John Hall

Having a Cars and Capital event tomorrow in Southern California with Oren Klaff. If you want to join message me. https://lnkd.in/gDQ4D39u Oren Klaff Bridger Pennington #InvestorEvent #FamilyOffice #InvestmentOpportunity #CarlsbadEvent #PrivateEquity #WealthManagement #InvestmentConference #CapitalRaising #NetworkingEvent #IndustryLeaders #FinancialGrowth #InvestorsMeetup #WealthBuilding #BusinessGrowth #InvestmentForum

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AI and Med Tech in Focus   AI System Developed to Identify Pathology in Tissues Engineers at Washington State University have developed an AI tool that uses images of human and animal tissue to detect abnormalities faster and more accurately than people. The AI algorithm was trained using images from past studies that involved kidney, testes, ovarian, prostate, breast and lymph node abnormalities. The new model detected disease in minutes—current processes take humans several hours and require specialized teams to check each other’s work. It was also found to be more accurate, sometimes detecting instances that humans had missed. The engineers designed the system to handle the processing load of the high-resolution gigapixel images by breaking them down into smaller tiles but still retaining the overall context of the tissue sample—akin to the zoom feature on a microscope or phone camera. Aside from getting diagnostic results more accurately and quickly, the new system also shows promise in epigenetics (the study of molecular processes that change gene behavior without changing underlying DNA). Epigenetic researchers can perform analyses and get results that used to take a year or more in just a couple of weeks. VC Investors are always adjusting their "Play Book" with a variety of options for investing. Mikal Ventures is one of those alternatives, offering curated solutions to real world problems. Reach out if you have questions on how we can be of assistance and bookmark https://mikalventures.com/ for additional insights and information.

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As we get prepared for our Angel Conference program, we run workshops to help get things lined up for the right conversations between investors and early pre-seed startups. We have a deadline coming up on August 27th for startups. One of the places that we see companies having a bit of trouble is on the customer discovery side of things. So we have a couple of workshops on that early customer discovery and associated efforts to get traction early before your MVP. As Angel Investors, we need to think with a portfolio mindset instead of investing in one or two companies to "see how it goes". We have a panel of SAC alumni talking about their perspectives on their portfolio of companies. We also know that startups don't practice pitching enough. So we we have workshops for improving pitches before people pitch for real. You can see the upcoming workshops here: AI+Lean  Building automated content experiments for customer discovery Tuesday, August 6, 2024 10:00 AM to 12:00 PM PDT https://lnkd.in/gJMiyQZC Building Your Angel Investment Portfolio Tuesday, August 6, 2024 6:00 PM to 8:00 PM PDT https://lnkd.in/gD9ATSyG Pitch Deconstruction and Review Thursday, August 8, 2024 12:00 PM to 2:00 PM PDT https://lnkd.in/g-RRajrX Finding your first paying customers Tuesday, August 13, 2024 10:00 AM to 12:00 PM PDT https://lnkd.in/gN-DaRJ8 Angel Investing and Taxes Thursday, August 15, 2024 12:00 PM to 2:00 PM PDT https://lnkd.in/gjs9cQfy Solving Real Problems: The Key to Market Success Tuesday, August 20, 2024 10:00 AM to 12:00 PM PDT https://lnkd.in/gYkJFD-X Structuring a Pitch Deck That Engages Investors Thursday, August 22, 2024 12:00 PM to 2:00 PM PDT https://lnkd.in/geyYR4wB Seattle Angel Conference (SAC 26) Application Deadline Tuesday, August 27, 2024 9:00 PM to 9:05 PM PDT  (But REALLY … Apply early)  https://lnkd.in/gM_fSmbZ  Companies need to apply here - https://lnkd.in/gWbtkAaf Please let the folks around you know about these workshops.

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At Two Bear Capital our definition of value-add, lead, early-stage investing is to form a true partnership with the founders we back. We believe that only a small fraction of our return potential comes from us “picking right” when we make our first investment into a company – the vast majority comes from how effectively we can actively help our brilliant founders over the ensuing 3-7 years in achieving the passionate, ambitious, and positive-impact goals that drive them.

