Zebrafish have become a popular organism for the study of vertebrate gene function,. The
virtually transparent embryos of this species, and the ability to accelerate genetic studies by …

To improve understanding of the factors influencing tuberculosis transmission and the role of
pathogen variation, we sequenced all available specimens from patients diagnosed over 15 …

We report genome sequences of 17 inbred strains of laboratory mice and identify almost ten
times more variants than previously known. We use these genomes to explore the …

Background. Recurrent tuberculosis is a major health burden and may be due to relapse
with the original strain or reinfection with a new strain. Methods. In a population-based study …

Abstract The BioMart Community Portal (www. biomart. org) is a community-driven effort to
provide a unified interface to biomedical databases that are distributed worldwide. The …

Checkpoint inhibitors (CPIs) augment adaptive immunity. Systematic pan-tumor analyses
may reveal the relative importance of tumor-cell-intrinsic and microenvironmental features …

Strain-specific genomic diversity in the Mycobacterium tuberculosis complex (MTBC) is an
important factor in pathogenesis that may affect virulence, transmissibility, host response …

Mycobacterium tuberculosis drug resistance (DR) challenges effective tuberculosis disease
control. Current molecular tests examine limited numbers of mutations, and although whole …

Since its first identification in Scotland, over 1,000 cases of unexplained paediatric hepatitis
in children have been reported worldwide, including 278 cases in the UK. Here we report an …

Follicular lymphoma is an incurable B cell malignancy characterized by the t (14; 18)
translocation and mutations affecting the epigenome,. Although frequent gene mutations in …