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49

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(Dr. Merkely Bela)
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ISBN 978-5-209-03987-7
, 2011
, , 2011



The Scientific Society of Medical Students
Peoples Friendship University of Russia


The Faculty of Medicine,
Peoples Friendship University of Russia

.
,
Semmelweis University
Budapest, Hungary

III


6 8 2011, ,
III International Scientific Conference of students and young researchers
Clinical and Theoretical Features of Modern Medicine
6th - 8th April 2011, PFUR, Moscow

Summary
:
Forwards:
. .

Frolov V. A.
Farkashdi Shandor

Merkely Bela
Orgcomitee

. .
Richter Gedeon
Matytsin N. O.
. .
Severin A. E.
-
Medbio sciences

IT in Medicine and Health Care

Therapy

Dentistry

Surgery and traumatology

Psychiatry

Obstetrics and gynecology

Pharmacy
,

Social health and hygiene

Index

4 -10

14
62
69
94
118
156
163
171
190

204

 ()

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On behalf of the Moscow representative of Gedeon Richter (Hungary), we again welcome

the participants of the International Student Scientific Conference "Clinical and theoretical
aspects of modern medicine", which is held in Moscow for the third time. Such scientific
events make an invaluable contribution to the education of future doctors. High
educational level of the conference is provided by participation of leading scientists and
representatives of the pharmaceutical business sharing their theoretical and practical
experience with medical students.
We appreciate the importance of this event and hope to maintain in the future partnership
with the Student Scientific Society of the People's Friendship University.
Dr. Varady Attila
Deputy Director, Moscow Branch, Gedeon Richter

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Dear Friends,
Welcome to the III International Students Scientific Conference Clinical and Theoretical
Features of Modern Medicine in Moscow!
This international platform for scientific exchange is now taking place for the third time
and has been growing constantly. Our aim is make this annual event become the biggest
platform of scientific competitions for students and junior scientist from all over the world.
We cordially invite you to get to know each other, learn from each other, discuss, exchange
ideas and look beyond - this is what our conference represents. We hope that you will
enjoy the keynote lectures, workshops and not to forget- Moscow, during your stay. Your
participation, diligence and activeness in this conference has made the Annual
International Conference Clinical and Theoretical Features of Modern Medicine what it is
today. We hope you will seize this opportunity and benefit from the diversity,
internationality, and enthusiasm. We wish you a fruitful time in Moscow and are happy to
welcome you to the III International Scientific Conference!
The Organizing Committee.

 . , , , 2011 | 11

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 . , , , 2011 | 15
INVESTIGATION OF THE PODOCYTE-SPECIFIC KNOCKOUT OF RAPTOR
AND RICTOR GENES IN MICE
Andrea Debreczeni-Mr
Semmelweis University, Faculty of Medicine VI.
Scientific supervisior: Prof. Dr. Tobias B. Huber
Medicine IV, Nephrology, University Medical Center, Freiburg, Germany
Introduction: The mammalian target of rapamycin (mTOR) signaling
pathway is a central regulator of cell metabolism, growth, proliferation
and survival (1). mTOR also regulates the expression of slit diaphragm
proteins and cytoskeleton structure in podocytes (2). Since podocytes
are the primer targets of oxidativ stress and renal injury, damage of
these cells leads to proteinuria, which is a sign of most glomerular
diseases (3).
Aim: The aim of this study was to investigate podocyte-specific Rictor
knockout and Raptor-Rictor double knockout mice and to analyze the
role of mTOR signaling pathway in the podocytes by means of these two
mouse models.
Materials and methods: We studied the two mouse populations
mentioned above by observing growth process and registering the renal
function parameter of urinary creatinine-albumin ratio. In addition
Rictor knockout mice were treated with bovin serum albumin.
Results: In our survey we found that podocyte-specific Rictor knockout
mice neither developed proteinuria nor showed histological alterations,
although they responded with significant proteinuria to albumin
overload. Proteinuria and growth restriction could be detected in
Raptor-Rictor knockout mice from 3 to 4 weeks of age. These mice died
at the age of 6 to 12 weeks and developed glomerulosclerosis as well as
disintegrated glomerular architecture.
Conclusions: In our study we found that the synchronous knockout of
both Raptor and Rictor genes in podocytes lead to severe glomerular
phenotype. Our results strengthen the role of mTOR pathway in
podocyte homeostasis, and may contribute to the development of new
medications.
Scientific supervisior:
Prof. Dr. Tobias B. Huber
Medicine IV, Nephrology, University Medical Center
Freiburg, Germany
References:
1. Laplante, M., and Sabatini, D.M. (2009). mTOR signaling at a
glance. J Cell Sci 122, 3589-3594.
2. Vollenbroker, B., George, B., Wolfgart, M., Saleem, M.A.,
Pavenstadt, H., and Weide, T. (2009). mTOR regulates
expression of slit diaphragm proteins and cytoskeleton
structure in podocytes. Am J Physiol Renal Physiol 296, F418426.
3. Pavenstadt, H., Kriz, W., and Kretzler, M. (2003). Cell biology
of the glomerular podocyte. Physiol Rev 83, 253-307.

PROGRESS REPORT ABSTRACTS. MICROBIOLOGY PROGRAM.

Adefela Fagbemi, Nigeria
Naval Biomedical Research Laboratory, Oakland, California
Under the general topic of microbiology, the Office of Naval Research
sponsors basic research in medical microbiology and aerobically. In the
area of medical microbiology, it is important to develop new methods
for the prevention, control and treatment of diseases of importance to
the Navy and the Marine Corps. Before it is possible to develop these
new methods, it is necessary to improve the fundamental research
knowledge of the mechanism by which microorganisms produce disease
in the host. A portion of research described in this report is designed to
provide basic information needed to assist in attainment of the solutions
of infectious diseases in the Navy and Marine Corps. Another portion of
the research in this report is designed to provide information relative to
the effects of physical, chemical and biological factors on the disease
producing microorganisms in the aerosolized state. In these projects,
the effects of the atmosphere or environment on the production,
stability, movement and decay of aerosolized microorganisms is studied
in order to prevent disease transmission among large numbers of men in
confined spaces such as on board Navy vessels and in barracks. Most of

this expertise and research is limited to the staff of the Naval Biomedical
Research Laboratory, Oakland, California.

ETHNIC FEATURES OF ADAPTATION TO A STUDENT'S LIFE.

Kughan Govinden
[email protected]
Nizhny Novgorod State Medical Academy, Russia.
Department of Pathophysiology
Scientific Adviser(s): Professor Tatiana E. Potemina, V.A Churavlaev
Keywords: Adaptation, reactivity, resistance, common cold infection, GIT
disturbances, Russian and International students
Introduction: - Adaptation of each student to new living conditions is
closely linked with reactivity and resistance of organism. Reactivity is
one of the most common properties of an organism which is designed to
react selectively to changed condition of environment and internal
medium. Resistance of organism is faculty of an organism to endeavor
injurious factors. Violations of adaptation are manifested in appearance
of pathological reactions and disease. Among the most frequent are
respiratory and digestive diseases.
Objective: - To compare some parameters of health of students of a
various nationality for an assessment of their adaptation to a student's
life.
Material and methods: - One of the most frequent forms of pathologies
is common cold infections and gastrointestinal (GIT) disturbances.
Comparison of health students before and after admission into the
university for 2nd and 4th year Russian students of medical faculty and
2nd year students of faculty of training of foreign students () is
done. The data was collected via self administered questionnaires
prepared in English and Russian. In total 190 questionnaires (115
Russians, 60 Malaysians, 14 Kenyans and 1 Tanzanian) have been
analyzed.
Results: - All students are ill with common cold infection on average
twice a year and Russian students are ill more often than students from
equatorial latitudes. Russian students of 4th course (51%) have
increased GIT disturbances compared to Russian students of second
course (48.4%). Foreign students (only 36% with increased disturbances)
have fewer complaints than Russian students. The Russian students
complain of an increase in gastrointestinal disturbances than of an
increase common cold infection much more. Some students specifies in
questionnaires of complaints twice and more than average figures. They
are students with the weakened health and adaptation. Regarding
common cold infection, the greatest fraction of such persons has
appeared in Kenyan students (16.7 %). Among Russian students it is
higher for 2nd course (31.2%) compared to 4th year (25.5%). About GIT
disturbances, the fraction of students with the lowered resistance is
more for Malaysian and the Russian second-year students (25 %) and
less for Kenyans and the Russian senior students (14,5 %).
Conclusion: - In summary it is necessary to note that frequency of
common cold infection among students does not depend on their ethnic
accessory. Foreign students have less number of GIT disturbances than
Russians. Considering the condition before admission into academy,
international students mark an increase of number of complaints on
common cold infection and GIT disturbances than Russians.

DISTRESS SYNDROME AND VITAL FORCE OF AFRICANS STUDENTS.

Asogva Innocent Kingsley (Nigeria), Petrova N. (Russia), Omary Nassoro
(Tanzania), Avany Albert Souren (USA), Borsaly Leila (France), Shandor
Farkashdi (Hungary)
Peoples Friendship Univeristy of Russia, Moscow
Medical Faculty, Department of Normal Physiology.
Scientific Adviser(s): Shastun S.A.
Background. Recent experimental studies suggest that there is evidence
for a desynchronization between human heartbeat and respiration.
The research of a functional condition and regulatory abilities of an
organism will be incomplete if not to consider respiratory system which,
as well as a rhythm of heart, reflects a condition of vegetative
regulation.

16 | III
We develop a physiologically plausible model for this cardiorespiratory
desynchronization, and numerically show that the model can exhibit
stable desynchronization during seasonal perturbations.
bjective: to study what challenges to Africans and Russians students
organism give seasonal rhythms and estimate cardiorespiratory
desynchronization during contrast winter-summer seasons.
Materials and Methods: To quantify the cardiorespiratory
desynchronization in phase of respiration and heart rate was assessed.
Researches with first group were carried out on practically healthy 27
African students of the first year education from Nigeria and Tanzania.
Second group were studied with 32 healthy controls subjects from of
Moscow. The basic parameters of cardiovascular system with method of
variability of heart rate (HRV) were investigated. Functions of respiratory
system were studied with by means Spirometer Spirobank D (MIR
Italy). According Kppen Climate Classification System students from
the Central Africa lived in a climatic zone at humid subtropics, and
students from Moscow - in a zone of a mid-continental climate.
Chronobiological desynchronization parameters were studied during
contrast seasons: winter - summer.
Results: Our analytical approach show that: Heart rate variability (HRV)
and Breath Pattern Variability (BPV) was used us as the marker of the
seasonal rhythms among African and Russian Students. High level in
the winter period of capacity low-frequency (LF) component of HRV with
desynchronization Breath Pattern Variability (BPV) (histogram BPV
amodal type) at African students and mid-level same parameters at
Russian students means more good functional capabilities in residents.
In summer time students from both groups have no abnormalities with
cardiorespiratory desynchronization.
Nonlinear least-squares regression and a seasonal phase was assigned
that mesor in relations between minute volume of ventilation (MVV) to
minute volume of blood circulation (MVBC) in winter-time for African
students was 1.80.1 units and for Russian students 1.20.2 units
(P<0.05). This cardiorespiratory desynchronization means that at
residents have reactions with prevails respiratory system, and at the
African students - reaction of cardiovascular system.
Conclusion: Was shown, that high level in the winter period of capacity
low-frequency (LF) component of HRV with desynchronization Breath
Pattern Variability (BPV) (histogram BPV amodal type) at African
students and mid-level same parameters at Russian students means
more good functional capabilities in residents. In summer time students
from both groups have no abnormalities with cardiorespiratory
desynchronization.
These data suggest that summer-time environment protects against
cardiorespiratory desynchronization in African and Russian students
first-year education.

CHARACTERISING THE ROLE OF THE PUTATIVE GENE NMB_0345 IN A

NOVEL PROTEIN SECRETION PATHWAY IN NEISSERIA MENINGITIDIS
SEROGROUP B
Mohammad Fiqry
[email protected]
University of Nottingham, Nottingham, United Kingdom
Scientific Adviser(s): Dr Karl Wooldridge
Keywords: Neisseria meningitidis, NMB_0345, secretion.
Introduction
Neisseria meningitidis infection can cause septicaemia and meningitis,
however, there are no effective vaccine against serogroup B. Many
proteins secreted are involved in virulence, yet have unknown secretion
mechanisms. This led to the hypothesis that there exist secretion
systems yet to be characterised. Bioinformatics analysis predicted the
gene NMB_0345 as involved in one such pathway. NMB_0345 is
homologous to proteins implicated in secretion in other microorganisms
and is annotated as a cell-binding factor. The aims were to; [1.] establish
NMB_0345 as being implicated in protein secretion and adhesion to
human cells, [2.] identify substrates dependent on this secretion
pathway, [3.] express and purify NMB_0345 protein for structuralfunctional analysis, [4.] investigate whether NMB_0345 is conserved
across the Neisserial genus.
Methods

Secreted proteins of mutant strains were harvested (18 hours

incubation in DMEM, 37C, 5% CO2) and compared with wild type using
2D gel electrophoresis. Using Decodon Delta 2D, substrates dependent
on this pathway were identified, and excised for MALDI-TOF and
Orbitrap mass spectrometry. Adhesion and invasion assays were
performed using 1:1 challenge of HEp2 cells (immortal epithelial cells),
and data analysed using SPSS software (unpaired t test). NMB_0345
protein was expressed in recombinant form utilising vectors pQE30 and
pQE70, followed by purification under denatured (100C) and native
conditions (immobilised metal affinity chromatography). Genomic
servers were searched for identical proteins.
Results
A decrease in the concentration of proteins secreted by the mutant was
observed (<55kDa). Adherence and invasion of the mutant to HEp2 cells
were significantly reduced (p<0.001). Purification was successful, except
under denaturing conditions for proteins expressed using pQE30. Similar
genes were found in N. meningitidis A and C (NMA_2142, NMC_1825,
NMC_1797), N. gonorrhoeae (NGO_1656) and N. flavescens
(NEIFL_1761).
Conclusion
This study suggests [1.] existence of a secretion pathway with which
NMB_0345 is involved in transporting proteins across the outer
membrane, [2.] NMB_0345 is important for optimal binding to epithelial
cells, [3.] N-terminus of NMB_0345 protein is folded within its tertiary
structure, [4.] genes related to NMB_0345 are conserved across the
Neisserial genus.

SEASONAL AFFECTIVE DISORDER WITH STUDENTS FROM VARIOUS

CLIMATIC REGIONS.
Petrova N. (Russia), Basharov M. (Russia), Bhooneswar S (Mauritius).,
Avany Albert Souren (USA).
Peoples Friendship Univeristy of Russia, Moscow
Medical Faculty, Department of Normal Physiology.
Scientific Adviser(s): Shastun S.A.
Research Unit has been developing conceptual models and instruments
for research, evaluation and assessment since 1991. In partnership with
the Department of Occupational Therapy and Centre for Health
Promotion at the University of Toronto, the unit carries out quality of
life research that relates to communities, families, and individuals from
a variety of population groups. Taking into account the winter-summer
contrast, the Health-Related Quality of Life (HRQL, SF-36) and seasonal
affective disorder (SAD) were investigated in students from various
geographical regions with different climatic conditions. The study was
composed of two groups of 1st year undergraduate students: African
(17) and Russian (14). They all completed a validated English and
Russian translation of the SF-36 Health Status questionnaire (Perneger
et al., 1995; Leplege et al., 1998). The SF-36 is a multi-purpose health
survey containing only 36 questions and assessing eight parameters, out
of which, three [physical functioning (PF), role physical (RP), bodily pain
(BP)] correlate most strongly with the physical component.
Furthermore they contribute most to the Physical Component Summary
(PCS) score. The mental component correlates best with the mental
health (MH), role emotional (RE) and social functioning (SF) scores,
which also contribute most to the Mental Component Summary (MCS)
score. Two of the scales [vitality (VT) and general health (GH)] have
noteworthy correlations with both components. Thus, the research has
shown that there are authentic distinctions in the African group. When
compared to data for the Russian study group, it can be evaluated that a
change in ecological and social inhabitancy in African students
authentically lowers their HRQL indices. Moreover, symptoms of
Seasonal Affective Disorder (SAD) have been authentically expressed
during the winter period by the African students. SAD is a type of mood
disorder that brings on depression when the seasons change, with its
most common example being winter depression which usually starts in
the late fall or early winter and ends in spring. During the winter-time,
the seasonal rhythm desynchronization of African students under SF-36
and SAD data it is statistically more accentuated.

