Biomedical Data Science Innovation Lab

Join us on Friday, 2/28 at 12-1 PM ET for our next seminar: Single-Cell Multi-Omics of Fetal Blood Development in Humans presented by Andrew Marderstein, PhD from Memorial Sloan Kettering Cancer Center! https://lnkd.in/dEWMqAZF Children with Down Syndrome, caused by an extra copy of chromosome 21, face a staggering 150-fold higher risk of leukemia by age 5, with early blood abnormalities already present by birth. But why do these health challenges, including heightened cancer risk, occur? By analyzing over 1 million single cells through multi-omics technologies—including scRNA-seq, multiome (paired scATAC-seq and scRNA-seq), and spatial transcriptomics— Dr. Marderstein's team have created the most detailed map yet of fetal blood development. This data reveals how inherited genetic changes reshape blood cell development, setting the stage for cancer before any cancer-driving mutations emerge. Dr. Andrew Marderstein is a Research Fellow at Memorial Sloan Kettering Cancer Center in the Clinical Genetics Service, where his research focuses on uncovering the cellular and molecular mechanisms driven by inherited genetic factors. Previously, he was a Dean's Postdoctoral Fellow at Stanford University with Stephen Montgomery and completed his PhD in the Tri-Institutional Computational Biology & Medicine Program at Weill Cornell Medicine with Olivier Elemento and Andy Clark.

Join us on Friday, 2/21 at 12-1 PM ET for our next seminar: The NCI's Human Tumor Atlas Network (HTAN): Generating Spatial Atlases of Cancer Transitions presented by Sean Hanlon of National Cancer Institute (NCI)! https://lnkd.in/eGWhEDDe The overarching mission of the Human Tumor Atlas Network (HTAN) is to construct dynamic 3D atlases of human cancers. This presentation will describe the goals and progress of the HTAN program. Additionally, the talk will highlight the extensive single cell and spatial omics datasets and other resources generated by HTAN that are available to the broader scientific community. Dr. Sean E. Hanlon is Acting Deputy Director of the NCI Center for Strategic Scientific Initiatives (CSSI) where he provides leadership in the planning, developing, and implementing initiatives with a focus on emerging areas of science with potential impact across the cancer research continuum. Dr. Hanlon is committed to advancing the field of cancer research through open science, technology development, and transdisciplinary collaboration. 

Applications for the 2025 Biomedical Data Science Innovation Lab: Quantitative Approaches in Spatial Multi-Omics for Guiding Personalized Medicine are due at the end of this week on Friday, February 14 at 11:59 PM ET! The BDSIL is designed as an extended, hybrid program featuring online team-building activities and scientific presentations, culminating in a 5-day, in-person intensive workshop on June 16-20, 2025 at the Hutton Hotel in Nashville, Tennessee. Working under the direction of professional facilitators and the guidance of experienced mentors, teams at the event will develop interdisciplinary research projects to generate creative strategies focused on the use of data science approaches in spatial multi-omics, particularly as applied to understanding cancer and rare diseases. In addition, the lab will include opportunities for learning about project funding through interaction with program officers. Apply today on the BDSIL website: https://lnkd.in/eEPpr7uv Knowinnovation UVA School of Data Science Academic Data Science Alliance NIH Office of Data Science Strategy National Institute of General Medical Sciences (NIGMS) #datascience #workshop #academicworkshop #teamscience #genomicsresearch #researchprojects

Applications for the 2025 Biomedical Data Science Innovation Lab: Quantitative Approaches in Spatial Multi-Omics for Guiding Personalized Medicine are due at the end of this week on Friday, February 14 at 11:59 PM ET! The BDSIL is designed as an extended, hybrid program featuring online team-building activities and scientific presentations, culminating in a 5-day, in-person intensive workshop on June 16-20, 2025 at the Hutton Hotel in Nashville, Tennessee. Working under the direction of professional facilitators and the guidance of experienced mentors, teams at the event will develop interdisciplinary research projects to generate creative strategies focused on the use of data science approaches in spatial multi-omics, particularly as applied to understanding cancer and rare diseases. In addition, the lab will include opportunities for learning about project funding through interaction with program officers. Apply today on the BDSIL website: https://lnkd.in/eEPpr7uv Knowinnovation UVA School of Data Science Academic Data Science Alliance NIH Office of Data Science Strategy National Institute of General Medical Sciences (NIGMS) #datascience #workshop #academicworkshop #teamscience #genomicsresearch #researchprojects

