Kaylee Mueller

Why do I work for Bio-Rad? We launch innovative products that help advance therapeutics for cancers and rare diseases, making a real impact on healthcare. Check out this article featuring Dr Chelsea Pratt on how we’re helping drug developers optimize gene therapies by simplifying the quantification of empty/full AAV capsids.

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Join Joanne Meister, MS, CGC at #AHIP2024 for an update on the most current genetic testing issues making waves for health plan leaders, with associated strategies for efficient, cost-effective UM to come out ahead. #BiomarkerMandates #ClinicalUtility #PLAcodes #FDA #GeneticTesting #UtilizationManagement

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A PCR evolution ? No a PCR Revolution. Now you can Type a Salmonella or Listeria monocytogenes, Now you can identify pathogens clusters, Now you can conduct a Pathogen root cause with a simple PCR equipment in 1h…. Now you know ! Now bioMerieux

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Exciting news coming out of AMP 2024: Announcing a strategic partnership and presentation with Agena Bioscience to bridge critical gaps in detecting mutations not identified by next-generation sequencing (NGS) alone. https://hubs.ly/Q02YV4vF0 #AMP #next-generation sequencing

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Check out this rapidmicrobiology.com article that discusses rapid methods for ensuring the microbiological safety of short-life cell and gene therapeutics, as well as the importance of bioburden testing. It also introduces the Milliflex® Rapid System 2.0 as a single platform for both rapid sterility and rapid bioburden testing, offering easier validation and implementation. Chinmay A. DESHPANDEVeena PriyadarshiniAnirudha KulkarniRavinder Singh JaswalDinesh RaveendrarajuParag VachhaniHarmesh Sahay, PhDJanice GoveasMerck Life Science

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Check out this rapidmicrobiology.com article that discusses rapid methods for ensuring the microbiological safety of short-life cell and gene therapeutics, as well as the importance of bioburden testing. It also introduces the Milliflex® Rapid System 2.0 as a single platform for both rapid sterility and rapid bioburden testing, offering easier validation and implementation. Veena PriyadarshiniChinmay A. DESHPANDEAnirudha KulkarniRavinder Singh JaswalParag VachhaniDinesh RaveendrarajuHarmesh Sahay, PhDJanice GoveasMerck Life Science

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Don't miss this upcoming webinar on Sept. 11! Dive into the latest advancements in multiplex assay technology with #xMAP INTELLIFLEX® DR-SE! The system allows for rapid data acquisition across multiple parameters, boosting lab efficiency by processing up to 500 targets in a single well. You'll hear from from Dr. Ronald Backer (Luminex ) on the fundamentals and Dr. Wim Dik (Erasmus Medical Center) with real-world insights on adapting these assays. #Multiplexing #ResearchInnovation #xMAPINTELLIFLEX Bitesize Bio

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Learn more from our Eureka Blog about innovative research being done to develop better in vitro techniques for studying so-called mechanical diseases, like hypertension or arrhythmias. https://okt.to/6Hhag8

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Exciting news coming out of AMP 2024: Announcing a strategic partnership and presentation with Agena Bioscience to bridge critical gaps in detecting mutations not identified by next-generation sequencing (NGS) alone. https://hubs.ly/Q02YV2-10 #AMP

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Happy Thursday all! Check out this open access Nature Leukemia review by Lei et al., "Leveraging CRISPR gene editing technology to optimize the efficacy, safety and accessibility of CAR T-cell therapy." https://lnkd.in/gAWFHq-j. Abstract: Chimeric Antigen Receptor (CAR)-T-cell therapy has revolutionized cancer immune therapy. However, challenges remain including increasing efficacy, reducing adverse events and increasing accessibility. Use of Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR) technology can effectively perform various functions such as precise integration, multi-gene editing, and genome-wide functional regulation. Additionally, CRISPR screening using large-scale guide RNA (gRNA) genetic perturbation provides an unbiased approach to understanding mechanisms underlying anti-cancer efficacy of CAR T-cells. Several emerging CRISPR tools with high specificity, controllability and efficiency are useful to modify CAR T-cells and identify new targets. In this review we summarize potential uses of the CRISPR system to improve results of CAR T-cells therapy including optimizing efficacy and safety and, developing universal CAR T-cells. We discuss challenges facing CRISPR gene editing and propose solutions highlighting future research directions in CAR T-cell therapy. #drugdiscovery #cancerresearch #crispr #tcelltherapy #immunooncology #immunotherapy #scientificresearch