 . , , , 2011 | 17
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MORPHOLOGICAL CONDITION OF THE TARGET ORGANS (KIDNEY,
HEART) IN CASE OF INDUCED RENOVASCULAR HYPERTENSION AND
USAGE OF THE DIFFERENT TREATMENT OPTIONS (EXPERIMENTAL
RESEARCH)
Lyashchenko O.I.
Crimean State Medical University named after S.I. Georgievskiy, Ukraine,
Simferopol
Medical biology department
Scientific Adviser(s): Krutikov Ye.S., PhD, Lazarev K.L., PhD
Keywords: experimental research, renovascular hypertension, kidney,
heart, treatment
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Abstract: Renal hypertension can be defined as a syndrome which
consists of high blood pressure caused by narrowing of the arteries
supplying the kidneys. It is a form of secondary hypertension which is
widely spread.
Our observations showed that different target organs will react
differently on the different types of treatment.
Morphological condition of the kidney is improved in case of using the
combination of angiotensin-converting enzyme inhibitors and calcium
channel blockers, but the hearts morphological condition was better in
case of monotherapy (calcium channel blockers)."
"Introduction.
Renal hypertension can be defined as a syndrome which consists of high
blood pressure caused by narrowing of the arteries supplying the
kidneys. It is a form of secondary hypertension which is the most widely
spread. Morphological features of the renovascular hypertension have
already been fully investigated and agreed upon, but the opinions of an
influence of the different treatment options on the structure of the
kidney and heart vary greatly.
The aim of our research was to investigate the character of
morphological changes that take place in the kidney and heart in case of
induced renovascular hypertension and usage of the different treatment
options.
Materials and methods. Our research was made on 40 Wistar rats
(males and females); weight 74-110g (the age of the rats 1 month old).
Ten (10) rats served as a control. For solving this problem we created an
experiment. We induced renovascular hypertension on all of the rats
that were under experiment. The treatment started after three month
of proved hypertension condition in rats. Pharmacological correction
was used during 3 month. In the first experimental group we used
angiotensin-converting enzyme inhibitors, in the second group calcium
channel blockers, in third combined action of the above mentioned
drugs. Histological (light microscopic and electron microscopic) and
morph metrical researches were used to evaluate the degree of changes
that take place in the heart and kidney.
Results. According to the results received, morphological condition of
the kidney was significantly improved in the third experimental group
(glomerular capsules are thickened but showed no signs of atrophy;
glomerular cells nuclei have irregular shape which indicates the
compensatory hypertrophy process; glomeruli blood supply is
increased). Morphological condition of the heart showed an
improvement in the second experimental group (clearly marked signs of
hypertrophy (big polyploid nuclei in the myocardium of the left
ventricle, prolonged shape of the cells in the epicardium of the left
ventricle)).
Conclusions. Our observations showed that different target organs will
react differently on the different types of treatment. Morphological
condition of the kidney is improved in case of using the combination of
angiotensin-converting enzyme inhibitors and calcium channel blockers,

but the hearts morphological condition was better in case of

monotherapy (calcium channel blockers).

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DEPENDENCE OF EFFICIENCT THERAPY OF HIV-INFECTION ON INITIAL
LEVEL CD4-LYMPHOCYTES
Emerole K. T, Sita N. P.
Peoples' Friendship University of Russia, Russia, Moscow
The Faculty of Medicine, Department of of infectious diseases
Scientific Adviser(s): Konnov V.V, PhD, prof. Kozevnikova G.M., PhD
Keywords: slow hiv-infection, cd4-lymphocytes, efficiency therapy
: , , cd4-
Abstract: Based on the study, given that the patients were given
standard scheme of therapy including 2 preparations from the
nuclozide group and the inhibitors of transcriptaz , on the grounds of the
given therapy , there were decreases in concentration of RNA HIV in the
blood within patients of the given groups, which median by 6 months of
treatment reached a non- defined level (less than 40 copies in blood ml)
. A clear difference in the decrease in virus load in both groups was not
revealed. However it was noticed that an increased level of CD4lymphocytes was authentically more intensively within the first 9
months of therapy within patients who had higher indicators of the
immune status at the start. By the end of the first year of therapy the
median of level of CD4-lymphocytes was: 291 (17 %) cells in mkl blood in
the1st group and 309 (23 %) in 2 group.
All patients who were in clinical progressive stage at the start of the
therapy, acheived remission with the help of antiretroviral drugs and
treatment of secondary diseses
Conclusions
Patients with Hiv infections with very low CD4 lymphocytes had an
increase in virus load, and oftenly suffered symptoms of critical
secondary diseases. With the help of antiretroviral therapy a clear
difference in the deep decrease of virus load in dependence of initial cd4
cells level was not noticed. The median of virus loading reached a nondefined level by 6 month of therapy
Within first 9 months of antiretroviral therapy within patients with
higher initial level of CD4-lymphocytes, more intensive increase was
noticed, by 12 months immunity restoration in this group was achieved
(309 (23 %) cells/mkl in 2 group, 291 (17 %) in 1st group).

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18 | III

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ESTOMATION OF EFFICIENCY OF A MEDICINE TROMETALOL H ON
COMPLEX TREATMENT OF A GOUT COMPLICATED NEPTHROPATHY
AND UROLITHIASIS
Annenkov A.V., Israfilov M.N.
Peoples Friendship University of Russia, Russia, Moscow
The Faculty of Medicine, Department of urology and operative
nephrology
Scientific Adviser(s): prof. Avdoshin V.P., PhD
Keywords: gouty nephropathy, Trometamol, uric acid, glomerular
filtration rate
: , ,
, ,
Abstract: Studying of efficiency of a medicine Trometamol in complex
treatment of a gout complicated nephropathy.Material and methods. 38
patients articipated in research at the age from 42 till 85 years with the
diagnosis a gout, gouty nephropathy. Duration of disease was from 2 up
to 18 years.Results. After the therapy at overwhelming majority of
patients decrease in indicators of uric acid of blood is noted.
Improvement of function of kidneys was shown by normalisation of
indicators of urea and creatinine in blood serum, increase in glomerular
filtration rate.


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 . , , , 2011 | 19
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RESEARCH OF TREATMENT-AND-PROPHYLACTIC PASTES AT
TREATMENT AN INFLAMMATION OF GUMS
Borokhova I.M, Jeludkova.A.U
Peoples Friendship University of Russia, Russia, Moscow
The Faculty of Medicine ,Department of propedeutics of stomatological
diseases
Scientific Adviser(s): prof. V.S Bulgakov, PhD, Vereskova M.A.,
Shapovalova S.V.
Keywords: research, anti-inflammatory tooth-pastes
: ,

Abstract: We have made primary research of tooth-pastes, then having

examined 25 patients and taking from them a biological material
secondary research of tooth-pastes on their anti-inflammatory effect
has been made


( 95%). ,
,
5 ,
,
.
,


.

( 60%). ,
10-20 ,
.

. 10
.



,

.

. 6

: 32 , lacalut aktiv, splat

, blend-a-med pro expert, paradontax , aquafresh 3+.
- ,
S.sangius. ,
,
,

S.sangius .
.
, aquafresh 3+
. ,

,
,
21 17
21.
.


.
, ,

aquafresh 3+.
paradontax,
- splat .

,
,
76% (16 21
)
. 24%,

,
.

.

.., .., ..
[email protected]
, ,

() (): .., ..
ANTITUMOR EFFICACY OF LOW-DOSE X-RAY USING LUNG LEWIS
CARCINOMA OF MICE
Buldakov M.A., Klimov I.A., Kutenkov O.P.
Tomsk Cancer Research Institute Siberian Branch of the Russian
Academy of Medical Science
Department of immunology
Scientific Adviser(s): Cherdyntseva N.V., Bolshakov M.A.
Keywords: low-dose X-ray, cancer therapy
: ,

Abstract: Reducing side-effects of X-ray cancer therapy is the most

important problem of oncology. One way is to decrease dose with saving
antitumor effects. It could be reached by the repetitively-pulsed X-ray
with nanosecond pulse duration. The results of experimental are
evidence that pulsed X-ray at the dose rate 6 - 20 mGy inhibits growth of
lung Lewis carcinoma of mice at 15 - 30% and reduced metastasis at
30%. So, pulsed X-ray possessed an a potential to promote low-dose
cancer therapy.
.

,

.
, ,

20 | III
,
. , () 95%

in vitro.
.
.
.
, 57Bl6
.
.
-150,

, . , ( 4 ;
160 ; 0,3 - 1,5 ).
60 .
.



.
3 , 50-60%
10 (1,8
/), 13 (54 /), 16 (6 /),
3
.
12 , 60 40 .
6- 13-
. 10-

. 11-
, 10 16 ,
,
18%. , 15-
, 10 13 ,
16 .
,
21- ,
,
10 1,8 /
( 24 )

, 13 31 % .
,
,
.
. in vitro

in vivo.
, 13%.


, .

. .
[email protected]
, ,
,

() (): ... .
COMPARISON OF THE EFFECTIVENESS OF ALKALIFY TROMETAMOL
AND SODIUM BICARBONATE PATIENTS WITH DEFICIT LEVEL
BICARBONATE
Vovk. A.S.
People's Friendship University of Russia, Russia, Moscow
The Faculty of Medicine, Department of anaesthesiology and
resuscitation
Scientific Adviser(s): Moroz V.A., PhD

Keywords: Tham, sodium bicarbonate, acid base disturbance

: , ,
-
Abstract: Acid base disturbance is important to intensivists, who are
routinely faced with acid base abnormalities in practice. The most
frequently for the correction of metabolic acidosis used sodium
bicarbonate and trometamol.
-
.

.
, .
:
( )
- 2-
64.
:
:
20
,
25 89 .
- ()
.
: pH, pC2, pO2, BE, HCO3-, SaO2.
1, 3 24
. 1,0
2,0 .


.

:
,,,
,
,
.
10
,
29
78 .
1,5 2,5 .

.
: ,
,

.

,
.
:
, ,
.

:
IGE
..
[email protected]

, ,

() (): ..., . ..
ON THE ROLE OF NOVEL TYPES OF HISTAMINE RECEPTORS IN THE
REGULATION OF IGE
Dorofeeva Y.R.
Kuban State Medical University, Russia, Krasnodar
The Faculty of Medicine, Department of Clinical Immunology, Allergy
and Laboratory Diagnostics
Scientific Adviser(s): Khanferyan R.A., PhD
Keywords: allergy, histamine, histamine receptors, immunoglobulin E
: , , ,
E

: 1, 2, 3 4.
.

 . , , , 2011 | 21
(3)
,
,
, ,
, , .
4 ,
.

4 3
.
58%.
3/4
,
IgE.
3/4
IgE
() 12 (5
) in
vitro 9 .
3/4 .
( Ki = 0,26 nM).
IgE
(ELIZA).

, (10-8 )
IgE, (10-5)
IgE.
3/4
IgE
, ,
.
3/4 ,

,

.
IgE
,
(<0,01) 3/4
(10-5).

3/4
, IgE .

IgE,
,
,


.

.., .., .., ..
[email protected]
.
.., ,
- ,

() (): ..., ..
THE RESOURCES OF CELL VITAL COMPUTER MORPHOMETRY FOR
EVOLUATION OF PLATELET HEMOSTASIS
Kastrikina I.S., Kolosova E.N., Lifenko R.A., Agadzhanjan B.Y.
Russian State Medical University, Moscow, Russia
Scientific clinical center of gerontology, Department of computer
cytomorphometry
Scientific Adviser(s): prof. Vasilenko I.A., PhD

Keywords: hemostasis, platelet, immune thrombocytopenic purpura,

morphometry

: , ,
,
Abstract: The purpose of this study was to evaluate the diagnostic
effectuality of vital computer morphometry for non-invasive
investigation of platelets. 30 healthy volunteers and 50 patients with
immune thrombocytopenic purpura (ITP) were investigated. Morphofunctional status of platelets we determined by express-method of vital
computer morphometry using computer phase-inteference microscope
Cytoscan. Our data demonstrate the high degree of platelet
population heterogeneity for ITP: the objective distinctions in the cell
size and morphology structure
()
, (
)

. ,

. ,
,
.
:
.
50 29 69 (
46,35,7 ) 3
5 , 5000/ 120
000/. 30
.
-

,
,
)

(
GP-IIb/IIIa)

ELISA.
:

4
,
: - 1 (
62%),
- 2 3 ( 21 12%)
- - 4 ( 5%).

: 1 48%,
50% (40% 10% 2 3 ,
). .
,
: - 2,6
0,8 mkm; - 8,0 3,0 mkm; - 1,2 0,5 mkm; 4,7 3,9 mkm2; 1,8 1,3 mkm3.
3,80,8mkm,
- 10,53,0mkm, - 7,43,5mkm2 3,92,5mkm3, ,
, 1,20,7mkm.

200% 980%



- (r=0,521
r=-0,470, , p<0,05),

.
,


,

22 | III

.
,
.

. .
[email protected]
, ,
,

() (): ... .
APOPTOSIS AND ARCHITECTONICAL CHANGES OF MYOCARD IN ACUTE
LEFT VENTRICLE OVERLOAD
Korshunova A. Yu.
Peoples' Friendship University of Russia, Russia, Moscow
The Faculty of Medicine, Department of General Pathology and
Pathophysiology
Scientific Adviser(s): Blagonravov M.L., PhD
Keywords: apoptosis, cardiomyocytes, morphology, acute, aorta,
stenosis, left ventricle
: , , , ,
, ,
Abstract: ute hemodynamic overload of the left ventricle was
modeled on rabbits by narrowing the ascending aorta. On the 1, 3, and 5
days of the onset of hemodynamic overload the hearts were extirpated
and light microscopic morphometry of myocardial sections was carried
out. The rate of cardiomyocytic apoptosis was determined by calculating
the morphologically changed nuclei in the extracellular space. It was
found that the rate of cardiomyocytic apoptosis was increasing during
the whole experiment.


.
,
.

,
.

.
:
()
, .

, 33,5 . 4
5 : 1 ( ) 3
(
1, 3 5 ).

1/3
.
.

( 86/609/).

.
( , .%)
, , ,
..
.
(
,
)
:

t
(
0,05).
.
1-
.
,
.
.
( 66,602,06
46,80
3,11
.%),

( 26,901,79 35,732,35 .%),

.

( 0,030,03 0,470,12 .%) ( 0,100,10
0,540,11 %).
3-

( 47,503,44 .%), , -,
.

( 1,600,29 .%), (
0,620,08%), (
41,402,72 .%).
( 2,170,34 1,730,28.%) ( 12,072,28
5,331,08.%) .
5-
( 44,333,93 .%)
( 8,631,52 .%)
3- . ,
:
1,5
( 2,500,36 .%).
:
1-
.

..
[email protected]
, ,
,
() (): ... ..
DYNAMICS OF INDICATORS OF HEART RATE VARIABILITY AT THERMAL
AND COLD INFLUENCE ON A HUMAN BODY
Lazko M.V.
Peoples' Friendship University of Russia, Russia, Moscow
Faculty of Medicine, Department of normal physiology
Scientific Adviser(s): Severin A.E., PhD
Keywords: variability of a warm rhythm, thermal influence, cold
influence
: ,
,
Abstract: At thermal, and at cold influences initial reaction of a cardiac
rhythm consisted in disorder increase R-R intervals (SDNN) and decrease
in amplitude of a fashion (). In 3-5 minutes after the influence
beginning, especially after action of cold SDNN essentially went down,
and Amo, and stress-index essentially increased.
Thus, initial reaction of indicators testifies to nonspecific response
to action of external stimulus. Duration of such reaction averages 3-5
minutes. The specific changes of indicators reflecting specificity of
influence occur during later period.



( .., ..,1998, .., 1997).

 . , , , 2011 | 23

,
.
,
, ,
,
( ..1976, 1998,
2005).
,
, ( ..,
.., .., 2000).
,
,

. ,

, ,
, .

()
,
.

8 2 (3 5 ).
5
,
(37-40 .) (0 .)
5 ,
1 .
, ,

(SDNN)
() . 3-5
,
SDNN , , -
.
,

.
3-5 . ,

.

CANDIDA
ALBICANS
.., ..
[email protected]
, ,

,
() (): ... . ., ...
. .
THE DAILY DYNAMIC OF CANDIDA ALBICANS PHOSPHOLIPASE
ACTIVITY
Maschkina N.A., Nyesterowa O.S.
Tyumen State Medical Academy, Russia, Tyumen
The Faculty of Pediatric, Department of microbiology
Scientific Adviser(s): Timokhina T.H., PhD, Nikolenko M.V., PhD
Keywords: biorhythm, phospholipasa, Candida
: , Candida albicans,
Abstract: Experimental are found daily changes phospholipase activity
depositedon strain and clinical isolates of Candida albicans. The change
of profile of rhythm, a daily average, the amplitude of oscillations of the
enzyme activity of fungi isolated from patients with candidosis.
. ,
,

.
Candida,
,

, .
andida . albicans
5080%
70% , 90%
5070% .

.


.
(,
, ).
C. Albicans
.

. .albicans
4 : 1, 2; ; ;
pH 3.6; 5.6; 8.6. 2
- .

,
,
,
, .

. ,

,
,

.
albicans.

C.albicans
:
1.

C.albicans
2.
,

3.

,
:
1.

C.albicans
2.

,


3.

C.albicans

:
1.

C. albicans
2.

:

2008 .
Candida albicans (C. albicans) 24433
, : ,
, 102 106
.

Auxacolor 2 Bio-Rad.
.

... .., .. ...
..

