Yesterday at IFPAC 2025, Jean-Marc Guedon discussed using continuous kLa and P/V modeling to improve bioprocess scaling. The study used Culture Biosciences’ 250 cloud-connected bioreactors and Gaussian Kernel Regression to scale a CHO process from 250mL to 5L, enhancing scaling strategies and optimization.Real-time scale-up metrics improve scale-down models, process development, and data-driven decisions. #Bioprocessing #CloudBioreactors #TechTransfer #IFPAC2025
