Corning Advanced-Flow Reactors’ Post

Chemical Essentials ⚗️ Whether you're advancing pharmaceuticals, materials science, or synthesizing natural products, the Wittig reaction is a classic and dependable method for converting aldehydes to alkenes.   For example, propyltriphenylphosphonium bromide (F222209) forms a phosphonium ylid when paired with a base. This then goes on to react with aldehydes to give the desired alkyne. 🧪 This particular phosphonium salt can also be used as an efficient phase-transfer catalyst for epoxidation reactions (converting alkynes to epoxides) and the carboxylation of epoxides – particularly styrene oxide (F227689, F223292, and  F221507).   At Fluorochem, we're here to support your research needs with high-quality reagents and expert support. Contact us to explore how we can help advance your projects. #Pharmaceuticals #Chemistry #MaterialsScience #Synthesis #Catalyst

Chemocatalysis has transformed industries such as pharmaceuticals, energy, and environmental technology. At Symeres, we routinely harness chemocatalysis to efficiently assemble complex molecules in a convergent and atom-efficient manner, resulting in cost-effective and eco-friendly synthetic processes. Our expertise includes: ·       Parallel experimentation for compound libraries ·       Late-stage functionalization for drug discovery ·       Advanced metal catalysis at the pilot-plant scale for manufacturing APIs for clinical trials With chemocatalysis, we achieve complex transformations, including the enantioselective creation of multiple chiral centers in a single step. Discover how we leverage chemocatalysis to drive innovation in drug discovery and beyond. Visit our webpage to explore our advanced capabilities. https://lnkd.in/dS6ekV8U #Chemocatalysis #Pharmaceuticals #CRO #Innovation #Symeres

💊 What does the future of pharma synthesis look like? Check out this recent publication which explores a novel method for synthesizing (3R)-quinuclidinol, a chiral building block in pharmaceutical products, using the integration of advanced catalysis. Together, Hydregen and AM Technology compare biocatalytic hydrogenation and metal-catalysed hydrogenation for ketone to chiral alcohol conversion, using the Coflore ACR. The use of a dynamically mixed flow reactor, precise temperature and flow rates enhanced the reaction's stability and scalability. Together, Hydregen and AM Technology leveraged the advantages of continuous flow chemistry and biocatalysis for sustainable manufacturing processes. 💡⚛️ Our publication shows promise of a scalable and efficient production of (3R)-quinuclidinol. View here > https://bit.ly/3PUOw1 #sustainability #pharmaceuticalindustry #pahrmaceuticalmanufacturing

Kudos to our researchers for their publication in the August issue of LCGC International! Chad Bastian, Alyssa McBurney, and Christopher Williams have shared their innovative work on Rapid Quantitative Analysis of Ethylene Oxide and 1,4-Dioxane in Polymeric Excipients Using SIFT-MS. Their research highlights the application of Selected Ion Flow Tube Mass Spectrometry (SIFT-MS) in the analysis of volatile compounds for the advancement of continuous pharmaceuticals manufacturing. Dive into our article here ➡️ <https://gag.gl/91WXU9> #LCGCInternational #SIFT-MS #continuouspharmamanufacturing #alcami

Kudos to our researchers for their recent publication in the August issue of LCGC International! Chad Bastian, Alyssa McBurney, and Christopher Williams collaborated on the paper titled Rapid Quantitative Analysis of Ethylene Oxide and 1,4-Dioxane in Polymeric Excipients Using SIFT-MS. Their work showcases groundbreaking efforts in utilizing Selected Ion Flow Tube Mass Spectrometry (SIFT-MS) for the analysis of volatile compounds in real-time, a significant advancement for continuous pharmaceuticals manufacturing. Dive into our comprehensive article here ➡️ <https://gag.gl/91WXU9> #LCGCInternational #SIFT-MS #continuouspharmamanufacturing #alcami

Stuck in a rut with your chemistry? Why not give #Symeres a call and see if our experienced and creative chemists cannot come up with a smart solution. Our team of expert chemists employs state-of-the-art techniques, such as cross-coupling and asymmetric #hydrogenation, to streamline the #synthesis of these complex molecules. This approach reduces time and costs, while increasing the yield of potential drug candidates. Additionally, our toolbox includes #parallelchemistry and #catalyst screening, which facilitate the rapid synthesis of analogues using the most suitable catalytic systems.

