The 7 Best Probiotics for Weight Loss, According to Registered Dietitians
Probiotics seem to be everywhere these days, both as standalone supplements and as additions to collagen and greens powders, with the global probiotic market expected to hit $73 billion in 2025.
These beneficial microorganisms are most famously celebrated for their positive impact on gut health. But research suggests probiotics might also contribute to weight loss, especially for those who are already overweight or obese.
“An imbalanced gut microbiota can impact appetite-regulating hormones and fat storage, leading to a higher body weight,” says Sheri Gaw, RDN, CDCES, the owner of Sheri the Plant Strong Dietitian.
To help you demystify the world of probiotic supplements, our nutrition experts rounded up the seven best probiotics for weight loss for different genders and uses so you can choose the best option for you.
The 7 Best Probiotics for Weight Loss
- Our pick: UltraFlora Control by Metagenics
- Best for women: Garden of Life's Once Daily Women's Probiotic
- Best for men: Biotics 8
- Best for menopausal weight loss: Culturelle’s Women’s Wellness Probiotic
- Best for gut health: RenewLife’s Extra Care Digestive Probiotic
- Best for bloating: Phillips Colon Health 4-in-1 Probiotics
- Best budget: NOW-Probiotic-10
Our Pick
UltraFlora Control by Metagenics
Pros
- Easy to swallow
- Tastes good
- Contains research-backed strains
- Third-party tested
Cons
- May cause gas in some
- Pricey
How to take it: Take 1 capsule daily with food. No refrigeration required.
UltraFlora Control by Metagenics contains Bifidobacterium lactis B420, a probiotic strain that “has been shown in a top-quality study to help with weight loss, and Health Canada even approves it for that purpose,” says Elena Usdenski, RD, a certified fertility and prenatal dietitian.
“In [another older] study, people who took this probiotic without changing anything else about their habits lost about 5 percent of their body fat over six months,” adds Usdenski.
While further studies are needed, this supplement contains a probiotic strain with the potential to aid in weight loss.
This supplement provides a potent dose of 10 billion CFU, or colony-forming units, which meets the recommended minimum requirement of at least 1 billion CFU by the National Institutes of Health. The CFU count specifies the number of live bacteria in the supplement.
Best for Women
Garden of Life Once Daily Women’s Probiotic
Pros
- Third-party tested
- Doctor-formulated
- Affordable
- Contains research-backed strains
Cons
- Contains prebiotics, which may cause stomach discomfort
Garden of Life is our pick for the best probiotic for weight loss for women, as the strains present are beneficial for women’s vaginal health and weight management. The Garden of Life brand is doctor-formulated.
“Garden of Life Once Daily Women's Probiotic is third-party verified and contains 16 probiotic strains, including L. reuteri and L. fermentum — clinically studied strains shown to support women’s health. It’s guaranteed [to contain] 50 billion CFUs. It also contains prebiotic fiber,” says Katherine Brooking, a registered dietitian in New York City.
Prebiotics are beneficial fibers that feed probiotic bacteria, fostering their growth and activity in the body. But while prebiotics are generally beneficial, some people may experience gas or bloating as they adjust to taking them.
Several other strains present in this product have also been linked to weight loss, specifically including Lactobacillus gasseri, L. rhamnosus, and Bifidobacterium lactis.
Best for Men
Biotics 8
Pros
- GMP-certified
- Contains vitamin D
- Includes digestive enzymes
- 60-day money-back guarantee
Cons
- 1 dose is 3 capsules
- Pricey
- Contains prebiotics, which may cause stomach discomfort
Biotics 8 is our top choice for men, as the 10 probiotic strains present may be beneficial for men’s gut health. We love that this supplement is GMP-certified for good manufacturing practices, ensuring its production is held to the highest safety and quality standards.
“Biotics 8 provides both Lactobacillus and Bifidobacterium, the specific strains shown to support weight management. With a substantial dosage of 20 billion CFUs per serving, Biotics 8 ensures that men receive a sufficient amount of beneficial bacteria to optimize not only their gut health but also their weight management efforts,” says Emily Hirsch, RD, a health writer and the owner of South Charlotte Nutrition in North Carolina.
“The product also provides 10 micrograms (mcg) of vitamin D3, which is a nice added bonus as some studies have found a connection between optimal vitamin D levels and healthy testosterone levels. Additionally, the product contains a variety of digestive enzymes to help prevent digestive discomfort,” adds Hirsch.
Moreover, it contains chicory root prebiotic fiber, which can help feed the multiple probiotic strains present.