(W. Nelsen, t al, 1979).
C.albicans
. 6 , 486 .
:

24 | III

,

,
.


.
C.albicans 24433

-8.00,
-16.00.
.
.
,
102 ,
, .

.
C.albicans,
,
, , ,
. ,
,

.
.
, 106 ,


.

.
.

.
, ,
.
, ,
.
.

.
, ,
.
.
.

.
, ,
102 4.00,
.
.
,
.
, , 102
,
, .
. ,
:
:
1.
C. albicans
.
2.
C. lbicans
,
.
3.

C.albicans, ( ), .
4.

.

.., .., .., ..,
..
[email protected]
- , ,

() (): ... ..
DIFFERENTIAL METHYLATION SCREENING OF GENOMES IN BREAST
CANCER SAMPLES
Rudenko V.V., Kuznetsova E.B., Tanas A.S., Zaletayev D.V., Strelnikov
V.V.
Research Centre for Medical Genetics, Russian Academy of Medical
Sciences, Russia, Moscow
Laboratory of Epigenetics
Scientific Adviser(s): Strelnikov V.V., PhD
Keywords: amplification of intermethylated sites, differential
methylation screening of genomes, methylation-sensitive arbitrarily
primed
PCR,
in
silico
modeling
: ,
, ,
in
silico
Abstract: Hypermethylation of promoter CpG islands is strongly
correlated to transcriptional gene silencing and epigenetic maintenance
of the silenced state. Our method of screening of differential
methylation has allowed us to identify abnormal methylation of CpG
islands associated with 22 genes (AX746725, AK127124, TMEM176A,
TMEM176B, FOXM1, C12orf32, KIAA1324L, C2CD2, ITGA9, IQSEC2,
PHF15, PURB, ATMIN, ASCL2, EST CN371412, RORA, DOCK6, DCLRE1C,
USP38, CBFA2T3, KCNH8, THRB) in breast cancer samples.
:
()
- .
:

,
. ,
,

. ,

AIMS in silico.
120 .
: CpG CUX1 TAF4, MAD1L1 3'CpG- ZBTB4,
.
CpG 22 (AX746725, AK127124, TMEM176A, TMEM176B,
FOXM1, C12orf32, KIAA1324L, C2CD2, ITGA9, IQSEC2, PHF15, PURB,
ATMIN, ASCL2, EST CN371412, RORA, DOCK6, DCLRE1C, USP38,
CBFA2T3, KCNH8, THRB), CpG-
.
,
, 14 CpG-
(AX746725, AK127124; TMEM176A, TMEM176B; FOXM1, KIAA1324L,
C2CD2, ITGA9, EST CN371412, RORA, DOCK6, DCLRE1C, USP38,
CBFA2T3, KCNH8, THRB).
2% 92%.

, 5

ccg 3
gcg. ( ccg)

: KIAA1324L ATP2B4
2,
PHF15, IQSEC2, C2CD2, AX746725/AK127124, ATMIN, PURB

CpG-
13q32.1

2-

 . , , , 2011 | 25
2- ,
IQSEC2, CpG- 13q32.1 PURB 4 .


.

1 4 ,
. ,
gcg
DOCK6, KCNH8
.
KCNH8,
DOCK6, 3- DCLRE1C, CBFA2T3.
KCNH8, DOCK6, DCLRE1C, CBFA2T3
2 3
.
.
T1 (<2) 0.460.14,
T2 (25) 0.680.22 (p<0.01),
r=0.48 (p<0.001).
: ,

-

.
,
,
,

.., ..
[email protected]
..,
,
,
() (): ..., ..
ORGANOTYPING RETINA CULTURE AS A MODEL FOR ESTIMATE STEM
CELL TRANSPLANTATION EFFECTIVENESS IN DAMAGED EYE RETINA
Sergeev S.A., Khramova Y.V.
Lomonosov Moscow State University, Russia, Moscow
Faculty of Biology, Embryology department
Scientific Adviser(s): Semenova M.L., PhD
Keywords: Stem cells in vitro transplantation, organotyping culture
: , In vitro,

Abstract: In this work the organotyping retina culture have been used
for the purpose of MMSC transdifferentiation obtaining and their ability
to engrafting in host retina demonstrating. This method allows detailed
description of transplanted cells behavior. ASM assay had showed
MMSC transdifferentiation. Our date demonstrate that suprachoroidal
NSPC transplantation may not improve retina reparation versus their
injection in to the neuroretina. ESC has suspicious affectivenes for retina
reparation.


.
,
,

,

in vitro.
ex vivo
,
.

DMEM/F12 20/ FGF EGF, 7%
FCS, , 12 N2.
EGFP+ () 4-
, / (),
10003000 0,1
. -
- Solver BIO Olympus (), 1001007 3
Nova STATISTICA 8.0.
(p<0,01)
, ,
;
2,5 0,06
4- .
(20, 0,5 200)

, EGFP+ ,
.

(
(p<0,05) ) 3-
, .

, (600
,
1000
,
3000
),

7
90%, 56% 27%
.

(p<0,05)

.


,
-
. GFP
, ,
.
, ex vivo

;


;

;

;

,

.
2009 2013 .

.., .., .., ..,
..
[email protected]
- , , ;

.. , ,

() (): ... ..
ALGORITHMS AND SOFTWARE FOR THE DIFFERENTIAL METHYLATION
SCREENING OF CANCER GENOMES

26 | III
Tanas A.S., Rudenko V.V., Kuznetsova E.B., Strelnikov V.V., Zaletaev D.V.
Research Centre for Medical Genetics, Russian Academy of Medical
Sciences, Russia, Moscow;
I.M. Sechenov First Moscow State Medical University, Russia, Moscow
Epigenetics Laboratory
Scientific Adviser(s): Strelnikov V.V., PhD
Keywords: algorithms and computer programmes, computer modeling
of biomedical experiments, DNA methylation, differential methylation
screening of genomes
: ,
-
, ,

Abstract: We have developed a synthetic algorithm of DNA differential
methylation screening and identified the key stages of analysis that
require upgrading. Laboratory protocol design was supported by
computer simulation of the experiments (AIMS in silico program).
Comparison and genomic mapping of the epigenomic representations
elements were performed using PeakPick computer program in
combination with restrictase mapping methods. The effectiveness of the
novel method for differential methylation screening has been
demonstrated in the study of various forms of cancer.

.
,

.

:

,
.

, ,
,

.

,
.

.


.

, .
, ,

.

.


( AIMS in silico).

.
,

,
. ,

.


PeakPick
.

,

(),

.
,
-
-, .

"" "" ( 02.740.11.0089).

.., .., ..
[email protected]
, ,
,

() (): ... .., ...
.., ... ..
MORPHOMETRIC CHARACTERISTICS OF THE FUNCTIONAL ZONES OD
SPLEEN IN EXPERIMANTSL ACUTE DESTRUCTIVE PANCREATITIS
Tishkina E.W., Fedukova A.S., Fedorovsky A.M.
Kirov State Medical Academy, Russia, Kirov
Pediatrics faculty, Department of Human Anatomy with course of
topographic anatomy
Scientific Adviser(s): Rasputin P.G., MD, Andreeva S.D., PhD,
Fedorovskay N.S., PhD
Keywords: spleen, immunohistochemistry, acute destructive pancreatitis
: , ,

Abstract: The condition of the white pulp in white mongrel rats with
induced acute destructive pancreatitis (ADP) was estimated. It is
ascertained that in the 1 hour after the modelling of ADP a significant
lymphatization of the white pulp (5 times more than in the intact rats)
took place. Being reduced in 24 hours (probably due to outcome to the
peripheral blood and to the focuses of inflammation) it rose again in 3
days and kept being high till the end of the experiment (14 days) that
shows tension of the immune response.

,
,
, .
,
,
.

.



.


.. 30
180220.
.

1 . 1 1, 3, 7, 14-
, ( 5
) ,
,
. CD3 (Dako).

 . , , , 2011 | 27
-.

Biostat <0,05.
, 1


0,0090,001 0,0880,006
.
23,66,6 115,629,5,

51,23,0,
2 (<0,05),
3,5
(0,0320,002 ).


0,063 0,01.
101,024,6, 4 , (<0,05).


(109,817,4),
7,5
(0,0680,01 ).

14
0,0550,006 ,
88,610,1(<0,05).
,
1 .
1
.


, 1 .

,
.

.., .., ..
[email protected]
, ,
,
() (): ..., , -.
.
MAXIMUM OXYGEN CONSUMPTION AT THE CONDITIONS OF HYPOXIA
Shatalova E.O., Zajakina N.V., Padygina S.A.
Peoples' Friendship University of Russia, Russia, Moscow
The Faculty of Medicine, Department of normal physiology
Scientific Adviser(s): Severin A.E., PhD
Keywords: physical training, hypoxia, cardiovascular system, respiratory
system, cleansed and oxygenated blood
: ,
,

Abstract: To study maximum level of oxygen consumption at the

conditions of hypoxia 15 RPFU students at the age of 19-20 were
monitored. Results indicate the high activity of cardiovascular and
respiratory systems of organism in answer to hypoxia.

,
,

. ( .., 1999, 2003; ..,
1998; .., 1993). ,

( .., 1976, 2008).

:
- ()


,
.
-

-
,
() ,
().

.

- ,
15 ,
:, , V2, V2. .

1
/ 300

110 85 . . .
(1000 )
.

.
,
.
,
,
,
,
. : , , %
, , ,

.

.
,
, , :
1.
,
() .. . (1986).

,
,
,
,

.
2.

.

,
. 2
, ,
110-130 . . .
3. ,
,
,
,
.

28 | III

.

- -
.., .., .., ..,
.., ..
[email protected]
, , ,
, ,
-

() (): ..., ..
GENERAL H-REFLEX AND M-WAVE PATTERNS CHANGES AFTER COURSE
OF INTERMITTENT HYPOXIA
Shilov A.S., Anoufriev A.N., Kornienkov M.T., Ostyakov I.I., Ponomar E.J.,
Ulyasheva E.A.
Syktyvkar State University, Russia, Syktyvkar,
Faculty of Psychology, Social Work and Physical Education, Department
of theoretical and medico-biological principles of physical training
Scientific Adviser(s): Bocharov M.I.

, PhD

Keywords: hypoxia, H-reflex, postural muscles

: , -,
Abstract: Series of studies performed on neurologically healthy males
(n=28) who had the course of intermittent hypoxia (IH) (16 days, 12.3%
O2). In a control study, on 1, 7 and 16 day readaptation assessed the
temporal and amplitude characteristics of the monosynaptic H-reflex
and the M-response. This changes the motor component of response to
direct electrical stimulation: 1-day rehabilitation lowers the threshold of
excitability of motor units m. soleus and increases the range of
maximum forces call their recruiting, retaining this focus up to 16 days,
on day 1 the number of excitable motor units at threshold stimulation.

(n=28),

() (16 , 12,3% O2).

, 1, 7 16
M-. H- M-
m. soleus .
Ia n. tibialis

12 50 (20 , 2 ,
0,1 , 0.7 ).

,
H- M-,
-.
Mmax- max- m. soleus
,
,
1- 16-
.
m. soleus
,
.

.
, , ( )

, 1-7 ,
. ,
( 16- )

m.
soleus. ,
: 1-
-,

16- ; 16-

Ia.
: 1-
m. soleus

, 16-
; 1-
.

.., ..
[email protected]
, ,

() (): ... ..
CHANGES IN THE ACTIVITY OF CATALASE IN BLOOD AND TISSUE
HOMOGENATES OF RATS UNDER THE INFLUENCE OF ALCOHOL AND
ENERGY DRINKS
Ezugbaya B.S., Djidjichia K.M.
Kuban State Medical University, Russia, Krasnodar
Department of general and clinical patofiziologii
Scientific Adviser(s): Gybareva E.A., PhD
Keywords: catalase, liver, kidney, heart, blood, homogenates, alcohol,
energy drinks
: , , , , ,
, ,
Abstract:


,
,
.
. , ,
: - RedBull, - - Jaguar
.
. 15
- , 200 .
.
1 .
,
..,
..* .., .., .., 1988+
* .., .., ..,
.., .., 2006+.
. , , Jaguar
:
29%, - 12,5%, - 40%, 38%. ,
Red-bull :
24%, - 12,5%, 40% , - 34%. ,
, :
29%, - 13%, -
32%, - 38%.
. ,
,
,
.

..
[email protected]
, ,

 . , , , 2011 | 29

,

() (): ... .., ... ..
EFFECTS OD ADENOSINE ON DENDRITIC CELLS PROANGIOGENIC AND
IMMUNOSUPRESSIVE FACTORS EXPRESSION
Yuryeva K.S.
Siberian State Medical University, Russia, Tomsk
Central Laboratory of Scientific Research, Department of molecular
biology
Scientific Adviser(s): Ryzhov S.V., PhD, Sazonov A.E., PhD
Keywords: adenosine, cell therapy, paracrine factors
: , ,

Abstract: We have studied effects of adenosine receptors stimulation on

bone marrow derived cells (BMCs). BMC were isolated from 57BL/6
mice and cultured in the absence or presence of adenosine analogue.
We have shown that adenosine differentiated DCs had increased
arginase activity (108021299 vs 3114298.1 U/1million cells, =0.02)
and nearly two-fold increase in VEGF, IL-6, CXCL1 production compared
to unstimulated samples. We believe that adenosine-differentiated
therapeutic cell will significantly improve tissue regeneration after
myocardial infarction.
, ,

. ,

.
,

,

in vivo,
. , ,
,
,
.



.
.

10 57BL/6.
RPMI 10/ -4 10/
-

, (100
NECA) DMSO. 6- ,

5/. 24
(VEGF),
-6 (-6), CXCL1
.

L-

NO-
.

.
. ,
,
NECA ()
.
,
NO- .
,
NO-
(), NECA
(352,615,3 413,519,4 / ,
=0,0242). (3114298,1 /1 )
, (108021299 /1 ,
=0,02). ,
.

,

, .

NO-, ,
.


: VEGF (1.380.18 vs 0.690.12/, =0,005),
CXCL1 (18.73.1 vs 8.51.4/), =0.0055), -6 (39.174.93 vs
19.521.7/, =0.001)

,
.


.
.
,

,
,
.

.., .., .., ..,
.., .., ..
[email protected]
, ,

- , ; , .
, ,

() (): ... .., ... ..
ANTIGENIC PHENOTYPE AND SECRETION OF PARACRINE FACTORS AT
THE INITIAL STAGE OF DENDRITIC CELL DIFFERENTIATION IN PATIENTS
WITH BRONCHIAL ASTHMA
Yakovleva Yu.A., Korotkaya E.V., Yuryeva K.S., Goremykin K.V., Saltikova
I.V., Kulikov Ye.S., Fedorova O.S.
Siberian State Medical University, Russia, Tomsk
The Faculty of Life-science, Central research laboratory;
Vanderbilt University, Nashville, Tennessee, USA
Department of Cardiovascular Medicine
Scientific Adviser(s): Ryzhov S.V., PhD, Sazonov A.E., PhD
Keywords: adenosine, adenosine receptors, bronchial asthma, dendritic
cells, monocytes, cytokines.
: , ,
, , , .

Abstract: Local concentrations of adenosine reach high physiologically

relevant levels in pathological conditions. Stimulation of adenosine
receptors skews dendritic cells (DC) differentiation toward a distinct cell
population characterized by expression CD14+/CD1a-/CD209+
phenotype & high levels of IL-6, IL-8 & VEGF. We have found that
stimulation of adenosine receptors further enhances percentage of
these cells from patients with asthma if compare to healthy volunteers.

()

,

. ()
:
()
Th2 *Lambrecht B., 2008+.
() ,
.
() (1,2,2,3). ,

30 | III

.
.
()
(-6, -8) (VEGF)

().
.
33 19 51 .

(
. , ..).
, GINA
(2006 .). 21 .

.


- (, ).

(SIGMA,
).
RPMI -4 (RDSystems, ) (RDSystems, ) 2- 38 .
NECA (5'N-) (SIGMA, ).
,

-
: CD1a-FITC (Dako, ), CD14-PE,
CD209-PerCP-y 5.5 (BDFarmgen, ),
FACS Calibur (BDBiosciences, ).
-6, -8, VEGF

( , ).

SPSS Statistics 17.0.

-; ..
,

U- -,
(
<0,05).
. ,
CD14+/CD1a-/CD209+ 1,35% (0,59%
5,785%) 4,12% (1,62%6,94%) (p<0,05) 4,16% (0,695%
14,515%) 6,09% (1,105%22,205%) (p<0,05) .
-6 5,67 /
(2,169,28, /) 2,95 / (1,624,76, /) ; -8 26,9
/ (9,76 40,01, /) 15,49 / (7,17 22,64,
/) (p<0,05).
VEGF 27,93 /
(10,99171,93, /) 250,85 / (106,79424,09 /) (p<0,05)
71,97 / (22,3113,05, /) 174,62 / (111,72
384,03 /) (p<0,05).
.
,
.
1.5,
02.740.11.5150

.., .., ..
.
, .
BIORHYTHMOLOGICAL FEATURES OF SINGLE KIDNEY PROLIFERATIVE
PROCESSES AFTER RESECTION OF
PART OF IT
Muradov, A.A., Mukhamedova S.G., Naimov N.M.
Tajik State Medical University named after Abuali ibni Sino
Dushanbe

Key words: kidney, nephrectomy, resection, circadian rhythm of mitosis.