Applications for the 2025 Biomedical Data Science Innovation Lab: Quantitative Approaches in Spatial Multi-Omics for Guiding Personalized Medicine are due at the end of this week on Friday, February 14 at 11:59 PM ET! The BDSIL is designed as an extended, hybrid program featuring online team-building activities and scientific presentations, culminating in a 5-day, in-person intensive workshop on June 16-20, 2025 at the Hutton Hotel in Nashville, Tennessee. Working under the direction of professional facilitators and the guidance of experienced mentors, teams at the event will develop interdisciplinary research projects to generate creative strategies focused on the use of data science approaches in spatial multi-omics, particularly as applied to understanding cancer and rare diseases. In addition, the lab will include opportunities for learning about project funding through interaction with program officers. Apply today on the BDSIL website: https://lnkd.in/eEPpr7uv Knowinnovation UVA School of Data Science Academic Data Science Alliance NIH Office of Data Science Strategy National Institute of General Medical Sciences (NIGMS) #datascience #workshop #academicworkshop #teamscience #genomicsresearch #researchprojects

Join us on Friday, 2/14 for our next seminar: Methods for Population-Scale Single Cell and Spatial Multi-omics Data Analysis presented by Dr. Hongzhe Li of Penn Medicine, University of Pennsylvania Health System! https://lnkd.in/dxpYfGRS Population-level single-cell gene expression data captures the gene expressions of thousands of cells from each individual within a sizable cohort. This data enables the construction of cell-type- and individual-specific gene expression distributions and gene co-expression networks. This talk will present new statistical methods for link such individual-level gene expression distributions to covariates or phenotypes in the general framework of object data regression.     Dr. Hongzhe Li is Perelman Professor of Biostatistics, Epidemiology and Informatics at the Perelman School of Medicine at the University of Pennsylvania.  He is Vice Chair for Research Integration, Director of Center of Statistics in Big Data and former Chair of the Graduate Program in Biostatistic at Penn. Dr. Li’s research focuses on developing statistical and computational methods for analysis of large-scale genetic, genomics and metagenomics data and theory on high dimensional statistics. 

Tune in on Friday, 2/7 at 12-1 PM for our next seminar: The Challenges and Opportunities of Incorporating Diverse Populations in Multi-omics Research: https://lnkd.in/dXhYf5Y9 Multi-omics research has brought about new advances in precision medicine. However, it also has the potential to widen existing health disparities. It is critical to consider the role of diverse populations in multi-omics research when designing studies to advance precision health. Dr. Seyerle is an Assistant Professor at the University of North Carolina where her research focuses on the molecular etiology of adverse drug reactions and variable drug response. A critical focus of her work is the inclusion of diverse populations to expand the impact of precision health advances. 

The 2025 Biomedical Data Science Innovation Lab application deadline has been extended to February 14th, 2025! Read below and visit our website to apply and learn more ⬇️ The BDSIL is designed as an extended, hybrid program featuring online team-building activities and scientific presentations, culminating in a 5-day, in-person intensive workshop on June 16-20, 2025 at the Hutton Hotel in Nashville, Tennessee. Working under the direction of professional facilitators and the guidance of experienced mentors, teams at the event will develop interdisciplinary research projects to generate creative strategies focused on the use of data science approaches in spatial multi-omics, particularly as applied to understanding cancer and rare diseases. In addition, the lab will include opportunities for learning about NIH and NSF funding through interaction with program officers. Learn more and apply to the 2025 Biomedical Data Science Innovation Lab at: https://lnkd.in/eEPpr7uv Knowinnovation UVA School of Data Science National Institute of General Medical Sciences (NIGMS) NIH Office of Data Science Strategy #DataScience #Biomed #Biomedicine #BuildingPartnerships #academicworkshop #workshop #educationalprogram #researchworkshop #Genomics #TeamScience #cancerresearch #gemonicsresearch

1 day left to apply to the 2025 BDSIL! Get those applications in by January 31st at 11:59 PM ET! https://lnkd.in/eEPpr7uv

Apply Now -- Applications for the 2025 Biomedical Data Science Innovation Lab (BDSIL) are due in just a few days on January 31 at 11:59 PM ET! You won't want to miss out on this unique collaborative 5-day project-writing workshop this June! The BDSIL is designed as an extended, hybrid program featuring online team-building activities and scientific presentations, culminating in a 5-day, in-person intensive workshop on June 16-20, 2025 at the Hutton Hotel in Nashville, Tennessee. Working under the direction of professional facilitators and the guidance of experienced mentors, teams at the event will develop interdisciplinary research projects to generate creative strategies focused on the use of data science approaches in spatial multi-omics, particularly as applied to understanding cancer and rare diseases. In addition, the lab will include opportunities for learning about NIH and NSF funding through interaction with program officers. Learn more and apply to the 2025 Biomedical Data Science Innovation Lab at: https://lnkd.in/eEPpr7uv Knowinnovation UVA School of Data Science National Institute of General Medical Sciences (NIGMS) NIH Office of Data Science Strategy #DataScience #Biomed #Biomedicine #BuildingPartnerships #academicworkshop #workshop #educationalprogram #researchworkshop #Genomics #TeamScience #cancerresearch #gemonicsresearch