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Friends, Q2 was a quarter of progress and learning for us at HawkTower, where we invest in early-stage startups applying breakthrough computing technologies to maximize California's natural resource markets. Our focus is on technology-enabled interventions (e.g., AI-enabled geospatial radars for lithium-ion batteries in the waste stream) for critical, market-level imperatives (e.g., disaster prevention) that can drive rapid commercial adoption (e.g., placed on every recycling truck in the world). Our current investment priorities are: - Agricultural productivity and efficiency - Biomanufacturing - Labor and mobility automation - Waste stream optimization and decarbonization - Disaster prevention and management Here’s a snapshot of what we’ve been up to: Milestones and Investments: - In late April, we officially launched our fund, filing with the SEC. Yay. - By June, we completed our first fund close ahead of schedule, with backing from family offices, foundations, high-net-worth individuals, and organizations aligned with California's future. - Our portfolio now includes three early-stage investments (Farm-ng, Agriful Software, and Nexstera Tech). Strategic Partnerships: - We believe that startups operating closer to their customers and resources, especially in agriculture and biomanufacturing, have a strategic advantage. For instance, the Salinas Valley, a major agricultural hub, is less than an hour from Silicon Valley and serves as a center of thought leadership in the convergence of agriculture and AI (from Western Growers, Taylor Farms, and others). - Similarly, the North San Joaquin Valley is emerging as a biotech and agtech innovation hub, and we are proud to support BEAM Circular, a startup hub for the circular bioeconomy. Key Relationships: - Karen Warner, CEO of BEAM Circular, joined HawkTower as a strategic advisor. - Jackie Cruz, Ed. D. Cruz, Hartnell College’s VP of Advancement, advises on Salinas Valley and workforce development. - Ben Palone from Western Growers, with his technical background in agriculture, became a trusted advisor. - Matthew Hoffman from Driscoll's Global R&D team provides insights on global agriculture, product positioning, and investment strategy. - We collaborated with Monterey Bay DART for workforce development and automation in agtech. - Dominic Milano and the Milano Technical Group from Merced collaborated on key initiatives and advised us on investments. - HawkTower is participating in Santa Cruz Works's accelerator cohort as a mentor and advisor. Thank you Doug Erickson. - We published an overview of entrepreneurship across the UC system with input from across the University of California system. Moving into the fall, we remain deeply committed to supporting founders shaping California's future natural resource markets. Stay tuned and be in touch! : ) Db

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If you work in tech transfer this is a good read-in on how our diligence tech can assess and evaluate assets with minimal inputs. The best way to learn more is to see it live! Reach out to me directly to learn more!

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AI and Med Tech in Focus   AI System Developed to Identify Pathology in Tissues Engineers at Washington State University have developed an AI tool that uses images of human and animal tissue to detect abnormalities faster and more accurately than people. The AI algorithm was trained using images from past studies that involved kidney, testes, ovarian, prostate, breast and lymph node abnormalities. The new model detected disease in minutes—current processes take humans several hours and require specialized teams to check each other’s work. It was also found to be more accurate, sometimes detecting instances that humans had missed. The engineers designed the system to handle the processing load of the high-resolution gigapixel images by breaking them down into smaller tiles but still retaining the overall context of the tissue sample—akin to the zoom feature on a microscope or phone camera. Aside from getting diagnostic results more accurately and quickly, the new system also shows promise in epigenetics (the study of molecular processes that change gene behavior without changing underlying DNA). Epigenetic researchers can perform analyses and get results that used to take a year or more in just a couple of weeks. VC Investors are always adjusting their "Play Book" with a variety of options for investing. Mikal Ventures is one of those alternatives, offering curated solutions to real world problems. Reach out if you have questions on how we can be of assistance and bookmark https://mikalventures.com/ for additional insights and information.

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Startup Founders: here is a SUPER interesting list of emerging and first-check VC firms, many of them new or under-the-radar. Why should you care? Because... 1) emerging VCs are often easier to get in front of and, 2) since they are still building their track record, they will often hustle harder to make your startup a success. (Excellent work, Anne Gherini! :) #startups #venturecapital #entrepreneurship

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Faster inference is on the way.