: , , ,
.
Summary: it was shown that in the kidney remaining after nephrectomy
and resection of part in the unfolding of compensatory reactions as
hyperplasia, the temporal organization of this process is retained and is
characterized by maximum intensity desynchronosis (the inversion, the
shifts of parameters which make up the rhythm of the curve),
corresponding to the strength of the impact of stress factors.


.
96
105-120. 2 :
72 ,
(
)
24 .
.
.

. ( 3
) 3 (6, 9, 12, 15, 18, 21, 24, 3)
. 10%
.
-.


(), (%). 8 - 12
.
( .. ., 1979).

Statistica. ,
0,05.
, ,
: 1 - 2 ; 6 13
; 30 - 5 ( P<0,001).
1
,
(09) 9 45 , -
(21).
(24) 10 30 ,
- (12). ,
.
1,1 .
,
, , (13%)
(13%).
6-
, :
(06 ),
- (24 ). :
1,3 ,
1 , 2 .
.
, , ,
,
,
, ,
(1 ),
, ,
30
.

-

.., ..
.

 . , , , 2011 | 31
.
ACTIVENESS OF STRESS-REALIZING SYSTEM IN EVALUATION OF
HUMAN ADAPTATION ABILITIES
Khakimova M. M., Halimova F.T.
Tajik State Medical University named after Abuali ibni Sino
Dushanbe
Keywords: stress, adaptation, sympathoadrenal system, electrolytes,
cortisol, glucose, saliva, and beta adrenoreactivates of erythrocytes.
: , , - ,
, , , ,
.
Summary: a study of students adaptation abilities to emotional stress
and of people living in high-grade anthropotechnogenic load allowed
revealing a number of criteria quantitatively characterizing the
activeness of the sympathoadrenal system (main part of the stressrealizing system).




.
, ,

.
, ,
.

, .

,
.
,
(),
- .
,
,

.
, 59 80%

, , ,
.

, ,
.


- .
250
168

. -
,
, ,
. , 90%
-
(-) 2,0 20,0 . .
-

.
- 60
.
:
(
),
, (
), ( ),
.

(),

. , 4 ,

,
.

,

,
,

.
,

- .


-
,
,
. 1
,
,
- .
,
III . ,
IV ,

- .
, ,

, , ,
.
,
:
,

( 10 ) ( 1,7 ). ,
(-)

.
, ,
,


-.
-
,



.

,
.
,
,
, ,

, :

) ;


;

.



,
.

32 | III

.
.
, .
() (): ... ..
EVALUATION OF HUMAN ADAPTATION ABILITIES ON CHANGE OF
CONCENTRATION OF GLUCOSE AND CORTISOL IN HUMAN SALIVA.
Saburzoda M.
Tajik State Medical University named after Abuali ibni Sino
Scientific Adviser(s): PhD, Halimova F.T.
Keywords: ecopathogenic factors, glucose, cortisol, saliva, adaptation
and dysadaptation.
: , , , ,
.
Abstract: examined 148 men with different periods of residence in a
high-grade anthropotechnogenic load conditions. All of the examinees
were determined glucose and cortisol concentration in saliva. The
analysis revealed 4 types of speakers, each of which reflects some
degree of stress functional systems.



,
( ..,
2007; ..,2005; Levine A et all., 2006).

,
(Fairchild
Get all. 2008).
,
,

. ,

(Nicolson N.).


. 148

.


.

.

,
,
10 ( 0,068
/ 0,685 /), 1,7 .(
14,6 / 23,81 /).
,
.

,
,

,
,
, ,

.
,

.
,

. ,
.

,


.

4 ,
.
,
( 2 )
( 18,5 ).
,
,

.
,


. ,
( )
( 2,6 )
.
,


. ,




,
.

-

..
[email protected]
, ,
,
() (): ..., . ..
CLINICAL AND DEMOGRAPHIC ANALYSIS OF THE INCIDENCE OF
PSORIASIS IN KURSK AND KURK REGION
Azarenkova Y.A
Kursk State Medical University, Russia, Kursk
Medical Faculty, Department of Dermatovenerology
Scientific Adviser(s): Silina L.V., PhD
Keywords: clinical research, psoriasis
: ,
Abstract: The prevalence of psoriasis, a chronic and often severe course
of dermatosis, the highest incidence in young people, many unresolved
questions of etiology and pathogenesis, great material costs of
treatment and at the same time, the imperfection of therapies - all this
makes the problem of psoriasis include the most important goal of
healthsocial
health
issues.
,
,
,
,


- .

,
,
, .


.
,
,

 . , , , 2011 | 33

.

-

.
559 2009-2010.

,
. 302 (54 %),
- 29 (5,2 %), - 26 (4,7 %),
- 20 (3,6 %), - 18
( 3,2%), - 17 (3 %),
16 (2,9%), - 14 (2,5 %),
- 12 ( 2%),
- 10 ( 1,8 %),
- 9 ( 1,6%) , - 7 (1,3
%), , , - 6 (
1,1%), , 5 ( 0,9%),
, , , -
4 ( 0,7 %), , ,
, , - ,
4 ( 0,7 %).
71,4%,

, 28,6%.
393 (70,3 %),
166 (29,7%).
44,6 .,
(44,8 .) (42 . ).

7 .(I 0-20., II 21-30., III 31-40., IV 41-40., V-5160.,VI 61-70., VII 71-80., ). ,
I -43%.

11,5%.
,
:
, ,
, HLA--
: I ( 40
) II ( 40 ).
2009-2010 , I
74%, II - 26%.
,

(44,2%),
(18,2) (6,2%),
(5,7%), (25,7%).
-

.

.

.., .., .., ..
[email protected]
, ,
,
,
() (): ..., ... . .,
.., ..., . .
THE HYPERCROSSLINKED POLYSTYRENE OF THE SERIES STYROSORB IS
THE PERSPECTIVE HAEMSORBENTS FOR EXTRACORPOREAL
DETOXICATION IN TREATMENT OF SEPSIS AND SEPTIC SHOCK
Azarenkova Y.A, Doljikova Ju.I., Rybalka D.K., Anisimova N.Yu., Kiselevsky
M.V.

Dubna International University of Nature, Society, and Man, Dubna,

Russia
The Faculty of Natural and Engineering Sciences, Department of
Biophysics
Staff Researcher of Laboratory of Cell Immunity
Scientific Adviser(s): N.Yu. Anisimova, PhD, M.V. Kiselevsky, MD
Keywords: stirosorb, haemosorbent, hypercrosslinked polystyrene,
sepsis
: , ,
,
Abstract: We examined the ability of three nanoporous samples of
hypercrosslinked polystyrene of the series Styrosorb 516, 514, 414 to
eliminate the lipopolysaccharide itself, as well as a wide spectrum of
pro- and anti-inflammatory cytokines. As the result, the sorbents were
found to possess good characteristics of biocompatibility and sorbing
activity with regard to the endotoxin, as well as to molecules initiating
and mediating systemic inflammatory reaction in organism.


.


,
( )
(, , , ) ,

.
,
.


,

(3-30 )
( 1000 2/).
in vitro
( 414, 514, 516) :
, ()
.
, ,

, K.
pneumoniae (Sigma, USA) 60 .

: 1- (-1), 4 (-4),
(),
(), 8 (-8), 6 (-6), 10
(-10) (Sigma, USA).
( , ),
LAL- (Hycult biotechnology,
Netherlands).
2,
4 24 .

( 70%)
- (-1, -6, -8, ; ),
(-4, -10,)
(). ,
, 3
-4, -1, -10, , (35-91%)
-6 ( 10%).
( 50%)
,
514 414: 514
77 % , 414 79%
.

.
12%,
7%.

34 | III
414, ,
, .
,
,
514 414

,
,


.

.., .., ..
[email protected]
, ,
,
() (): ... ..
FEATURES OF HUMAN GINGIVAL BLOOD MICROCIRCULATION
ACCORDING TO LASER DOPPLER FLOUMETRY
Ibragim R.H., Ibragim K.R., Garibov A.G.
Peoples' Friendship University of Russia, Russia, Moscow
The Faculty of Medicine, Department of human anatomy
Scientific Adviser(s): Kozlov V.I., PhD
Keywords: microcirculation, laser doppler fluometry, gingiva, parodont
: ,
, ,
Abstract: The method of LDF-registration has allowed to reveal regional
features of a blood-groove in gingival microvessels and to obtain the
standard data on microcirculation in a human healthy gum.
, , ,

.


,

.
()

(35 )
.
-01 ( ) ,

-

.. . (2001).
(VLF = 1 ./ ), (LF
=4-10 ./), (HF = 15-20 ./)
(CF = 60-80 ./) .

.

,
.
, (ALF)
38.9% -,
HF- 29.06%, CF- 4.8%.
,
ALF -.
,

,
.
, -
-

.., .
[email protected]
...,
,

() (): ., .. .
MARKERS OF SEPSIS
Pluzhnikova N.A., Anisimova N. Yu
Oncology center of Russia, Russia, Moscow
Laboratory of cell immunity
Scientific Adviser(s): Kyselevskii M.V., PhD
Keywords: markers, sepsis,CD 95, 11b, 11c
: , , CD 95, 11b, 11c
Abstract: Sepsis is a serious constitutional inflammation state that is
defined by a very high mortality rate.
In our research we have discovered that the expression of membrane
markers CD11c, CD11b and CD95, observed on the circulating blood
leukocytes, in blood samples of patients with sepsis diagnosis compared
to samples of donors without septic processes
We think that simultaneous increase of CD11b and CD11c expression
levels and decrease of CD95-positive cell number can be used as a
biological markers of septic processes in patients blood.

. , -
,

.
-
-,
.
, , -
, /,

. ,

. ,
,
,
.
, ,

,

.

(n=21) -
(n=10),
(n=10).
CD95, CD11b, CD11c (Becton Dickinson,
USA).
, , ,

CD11c ( - CR4) (76%)
CD11b (80%),
(28% 30% ).

(>0,05) CD11b - 53,4%, CD11 54,2%.

 . , , , 2011 | 35
CD95 -
,
CD95+
(=0,03) - 19,5% 42,25% .


.
, ,
CD11b CD11c
CD95 ,

,
.

.., .., .., ..
[email protected]
..
, ,

.. -

() (): ..., ... . .,

.. ..., . .
THE INVESTIGATION OF NEUTROPHIL ACTIVITY SPECIFICS OF CANCER
PATIENTS WITH SEPSIS AFTER VARIOUS PHAGOCYTOSIS FACTORS
STIMULATION
Rybalka D.K., Doljikova Ju.I., Anisimova N.Yu., Kiselevsky M.V.
N. N. Blokhin Russian Cancer Research Center, Russia, Moscow
Moscow State Academy of Veterinary Medicine and Biotechnology
named after K.I. Skryabin
Faculty of Veterinary Biology
Laboratory of Cell Immunity
Scientific Adviser(s): N.Yu. Anisimova, PhD, M.V. Kiselevsky, MD
Keywords: neutrophils, phagocytosis, cancer patients, sepsis
: , , ,

Abstract: The comparison of phagocytic activity of neutrophils of cancer

patients with sepsis and patients without sepsis has been performed.
The cellular activity was estimated in vitro as an ability to consume latex
granules and different bacterial cultures. It has been established that
such indicators of neutrophil functional activity as phagocytic index and
phagocytic number results of cancer patients with sepsis were
significantly higher than those for control group.
, ,

.
,

(IL-8, TNF, IL-6,
IL-1),
.



, , .

-, ,
:
( ) (
). ,


.

.
(16)
(15),
. 30
.
, Saccharomyces
cerevisae, Bacillus subtilis, Bacillus liheniformis, Lactobacillus
acidophilus. , ,
40
37. , -
.
100 ,
() ,
,
()
/ .
.
,
,
: ()
3,3-2,7 , ,
() 2-3,2
.
, -8

.
,
(S. erevisae, L. cidophilus 2-10 )
.
,
( )
, (
)
.
,
. ,


,
,


.

.., ..
[email protected]
, ,
,
() (): , ..., ..
WEEKLY DYNAMICS OF STUDENT'S HEART RATE VARIABILITY
Tarbaeva ..,Safronova .Y
Peoples' Friendship University of Russia, Russia, Moscow
The Faculty of Medicine, Department of Human Anatomy
Scientific Adviser(s): Gurov O.A., PhD
Keywords: weekly dynamics, heart rate variability, students
: ,
,
Abstract: The aim of this paper is to study student's weekly dynamics of
heart rate variability. The study included 14 boys and girls aged 18 to 25
years. It was conducted using the method of Cardiointervalographic RM
Baevsky. The observations were made from November to December
every day (except Saturday and Sunday) at a state of rest in the sitting
position for 5 minutes. The findings suggest that the activity of the
mechanisms of autonomic nervous regulation of heart rate is high on
Monday and Tuesday; on Wednesday the role of central mechanisms of
regulation significantly increases, while on Thursday and, especially, on
Friday both mechanisms, autonomic and central, function in more tense
mode.

,

36 | III

.

,

-
(..

).
,
.

14
18 25 ( 18,60,4 ).
..
(, )
( ).
,
,
5 .
().
(),
(SDNN) (CV),
,
.

- ( (SI);
-
(IC).
().
( HF,
VLF LF)
(TP)
, %.
.
.

:
1193, - 1124
.. 682
752 .. .
SDNN CV
,
. SDNN
61,94,2, - 62,312,3, - 41,58,7,
- 58,65,6, - 51,73,8 . CV
8,10,5 5,81,2
- 7,60,6 7,20,4 %.

SI,

.
SI 144,245,5,
200,181,8 , 476,4146 ,
172,136,8, 199,745,2 ..
.
IC 3,40,5,
- 2,80,6, - 3,30,6, - 3,80,4, 4,50,6 ..

TP 59361184,
- 10797960,
- 1964668 2.
4296759, - 3382541 2.
,

( HF) 30,22,9%,
35,46, 24,83,2,
:
27,22,9, - 23,02,5%.
(VLF), ,
(16,62,2%), -
(23,73,5). 18,720,0 %. (LF)

49,72,4 58,32,3%
.
(),

,
: - 4,70,3, - 5,60,4, 3,80,6, - 5,20,3, - 5,40,3 ..
,
,

,
, , ,
,
.
,
;
; ,
.

GIST-
.., ..
[email protected]
, ,
,
() (): ... .., ...
..
THE DIAGNOSTIC COMPLICATIONS OF THE GIST
Eykhenvald L.A., Kolesnikova M.S.
Peoples' Friendship University of Russia, Russia, Moscow
The Faculty of Medicine, Department of hospital therapeutics
Scientific Adviser(s): Mazurchik N.V., PhD, Polikarpova T.S., PhD
Keywords: gastrointestinal stromal tumors (GIST), leiomyoma,
gastroectomy, immunohistochemistry analysis, protein CD117
:
(), , ,
, CD117,
Abstract: Incidence of gastrointestinal stromal tumors (GIST) is 10 to 20
cases per million in a year. The aim of our study was to analyse the
cause of complications after gastroectomy in a patient with leiomyoma
of stomach. Our data has provided the evidence that incomplete
diagnostics led to incorrect diagnosis and resulted in a progress of the
disease by dissemination of GIST. Immunohistochemistry analysis for
detection of specific protein CD117 and non-invasive methods of liver
examination can be recommended for all types of non-epithelial
gastrointestinal tumors to verify or exclude the GIST diagnosis.
(, gastrointestinal
stromal tumors, GIST) 10 - 20 1
. . 1%
- ()
80% .
:
- 60%, - 25%, - 5%,
- 5%, - 2%. , ,
,
. GIST-
.
:



GIST-.
: , ,
, ,
,
.
, 57 . 2005 .
. 2007 .
-
, - .
,
38,50.

 . , , , 2011 | 37
,
,

.
,

,

/
, .

GIST CD117, ,

GIST.
.
,

.
,

.


GIST,

,
- .

.., ..
[email protected]
, ,
,
() (): ... ..

THE DISTRIBUTION OF PERSONAL PATHOLOGY'S TYPES IN CASES OF

EATING DISORDERS
Averyanov G. N., Brukhin A.E.
Peoples's Friendship University of Russia, Russia, Moscow
The Faculty of Medicine, Department of psychiatry
Scientific Adviser(s): Ph. D. Brukhin A.E.
Keywords: anorexia nervosa, bulimia nervosa, personality disorders,
personality questionnaires
: , ,
,
Abstract: This work is connected with the Identification of types of
personality disorders and their distribution in patients with eating
disorders by personality questionnaires.

()
.
.,

,
.
,

,
,
. 25
(
- , 4 ) 19
( 5
4 -). ..

.
()

(-),

,
,

,
.
,
,
.

