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The Yuggs (or Yuggya) are fictional creatures in the Cthulhu Mythos of H. P. Lovecraft. The beings were created by Lin Carter and first appeared in his short story "Out of the Ages".
In particular it be those of the minions that inhabit the noisome depths beneath the Earth's crust that lure men to their dreadful service through promise of wealth; for all the ore and riches of the world be theirs to dispense, aye, mines of gold and great heaps of inestimable gems. Of these, the Yuggs, whose name the Scribe rendereth as the Worms of the Earth, are by far the most to be feared, for it is said there be many a rich and wealthy man bestriding the proud ways of the world today, the secret of whose wealth lies in acursed treasure brought to his feet by the immense and loathsome, the white and slimy Yuggs, whereby to purchase his service to their Cause, to the utter and most damnable betrayal of humankind, and the imperilment of the very Earth.
—excerpt from John Dee's translation of the Necronomicon
Ubiquitin is a protein that in humans is encoded by the UBB gene.
Ubiquitin is one of the most conserved proteins known in eukaryotic organisms. Ubiquitin is required for ATP-dependent, non-lysosomal intracellular protein degradation of abnormal proteins and normal proteins with a rapid turnover. Ubiquitin is covalently bound to proteins to be degraded, and presumably labels these proteins for degradation. Ubiquitin also binds to histone H2A in actively transcribed regions but does not cause histone H2A degradation, suggesting that ubiquitin is also involved in regulation of gene expression. This gene consists of three direct repeats of the ubiquitin coding sequence with no spacer sequence. Consequently, the protein is expressed as a polyubiquitin precursor with a final amino acid after the last repeat. Aberrant form of this protein (UBB+1) has been noticed in patients with Alzheimer's disease, Down syndrome, other tauopathies (e.g. Pick's disease) and polyglutamine disease (e.g. Huntington's disease).