposure chemicals   - generating hypotheses relating to an exposure compound’s molecular mechanism(s)/mode(s) of action    ⏺ Explore experimental design principles that affect successful execution of metabolomics-based toxicology research and relevance of associated results.     ⏺ Learn the fundamentals of sample collection and extraction, gaining greater understanding of their importance in metabolomics data quality and content.     ⏺ Gain hands-on experience in setting up, calibrating and operating Thermo Scientific's Q Exactive Plus and Orbitrap Tribrid ID-X mass spectrometers, coupled with Vanquish liquid chromatography systems, for:   - full-scan LC-HRMS profiling of biological extracts - targeted analysis and quantification of exposure compounds  - tandem and multi-stage mass spectrometry analyses for annotation/identification of exposure compounds, biotransformation products and endogenous metabolites.      ⏺ Learn how to process and analyse metabolomics data, with a focus on toxicological applications and the associated challenges therein.  To find out more and register, please visit our website:   https://lnkd.in/dB-8_Zr8    #Metabolomics #Tox #Toxicology #LCMS #MassSpec #MassSpectrometry #ecotox #ecotoxicology

I’m excited to share that I'll be presenting my recent research in an upcoming webinar hosted by the Society of Toxicology's Computational Toxicology Specialty Section (CTSS). This opportunity follows my receipt of the CTSS Elsevier Student Award at the SOT Annual Meeting in Salt Lake City earlier this year—a recognition for which I’m incredibly grateful. Along with fellow award recipients, I will present my work tomorrow, November 14th, at 11:00 AM EST. My presentation is titled: "Predicting Chemical Immunotoxicity Through Data-Driven QSAR Modeling of AhR Agonism and Related Toxicity Mechanisms." You can register through the following link: https://lnkd.in/gWZGr6Hm. The study uses a data-driven modeling approach to predict immunotoxicity by leveraging the activation of the aryl hydrocarbon receptor (AhR) as a key immunotoxic pathway and identifying associated toxicity mechanisms. This research was also published in the ACS journal Environment & Health in May (https://lnkd.in/gGvxAqrg), and I’m excited to dive into the details and discuss its implications in the field of immunotoxicology. I look forward to meeting everyone! #toxicology #computationaltoxicology #research #webinar #immunotoxicity

🌟 Unlock the Future of Safety with Genetic Toxicology Services at Anthem Biosciences! 🌟 At Anthem Biosciences Private Limited, we understand the critical importance of genetic toxicology in drug development and safety assessments. Our specialized services are designed to help you navigate regulatory challenges while ensuring the safety and efficacy of your compounds. 🔬 Why Choose Our Genetic Toxicology Services? Expertise You Can Trust: Our team of experienced scientists employs state-of-the-art methodologies to deliver accurate and reliable results. Comprehensive Solutions: From in vitro assays to in vivo studies, we offer a full suite of services tailored to meet your project needs. Regulatory Compliance: We stay updated with global guidelines to ensure your studies meet the highest standards. Our Service Offerings: - Bacterial Reverse Mutation Test (AMES Test) - Enhanced AMES Test (EAT) - In Vitro Mammalian Chromosomal Aberration Test - In Vivo Mammalian Chromosomal Aberration Test - In Vitro Micronucleus Test - In Vivo Mammalian Erythrocyte Micronucleus Test - In Vivo Mammalian Alkaline Comet Assay Partner with us to safeguard your innovations and drive your projects forward with confidence! Let’s connect and discuss how our genetic toxicology services can support your research and development goals. Please visit our website: www.anthembio.com and/or reach out to our team at:bd@anthembio.com #AnthemBiosciences #GeneticToxicology #Biotech #SafetyAssessment #DrugDevelopment #Preclinical #CRO #OECD #EAT #Pharma #Agro #Toxicology #ERT #DABT #SOT #CAC #Nitrosamines #impurities Together, let's pave the way for a safer tomorrow!