. ..
.., .
[email protected]
..

-
() (): ... ..
HEART RATE VARIABILITY OF FEMALE STUDENTS OF THE TSPU NAMED
AFTER L.N. TOLSTOY OF THE TULA REGION
Azbuka I.N., Arhipova O.G.
Tula State Pedagogical University named after L.N. Tolstoy
Department of biomedical sciences
Scientific Adviser(s): Berestenko E.D.
Keywords: Variability of heart, rhythm, of female students, Tula region,
research, ecological conditions, habitat.
: , , , ,
, , , , ,
.
Abstract. Tula region can be divided into two eco-geographical zones:
the north-western and south-east. The purpose of this study is to
examine the influence of environmental conditions on the functional
characteristics of the cardiovascular system.North-western region of the
most favorable in terms of environmental conditions, characterized by a
higher level of functioning of the cardiovascular system. More
pronounced activation of the central contour and enhancement of
sympathetic regulation during exercise were also observed in girls from
the north-west. Students living in ecozones "North", a more balanced
activity of the autonomic nervous system, stationary time series study.
Therefore, when considering the heart rate variability in young women
from different environmental stress areas of residence, we can conclude
that the regulation of the cardiovascular system is the highest voltage
from residents of the regional center and environmentally troubled
southeast region, while residents of environmentally friendly north-west
region noted minor stress adaptation mechanisms.

.
, ,
-, .
.

- .
-
: - -.

,
.


- .
:

.
. 110
1
17-19 .
3
- 32 , - 48
., - 30 .

,

38 | III
().
,

.
-1

.. (1996).
10 15
.
5 .
100
.
Microsoft Excel, STATISTICA-5.
. ,
, (As),
,
, . -
-

() (<0,05). (),

. (),

,
, . (),
-
, - .
(V),
- ,
, . ,
,
, - ,
,
- .


-. ,
,
,
. ,

,
, -

- ,
-

.

-
Nrf2

..1, .. 1, ..1, ..1,
.. 1, ..2, ..1
[email protected]
1
, 2
-
() (): ..
ROLE OF REDOX-DEPENDENT REGULATION OF TRANSCRIPTION
FACTOR Nrf-2 IN FORMATION OF DRUG RESISTANCE OF CANCER CELLS
Kalinina E.V. 1, Basharov M.M. 1, Chernov N.N. 1, Novichkova M.D. 1,
Nurmuradov N.K. 1, Saprin A.N. 2, Berezov T.T. 1
1
Peoples Friendship University of Russia, 2Center of Theoretical
Problems of Physics-Chemical Pharmacology, Russian Academy of
Sciences, Moscow
Scientific Adviser(s): Prof. Kalinina E. V.
Keywords: redox-dependent regulation, transcription factor Nrf2, genes
expression, drug resistance of cancer cells, doxorubicin, cellular
antioxidant defense.

: - ,
Nrf2, ,
, .
Abstract: Role of redox-dependent regulation of transcription factor
Nrf2 in formation of cancer cells resistance to chemotherapeutic drugs
was studied. It was found that development of adaptive antioxidant
response to pro-oxidant action of doxorubicin in resistant human
erythroleukemia K562/DOX cells, human breast adenocarcinoma MCF7DOX cells, human ovarian adenocarcinoma SKVLB cells depends on
cellular genesis and has different character of co-ordinate alterations of
genes expression of antioxidant enzymes and enzymes which control
intracellular glutathione level, levels of glutaredoxin- and thioredoxindependent systems, peroxiredoxins, redox-dependent isoforms of
glutathioneS-transferase which are very important for cellular
antioxidant defense. A relationship between formation of drug
resistance of cancer cells, a rise of adaptive antioxidant response and
redox-regulation of transcription factor Nrf2 level was established.
Nrf2
II ,
ARE,
Nrf2.
(DOX)
,.
, ,
-
Nrf2,


K562/DOX, MCF-7/DOX, SKVLB,
DOX, .
( ) ARE : Mn-SOD
(SOD2), (CAT), 1 (HO-1);
,
(GSH) de
novo (GSSG), H L
- (-GCSH, -GCSL), (-Gt), (GSR);
- 1 (TRX1),
1 (TRXRD1), 1 (PRDX1),
2 (PRDX2); -
S- GSTP1-1 (GSTP1), GSTA4-4 (GSTA4),

. -
Nrf2 -
, -1 NF-kB,
-
,
, DOX.

,

.

.., ., ..
[email protected]
, ,
,
() (): ..
STRUCTURE OF SPECIFIC DEFEAT OF RESPIRATORY WAYS AT A
TUBERCULOSIS
Burakova M.V., Mbenga M., Matrosov M.V.
Peoples' Friendship University of Russia, Russia, Moscow
The Faculty of Medicine, Department of tuberculosis
Scientific Adviser(s): Matrosov M.V.
Keywords: Tuberculosis, fibrobronchoscopy, tuberculosis of airways, tool
methods of research

 . , , , 2011 | 39
: , ,
,

Abstract: Tuberculosis is the leading cause of death among all infectious

diseases. One of the most frequent complications of tuberculosis specific lesion of airways. The main method of detection of this
complication is the fibrobronchoscopy (FBS). This method allows us not
only to detect tuberculous lesions of the respiratory system, but also to
detect non-specific pathology, to clarify the presence of bacteria, to
verify the diagnosis.
, 10
,
,

.
,
.
,
.
: ,
.

1326

7 . 01.04.10
30.11.10.
: ,

164 , 106
(64,6%) 58 (35,4%).

,
.

- : 63
32 , 60,1% .
: 37
11 (30,4%).
( 6 8 ) ( 4 2) 8,8%
3,7% .
,
73 (87,2%) 21
(12,8%),
6,7% (11 ), - 20,12% (33 ).
15,8%
26 . 18

.

,
(

), .


, . 24


.
:

.
,

, .
,

,
,

.

II
..
[email protected]
.. ,
,
,
() (): ... ..
DETECTION OF ANTIGEN-PRESENTING SPLEEN CELLS WITH MHC CLASS
II IN NORMAL AND EXPERIMENTALLY
Voronkova O.V.
Chuvash State University named I.N. Ulyanov, Russia, Cheboksary
The Faculty of Medicine, Department of medical biology
Scientific Adviser(s): Ph.D. Sergeeva V.E.
Keywords: MHC class II, macrophages, trace elements, calcium, spleen,
modulation of immunity
: II , , ,
, ,
Abstract: Due to a decrease of immunological reactivity in the general
population now increasingly used are immunomodulatory, vitamin and
trace element preparations. Effect of trace elements of calcium on
neurotransmitter software lymphoid organs and immune cells not
covered in the literature. And so the theoretical interest in studying the
biological responses of cells of the body before and after the 60-day
admission preparation of calcium in drinking water.

, , , ,
, ,
,

.

60-
.
II

.
.
32 (150-200 ).
2 :
1- (n=16),
.
2- (n=16) 60-
( )
200 /.


MHC-II ,
().
SigmaScan.
.
- ,
. ,
, , ,

II .

,
II .
( 14,6%) ,
( 10,1%),
.
151 , 146 ( 5
), .

( 11,5%),
( 12,9%).

40 | III
SigmaScan
.. .

- II - 0,56 .. (
0,09). ,

- 0,73
( . 0,05). t- (t=0,007),
.
II
,
. ,

,

. ,
() ,
.
,

,
, - .
,
.

..
[email protected]
. .. ,
,
,

() (): .., ..,
.*., ..
EFFECTS OF SYNTHETIC PLATELET-ACTIVATING FACTOR ANALOGUE ON
PLATELET AGGREGATION
Grinchenko M.I.
M.V. Lomonosov Moscow State University, Russia, Moscow
Faculty of Basic Medicine, Department of physiology and general
pathology
Scientific Adviser(s): Ph.D. Gavrilova S.A, Dugina T.S., Ph.D. Malekin S.I.*,
Ph.D. Koshelev V.B.
Keywords: platelet-activating factor, PAF analogue, platelet aggregation
: , ,

Abstract: New analogue of platelet activating factor (PAF) 1-hexadecyl-2alkylcarbamoyl-glycerol (HAG) has hypotensive effect in hypertensive
rats. We investigated its influence on human platelet aggregation
(aggregation analyzer BIOLA, Russia, model 220LA). PAF in 310-7
induced aggregates 11,000,71 aggregation units in plated-rich plasma
(PRP). Plasma light transmission increased in 30,28,28%. Aggregates
2,400,37 in PRP was induced by HAG in 310-7. Plasma light
transmission increased in 1,530,57%. So HAG has no significant effect
on human platelets aggregation.


(),
1--2--
(),

.
.
,

, .


(,

LA220),

, -,
.
-.
()
10 8001000 /.
.
() 310-5 310-7
12,420,56 11,000,71
,
51,377,03% 30,28,28%.
310-7
2,400,37 ,
1,530,57%.
,
.

(),
. ,
, .
1,980,76 ,
3,292,2%.
. ,
.

-
.., .., ..
[email protected]
, ,
,
() (): ... ..
THE EFFECT OF MODERATE EXERCISE ON CARDIO-VASCULAR SYSTEM
OF THE STUDENTS
Gurenko S.V., Rybalskaya V.F., Pyatakova A.V.
Peoples' Friendship University of Russia, Russia, Moscow
The Faculty of Medicine, Department of human anatomy
Scientific Adviser(s): Ph.D. Gurova.O.A.
Keywords: physical load, heart rate, students.
: , , .

Abstract: Sixteen medical students of Peoples Friendship University of

Russia in age from 18 to 26 years were examined in order to study the
cardiovascular system in students with moderate physical activity. Heart
rate variability and microcirculation in the skin of fourth finger were
recorded before and after physical load.
-
(20
) 16
18 26 ( 19,6),
8 8 .
.. (
) ()
-01 ( , ).
4
.

(), (SDNN)
(CV),
.

- ( , SI);
-
(IC).
().
( HF,
VLF LF)
(TP)

 . , , , 2011 | 41
, %.
,
.
: ()
; () -
. () ( %)

-: (VLF),
- ;
(LF),
(); (HF),

; (CF),
. VLF LF-
, HF CF
.
().

.
.

- (SI) 126,327,3 8919,1 .. (
29,6%) (IC) c 3,20,8 1,50,3 .. (
54,4%),
.
(TP)
20,1%.
( HF)
33,85,0% 48,35,2%.

(VLF) .
(LF) 26,7% .

5 .

(43,57,5%)
.
(22,63,3%), 2 .

( 10,5%),
25,3%.
,
. - ,

, , -,
.
VLF- (
51,8% 53,8%) HF ( 8,5% 6,6%),
,
,
. ,

,
5 .
,
.

.., .., .., ..,

.., .., .., ..,
..
[email protected]

, , ;
, , -;
, , -;

() (): .-. ,
. .
"LIPOPEROXIDATION - ANTIOXIDANT PROTECTION" SYSTEM IN
BURYAT
POPULATION
WOMEN
OF
INFERTILE
WITH
HYPERPROLACTINEMIA
Darenskaya M.A., Kolesnikova L.I., Labygina A.V., Grebenkina L.A.,
Dolgikh M.I., Shiphineeva T.I., Darzhaev Z.Yu.,
Tsyrenov T.B., Rinchindorzhieva M.P.
Russian Academy of Medical Sciences Siberian Branch Establishment of
RAMS Scientific Centre of the Problems of Family Health and Human
Reproduction, Russia, Irkutsk; GOOSE Republican Perinatal Center,
Russia, Ulan-Ude; GOOSE Republican Clinical Gynaecological Hospital,
Russia, Ulan-Ude.
Laboratory of Pathophysiology of reproduction at Scientific Centre of
the Problems of Family Health and Human Reproduction, SB RAMS;
Scientific Adviser(s): orrespondent member of Russian Academy of
Medical Science, professor Kolesnikova L. I.
Keywords: lipoperoxidation, antioxidants, infertility, hyperprolactinemia,
the population
: , , ,
,
Abstract: The parameters of lipid peroxidation - antioxidant protection
in 20 women with hyperprolactinemia Buryat population studied.
Established that in infertile patients is an increase of toxic TBA - active
products, while reducing of antioxidant defense index, superoxide
dismutase activity, an increase in the range of changes in non-enzymatic
component - retinol.

40%

.

().
.
: -
, ,
.
. 20
( 32,471,14 )
, .
20
( - 28,142,11 ).
-
.

.
Statistica 6.0.
.


- 2,45 (p=0,000),

.
.

1,51 (p=0,000)
. ,

-
1,870,07 .. 1,730,03 ..
(F-)
, -.

42 | III
(r=0,56 r=-0,61, ),
(r=0,62). ,
,

. , ,

,
.


.

-


.., .., ..
[email protected]

, ,

() (): ... .., ...
..
PITUITARY-GONADAL SYSTEM FEATURES IN WOMEN WITH VIRAL
HEPATITIS B AND C DEPENDING ON MENSTRUAL CYCLE CHARACTER
Didenko E.L., Fedorov B.A., Sholohov L.F.
Scientific Center of Family Health Problems and Human Reproduction,
Siberian Branch, Russian Academy of Medical Sciences, Russia, Irkutsk
The laboratory of physiology and pathology of the endocrine system
Scientific Adviser(s): Sholohov L.F., M.D. Fedorov B.A.
Keywords: hormones of pituitary-gonadal system; viral hepatitis B and C;
menstrual cycle
: - ;
B C;
Abstract. The presented results testify that functional state of pituitarygonadal unit of neuroendocrinal regulation of reproductive system in
women with viral hepatitis B and C interrelates with clinical course of
viral hepatitis, etiological factor, activity of hepatic process and
menstrual cycle character.
. -

.
,

B C
.
.
. 125
. 90
, B C.

:
1 48 ,
;
2 42
.

:
1 ,

;
1 ,
;
2
;
2 ,
;

35

.
,
,

,
,
17-OH-.
. , ,
,
,

.

.


.


. 2
, 1.
2
, 1 .
1 ,
.
1
.
-
1 1

1. 2 2
,

,
,
. 17-.
2. 2
, 2.
.

.
-
.

,
,
.

1.44
.., .., .., ..,
..
[email protected]
, ,
,
() (): ... ..
THE INFLUENCE OF DIODE LASER COAGULATOR WITH A WAVELENGTH
1.44 MICRONS ON BIOLOGICAL TISSUE
Kazakova K.A., Frolov M.A., Gonchar P.A., Mihailov V.A., Morozova N.S.
Peoples' Friendship University of Russia, Russia, Moscow
The Faculty of Medicine, Department of eye diseases
Scientific Adviser(s): Ph. D. Frolov M.A.
Keywords: laser, coagulation, cornea, biological tissue
: , , ,

Abstract. Lasers are widely used in medicine. But effects of some types
of laser radiation and possibilities of their application arent researched
completely. Department of eye diseases at Peoples' Friendship
University of Russia has been studying the influence of diode laser
coagulator with a wavelength 1.44 microns on cornea. For the first
experiments we have chosen native chicken protein as the example of

 . , , , 2011 | 43
biological tissue that is strongly refractive and not scattering laser lights.
We irradiated native chicken protein with diode laser coagulator from 2
mm over proteins surface and evaluated the sizes of denaturated
protein, which told us about penetration of this type of laser radiation.
The results of the study allow to conclude that this laser coagulator can
be applied on cornea. We plan to continue our researches on isolated
cornea and on animals cornea.
,

, .

.
1,44-1,56 0,3-0,7
,

, , .


,
.
:
1,44 .
.


1,44
.
.

.

.
:
35*24
, 1 .
2


.
,
.
.

-

. 0,15
0,11
0,5 0,4 .
0.0165 . 0,27
2,95
1,3 1,2 . 0,7965 .
: ,

,
.

- 0,520,6 ,
11,2 , - ,


.
.

.., .., .., ..
[email protected]

"

"
, ,

() (): . . ., . .

MORPHOLOGICAL FEATURES OF THYMUS' STRUCTURE OF IMMATURE

WHITE RATS AFTER CYCLOPHOSPHANUM APPLICATION
Kashchenko S.A., Zakharov A.A., Churilin O.A., Eryomin A.V.
State institution "Luhansk state medical university"
The faculty of Dentistry, histology, cytology and embryology department
Scientific Adviser(s): Ph.D., M.D. S.A. Kashchenko
Keywords: thymus, rats, cyclophosphanum
: , ,
Abstract.Changes in the thymus structure of immature rats after single
dose of cyclophosphanum (200 mgs/kg intramuscular) administration
were studied. The absolute and relative the masses of organ, width and
area of cortex and medulla of lobules, cortex-medulla index were
measured. The reliable differences of morphometric indexes were set,
that specifies on the active reaction of thymus on exogenous influence.

,

,

. ,

. 12
-.

(200 /). ,
0,9% NaCl.
30 90
.
, -
.
30

9,90% 3,00%
.
43,29% 18,87%.
-
50,30%. 90

.
, 200
/

(90 .)

.

..
[email protected]
, ,
,

() (): ..., ..

