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Machine learning to build predictive models in maternal-fetal medicine

Guest Editors

Tess Cersonsky, MD, Icahn School of Medicine at Mount Sinai, USA
Alyssa Hochberg, MD, MPH, McGill University, Canada


BMC Pregnancy and Childbirth called for submissions to our Collection on Machine learning to build predictive models in maternal-fetal medicine. 

This Collection aimed to advance maternal-fetal medicine by leveraging innovations in machine learning technologies. Maternal-fetal medicine seeks to safeguard the health of both mother and unborn child during pregnancy and childbirth, yet despite medical advancements, complications persist, leading to adverse outcomes like maternal mortality and neonatal morbidity. The integration of machine learning offers a promising avenue to harness clinical data for predictive modeling, empowering healthcare professionals to detect subtle risk factors that conventional diagnostics may overlook.

New Content ItemThis Collection supports and amplifies research related to SDG 3: Good Health and Well-Being.

Meet the Guest Editors

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Tess Cersonsky, MD, Icahn School of Medicine at Mount Sinai, USA

Dr Cersonsky is a resident at Mount Sinai Hospital (Icahn School of Medicine, NY) in the Department of Obstetrics, Gynecology, and Reproductive Sciences. Her research interests include the use of machine learning for predicting adverse pregnancy outcomes, placental disorders, and psychological sequelae of adverse pregnancy events. Her background in biomedical engineering and biomedical informatics has led her to apply machine learning and computational modeling to obstetric phenomena.

Alyssa Hochberg, MD, MPH, McGill University, Canada

Alyssa Hochberg, MD, MPH, completed her Obstetrics & Gynecology residency in 2021 with distinction at Rabin Medical Center and Tel Aviv University, Israel. She is currently completing her postgraduate training in Reproductive Endocrinology and Infertility at McGill University, Canada. Her special research interests are obstetrical outcomes following IVF, and laboratory, obstetric, and perinatal outcomes of poor and high responders.    

About the Collection

BMC Pregnancy and Childbirth called for submissions to our Collection on Machine learning to build predictive models in maternal-fetal medicine. 

Maternal-fetal medicine encompasses a broad spectrum of healthcare aimed at ensuring the well-being of both the mother and the unborn child during pregnancy and childbirth. Despite significant advancements in medical technology and obstetric care, maternal and fetal complications continue to pose substantial challenges, contributing to adverse outcomes such as maternal mortality, stillbirths, and neonatal morbidity. With the advent of machine learning technologies, there is a significant opportunity to leverage vast amounts of clinical data to develop predictive models that can aid healthcare professionals to identify subtle patterns and predictors of adverse outcomes that may elude conventional diagnostic approaches.

BMC Pregnancy and Childbirth launched a Collection, Machine learning to build predictive models in maternal-fetal medicine, to facilitate the understanding of how machine learning algorithms can enhance clinical decision-making, improve patient outcomes, and ultimately reduce maternal and fetal morbidity and mortality rates. The Collection invited researchers and clinicians in fields including maternal-fetal medicine, high-risk obstetrics, midwifery, gynecology, perinatology, computer science, and statistics to contribute research that explores topics including, but not limited to, the prediction of gestational complications, fetal anomaly detection, preterm birth forecasting, preeclampsia risk assessment, anticipation of maternal hemorrhage, neonatal outcome prediction, integration of multi-modal data, and the development of clinical decision support systems using machine learning techniques in maternal-fetal medicine.

This Collection supports and amplifies research related to SDG 3: Good Health and Well-Being.

Image credit: © ryanking999 / stock.adobe.com

  1. This study aimed to develop and evaluate a nomogram for predicting preterm birth in patients with intrahepatic cholestasis of pregnancy (ICP), with a view to assisting clinical management and intervention.

    Authors: Wenchi Xie, Landie Ji, Dan Luo, Lili Ye, Qian Li, Landan Kang, Qingquan He and Jie Mei
    Citation: BMC Pregnancy and Childbirth 2025 25:194
  2. With the implementation of China’s three-child policy, an increasing number of Chinese women are not opting for cesarian delivery (CD), with particular concern about intrapartum CD. At the same time, reducing ...

    Authors: Xinrui Zhao, Lijun Yang, Jing Peng, Kai Zhao, Weina Xia and Yun Zhao
    Citation: BMC Pregnancy and Childbirth 2025 25:164
  3. Fetal growth restriction (FGR) is a leading risk factor for stillbirth, yet the diagnosis of FGR confers considerable prognostic uncertainty, as most infants with FGR do not experience any morbidity. Our objec...