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👀 Looking at our recent investments at Draper Associates, here’s what standout founders nailed, making our decision to invest much easier (and faster): 💥 Visionary Tech with a Bold Vision – These founders are not here for incremental wins; they’re reimagining what’s possible in across tech - biotech, robotics, aerospace, and beyond. Their vision is big and audacious, tackling complex problems that demand breakthrough solutions, others have not been willing to try. 👊 Clear Passion & Purpose – The drive in these founders is undeniable. They’re committed to their mission with a depth of purpose that shapes every choice. One founder, for example, took two years completely off to learn and meet everyone in longevity biotech. This level of grit and dedication is rare but essential for the most impactful founders. 🌟 Assembling All-Star Teams – They bring together top-tier talent from diverse disciplines: experienced business leaders with successful exits or industry experience at top companies, technical co-founders with deep expertise, often PhDs or industry pioneers, and even published authors. It’s a complementary team, unified by a shared vision. They make the: "Why this team?" obvious - at a glance. 💻 Data-Driven to the Core – These founders present data insights that show why their approach is unique, especially against a competitive field of companies. This data is delivered with clarity and they make the complex simple. Many are published in top journals, adding depth and credibility to their approach, and reinforcing that they know their tech inside out. ⚡️ Memorable, Clear Vision – They don’t just pitch; they make the future feel tangible, with a vision that’s both compelling and concise. If I can relay their pitch in under 30 seconds to my team, they’ve killed it. 📣 Transparent & Proactive Communication – The best founders don’t wait for questions. They come prepared, often with a comprehensive FAQ doc, give timely updates to our questions, and are candid about challenges. This level of openness builds trust and strengthens our partnership. 💸 Milestone-Driven Funding Strategy – Each funding stage aligns clearly with already achieved or upcoming achievable milestones. They’ve mapped out a roadmap that minimizes risk at every step, giving us confidence in their journey. 💰 Revenue Milestones Along the Way – Even if it'll take a decade to hit revenue on their big vision, these founders find revenue generation stops along the way to profitability. They share a trajectory that connects early wins to revenue, showing how every step is a building block toward their bigger vision. Overall, the best founders are incredibly thoughtful, prepared, and fantastic verbal / written communicators. #founders #startups #fundraising #VC

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https://lnkd.in/dDGfRVai "The amendments can be broken down into five core components, and while they don’t actively advance the fortunes of AI companies, they do make their lives easier. For example, one amendment will replace criminal penalties for perjury with civil ones, meaning the act now invokes no criminal charges for any violation and the legal repercussions of stepping out of line are significantly reduced.  The amended bill now also cuts the Attorney General’s ability to seek civil penalties “unless a harm has occurred or there is an imminent threat to public safety.” The amended bill makes the Attorney General’s office the main regulatory body for AI, rather than an originally proposed state regulatory body."

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VC Market Update: Riding Out the Post-Boom Bumps. 2021's high-flying valuations and growth have given way to a more complex reality. With longer private timelines, tough exit markets, and capital tightness, startups face unique challenges—but also fresh opportunities. For those navigating today’s VC landscape, strategic planning is key. Whether it's balancing growth with capital efficiency or exploring secondaries smartly, there’s a path forward. And with boosts from AI and future rate cuts, brighter days could be ahead!

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Check out our newest portfolio company - helping to accelerate quantum innovation

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🐺🚨🚀Three years ago, we launched Pack Fund I. Today, we launch Fund II with some big news from U.W.!🚨🚀🐺 We are now a Preferred Venture Partner of the University of Washington and CoMotion at University of Washington! After three years of hard work, during which we backed 29 startups, mentored on campus, and sponsored entrepreneurship clubs and competitions in the UW Foster School of Business and Paul G. Allen School of Computer Science & Engineering, we are thrilled to be taking our collaboration with U.W. to the next level! On the back of this news and early successes, we are hosting a webinar for accredited and interested L.P.s to learn about joining Fund II - https://lu.ma/pbwih7xa What Is the Latest On Fund I? - 26 companies backed in 3 years - 12 have raised additional funding at higher valuations - $135M+ in additional funding and grants - Invested alongside Madrona, FUSE, Khosla Ventures, Y Combinator, Pioneer Square Labs, Trilogy Equity Partners, Cercano, Washington Research Foundation, and dozens of other top investors. - Supported founders in Software, Life Sciences - Recognized as a top 5 most active life science investor in the PNW in 2022 - 80+ L.P.s supported our vision How is Pack Fund II Starting? - Ti Zhao joined full-time - let's go!!!! - Agreement (M.O.U) signed with U.W., making us a preferred venture partner - 2 investments alongside top VCs - 50+ L.P.s already joined - Fund II is larger than Fund I already - Hundreds of companies reviewed already See the news from U.W. here -https://lnkd.in/girhA3BM GeekWire and Taylor Soper covered our vision masterfully here - https://lnkd.in/gHYFAxzY Thanks to all of the Pack members and founders who have been on this journey with us!