THE EVALUAITON OF EFFICIENCY OF APPLICATION OF PREPARATION

LONGIDAZA AFTER OPEN AND ENDOSKOPIC INTERVENTIONS ON
STRICTURES OF URINARY WAYS
Kiryukhina T.A.
Peoples' Friendship University of Russia, Russia, Moscow
The Faculty of Medicine, Department of urology and operation
nephrology
Scientific Adviser(s): Dr.E.A. Avdoshin V.P.

44 | III
Keywords: Longidaza, stricture, efficiency, treatmrnt, relapse,
preventive.
: , , , ,
, .
Abstract. The improvement of issues of treatment patints with strictures
of urinary ways and preventive maintenance of relapses by application
of preparation Longidaza.

.
, ,
, .
, .

,
.


.

;
;
;

, .
20
,
29 .
2008-2009 . 17
, 3 .
40 70 , 54,5 . ,
, 2
. 15 ,
,

.

()
,

,
,
,
.
,

.

: , ,
,
, ,
,
,
, ,
.
1500 3 , 15
. 2
.
. 5 ,
.
1,5

.
15 (100%)
, ,
14 (93,3%) ;

()

,
() ,
;
.
.
2
4 (80%) ; ,

3 (60%) , 1 (20%)

.
1
15 (100%) 1
. ,

, 15 (100%)
. , ,
.
.
1 4 (80%)
.

1 (20%) ,
3 (60%) .

1 (20%) ; 1
(20%) ; 3 (60%) . ,


.
.



.
,

.

.

,
, ,
.

-
,

.
.., .., ..
[email protected]
, ,

() (): ... ..
SPECTRUM OF ANTIBIOTIC RESISTANCE IN CONDITIONALLY
PATHOGENIC MICROORGANISMS PROVIDED FROM BIOTOPES OF
UROGENITAL SYSTEM OF PATIENTS IN KRASNODAR CITY
Kolmogorova S.V., Obukhova N.A., Skoblikow N.E.
Kuban State Medical University, Russia, Krasnodar
Department of biology
Scientific Adviser(s): Ph.D. Obukhova N.A.
Keywords: Antibiotics, antibiotic resistance, conditionally pathogenic
microflora
: , ,
-
Abstract. The goal was to study the spectrum of antibiotic resistance in
conditionally pathogenic microorganisms isolated from organs of the
urogenital system. Biomaterial was investigated on 119 patients, 96.64%
of which consisted of patients aged 15 to 55 years.
.

- ,
,
CityLab .
.
.

 . , , , 2011 | 45
Agilent Technologies 6850c MIDI
Sherlock
6.0.

Staphylococcaceae, Streptococcaceae,
Enterobacteriaceae,
Pseudomonadaceae

.,

Candida.


(Neisseria gonorrhoeae, Trichomonas vaginalis),
Gardnerella vaginalis, Mycoplasma hominis Ureaplasma urealyticum.

-
11 (, ,
,
,
,
,
, , , ,
).
. 119 ,
96,64% 15 55 .

(27,73%) 25 30 .

(66,55% 34,45% ).
,
: 63,03%;
21,85%, 6,72%; 5,04%;
3,36%. 197
- ( 1,66
). ,
: (26,67%),
(21,54%), (16,92%),
(13,33%), Candida (13,85%).
92,31%
.

:
Enterococcus faecalis (23,08%); Escherichia coli (11,79%);
Staphylococcus capitis (7,18%); Streptococcus bovis (5,64%);
Staphylococcus aureus (3,59%); Staphylococcus haemolyticus (3,59%);
Staphylococcus epidermidis (3,08%); Enterococcus cecorum (3,08%);
Enterobacter aerogenes (2,05%).
63,08% .
,
Enterococcus faecalis
21,39% , Enterobacter aerogenes 20,00% ,
Staphylococcus capitis 12,39% , Staphylococcus haemolyticus
8,89% , Escherichia coli 6,96% , Streptococcus bovis
6,12% .
:
(42,77% ), (22,22% ),
(22,17% ), (21,84% ).

(100,00%),
(98,43%),

(92,94%),

(91,43%),
(91,34%).
.

, ,
, ; ,
, , , .

. .
[email protected]

, .
() (): ... .., ...
..

UNIVERSAL SKELETAL MUSCULATURE BIOPOTENTIALS-CONTROLLED

SYSTEM FOR TECHNICAL DEVICES AND LIMB PROSTHETICS
BIOELECTRONIC CONTROL
Kravchenko Sergey Vladimirovich
Kuban State Medical University, Russia, Krasnodar
The Faculty of Medicine, Department of histology with embryology,
Department of general and clinical patophysiology.
Scientific Adviser(s): Candidate of Medical Science Turovaya A.Y.,
Candidate of Medical Science Evglevskiy A.A.
Keywords: prosthetics, artificial extremity, bioelectric control,
myoelectronic control, biocybernetic systems.
: , ,
, ,
.
Abstract. In this article described how to create and test the device,
which converts the electrical signals of declining muscle in to control
signals for different technical systems and manipulator claws electric
drive. This results can be used in hybrid biocybernetic systems, which
controlling live tissue's, transport and other technical systems driving,
rehabilitation patients with muscle diseases and prosthetics
constructions.
.
,
,

.
,
.
,

,
,


.


,
.
.
: ,


.
, ,
, ,
,
, ,
.
.

.
,
.

.

,
.

,
.

.
1-55.

.
.
:

46 | III

10 Olecranon
(Ulna),
.

2 . 2
:

.

:

,
,

.

,
, .
1-55.

.

,
,
,
.



.
,

,
,

.
.
,
,
,
.
,

.


.

.
,
.
-
, ,
.

. ,
,


.
.
,
QRS,
P T.

,
,
.
- ,
.
:

,
.

, ,
.

,

.

, .
(
) ,
.
,
.
, ,
.
:

-
,
,
.

,


.

,
.

,

.

( ,
, ),

,
.

..
[email protected]
, ,

() (): . . ., ..

LEVEL OF ARTERIAL PRESSURE AND POLYMORPHISM OF GENES OF

FACTORS NECROSIS OF THE TUMOUR AT PATIENTS OF HYPERTENSIVE
ILLNESS
Krivoshei I.V.
Belgorod State University, Russia, Belgorod

 . , , , 2011 | 47
The Faculty of Medicine, Chair of medical and biologic disciplines
Scientific Adviser(s): d. m. s., professor Churnosov M.I.
Keywords: Polymorphism of genes, factors necrosis of the tumour,
arterial pressure.
: , ,
.
Abstract. Analysis of genetic polymorphism of the TNF (-308G/A) and
TNFR2 (+1663A/G) was performed using the polymerase chain reaction.
During the study, an association of polymorphism of these genes with
the level of blood pressure in hypertensive patients.

-
.

.
, , 24,4%
. ,

.

.

.

(-308G/A TNF)
(+1663A/G TNFR2)
,
.
39 .


IQ5.
.
-308G/A TNF
,
GG
135 . . ( 130-140
. .), AG
140 . . ( 125 . .,
140 . .). GG
90
. . ( 80-90 . .),
AG 90 . .
( 80-90 . .).

GG 200 . . ( 180220 . .), AG
172,5 . . ( 165 . .,
202,5 . .). GG

110 . . ( 100-130 .
.), AG
105 . . ( 100 . .,
117,5 . .). ,


AG
, GG -308G/A TNF.

+1663A/G TNFR2 ,
AG
130 . . (
120-140 . .), AA
140 . . ( 130150 . .), GG 135
. . ( 130 . ., 140 .
.). AG
90 . .
( 80-90 . .),
AA 90 . . (
80-90 . .), GG
90 . . ( 80-90 .

.).
AG 180 . .
( 165-200 . .), AA
200 . . ( 170-250
. .), GG 200 . .
( 190-210 . .).

AG

100

.
.
( 100-130 . .),
AA 110 . .
( 110-120 . .),
GG 120 . . ( 110120 . .). ,

+1663A TNFR2
, +1663GG TNFR2.

.., .., ..
[email protected]
, ,
,

() (): ... ..
NEUROPHYSIOLOGICAL RESEARCH ADAPTIVE ORGANISM POSSIBILITIES
Kutenev A.V., Radysh B.B., Uvarova A.V.
Peoples' Friendship University of Russia, Russia, Moscow
The Faculty of improvement of professional skill of medical workers,
Department of gerontology
Scientific Adviser(s): Ph.D Radysh B.B.
Keywords: neurophysiology, adaptive
: ,
Abstract. Dynamic testing of arterial pressure, the
data at physical activitycan become an express method for revealing of
the latent infringements of adaptive processes and contingent
formation, for medical inspection and treatments.
, ,

,
.
,
- .

,


.
203 (127 76
) 18 25 , .
DM
2010 Iritech,
, .
:
-.


Statistica.

85 ,
36 ,
117 ,
69 ,
41
, 105
, 119 .
100+/- 25
.. 90+/- 23 .. .

48 | III
108+/-24
. .., 98+/-26 . ..
61+/-12 .
151+/-28 . 23 (14 9 )
49-58
, .

85+/-9 .

.

, ,
,

. ,
,

-
,

.


,
,

.
-

.
,

,

-
-
,
.

.., .., ..
[email protected]
, ,
,

() (): ... ..
RESEARCH OF ADAPTABLE POSSIBILITIES AT PATIENTS WITH
SEGMENTARY CARDIALGIA
Kutenev A.V., Radysh B.B., Fedorovskaya T.V.
Peoples' Friendship University of Russia, Russia, Moscow
The Faculty of improvement of professional skill of medical workers,
Department of gerontology
Scientific Adviser(s): Ph.D Radysh B.B.
Keywords: cardialgia, age, research
: , ,
Abstract. The prevailing part of the investigated has latent decrease
adaptable possibilities of different degree of expressiveness. There is a
various reaction to the physical activity, shown by normalisation of
indicators of independent nervous system, adaptable possibilities or
strengthening of a vegetative disbalance. On the basis of the received
results probably division of patients into groups of risk with the
subsequent working out of actions for treatment, correction and
preventive maintenance of neurologic complications of is degeneratedystrophic changes of a backbone.

80%
.


, ,
,
.

, ,
,

-
.
176 (101 75
) 28 45 .
:
, , ,
.
DM 2010 Iritech,

, . :

-.
, 27 (15,3%)

135-145 . .,

158 (89,7%)
,

.
11 (6,3%)
, .
23
(13,1%), 31 (17,6%).
48 (27,3%)

: ,
, . 64 (36,4%)

,
8 15
.
, ,

.

,

,

.

,

-
.

-

.., .., ..
[email protected]
, ,
,

() (): ... ..
THE AGE LOCAL STATIKO-DYNAMIC FRUSTRATION AT VERTEBRAL
CARDIALGIA
Kutenev A.V., Fomicheva E.V., Fedorovskaya T.V.
Peoples' Friendship University of Russia, Russia, Moscow
The Faculty of improvement of professional skill of medical workers,
Department of gerontology
Scientific Adviser(s): Ph.D Radysh B.B.
Keywords: Age, backbone, cardialgia
: , ,
Abstract. Neurologic research of not optimum statics and dynamics
specifies the reason of complications which influence quality of life of
older persons. Forecasting of decrease in adaptive possibilities at
persons of different age groups allows to change in due time the
treatment which is slowing down development of an osteoporosis,
osteoarthrosis and some clinical variants of an osteochondrosis.

 . , , , 2011 | 49

,
, ,
. , -

,
, , .


, - .



.
227 (129 98 ),

: ) (45-49 )- 84
(37 %), ) (61-74 ) 89 (39,2%), )
(75-90 ) 54 (23,7%).

,

.
.

- ( 85% )
( 15% )

. ,

,
- .
98%
, (58%),
(24%),

(18%),

(100%).

.

,

.
,

7,6 +\- 1,4, 5,4+\1,2, 3,5+\-1,1 , ,
.
,

,
.
,
,
.

7
..
[email protected]
, ,
,
() (): ..
AGE-RELATED CHANGES OF NEURONAL GROUPS OF THE FRONTAL
CORTEX OF THE BRAIN FROM BIRTH TO SEVEN YEARS
Likinova I.U.
Peoples' Friendship University of Russia, Russia, Moscow
The Faculty of Medicine, Department of human anatomy
Scientific Adviser(s): Professor Tsekhmistrenko T.A.

Keywords: neuronal groups, frontal cortex, neural grouping alopecia

type, pyramidal neurons, interneurons, intracortical fibers, integrative
function of the cortex, interneuronal communication
: , ,
, , ,

,

Abstract. Study of qualitative changes in the structural organization of
neuron groups of the frontal cortex in children from birth to 7 years
using a computer program "Image-Tools". Neonatal meet individual
groups such as alopecia. Up to 3 - 5 years increased the size of large
pyramidal neurons. By 5 - 7 years of growing fibrous components morphological substrate complexity of interneuronal relations in the
frontal cortex of human brain.
. ,

, (, 2003. .
124, 4. . 18-24).

(Cerebral Cortex 1993. Vol. 3. P. 399-411) -


.


III (III )
7 .
.
(22 )
7 .
10
44
() 8 ().

.

Image-Tools
.
.
. , III

.
4-5 8 12-15 44.
, ,
2-3 ,
( 44 -
IV).

,

.
,
2-3 8 10-12 44. 1 3-5

,
5
. 8 ,
, III ,

, 44
,
. ,
8, 44 5-7
,


.
. ,
,
,
(XXXIII International Congress of
Physiological Sciences. Abstracts. St.-Peterburg, 1997. P067.09),

50 | III

.., .., ..
[email protected]
,

THE STUDY OF THE CHEMICAL COMPOSTION OF LIPOPHILIC HERBAL
MEDICATIONS
Lobaeva T.A, Glushenko N.N, Gerashenko U.P
Peoples Friendship University of Russia
The Faculty of Medicine
Abstarct: Investigation of chemical composition (lipid, fatty acid and
vitamin) of lipophilic herbal medication (LHM) and biologically active
additives (BAA) and their comparison as index of activity. To find out the
chemical composition of LH and BAA, the following tests were
performed: determination of the presence of basic biologically active
compounds, physical and physiochemical chemical experiments: ThinFilm Chromatography (TFC) of neutral lipids, Gas-Liquid chromatography
(GLC) of fatty acids, spectrum analysis of carotinoid isomers with a range
of 300-500 nm and High Performance Liquid Chromatography (HPLC) of
tocopherol isomers. The amount of carotinoid, flavonoid and glycerine
was measured using different spectrometry analyzes. By applying
Emery-Engels method and HPLC, the tocopherol content was evaluated.
Neutral lipid content of extract LHM differs from the non-extract type.
Sustentative evidence is provided by the chemical analysis of neutral
lipids, content of saturated and non-saturated fatty acids, nonsaturation index and the amount of retinol derivatives, tocopherols,
flavonoids and glycerine. Further, the activity of LH and BAA can be
directly affected.
(,
)
() (),

.
.
,
,
- (
, ,
300-500 ,
).
,
.
- .

.
.
( , ,
-, )
, 96-98 %,
- 2-4 %
.
: , 6182 % , ,
, .


.

,
,
,
.
. ,

.

.
83 % ( ) 92 % (
) .

(,
,
,
,
),
,

( )
(, ), ,
, .
,
:
;
-, ; 40: , , .


( 40-). ,
-
,

( 62 %).
(,
) ,

-, , ,
.
. ,

,
,
,
, , ,

.

.., .., .., ..,
.., .., ..,
.., .., ..
[email protected]
,

() (): ... ..
ASSESSMENT OF LYMPHOCYTE IMMUNOREACTIVITY IN PERIPHERAL
BLOOD OF ACUTE TICK-BORN ENCEPHALITIS PATIENTS USING BY
CYTOGENETIC TECHNIQUE
Lubsanova L.B., Semenov A.G., Telbekova A.A.,
Zhurov I.A.,
Fasgetdinova A.N., Bitmukametova Yu. V., Kuzmina N.A., Nebaeva E. A.,
Onuchak N.P., Stepanova M.I.
Siberian State Medical University, Russia , Tomsk
Faculty of Pediatrics, Department of infectious diseases and
epidemiology
Scientific Adviser(s): M.D. Ilyinskikh E.N.
Keywords: chromosomal aberrations, acrocentic chromosomal
associations, lymphocyte proliferative response, tick-born encephalitis

, ,

Abstract. Mitogen-induced proliferative response and chromosomal
aberrations in peripheral blood lymphocytes of acute tick-born
encephalitis patients were determined. It was found that the patients
groups have significantly higher frequencies of cytogenetically aberrated
blood lymphocytes as well as lower levels of cells with nonassociation

 . , , , 2011 | 51
of acrocentic chromosomes compared to the control group, which
indicates that there are depress in proliferative response of blood T
lymphocytes in the patients.
()
,


.
,
, ,
,

in vitro.

.

,
,

.



.
:


.
:
10
. 7
, ,

.

,
52 ,
.
100 .

,
.


, ,
.

, .

Excel t-
.
:

,
(P<0,01),

(P<0,05). ,


,
.


, ,
,

-

(P<0,01).


(r= -0,72; P<0,01).