    Authors: Raquel M. Zimmerman, Edgar J. Hernandez, Mark Yandell, Martin Tristani-Firouzi, Robert M. Silver, William Grobman, David Haas, George Saade, Jonathan Steller and Nathan R. Blue
    Citation: BMC Pregnancy and Childbirth 2025 25:80
  4. Breastfeeding is the optimal source of nutrition for infants and young children, essential for their healthy growth and development. However, a gap in cohort studies tracking breastfeeding up to six months pos...

    Authors: Yi Liu, Jie Xiang, Ping Yan, Yuanqiong Liu, Peng Chen, Yujia Song and Jianhua Ren
    Citation: BMC Pregnancy and Childbirth 2024 24:858
  5. Maternal morbidity and mortality remain critical health concerns globally. As a result, reducing the maternal mortality ratio (MMR) is part of goal 3 in the global sustainable development goals (SDGs), and pre...

    Authors: Sulaiman Salim Al Mashrafi, Laleh Tafakori and Mali Abdollahian
    Citation: BMC Pregnancy and Childbirth 2024 24:820
  6. Preterm birth (PTB) is a significant cause of neonatal mortality and long-term health issues. Accurate prediction and timely prevention of PTB are essential for reducing associated child mortality and morbidit...

    Authors: Liwen Ding, Xiaona Yin, Guomin Wen, Dengli Sun, Danxia Xian, Yafen Zhao, Maolin Zhang, Weikang Yang and Weiqing Chen
    Citation: BMC Pregnancy and Childbirth 2024 24:810
  7. Changes in body temperature anticipate labor onset in numerous mammals, yet this concept has not been explored in humans. We investigated if continuous body temperature exhibits similar changes in women and wh...

    Authors: Chinmai Basavaraj, Azure D. Grant, Shravan G. Aras and Elise N. Erickson
    Citation: BMC Pregnancy and Childbirth 2024 24:777
  8. Observational epidemiological studies suggested that immunological dysregulation and inflammation play a significant role in the placental and renal dysfunction that leads to maternal hypertension. The immunop...

    Authors: Jingting Liu, Yijun Dong, Yawei Zhou, Wendi Wang, Yan Li and Jianying Pei
    Citation: BMC Pregnancy and Childbirth 2024 24:756
  9. Gestational weight gain (GWG) is a critical factor influencing maternal and fetal health. Excessive or insufficient GWG can lead to various complications, including gestational diabetes, hypertension, cesarean...

    Authors: Audêncio Victor, Hellen Geremias dos Santos, Gabriel Ferreira Santos Silva, Fabiano Barcellos Filho, Alexandre de Fátima Cobre, Liania A. Luzia, Patrícia H.C. Rondó and Alexandre Dias Porto Chiavegatto Filho
    Citation: BMC Pregnancy and Childbirth 2024 24:733
  10. Newborns are shaped by prenatal maternal experiences. These include a pregnant person’s physical health, prior pregnancy experiences, emotion regulation, and socially determined health markers. We used a serie...

    Authors: Robert D. Henry
    Citation: BMC Pregnancy and Childbirth 2024 24:603
  11. We aimed to determine the best-performing machine learning (ML)-based algorithm for predicting gestational diabetes mellitus (GDM) with sociodemographic and obstetrics features in the pre-conceptional period.

    Authors: Yeliz Kaya, Zafer Bütün, Özer Çelik, Ece Akça Salik, Tuğba Tahta and Arzu Altun Yavuz
    Citation: BMC Pregnancy and Childbirth 2024 24:574

Submission Guidelines

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This Collection welcomes submission of original Research Articles. Should you wish to submit a different article type, please read the submission guidelines to confirm that type is accepted by the journal you are submitting to. Articles for this Collection should be submitted via our submission system, Snapp. During the submission process you will be asked whether you are submitting to a Collection, please select "Machine learning to build predictive models in maternal-fetal medicine" from the dropdown menu.

Articles will undergo the standard peer-review process of the journal and are subject to all of the journal’s standard policies. Articles will be added to the Collection as they are published.

The Editors have no competing interests with the submissions which they handle through the peer review process. The peer review of any submissions for which the Editors have competing interests is handled by another Editorial Board Member who has no competing interests.