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🚀 Exciting News for Biocom California Members! 🚀 Your fellow member, Transition Services, Inc. (TSI), is hosting a game-changing, hour-long webinar on July 16th, 2024, at 11:00 AM PST that you will not want to miss! Discover a little-known separation benefits structure that can drastically cut your company's costs while providing an innovative alternative to traditional severance. 💡 𝐖𝐡𝐲 𝐀𝐭𝐭𝐞𝐧𝐝? 𝟏. 𝐈𝐧-𝐝𝐞𝐩𝐭𝐡 𝐔𝐧𝐝𝐞𝐫𝐬𝐭𝐚𝐧𝐝𝐢𝐧𝐠: Learn about SUB Plans, an IRS-sanctioned and tax-advantaged alternative to severance. 𝟐. 𝐋𝐞𝐠𝐚𝐥 𝐚𝐧𝐝 𝐓𝐚𝐱 𝐈𝐧𝐬𝐢𝐠𝐡𝐭𝐬: Understand the benefits associated with SUB Plans. 𝟑. 𝐈𝐦𝐩𝐥𝐞𝐦𝐞𝐧𝐭𝐚𝐭𝐢𝐨𝐧 𝐒𝐭𝐫𝐚𝐭𝐞𝐠𝐢𝐞𝐬: Discover how to implement this flexible and cost-effective severance alternative. 𝟒. 𝐍𝐞𝐭𝐰𝐨𝐫𝐤𝐢𝐧𝐠 𝐎𝐩𝐩𝐨𝐫𝐭𝐮𝐧𝐢𝐭𝐢𝐞𝐬: Expand your professional network. Click the link below for more details and to secure your spot for this must-attend virtual event. Do not miss out on the opportunity to revolutionize your approach to employee separations! #employeeseparations #severancealternative #hrbenefits #supplementalunemploymentbenefits #costsavings #strategicplanning

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Whether you are considering, new-to, or experienced in Next-Generation Sequencing #NGS you may be interested to learn or have a refresh on, How to Plan Your First Sequencing Project. Register to gain insights to enhance your sequencing projects. Register here 👉 https://lnkd.in/gaZ74HpT Hear from the expert, Anthony AlKhoury, Senior Technical Applications Scientist at Illumina who will cover all the foundational aspects of starting a sequencing project; including experimental design, sample selection, and data requirements followed by a detailed exploration of library preparation techniques. Anthony will also guide you through the sequencing process, discussing platform selection, run parameters, and quality control measures to ensure the best possible results. But wait...there's more...Anthony will also delve into data analysis, covering everything from basic alignment to advanced bioinformatics pipelines, equipping you with the tools to extract meaningful insights from your sequencing data.

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Do you know when companion diagnostics (CDx) are needed for your cell and gene therapy programs? Or what kind of testing is required and how to choose the right lab partner for a CDx assay? In our blog, you’ll learn from Labcorp subject matter experts as they answer key questions you may have about developing CDx for your cell and gene therapy programs. Learn more: https://lnkd.in/gSChJieM #CellandGeneTherapy #CompanionDiagnostics

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We are thrilled to share the presentation of Stephanie Chrysanthou, PhD, our R&D Manager at Integrated Genomics Operation Memorial Sloan Kettering Cancer Center, on detection of germline alterations in solid #cancer patient samples by adaptive sampling 🙌 presented at the Nanopore Community Meeting conference in Boston! Our core has closely partnered with the Molecular Pathology & Diagnostics lab to benchmark Adaptive Sampling long read #sequencing for detecting germline #mutations against prior MSK-IMPACT profiles generated by hybridization capture short-read sequencing. Adaptive Sampling is a promising approach due to reduced technical complexity and TAT, there is no need for sample batching and it facilitates the resolution of large complex structural #variants. Due to the live #basecalling capacity of the #nanopore technology, the sequencing can be stopped if a fragment does not match the uploaded target .bed file, thus enriching on-target fragment #sequencing. Briefly, our on-instrument data workflow includes: 1) filtering of the raw .pod5 files based on the on-target decision, 2) SUP basecalling, 3) GRCh38 alignment, 4) SNV/SV calling using #EPI2ME and #SEVERUS pipelines.  On a routine basis, this workflow, from #hmwDNA extraction to data analysis, takes 3.5 days. Feel free to watch the full presentation here 👇 (it's free to register and you'll get access to all ONT conference presentations!) Oxford Nanopore Technologies https://lnkd.in/ezE_vsYT

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In today's complex bioprocessing landscape, optimizing downstream purification is crucial for developing next-generation biotherapeutics. The challenges of enhancing productivity while reducing costs are more pressing than ever. Join Andy Masters and Mark Hicks for an insightful webinar: "Addressing the Challenges of Complex Biologic Purification: New Advances in Protein A Affinity Resins" In this session, we'll explore: ⚪ The evolving landscape of protein A chromatography resins 🤝 How strategic partnerships are driving technology innovation 🔀 Discover how our new DurA Cycle™ A50 can increase productivity and reduce costs through improved stability and low ligand leakage 📈 Performance data from Ecolab's wider protein A toolbox resins Register below: https://lnkd.in/eAATMaMw

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