Piracetam

(IUPAC) ime
	2-okso-1-pirolidineacetamid
Klinički podaci
Robne marke	Breinox, Dinagen, Lucetam, Nootropil, Nootropyl, Oikamid, i mnoga druga
AHFS/Drugs.com	Internacionalno ime leka
Identifikatori
CAS broj	7491-74-9
ATC kod	N06BX03
PubChem	4843
ChemSpider	4677
UNII	ZH516LNZ10
KEGG	D01914
ChEMBL	CHEMBL36715
Hemijski podaci
Formula	C6H10N2O2
Mol. masa	142,156
SMILES	eMolekuli & PubHem
InChI
	InChI=1S/C6H10N2O2/c7-5(9)4-8-3-1-2-6(8)10/h1-4H2,(H2,7,9) ; Key: GMZVRMREEHBGGF-UHFFFAOYSA-N
Farmakokinetički podaci
Bioraspoloživost	~100%
Poluvreme eliminacije	4 - 5 sata
Izlučivanje	Urinarno
Farmakoinformacioni podaci
Trudnoća	?
Pravni status	POM (UK)
Način primene	Oralno i parenteralno

Piracetam je nootropni lek. Njegovo hemijsko ime je 2-okso-1-pirolidin acetamid. On ima zajedničku 2-okso-pirolidonsku strukturu sa 2-okso-pirolidin karboksilnom kiselinom (piroglutamatom). Piracetam je ciklični GABA derivat. On pripada grupi racetama. Piracetam se koristi za mioklonus.^[6]^[7]

Popularna trgovačka imena piracetama u Evropi su Nootropil i Lucetam, između ostalih.

Reference

↑ Li Q, Cheng T, Wang Y, Bryant SH (2010). „PubChem as a public resource for drug discovery.”. Drug Discov Today 15 (23-24): 1052-7. DOI:10.1016/j.drudis.2010.10.003. PMID 20970519. edit
↑ Evan E. Bolton, Yanli Wang, Paul A. Thiessen, Stephen H. Bryant (2008). „Chapter 12 PubChem: Integrated Platform of Small Molecules and Biological Activities”. Annual Reports in Computational Chemistry 4: 217-241. DOI:10.1016/S1574-1400(08)00012-1.
↑ Hettne KM, Williams AJ, van Mulligen EM, Kleinjans J, Tkachenko V, Kors JA. (2010). „Automatic vs. manual curation of a multi-source chemical dictionary: the impact on text mining”. J Cheminform 2 (1): 3. DOI:10.1186/1758-2946-2-3. PMID 20331846. edit
↑ Joanne Wixon, Douglas Kell (2000). „Website Review: The Kyoto Encyclopedia of Genes and Genomes — KEGG”. Yeast 17 (1): 48–55. DOI:10.1002/(SICI)1097-0061(200004)17:1<48::AID-YEA2>3.0.CO;2-H.
↑ Gaulton A, Bellis LJ, Bento AP, Chambers J, Davies M, Hersey A, Light Y, McGlinchey S, Michalovich D, Al-Lazikani B, Overington JP. (2012). „ChEMBL: a large-scale bioactivity database for drug discovery”. Nucleic Acids Res 40 (Database issue): D1100-7. DOI:10.1093/nar/gkr777. PMID 21948594. edit
↑ „Nootropil”. NetDoctor.co.uk. 8. 7. 2004.. Arhivirano iz originala na datum 2012-01-02. Pristupljeno 21. 9. 2009.
↑ UCB Pharma Limited (2005). „Nootropil 800 mg & 1200 mg Tablets and Solution”. electronic Medicines Compendium. Datapharm Communications. Arhivirano iz originala na datum 2006-12-07. Pristupljeno 8. 12. 2005.

Spoljašnje veze

	Portal Medicina
	Portal Hemija

[1] Li Q, Cheng T, Wang Y, Bryant SH (2010). „PubChem as a public resource for drug discovery.”. Drug Discov Today 15 (23-24): 1052-7. DOI:10.1016/j.drudis.2010.10.003. PMID 20970519. edit

[2] Evan E. Bolton, Yanli Wang, Paul A. Thiessen, Stephen H. Bryant (2008). „Chapter 12 PubChem: Integrated Platform of Small Molecules and Biological Activities”. Annual Reports in Computational Chemistry 4: 217-241. DOI:10.1016/S1574-1400(08)00012-1.

[3] Hettne KM, Williams AJ, van Mulligen EM, Kleinjans J, Tkachenko V, Kors JA. (2010). „Automatic vs. manual curation of a multi-source chemical dictionary: the impact on text mining”. J Cheminform 2 (1): 3. DOI:10.1186/1758-2946-2-3. PMID 20331846. edit

[4] Joanne Wixon, Douglas Kell (2000). „Website Review: The Kyoto Encyclopedia of Genes and Genomes — KEGG”. Yeast 17 (1): 48–55. DOI:10.1002/(SICI)1097-0061(200004)17:1<48::AID-YEA2>3.0.CO;2-H.

[5] Gaulton A, Bellis LJ, Bento AP, Chambers J, Davies M, Hersey A, Light Y, McGlinchey S, Michalovich D, Al-Lazikani B, Overington JP. (2012). „ChEMBL: a large-scale bioactivity database for drug discovery”. Nucleic Acids Res 40 (Database issue): D1100-7. DOI:10.1093/nar/gkr777. PMID 21948594. edit

[6] „Nootropil”. NetDoctor.co.uk. 8. 7. 2004.. Arhivirano iz originala na datum 2012-01-02. Pristupljeno 21. 9. 2009.

[7] UCB Pharma Limited (2005). „Nootropil 800 mg & 1200 mg Tablets and Solution”. electronic Medicines Compendium. Datapharm Communications. Arhivirano iz originala na datum 2006-12-07. Pristupljeno 8. 12. 2005.

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