The epidermis is composed of the outermost layers of cells in the skin, "epi" in Greek meaning "over" or "upon", which together with the dermis forms the cutis.
The epidermis is a stratified squamous epithelium, composed of proliferating basal and differentiated suprabasal keratinocytes which acts as the body's major barrier against an inhospitable environment, by preventing pathogens from entering, making the skin a natural barrier to infection. It also regulates the amount of water released from the body into the atmosphere through transepidermal water loss (TEWL).
In humans, it is thinnest on the eyelids at 0.05 mm (0.0020 in) and thickest on the palms and soles at 1.5 mm (0.059 in). It is ectodermal in origin.
The epidermis is avascular, nourished almost exclusively by diffused oxygen from the surrounding air. It is 95% keratinocytes but also containing melanocytes, Langerhans cells, Merkel cells, and inflammatory cells. Rete ridges ("rete tips") are epidermal thickenings that extend downward between dermal papillae.Blood capillaries are found beneath the epidermis, and are linked to an arteriole and a venule.
In zoology, the epidermis is an epithelium (sheet of cells) that covers the body of an eumetazoan (animal more complex than a sponge). Eumetazoa have a cavity lined with a similar epithelium, the gastrodermis, which forms a boundary with the epidermis at the mouth.
Sponges have no epithelium, and therefore no epidermis or gastrodermis. The epidermis of a more complex invertebrate is just one layer deep, and may be protected by a non-cellular cuticle. The epidermis of a higher vertebrate has many layers, and the outer layers are reinforced with keratin and then die.
The epidermis cells (from the Greek "επίδερμίδα", meaning "over-skin") is a single-layer of cells that covers the leaves, flowers, roots and stems of plants. It forms a boundary between the plant and the external environment. The epidermis serves several functions, it protects against water loss, regulates gas exchange, secretes metabolic compounds, and (especially in roots) absorbs water and mineral nutrients. The epidermis of most leaves shows dorsoventral anatomy: the upper (adaxial) and lower (abaxial) surfaces have somewhat different construction and may serve different functions. Woody stems and some other stem structures produce a secondary covering called the periderm that replaces the epidermis as the protective covering.
The epidermis is the outermost cell layer of the primary plant body. In some older works the cells of the leaf epidermis have been regarded as specialised parenchyma cells, but the established modern preference has long been to classify the epidermis as dermal tissue, whereas parenchyma is classified as ground tissue. The epidermis is main component of the dermal tissue system of leaves (diagrammed below), and also stems, roots, flowers, fruits, and seeds; it is usually transparent (epidermal cells have a lower number of chloroplasts or lack them completely, except for the guard cells.)