ADH1B

., .., .., .
[email protected]
, ,
,
() (): ... ..
POLYMORPHISM OF THE GENE FOR ALCOHOL DEHYDROGENASE
ADH1B POPULATIONS IN THE MIDDLE EAST AND NORTH AFRICA
Mbenga M., Burakova M.V., Koshehkin V.A., Kim A.
Peoples' Friendship University of Russia, Russia, Moscow
The Faculty of Medicine, Department of tuberculosis
Scientific Adviser(s): Ph.D. Koshehkin V.A.
Keywords: Alcohol dehydrogenase, polymorphism, metabolism,
tuberculosis, antituberculous chemotherapy, genotyping.

:
,
,
, , ,

Abstract. ADN enzyme controls the first stage of oxidation ethanol in the
human body. The gene encoding this enzyme is distributed unequally in
populations with a greater frequency of occurrence in populations of
South-East Asia. This enzyme system also plays a role in the disposal of
toxic metabolites of TB drugs.

, ADH1B.
ADH1B 4 ADH,

. - 80%

ADH1B*48His
( G => A,
Arg48His, ADH2*1 ADH2*2).
ADH1B*48His
,
.
,
.

,
.
450 ,
,

450
, (, ,
, ).




, ,

,

.
-
,
, , ,

,
,
450

(- ,
.).
1
. ADH1B*48His
70-80%,
ADH1B*48His 5-8%.
0-3%
30% .

.
.

52 | III
-
9
.
.
QIAamp DNA Blood Mini
Kit QIAGEN ().
.
ADH1B*48His

(31+13%). , , ,
.
( 4 23 )


.

ADH1B*48His
,
.

., .
[email protected]
, ,
,

() (): .. ..
CLINICAL ISSUES OF REFEEDING SYNDROME IN EATING DISORDERS
THERAPY LITERATURE REVIEW OVER THE LAST DECADE.
Melamud A.A, Chepelev A.V.
Peoples' Friendship University of Russia, Russia, Moscow
The Faculty of Medicine, Department of psychiatry and medical
psychology
Scientific Adviser(s): Ph.D Bruhin A.E.
Keywords: refeeding syndrome, eating disorders, nutrition rehabilitation
: , ,
, ,

Abstract. Refeeding syndrome is life threatening, poorly diagnosed, yet

preventable condition. It occurs during nutritional rehabilitation after
period of starvation or malnutrition. Refeeding syndrome in eating
disorders therapy is caused by rapid refeeding of underweight and
malnourished patients. This review summerises pubmed search for
refeeding syndrome eating disorders over the last decade, disscuses
this syndrome clinical aspects in eating disorders therapy and outlines
the importance of refeeding syndrome awareness and prevention in
nutritional therapy of eating disorsers.
: ,

, ,

:

, pubmed
refeeding syndrome eating disorders
2001- .
:

( ),
,
.
7 .
10 46
19-22 .

.
, ,
.

: , ,
, , .
- ,

, , , , ,
.

,
,
,

. Sato M, Kitamura N
(2004)
,
,
.
:
10
: ,
, , .
.
,

24-42 ,
-.

,
,

.

.., .., .., ..,

..
[email protected]
.
.., ,
-

() (): ..., ..

COMPUTER COHERENT PHASE MICROSCOPY AS THE REAL-TIME

METHOD OF CELLULAR DIAGNOSTICS
Metelin V.B., Artemov D.V.,Kekalo A.I., Rustembekova S.A., Ivanjuta I.V.
N.I.Pirogov Russian State Medical University, Russia, Moscow
Scientific clinical center of gerontology, Department of computer
cytomorphometry
Scientific Adviser(s): Ph.D., professor Vasilenko I.A.
Keywords: Coherent phase microscopy, computer morphometry, blood
cells
: ,
,
Abstract.The possibility of computer coherent phase microscopy (CPM)
like as noninvasive diagnostic method for evaluation of
morphofunctional status of living cells which provide the real-time
information about of activity of intracellular processes in terms of the
local optical distance difference variations are considered. The using of
CPM allows to achieve the new diagnostic information about the cell
morphofunctional status, opens the additional vistas for analyzing the
heterogeneity of circulating cell populations.

, ,
.

,

,

 . , , , 2011 | 53

-
.
-
,
-
.

,
, ,
.
,

-
,
: ,
, ,
(
) .


()
. ,
, 200 .

. 5 50
,

1024
.

hmin = 0,5 ,
1 ( 1
).

, , ,
, .

,

I, II III . I ( TLUCK)
-
(, 3D-, ,
). II ( MORPH)
(
Dmax, Per, Height, Area,
Vol);
( );
(
). III (
StatM)
(Dmax, Per, Height, Area, Vol), .
, -

,

.

- ( ,
, .) ,
.
, ,

.
,

, .

,
.

CANDIDA
.., ..
[email protected]
, ,
,
() (): ... - ..,
... ..
SENSITIVITY TO ANTIMYCOTIC PREPORATIONS OF THE CLINICAL
INSULATOR OF CANDIDA MUSHROOMS
Nikitin R.V., Idrisov M.F.
Ulyanovsk State University, Russia, Ulyanovsk
The Faculty of Medicine, Department of microbiology
Scientific Adviser(s): Ph.D. Potaturkina-Nesterova N.I., Ph.D. Nemova I.S.

Keywords: Candidiasis, antimycotics, sensitivity, Candida mushrooms,

etiological factor, specific range
: , , ,
Candida, ,
Abstract. The work covers the issue of species structure of pathogens of
oral candidiasis, as well as studied the spectrum of the most effective
antimycotic preporations.
.

.
:

,
, Candida.
: 70
, 31 39 .
,

.
- ,
.
.

(, ,
, , , )
- .
: 30
(40,8%) C. albicans,
21 (30,0%) . krusei, 15 (21,4%) C.
pseudotropicalis, 3 (4,3%) C. tropicalis 1 (1,4%) C.
arapsilosis.

Candida :
97,1%, 95,7%,
70,0%, 24,3%, 10,0%
4,3% .
Candida

, C. albicans
(100%) (90,0%), . krusei (100%), C.
pseudotropicalis (93,3%), C. tropicalis
(100%) C. arapsilosis (100%)
(100%).
: 1)
andida C. albicans,
C. krusei, C. pseudotropicalis, C. tropicalis C. parapsilosis.
C. albicans, C. krusei C. pseudotropicalis.
2) Candida,
,

.
.

54 | III
.., .., ..
[email protected]

, ,
,
() (): ... ..
LOCATION OF THE PYRAMIDS TEMPORAL BONES AND SOME
PARAMETERS OF THE SKULL
Ogienko A.V., Mironova D.I., Shimko A.S.
Kubanskiy State Medical University Federal Agency on Public Health and
Social Development, Russia, Krasnodar
Medical faculty, Department of normal anatomy
Scientific Adviser(s): k.b.n. Bahareva N.S.
Keywords: Temporal, bones, slopes, skull, dimple, index
: , , , , ,
Abstract. On the grounds of called on studies and got result possible to
do the following findings:
- sizes of the back cranial dimple to straight proportional corner of the
slope of the pyramids temporal bones
- is defined leftside asymmetry of this corner
- inverse intercoupling with long skull.


.
21 ,
.
,
MB-Ruler
Microsoft Excel.

:

( MB-Ruler);
;
.
:

=0,034671039;

(r=-0,280783821),
.. (r=-0,270,09);

(r=0,403822702);

(r=0,37105);

(r=0,364455);

(r=0,37105);

(r=0,364455);
,
,

.

.

, , ,

. ., .., ..
[email protected]
, ,
,

() (): ... ..

MONITORING OF ADVERSE EFFECTS OF CHEMOTHERAPY FOR

ONCOLOGICAL DESEASE
Orudzhev F.K., Gulinov K.A., Oksanchuk E.A.
Peoples' Friendship University of Russia, Russia, Moscow
The Faculty of Medicine, Department of basic and clinical pharmacology
Scientific Adviser(s): Ph.D. Zhuravlev R.I.
Keywords: adverse drug reactions, bevacizumab, capecitabine,
carboplatin, oxaliplatin, etoposide

,
, , , ,

Abstract. The objective of the experiment was to investigate the adverse

effects, that are related with the use of oncological drugs in both
hospital and out-patient therapy and find out some differences in cases
of ADR between men and women. 125 cases regarding the adverse
effects due to the use of certain oncological drugs, such as bevacizumab,
capecitabine, carboplatin, oxaliplatin, etoposide were analized. Some
regularities were observed: the using of etoposide often causes the
affection of cardiovascular and hemopoetic systems. Besides, combined
therapy by several medicines may result to summation of their adverse
drug reactions.
.
2008 7,6
( 13% ).
,

.
: ,
,
.
:

2006-2010.


.

.
.
:

.
:
Medstatistika.
: 125
2006-2010 .

,

,
-
, ,
, (,
.).
,
:

2/3 (40% 60% ). ,

16% , 84%.
,

,
.
: 28%

(, ,
), 19% ,
. , , 13%
,

 . , , , 2011 | 55
, , ,
. .
, 240
160 , . 62
IIIB ,
, ,
.

, .
.
.
,

,
.
,
.

,
.

..
[email protected]
, ,

() (): ... ..
THE RISK OF STIGMATIZATION OF PSYCHIATRIC PATIENTS BY FUTURE
DOCTORS AND SOME APPROACHES TO THE DEVELOPMENT OF
MEASURES TO PREVENT IT
Pozhogina E.A.
Russian State Medical University, Russia, Moscow
The faculty of pediatric, Department of Psychiatry and medical
psychology society
Scientific Adviser(s): Ph.D. Pankova O.F.

,

, ,
.
, ,
, , .


.

.

,
,
.

.., ..
[email protected]
, ,
,

() (): ... ..
THE MEANING OF GENETIC MARKERS IN PROSTATE DISEASES
Pulbere S.A.,Loktev A.V.
Peoples' Friendship University of Russia,
Russia, Moscow
The Faculty of Medicine, Department of Urology and Operation
Nefrology
Scientific Adviser(s): Ph.D. Avdoshin V.P.
Keywords: Growth factors, prostatic diseases, expression, Genetic
Markers
: , , , ,

Keywords: Negative attitude towards people suffering from psychiatric

disorders; discrimination; stimulus to hide psychiatric disorders.
: ,
; ;
.

Abstract. The study is directed to one of actual urologic problems - to

improve diagnostic of malignant prostatic neoplasms. Cells have been
obtained during biopsy in patients with prostatic diseases (such as
chronic prostatitis (CP), benign prostatic hyperplasia (BPH), prostatic
intraepithelial neoplasia of high degree (PIN 2 3) and prostatic cancer
(PC), and study of level expression of mRNA of vessels endothelial
growth factors and it`s receptors with the cells was performed.

,
,
.
,
, . ,

,
-

(59 25 ).

. , ,
-

,
. 84
:
-
38. (45,2%)
- 24 (28,5%);
- ,
15 (17,8%);
- ,
(
) 18 (21,4%);
- 40 (47,6%);
- ,
44 (52,4%);
- ,
33 (39,2%).

(IGF,EGF,TGF,PDGF .)
(). ,
-
(MMP), , MMP-7 (),
,
. ,

.
TRF1,

.

VEGF,TRF1, MMP-7 ,

(), ,
()
KDR/FLT1,FLT-1/VEGF TRF1/MMP-7.
. 77
49 ,
29,

. 66,3 .

5 : (n=3), (n=15), ()(n=4),
( 2-3)(n=3)

56 | III
: -, -
(, , ) (n=24).
.
TRF1 MMP-7.


, ,
.
- -
TRF1 -7 (0,05).
TRF1
-
(1,07/0,39)

-
(1,02/0,39)(0,05).

-7
-(1,45/0,53) -(0,64/0,53)(0,05).
,
-7
- (1,45/0,53) -
(0,64/0,53) (0,05). , , , ,
TRF1/-7.
(0,05)
- (0,76/1,05). - (0,76/1,46) (1,05/1,46) TRF1/ MMP-7.
KDR/FLT-1
23 , , 7 ,
2 , .
FLT-1/VEGF
50 , 4 ,
.
, TRF1,
MMP-7, TRF1/MMP-7


,
, ,
.

.., . .
[email protected]

,
() (): ... ..
STUDY THE INFLUENCE OF INFUSIONS OF PLANTS KARELIN CASPIAN
ON BLOOD SUGAR LEVELS
R.S.Samedinov, H.U.Aliev
The Tashkent Pharmaceutical Institute
Pharmacy, Clinical Pharmacy
Scientific Adviser(s): Ph.D.Prof. Aliev.H.U.
Keywords: Hypoglycemia, hyperglycemia
: ,
Abstract. Experiments have shown that infusion of study in the above
doses, has a pronounced hypoglycemic effect. Consequently, the
studied infusion in the studied doses, expressed lowers blood sugar
levels at 33.56% and 37.37%. That results are the basis for further indepth study of general and specific pharmacologic hypoglycemic effect
of the drug.
, ,
. ,
,
,

.
,

.
, .

,
, .
. 30
, 167-223.
40%
4,5/.
40% ,
(Karelinia caspica (Pall) less)
., 2,5-5 / 30
. 40%
. 60
.
. ,
,
. ,
60- , 40%
46,5 %,
( 6,10 0,77 /
8,940,44/), ,
2,5 / 5 /, 60
40% , 5,92 0,52
/ 5,6 0,46 / . ,

33,56 % 37,37 % ,
.
. , ,

, 40%
. ,



.

. . .
.., ..
[email protected]
.
. .
, .
-
() (): ... ..
THE HEALTH STATUS OF GIRLS TULA STATE PEDAGOGICAL UNIVERSITY.
LEO TOLSTOY
Safonova M.V., Shinkar T.S.
Tula State Pedagogical University. Leo Tolstoy, Tula, Russia
Faculty of Science, Physical Education and Tourism. The department of
biomedical sciences
Scientific Adviser(s): PhD Berestenko E.D.
Keywords: Health indicators, questionnaires, development
: , , ,

.

.
.
: ,
.

.
17-19
-
,
.
100

. .. 17-19 .
,
3 : - 40

 . , , , 2011 | 57
, -30, - 30.

.
, .

.
, ,
-
.
.
,
. ., - -

25 %, 19 %
24 %
.
, , ,
,
, -,
, -
,
- .


.

..
[email protected]
,

- ,

() (): ... ..
ACTIVITY OF NUCLEOLAR ORGANIZER REGIONS, BLAST CELL
TRANSFORMATION AND CYTOKINES PRODUCTION OF PERIPHERAL
BLOOD LYMPHOCYTES IN ACUTE LYME BORRELIOSIS PATIENTS
Semenov A. G.
Siberian State Medical University, Russia , Tomsk
Biomedical Faculty, Department of microbiology and virusology
Scientific Adviser(s): M.D. Ilyinskikh E.N.
Keywords: lymphocyte cultures, blast cell transformation, nucleolar
organizer regions, lyme borreliosis
: , ,
,

Abstract. It was found that phytohemagglutinin-stimulated lymphocyte

cultures of the acute lyme borreliosis patients groups have significantly
higher levels of interleukin 4 production in supernatants, lower
frequency of blast-transformated cells as well as lower area of
argyrophilic nucleolar organizer regions compared to the cultures of a
control group, which indicates that there are depression in T
lymphocytes proliferative response in the patients.

- ,
,

.
,

( D- G-)
.

,
,
.

. ,

. ,
,
.

-4 (-4) - (-)

.
,


(Howell, Black, 1980).
ImageJ


,
,
.
,
(n=28),
,
,
-4 ,
(P<0,01).
,
,
-4,

(P<0,05),
.
,

. ,

-
.

.
..
[email protected]
, ,
,

() (): ... ..
HISTORY OF CREATION AND PRINCIPLES OF WORK OF SERVICE OF THE
FAST PSYCHIATRIC HELP IN MOSCOW
Solodkov P.V.
Peoples Friendship University of Russia, Russia, Moscow
The Faculty of Medicine, Department of psychiatry and medical
psychology
Scientific Adviser(s): Ph.D. Artemeva M.S.
Keywords: Psychiatry, first aid, principles of work.
: , , .

Abstract. The fast psychiatric help is created in 1927. As the beginning

opening psychiatric crew at station of first aid has served. Today the
department of the psychiatric help is created at station of first aid into
which the operations section and 23 crews enters. The primary goals the
department of the psychiatric help-duly revealing and prevention of
complications of mental diseases."

-
1927 . : -,
.

58 | III
, .

. ..
, :
, , , 23
, :
( 63/),
( 65/),
( 79/).
.



, .

- ,

.

. ,
, ,
63/; - 79/;
65/.
, -
: 65/,
()
.
65000 ,
: 23%
,
- .
- ,
. 16%
63/,


. 65/
( 31%
) ,
. 30%
79/,
,
,
, -.
50%
.

,
3, 4;
,
, 1, 20, 67, 20. ,

,
,

. 17
19 -.
,

,

, ;

,
:

.

