“Right from the moment I met Wes, I knew he was someone I wanted to work with. He's thoughtful, perceptive & considered, qualities which are clearly helping him to be a valued product leader. One of the biggest things which struck me is his ability to give and take feedback in a way which is healthy and constructive, both for his own professional growth and for his product. By being open-minded and eager to learn, Wes is able to use the information around him to ensure positive change. If you have the opportunity to work with Wes, you should jump at it! ”
About
Hi, I'm Wes! I'm a data-driven product leader with 10+ years of SaaS product management…
Contributions
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What are the best ways to use lean methodology for managing your team's workload?
In my experience, this is where so many teams fall short: they wait until the end to "Learn". In a Build-Measure-Learn cycle, it's critical to start with the Learn step. Do some generative, discovery work to ensure you're starting from a data-informed position rather than an opinion-driven one. "Learning velocity", how quickly a team can learn & iterate, is a great indicator of team's ability to continuously improve.
Activity
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🗓️ Mark your calendars! Our Chief Product Officer, Brandon Rice, joins JP Valentine on The Alldus Podcast: AI in Action next Monday! 🎙️ Brandon…
🗓️ Mark your calendars! Our Chief Product Officer, Brandon Rice, joins JP Valentine on The Alldus Podcast: AI in Action next Monday! 🎙️ Brandon…
Liked by ✟Wes Galliher, Ph.D.
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Don't miss next Monday's brand new episode in our AI in Action series of The Alldus Podcast when host JP Valentine will be joined by Brandon Rice…
Don't miss next Monday's brand new episode in our AI in Action series of The Alldus Podcast when host JP Valentine will be joined by Brandon Rice…
Liked by ✟Wes Galliher, Ph.D.
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"Customer-driven" isn't just a value that goes on a poster on the wall in Weave's virtual office (we're a fully remote company), we live it. This…
"Customer-driven" isn't just a value that goes on a poster on the wall in Weave's virtual office (we're a fully remote company), we live it. This…
Shared by ✟Wes Galliher, Ph.D.
Experience
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Education
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Stanford University
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Activities and Societies: Health Care Club (Stanford Business School), Liaison for student-led Stanford Association for Multidisciplinary Medicine and Science, Teaching Assistant for Undergraduate Lab and Lecture Courses
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Activities and Societies: Phi Kappa Phi, Chemistry Club, Intramural sports (basketball, volleyball, tennis), Potter's Clay Mexico Mission Trip, Gospel Choir, Chamber Singers
Volunteer Experience
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Vice President Board of Directors ('20-'22) and Director of Volunteers ('17-'19)
ProductCamp Dallas
- 4 years 11 months
**Organization Homepage:** https://productcampdallas.org
- Created & refined vision & mission of ProductCamp Dallas
- Developed & helped execute strategy for biannual "unconference" events for product managers, designers, developers, and researchers
- Increased engagement of both online & offline community of local product people
- Recruited, trained, and coordinated day-of-event activities for more than 15 volunteers to ensure a smooth Spring event
- Supported and managed…**Organization Homepage:** https://productcampdallas.org
- Created & refined vision & mission of ProductCamp Dallas
- Developed & helped execute strategy for biannual "unconference" events for product managers, designers, developers, and researchers
- Increased engagement of both online & offline community of local product people
- Recruited, trained, and coordinated day-of-event activities for more than 15 volunteers to ensure a smooth Spring event
- Supported and managed efforts to attract and close 8 Spring event sponsors across 3 sponsorship tiers -
Product Workshop Trainer
Mind the Product
- 1 year 4 months
Science and Technology
**Workshop Info** https://www.mindtheproduct.com/product-management-training/
- Led in-person training sessions for product managers to learn, apply, and practice foundational principles, mindsets, and strategies of product management.
- Led advanced sessions on applying strategic approaches to the tactical elements of product management in order to communicate & align the entire organization around product vision and process. -
Fast Start Mentor
The DEC Network
- 2 years 1 month
Mentor to local entrepreneurs and small business owners, helping them simplify complex challenges, generate insights from customer research activities, and devise strategies to achieve their business goals
Program Details: https://thedec.co/programs/ -
Deacon Board Member (2019 Board Chairman)
Grace Bible Church
- 3 years
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Youth Ministry Volunteer
Grace Bible Church
- 3 years 11 months
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Worship Team Volunteer
Grace Bible Church
- 2 years 4 months
Play in the worship band on piano and/or tenor vocals
Publications
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Taxol-Oligoarginine Conjugates Overcome Drug Resistance in-vitro in Human Ovarian Carcinoma
Gynecologic Oncology
Multidrug resistance is the major cause of failure of many chemotherapeutic agents. While resistance can arise from several factors, it is often dominated by drug efflux mediated by P-glycoprotein (P-gp), a membrane-bound polysubstrate export pump expressed at high levels in resistant cells. While co-administration of pump inhibitors and a drug could suppress efflux, this two-drug strategy has not yet advanced to therapy. We recently demonstrated that the reversible attachment of a…
Multidrug resistance is the major cause of failure of many chemotherapeutic agents. While resistance can arise from several factors, it is often dominated by drug efflux mediated by P-glycoprotein (P-gp), a membrane-bound polysubstrate export pump expressed at high levels in resistant cells. While co-administration of pump inhibitors and a drug could suppress efflux, this two-drug strategy has not yet advanced to therapy. We recently demonstrated that the reversible attachment of a guanidinium-rich molecular transporter, polyarginine, to a drug provides a conjugate that overcomes efflux-based resistance in cells and animals. This study is to determine whether this strategy for overcoming resistance is effective against human disease.
Other authors -
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The Design of Guanidinium-Rich Transporters and Their Internalization Mechanisms
Advanced Drug Delivery Reviews
The ability of a drug or probe to cross a biological barrier has historically been viewed to be a function of its intrinsic physical properties. This view has largely restricted drug design and selection to agents within a narrow log P range. Molecular transporters offer a strategy to circumvent these restrictions. In the case of guanidinium-rich transporters (GRTs), a typically highly water-soluble conjugate is found to readily pass through the non-polar membrane of a cell and for some across…
The ability of a drug or probe to cross a biological barrier has historically been viewed to be a function of its intrinsic physical properties. This view has largely restricted drug design and selection to agents within a narrow log P range. Molecular transporters offer a strategy to circumvent these restrictions. In the case of guanidinium-rich transporters (GRTs), a typically highly water-soluble conjugate is found to readily pass through the non-polar membrane of a cell and for some across tissue barriers. This activity opens a field of opportunities for the use of GRTs to enable delivery of polar and non-polar drugs or probes as well as to enhance uptake of those of intermediate polarity. The field of transporter enabled or enhanced uptake has grown dramatically in the last decade. Some GRT drug conjugates have been advanced into clinical trials. This review will provide an overview of recent work pertinent to the design and mechanism of uptake of GRTs.
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Recommendations received
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LinkedIn User
5 people have recommended ✟Wes
Join now to viewMore activity by ✟Wes
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Creation of documents (like regulatory submissions) with LLMs is like going from line cook to head chef. Rather than spending all day peeling…
Creation of documents (like regulatory submissions) with LLMs is like going from line cook to head chef. Rather than spending all day peeling…
Liked by ✟Wes Galliher, Ph.D.
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Special shout out to everyone who engaged with us at #DIA #RSIDM25! If you left wanting more, there’s a lot to review and expand on ✔️Weave platform…
Special shout out to everyone who engaged with us at #DIA #RSIDM25! If you left wanting more, there’s a lot to review and expand on ✔️Weave platform…
Liked by ✟Wes Galliher, Ph.D.
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