Nathaniel Wand

Nathaniel Wand

London, England, United Kingdom
252 followers 250 connections

About

I am a qualified UK and European patent attorney, having passed the final UK and European…

Activity

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Experience

  • D Young & Co LLP Graphic
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    London, England, United Kingdom

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    London, United Kingdom

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    Swindon, United Kingdom

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    Cambridge, United Kingdom

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    Swindon, United Kingdom

Education

  • University of Cambridge Graphic

    University of Cambridge

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    Activities and Societies: University Brass Band, Communications Officer for JCR

    I undertook a natural sciences degree at Girton College, achieving prizes and scholarships each year for first class degree results. For my final year I undertook a project entitled: "An Investigation of Glycine Residues within the G52 Domain from the Staphylococcus aureus Surface Protein G". I was also a committed member of the university brass band and was a member of the JCR committee.

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    Activities and Societies: Birmingham University Brass Band and City of Birmingham Brass Band.

    In my first year I undertook a series of taught courses in biological, physical and computer sciences. I also completed three mini projects:

    1. Raman imaging of model bacterial biofilms (with Tim Overton in Biochemical Engineering)
    2. Cluster analysis of platelet receptors within super-resolution images (with Iain Styles in Computer Sciences)
    3. Nuclear uptake of functionalized luminescent nanoparticles (with Zoe Pikramenou in Chemistry)

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    Activities and Societies: City of Birmingham Brass Band

    On completion of the MSc year, I carried out a PhD research project in the Department of Chemistry entitled: "Single molecule techniques for studying protein-DNA interactions". The aim of this project was to barcode DNA for rapid identification of complex environmental samples.

    I completed my PhD thesis following three years of study under the guidance of Dr. Rob Neely, and was awarded the 2018 Dr SW Challinor Prize for the best PhD thesis.

    My research was published as Wand, N.O…

    On completion of the MSc year, I carried out a PhD research project in the Department of Chemistry entitled: "Single molecule techniques for studying protein-DNA interactions". The aim of this project was to barcode DNA for rapid identification of complex environmental samples.

    I completed my PhD thesis following three years of study under the guidance of Dr. Rob Neely, and was awarded the 2018 Dr SW Challinor Prize for the best PhD thesis.

    My research was published as Wand, N.O. et al. (2019) DNA barcodes for rapid, whole genome, single-molecule analyses. Nucleic Acids Research gkz212.

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Licenses & Certifications

Publications

  • DNA barcodes for rapid, whole genome, single-molecule analyses

    Nucleic Acids Research

    We report an approach for visualizing DNA sequence and using these ‘DNA barcodes’ to search complex mixtures of genomic material for DNA molecules of interest. We demonstrate three applications of this methodology; identifying specific molecules of interest from a dataset containing gigabasepairs of genome; identification of a bacterium from such a dataset and, finally, by locating infecting virus molecules in a background of human genomic material. As a result of the dense fluorescent…

    We report an approach for visualizing DNA sequence and using these ‘DNA barcodes’ to search complex mixtures of genomic material for DNA molecules of interest. We demonstrate three applications of this methodology; identifying specific molecules of interest from a dataset containing gigabasepairs of genome; identification of a bacterium from such a dataset and, finally, by locating infecting virus molecules in a background of human genomic material. As a result of the dense fluorescent labelling of the DNA, individual barcodes of the order 40 kb pairs in length can be reliably identified. This means DNA can be prepared for imaging using standard handling and purification techniques. The recorded dataset provides stable physical and electronic records of the total genomic content of a sample that can be readily searched for a molecule or region of interest.

    See publication

Organizations

  • European Patent Institute (epi)

    Member

    - Present
  • Chartered Institute of Patent Attorneys (CIPA)

    Fellow

    - Present

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