Best for Menopausal Weight Loss
Culturelle Women’s Wellness Probiotic
Pros
- Research-backed strains
- Chewable form
- Special lining to preserve freshness
- Third-party tested
Cons
- Some dislike the taste
- May cause bloating
Culturelle Women’s Wellness Probiotic is our top pick for menopausal weight loss, based on its variety of strains that support women’s health. According to U.S. News & World Report, Culturelle is the No. 1 recommended pharmacist brand and is well respected within the healthcare community for its high-quality ingredients, manufacturing process, and stringent product testing.
This product contains 12 billion CFUs and five Lactobacillus strains linked to weight loss and women’s health.
“Culturelle’s Women’s Wellness Probiotic has several probiotic strains that support women’s health in general, but they include the strain Lactobacillus rhamnosus, which [some] research shows may aid in weight loss, and may be more effective in women than men,” says Jen Scheinman, RDN, the owner of Next Jen Health. The four other strains present are abundantly found in healthy vaginal microbiomes.
These Culturelle chewables are also packaged with a special desiccant (a drying agent that can be made of materials like silica gel or calcium oxide) lining to absorb moisture and protect the viability of the live bacteria present. And if you prefer a chewable over a pill, this mixed berry chew is tasty.
Best for Gut Health
RenewLife’s Extra Care Digestive Probiotic
Pros
- Research-backed strains
- Potent 50 billion CFU dose
- Vegetarian-friendly
- Affordable
Cons
- Off-putting smell
- May cause diarrhea
If you’re looking for general gut health support in addition to weight loss, RenewLife’s Extra Care Digestive Probiotic is a good choice. And by improving your gut health, you may also be able to support your weight loss efforts by default.
“This particular probiotic features 50 billion CFUs and contains 12 different diverse probiotic strains in just one capsule per day. By including a variety of strains, the probiotic helps to target a range of digestive issues, including bloating, constipation, and occasional gas,” says Kathryn Durston, RDN, the owner of Naturally Good Nutrition.
“It also includes one of the most well-researched probiotic strains for gut health, the Lactobacillus rhamnosus GG strain, which was the first probiotic strain to be patented back in 1989 for its gut health benefits,” adds Durston.
Bifidobacterium lactis is also one of the most prominent strains in this supplement, one of the top strains linked to weight loss.
According to Durston, “You can take RenewLife’s probiotic as a preventive measure to support daily digestive health.”
While not common, a few people reported diarrhea after taking this supplement, and the product had a strong flowery and alcohol-like smell.
Best for Bloating
Phillips Colon Health 4-in-1 Probiotics
Pros
- Research-backed strains
- Product transparency
- Affordable
Cons
- Not available direct from manufacturer
- Lower CFU count
If you suffer from occasional bloating, Phillips Colon Health 4-in-1 Daily Probiotic contains a formulation that can reduce abdominal bloating.
“To minimize bloating, I recommend Phillips Colon Health 4-in-1 probiotics. These capsules contain Bifidobacterium bifidum, a strain of bacteria that research shows can help reduce abdominal bloating,” says Sarah Garone, a nutritionist and food writer.
This product contains 3 billion CFU two targeted strains: Lactobacillus rhamnosus and Bifidobacterium animalis subsp. lactis (BB-12), one of the most studied probiotic strains of the Bifidobacterium genus.
In addition to occasional bloating, L. rhamnosus may reduce bloating related to irritable bowel syndrome (IBS), some research suggests.
Best Budget
NOW Probiotic-10
Pros
- Research-backed strains
- Third-party tested
- Easy-to-swallow capsule
- Affordable
Cons
- May cause cramps or constipation
- Product can be delivered too warm
If you’re looking for a budget-friendly option, NOW Probiotic-10 is a good, affordable choice. The NOW supplement brand is well known and respected in the registered dietitian community because of its stringent testing and quality standards.
“NOW’s Probiotic-10 formula provides a blend of 10 different probiotic strains, including Lactobacillus and Bifidobacterium, which are known for their beneficial effects on gut health and weight management. This product provides 25 billion CFUs per serving at a very reasonable price point,” says Hirsch.
This product is also unique in that the probiotic strains have been identity-verified using DNA-fingerprinting technology, ensuring accuracy on labeling.
“I recommend NOW Probiotic-10 for its variety of live probiotic strains that are known to naturally thrive in the digestive tract,” echoes Gaw.