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14 SiliconXL / DevAccelerator Powered Startups Launch in Stealth Providence, RI - Tuesday, September 24th The SiliconXL Startup Demo Day brought together a remarkable collection of AI-powered tech startups, demonstrating that the event was about far more than just polished pitch decks—it was a showcase of full-stack software engineering, AI, true innovation and customer-validated market demand. DemoDay Startups - Providence took place during RI Startup Week, with tremendous support from RIHub. Each startup, built from the ground up by technical founders, presented AI-driven solutions designed to solve real-world problems. This event emphasized the importance of market fit, with every startup validating their concept through direct interaction with potential users, showcasing not only their technical prowess but their ability to engage with and fulfill market needs. For many of the entrepreneurs showcased at the SiliconXL Startup Demo Day, this was their first experience building a full-stack application. In fact, virtually none of them had ever launched or scaled a tech startup before. Their journey from novice to technical founder was nothing short of transformative, a direct result of their time learning software engineering and AI under the mentorship of Claude Arnell Milhouse and Clifton Choiniere at DevAccelerator. Through DevAccelerator's intensive training and guidance, these founders have not only acquired the technical skills to develop cutting-edge AI solutions but have also gained the entrepreneurial mindset to launch and grow successful startups. This Demo Day is a testament to the profound impact that mentorship, education, and determination can have on an individual's ability to create something that will disrupt industries and transform their own lives in the process. What set this Demo Day apart was the potential for explosive growth, as SiliconXL is laser-focused on launching a tidal wave of startups across multiple markets in the upcoming months and years. From the buzzing streets of Boston and New York to the previously unknown startup market of Providence, the goal is clear: to create a tsunami of high-growth startup activity.  SiliconXL is also dedicated to ensuring that diverse communities not only have a seat at the table but are also leading the charge, amplifying voices that have been historically marginalized. With this Demo Day, it’s evident that SiliconXL is igniting a movement that will leave a lasting mark on the future of AI-powered innovation. Look for more events powered by DemoDay Startups in the months to come in a city near you (Hint: Boston, NYC and up to 16 more startups out of Providence this year). Let's GEEEEEKING Goooooo!!!! #Startups #TechnicalFounders #SoftwareEngineers #Providence #Boston #NewYork #Roxbury #Dorchester #Brooklyn #Queens #TheBronx #Harlem

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San Diego investor event: Aquillius Medical Devices & Diagnostics Symposium, taking place on Wednesday, May 15th, from 12:30 PM to 7:00 PM. This exclusive event brings together leading industry experts, groundbreaking startups, and prominent investors like yourself. Here's what you can expect: Expert Insights: Gain valuable knowledge from renowned speakers on topics critical to medtech success, including design for manufacturing, intellectual property protection, regulatory navigation, and fostering successful startups. Early Access to Innovation: Witness the future of healthcare firsthand as promising Aquillius incubees showcase their innovative medical device and diagnostic solutions during a dedicated startup showcase. Networking Opportunities: Connect and build relationships with other investors, entrepreneurs, and industry leaders shaping the medical technology landscape. This is a unique opportunity to: Identify promising investment opportunities in the medtech sector. Gain valuable insights from leading experts. Network with a community of like-minded investors and industry professionals. Space is limited, so RSVP today! Medical Devices Symposium (Investor Registration) Tickets, Wed, May 15, 2024 at 12:30 PM | https://lnkd.in/gjWDU9pz

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A big part of making AI usable is enabling testing to provide the necessary assurance that outputs make sense. Distributional is leading this capability.

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Our partner Eddie Eltoukhy has identified these opportunities in Biotech. Eddie has a PhD in bioengineering from Massachusetts Institute of Technology and over a decade experience as an operator. Reach out to him if you are working on these areas of biotech. Pear VC - Technology-Driven Therapeutic Platforms Companies developing therapeutic assets with a core product engine Proprietary tool, workflow, or samples leading to novel biological data sets Preference for omics platforms or high throughput screening / engineering workflows First-in-class or best-in-class drugs - Next-Generation Therapeutic Modalities Technologies to improve the efficacy, safety, access, or reach of next-gen modalities including the following: Genomic medicines (gene tx & gene editing) Cell therapies Targeted protein degraders Antibody-drug conjugates Radiopharma - Precision Medicine New technologies supporting the discovery of novel biomarkers and the generation of proprietary data sets for applications in: Disease screening Therapy selection Recurrence monitoring - Life Sciences + AI Software Platforms Software & AI-driven platforms to improve all aspects of life sciences R&D, including: Target discovery and validation Drug design and optimization Manufacturing Regulatory Clinical development

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