Ultradry™ high purity base metals and salts are the leading choice of pharmaceutical and electronic companies as the basic building blocks for many research and development processes. High Purity anhydrous halides are employed in numerous industries as Rare earth iodide inluminescence. Thermo Scientific ensures the quality and purity of each Ultradry™ product during manufacturing. Each Ultradry™ compound has a minimum purity of 99.99% (many exceed 99.999%). Know more: https://lnkd.in/dRYd3V2Z #ThermoScientific #HighPurityInorganics #MetalsMaterials #BaseMetals #Research #Academia #Pharmaceutical #MaterialScience #Electronics Pankaj Sharma I Anurag Tiwari I PREMAL VINCHHI I Rajat Padhi I Bidhan Dasgupta I Sourav Ghosh I Mohd Hashim Khan I Gulam Khader Khaise I Akhileshwar Kumar I Prabha N. I Sumit Pathare| Sohel Mohamed

🔬 #𝗤𝘂𝗮𝗻𝘁𝗶𝘁𝗮𝘁𝗶𝘃𝗲 𝗔𝗻𝗮𝗹𝘆𝘀𝗶𝘀 𝗨𝘀𝗶𝗻𝗴 #𝗥𝗮𝗺𝗮𝗻 #𝗦𝗽𝗲𝗰𝘁𝗿𝗼𝘀𝗰𝗼𝗽𝘆 𝗶𝗻 𝗣𝗵𝗮𝗿𝗺𝗮𝗰𝗲𝘂𝘁𝗶𝗰𝗮𝗹 𝗔𝗽𝗽𝗹𝗶𝗰𝗮𝘁𝗶𝗼𝗻𝘀 💊https://horiba.link/m1y Check out the Raman spectra of DayQuil™ and NyQuil™ collected with an immersion probe fiber-coupled to the MacroRAM™ Raman spectrometer. 📈🔍 While Raman spectroscopy is renowned for qualitative chemical analysis, did you know it can also excel in quantitative analysis? 🌟 Here’s how: Versatile Conditions: Effective for various solutes and solution mixtures. #Pharmaceutical Applications: Perfect for analyzing content uniformity in pharmaceuticals. With our advanced MacroRAM™ Raman spectrometer and immersion probe setup, we demonstrate how Raman spectroscopy can revolutionize quantitative analysis in pharmaceuticals. 🚀🔬

Really excellent collaboration to get to this result! Kudos to our researchers for their publication in the August issue of LCGC International! Chad Bastian, Alyssa McBurney, and Christopher Williams collaborated on the paper titled Rapid Quantitative Analysis of Ethylene Oxide and 1,4-Dioxane in Polymeric Excipients Using SIFT-MS. Their work showcases cutting-edge advancements in utilizing Selected Ion Flow Tube Mass Spectrometry (SIFT-MS) for the analysis of volatile compounds in real-time, significantly benefiting continuous manufacturing in the pharmaceutical sector. Dive into the full article here ➡️ <https://gag.gl/91WXU9> #LCGCInternational #SIFT-MS #continuouspharmamanufacturing #alcami

工作坊預告 -- Accelerate your Pharmaceutical and Materials Research with CAS SciFinder Discovery Platform   明天在線上參加SciFinder工作坊吧！ ·        時間為下午15:00-16:30 ·        工作坊為線上課程 ·        工作坊會以英語教學   Content: • Learn new Reference searching tips using Precision Search and Boolean operators. • Explore CAS Lexicon for Pharmaceutical and Material Science topics. • Plan multi-step synthesis with Retrosynthetic Analysis for known and novel compounds. • Find the best research protocols for material analysis, synthesis, bioassays and formulations. • Use visualization tools for trends analysis.   立即點擊連結報名參加吧！ https://lnkd.in/g2pgRFXs