One factor some customers noted was that the product can come delivered too warm, which could affect the viability of the bacteria present. To reduce this risk, it’s best to try to be home when the product is delivered so you can quickly transfer the bottle to a cool, dry place.
Why You Can Trust Us
We consulted with nine qualified nutrition experts, including registered dietitians, when selecting the best probiotics for weight loss in each respective category. You can trust our reviews as we participate in the following practices:
- Engage in ongoing independent research, which includes examining peer-reviewed studies for data that supports the ingredients we recommend
- Consult with credentialed subject matter experts for their knowledge, opinions, and guidance on our recommended products. These experts do not have any financial conflicts of interest.
- Use and test some of the products ourselves to provide real-world experience
We independently chose the best probiotic supplements based on brand trustworthiness, third-party testing, the presence of research-backed strains for weight loss, and more. We also hand-picked products with positive customer reviews and that were transparent in their research.
Things to Know About Probiotics
If you’re interested in using probiotics for weight loss, the first thing you should do is consult your healthcare provider. Before starting one, there are a few important factors to know about probiotics.
They won’t work right away. “If you try probiotics as part of a weight loss plan, don’t expect to see results for a while. The research shows it can take up to six months, and you may only lose a few pounds,” says Kim Kulp, RDN, a registered dietitian-nutritionist and gut-health expert. At minimum, most research shows at least 12 weeks of consistent probiotic use is needed before a weight loss effect is seen.
Take them at any time of day. “Keep them in a place where you’ll be reminded to take them, such as next to your toothbrush or coffee pot,” says Kulp. Make sure to read the instructions on the bottle to determine whether to take with or without food, and when to take them.
They may upset your tummy at first. Introducing new microbes to your gut microbiome can cause gas, bloating, or other discomforts at first. To lessen the discomfort, take the probiotic with your meals. Start slow. If the instructions state to take two pills, start with one pill. Then slowly increase the dose. Oftentimes, the discomfort eases after a few days.
They’re safe — for most people. Kulp tells us: “Most research shows probiotics to be safe, but since they are living microbes, those who are immunocompromised shouldn’t take them without consulting their doctor.”
Probiotics alone probably won’t help you lose weight. The foundation for a healthy weight remains a combination of physical exercise, stress reduction, and a healthy diet. Adding probiotics may help, but won’t do the trick by itself.
“The data on using probiotics for weight loss are still in its early stages, but in general probiotics are safe for most healthy people,” says Scheinman.
What to Look for in a Probiotic for Weight Loss
To find the best probiotic supplement for your weight loss journey, consider these important factors.
Intended Use Pay special attention to the product's claims and specific strains to see if they align with your health needs. “Multiple strains are better than single-strain probiotics. Ask your dietitian which strain might be beneficial to your condition” says Lisa Andrews, RD, the owner of Sound Bites Nutrition.
“And when choosing a probiotic supplement for weight loss, look for supplements that contain strains that have been shown to be effective for weight loss, such as Lactobacillus and Bifidobacterium,” adds Hirsch.
Dose Look for supplements that contain at least 1 billion CFUs, the minimum amount seen to produce a benefit in most studies.
Ingredients Review the ingredient list carefully and steer clear of supplements with artificial fillers, preservatives, and other additives.
Third-Party Testing When choosing a supplement, it’s important to look for verification of third-party testing, such as United States Pharmacopeia (USP) and National Sanitation Foundation (NSF) certifications, to ensure the products meet safety and quality standards.
Research Transparency “The first thing I like to look at is if the company can provide you with any studies to back up the claims they are making. And double-check that those studies are done in humans,” says Scheinman.
FAQs
Lactobacillus and Bifidobacterium strains, specifically L. rhamonus, L. gasseri, and B. lactis are the most well-researched strains regarding weight loss.
In one randomized controlled trial, B. lactis and L. gasseri strains were associated with reduced waist circumference and abdominal fat loss after at least 12 weeks of use.
Bifidobacterium bifidum is one of the most prominent strains in the research to reduce abdominal bloating, especially in those with irritable bowel disease. L. gasseri and B. lactis are also linked to reduced belly fat.
While certain probiotics appear to support weight loss, there is no proof they speed up weight loss. Per the research so far, it’s likely that a combination of a healthy diet and lifestyle coupled with probiotics may produce the best weight loss results.
Everyday Health follows strict sourcing guidelines to ensure the accuracy of its content, outlined in our editorial policy. We use only trustworthy sources, including peer-reviewed studies, board-certified medical experts, patients with lived experience, and information from top institutions.
Resources
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