..
[email protected]

. .. , ,
.
,
() (): ... ..
DISORDERS OF LIPID PEROXIDATION OF TISSUE STRUCTURES OF THE
BRAIN IN ENDOGENOUS INTOXICATION
Spirina M.A.
Mordovian State University, Russia, Saransk
The Institute of Medicine, Department of Neurology & Psychiatry
Scientific Adviser(s): Ph.D. Merkushkina I.V.
Keywords: endotoxicosis, peritonitis, brain, lipid metabolism disorders
: , , ,

Abstract. The experiment on the model of acute peritonitis shows that
functional-metabolic defects in brain are connected with large
modifications of lipid composition of their cellular structures which
correlate with endotoxicosis apparency.
:
.

20 ,

..
,
2,
.
: ,

,

. ( = 254 = 280
) 77,04136,54 54,66
137,05% (<0,05) .

18,9630,73, 34,1152,60
21,2150,00% (<0,05).
. ,

.

28,14188,33 21,35
72,99% (<0,05).
,

.

.
:
,

, .

.., ..
[email protected]
, ,
,
: , ... . .
LASER SCANNING RETINOTOMOGRAPHY AS A METHOD FOR
MONITORING OF PATIENTS WITH GLAUCOMATOUS OPTIC
NEUROPATHY
Frolov A.M., Morozova N.S.
Peoples, Friendship University of Russia, Russia, Moscow
The Faculty of Medicine, Department of ophthalmology PFUR.
Scientific Adviser: professor, d.m.s M. A. Frolov

 . , , , 2011 | 59
Keywords:
glaucoma,
glaucomatous
optic
neuropathy,
retinotomography.
: , ,

Abstract: HRT III is high detective in changes of optic disk, macula and all
central zone of retina. HRT III is very effective in diagnostic early
glaucomatous changes of optic nerve. Special program let you see
normal, boarded or pathological changes of optic nerve. Also it is very
effective in diagnostic of early macula degeneration
.
,
,
.
HRTIII (Heidelberg Engineering,
).
,
. HRTIII

.

.
:

(CDP choline).
:
HRT III 18

(CDP choline).
500 / 10 .

Mann-Whithney (
p<0,05).
:

: ,
, ,
,
. ,


,
.
.
.

,
( RNFL). ,
RNFL
0,180,03,
0,190,01.
: HRTIII

,

.

.

(CDP CHOLINE)

.., ..
[email protected]
, ,

: , ... . .
COMPARATIVE EVALUATION OF DIFFERENT DOSES ITIOLIN (CDP CHOLINE) IN THE TREATMENT OF PATIENTS WITH PRIMARY OPENANGLE GLAUCOMA
Frolov A.M., Morozova N.S.

Peoples, Friendship University of Russia, Russia, Moscow

The Faculty of Medicine,Department of ophthalmology PFUR.
Scientific Adviser: professor, d.m.s M. A. Frolov
Keywords: citicoline, CDP choline, glaucoma, glaucomatous optic
neuropathy, retinotomography.
: , CDP - choline, ,
,
Abstract: t the Clinical Hospital 12 of Moscow 36 patients (58 eyes)
with primary open-angle glaucoma (POAG) stage II-III with normalized
intraocular pressure were treated by citicoline in a different doses
during 10 days. We have evaluated the effect of citicoline (CDP
choline) on visual function, morphometric characteristic of retina
tomography, characterizing the optic disk, and perimetric indexes of the
static automatic perimetry; we have compared the dynamic of
estimated characteristic with those before treatment.
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60 | III
ANALYSIS OF THE EFFICACY OF COMBINED TREATMENT SENILE
MACULAR DEGENERATION
Frolov M.A, Aldieva, EM
Peoples' Friendship University of Russia, Russia, Moscow
The Faculty of Medicine, Department of ophthalmology
Scientific Adviser(s): Ph.D.Frolov M.A
Keywords: Analysis of the efficacy of combined treatment senile macular
degeneration.
:
.
Abstract. Comprehensive treatment of AMD including peptide
bioregulator ""retinalamine"" in combination with hyperbaric oxygen
therapy achieves the best results compared with conventional therapy.
The research points to the efficacy of this treatment and the desirability
of further study.
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CORRECTION OF HYPOXIC AND COAGULATION DISORDERS IN THE
TREATMENT OF AGE RELATED MACULAR DEGENERATION
Frolov.M.A., Gonchar. P.A. , Lantukh.E.P.
Peoples' Friendship University of Russia, Russia, Moscow
The Faculty of Medicine, Department of eye diseases
Scientific Adviser(s): prof.Gonchar. P.A.
Keywords: Correction , hypoxic , coagulation, disorder, treatment ,age
related,macular ,degeneration.
: , ,
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, , , , .
Abstract. Correction of hypoxic and coagulation disorders in the
treatment of age related macular degeneration. We have developed a
method of treating age related macular degeneration with inhalations of
heparin and oxygen therapy. Using this method we have treated 14
patients (23 eyes). 9 patients with early stage of age related macular
degeneration and 5 patients with advanced disease. Positive effect was
achieved in all cases without any exception. The average increasing in
visual acuity in the first group was 0.2, and in the second 0.1. The followup period by this moment is about 2 months. During this time the
results are stable. Using of this method is pathogenetically
substantiated, and the availability of special equipment determines its
accessibility and ease of application. Removal of hypoxia and circulatory
disorders helps to stabilize the process, to increase broad visual field
and visual acuity and also effects beneficially on a somatic status of the
patient. Application of this method will allow to treat effectively patients
with age related macular in the conditions of polyclinic.
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 . , , , 2011 | 61
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THE COMPARISONS OF VISUAL ACUITY IN STUDENTS OF VARIOUS
FACULTIES OF THE PEOPLES' FRIENDSHIP UNIVERSITY OF RUSSIA
Tsibikova M.V., Grigoryeva M.D.
Peoples' Friendship University of Russia, Russia, Moscow
The Faculty of Medicine, Department of ophthalmology
Scientific Adviser(s): Ph.D. Frolov M.A.
Keywords: myopia, nearsightedness, blurred vision
: , ,
Abstract. Objective: To identify faculty and students who suffer from
myopia more frequently than in other departments of the Peoples'
Friendship University of Russia. Materials and methods: The work was
done on the basis of a city polyclinic 25 members of People's
Friendship University Students' Scientific Circle. Subjects: register of
patients. Results: of the 11 teams most revealing were the results in
groups of four faculties - Philology, Faculty of Humanities and social
sciences, economic and legal. 1. In the group of philology percentage of
students who are suffering from myopia, was 12, 333%. The share of
low, medium and high degrees of myopia amounted to 64.215%,
28.431% and 7.353%. 2. Under the Faculty of Humanities and Social
Sciences, the percentage of students who are suffering from myopia,
was 9.370%. The share of low, medium and high degrees of myopia
amounted to 73.118%, 23.118% and 3.763%. 3. In the group of
economic faculty of the percentage of students who are suffering from
myopia, was 8.963%. The share of low, medium and high degrees of
myopia amounted to 68.504%, 25.197% and 6.299%. 4. Under the Law
Faculty the percentage of students who are suffering from myopia, was
8.415%. The share of low, medium and high degrees of myopia was
respectively 80% and 13.684% and 6.316%. 5. The percentage of low,
medium and high degrees of myopia in all faculties in average,
respectively 68.959% 22.608% and 8.433%. Conclusions: 1. An active
visual workload has a significant influence on the development of
myopia among students Peoples' Friendship University, where
manifestations are closely connected with the faculty, which is trained.
2. The study found the highest percentage of different degrees of
myopia among students of the Philological Faculty. In addition, the
Faculty of Philology is leading to disease severity, as evidenced by the
presence of larger percentage of episodes of high myopia. 3. The
structure of the disease predominate weak degree of myopia, which
indicates a low level of the progression of this disease on the faculties of
the Peoples' Friendship University of Russia.

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 . , , , 2011 | 63
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NEURAL NETWORK SYSTEM OF DIFFERENTIAL DIAGNOSTIC OF
CARDIOVASCULAR DISEASES
Yasnitsky L.N., Dumler A.A., Poleshuk A.N., Mamatova A.Y., Bogdanov
K.V., Cherepanov F.M.
Perm State Medical Academy named E.A. Wagner, Russia, Perm,
Perm State Pedagogical University, Russia, Perm,
Department of Propaedeutics Internal Medicine,
Department of Applied Mathematics and Computer Science
Scientific Adviser(s): MD A.A. Dumler, Ph.D. Yasnitsky L.N.
Keywords: cardiology, diagnosis, mathematical model, neural network.
: , , ,
.
Abstract: Computer diagnostic system was developed for detection of
most widespread cardiological diseases. At the basis of the diagnostic
system there are neural networks trained with examples of work by
highly skilled medical experts. It can diagnose 8 diseases using 51 input
units that describe the patient and his symptoms. The diagnostic system
can be useful as a decision support system for specialists, for example,
working in countryside, as well as for mass prechecks of populations
state of health.
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THE COMMERCIALIZATION OF THE SCIENCE RESERACH RESULTS LIKE
INTELLECTUAL PROPERTY
Gordon K.B.
Peoples' Friendship University of Russia, Russia, Moscow
The Faculty of Medicine, Department of medical informatics
Scientific adviser(s): Ph.D. Lukyanova E.A.
Keywords: information technology, economics, medicine, intellectual
property, commercialization
: , ,
, ,
Abstract: In this article we present a theoretical evaluation of the
possibility of using the results of research activities in the real sector of
the economy by the example of Departments of medical informatics
research about the theoretical foundations of database management in
a life-science modeling

64 | III


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STANDARD PROCEDURES OF A MEDICO-BIOLOGICAL LABORATORY
MODEL DEVELOPMENT
Igumnova O.V.
Peoples' Friendship University of Russia, Russia, Moscow
The Faculty of Medicine, Department of Medical Informatics
Scientific adviser(s): Lukyanova E.A., PhD
Keywords:imitating modeling, virtual medico-biological laboratory,
educational process, standard modeling procedures
: ,
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Abstract:Medico-biological laboratories in Russian institutes of higher
medical education do not support effectively the educational process.
Searching of universal criteria and requirements to modeling of a virtual
medico-biological laboratory, and standard modeling procedures is an
actual problem for the medical students education.
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PRINCIPLES OF MAKING THE TRAINING COURSES WITH THE USE OF
VIRTUAL MODELS
Kalashnikova E. Y.
Peoples' Friendship University of Russia, Russia, Moscow
The Faculty of Medicine, Department of the medical informatics PFUR
Scientific adviser(s): PhD E.A. Lukyanova
Keywords: computer, simulation, virtual, medico-biological laboratory,
physiological, processes.
: , , ,
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Abstract:Computer simulation of the physiological processes creates an
alternative of the use of the biological objects, having recreated a great
deal of the physiological phenomena with the maximum proximity to
the real. "


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66 | III
HARDWARE-SOFTWARE SYSTEM FOR MEASURING THE LOAD ON THE
RODS OF ILIZAROV APPARATUS FOR DETERMINING THE STATE OF
BONE'S REGENERATION
Lagunina M.V., Trofimova M.A, Rusakov S.A
Volgograd State Technical University
The Faculty electronics and computer science, Department of computer
science
Scientific adviser(s): Ph.D., professor Muha Y.P.
Keywords:Ilizarov apparatus, bones regeneration, strain gauge, load,
graph analysis
: , ,
, ,
Abstract:Hardware-software system for measuring the load on the rods
of Ilizarov ap-paratus is worked out. System is based on strain gauge. In
the result of using this system the relationship between voltage on
strain gauge and load, which was on the rods, was received. There is the
possibility of optimization of process of treating with help of the
relationship and Egorovs M. F. discovery about intermittent increase of
regeneration.
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MATHEMATICAL MODEL REQUIREMENTS FOR STUDY OF
PHYSIOLOGICAL PARAMETERS VARIABILITY IN DRUG CORRECTION OF
FUNCTIONAL CHANGES CAUSED BY HYPERTENSION
Novoselov G.I.
Peoples' Friendship University of Russia, Russia, Moscow
The Faculty of Medicine, Department of medical informatics
Scientific adviser(s): Ph.D. Lukyanova E.A.
Keywords:hypertension, mathematical modeling, drug correction,
cardio-vascular system
: ,
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Abstract:Traditional empirical approaches used in modern medicine,

limit the depth of the experimental study of physiological processes.
Mathematical modeling is currently a topical area, contributing to a
detailed study.
An analysis of described models led to a quasi-stationary spatially
distributed model of closed cardio-vascular system.


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MINIMAL CHARACTERISTICS DETERMINATION WHILE CHOOSING
VIRTUAL LABORATORY PRACTICE.
Shimkevich E.M.
Peoples' Friendship University of Russia, Moscow
The Faculty of Medicine, Department of medical informatics
Scientific adviser(s): Ph.D. Lukyanova E.A.
Keywords:simulation models, computer laboratory practice.
: ,
.
Abstract:Information technologies development and innovative teaching
methods led to the possibility of such an alternative as a computer
laboratory classes for teaching medical students.
The experience of virtual laboratory selection for physiology studying is
described in this work.
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(Schneider & Morse Group),
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InterNICHE), Physiology Simulators (Georg
Thieme Verlag; Dr. Hans A. Braun), Digital Frog 2.0 (Digital Frog
International), Neuron ( Yale University, USA).

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70 | III
PLASMA VEGF CORRELATES WITH RIGHT VENTRICULAR FUNCTION IN
PULMONARY HYPERTENSION
Semmelweis University
Pk Judit, dr. Bikov Andrs, Dr. Karlcai Kristf, Dr. Cssza Gyrgyi,
Kovcs Dorottya, Prof. Losonczy Gyrgy, Dr. Horvth Ildik
Introduction: Pulmonary hypertension (PH) is a severe, progressive
condition of the small pulmonary vessels that leads to increased
pulmonary vascular resistance, right ventricular failure and death.
Previous studies suggest the role of vascular endothelial growth factor
(VEGF) in the pathomechanism of PH by several pathways. Still, the
relationship between airway VEGF and right ventricular function has not
been investigated yet.
Aims: We aimed first to evaluate the exhaled breath condensate (EBC),
as an airway sampling technique for VEGF detection in subjects with PH.
Then to measure the amount of the protein in plasma of patients
suffering from PH and healthy people. After that to compare EBC and
plasma VEGF with the best noninvasive clinical sign of advanced disease,
the ventricular longitudinal function, tricuspid anular plane systolic
excursion (TAPSE).
Methods: 10 PH patients (6 with idiopathic pulmonary arterial
hypertension, 2 with chronic thromboembolic pulmonary hypertension,
1 scleroderma, 1 congenital heart disease, aged 5817 years, mean
pulmonary pressure 58 21 mmHg), and 9 healthy controls (5013 year)
participated in the study. Plasma and EBC (Rtube, Charlotteswille, US)
were collected for VEGF measurements (Quantikine ELISA kit, R&D). In
the patient group echocardiography was performed to determine the
value TAPSE. Statistical analysis of the results was carried out after
logarithmic transformation by Mann-Whitney-test and Pearsoncorrelation.
Results: In EBC the VEGF concentration was under the limit of detection
in both groups. The level of plasma VEGF was significantly higher in the
patient group than in controls (13098 pg/ml, 3040 pg/ml, p=0,004).
We found significant correlation between TAPSE and plasma VEGF level
in PH patients (p=0,02, r=0,69).
Conclusion: We suggest, that decrease of VEGF with advanced PH
disease can be a result of deterioration of right ventricular contractility
accompanied with decreased pulmonary flow and wall stress. However,
EBC is not applicable to assess airway VEGF levels in PH patients.

ACTION OF IMMUNOMODULATORS DERINAT AND LICOPID ON

ACTIVITY OF LYZOZYME AS A FACTOR OF NON-SPECIFIC IMMUNE
RESISTANCE IN HELICOBACTER PYLORI INDUCED PEPTIC ULCER
DISEASE.
Kughan Govinden
[email protected]
Nizhny Novgorod State Medical Academy, Nizhny Novgorod, Russia.
Faculty of Overseas Admission, Department of General Medicine
Scientific Adviser(s): Professor V.V Kuzin, V. V. Dugina
Keywords: eradication, immunomodulator, contamination, lyzocim,
peptic ulcer disease.
Objectives:
1. To investigate the influence of immunomodulators Licopid (a
synthetic bacterial preparation) and Derinat (a preparation of nucleic
acid) in combination with antihelicobacter ""quadro-scheme""
therapy(QST) on efficiency of eradication in patients with peptic ulcer
disease(PUD)caused by Helicobacter Pylori(HP)
2. To reveal interrelation of lysozyme activity for the given group of
patients.
Methods:
1. This research is carried out on 70 patients within the age range of 2055 years with PUD of stomach and duodenum caused by HP.
2. Depending on types of received therapy, three groups of patients
have been allocated:(a) Group A (control group) consisting of 20 patients receiving ""quadroscheme"" therapy(QST) consisting of bismuth colloidal subcitrate,
omeprazole,amoxicilin,furazolidon.
(b) Group B of 25 patients receiving QST with Licopid

(c) Group C of 25 patients receiving QST with Derinat

3. Before and six weeks after application of preparations, the
histomorphological tests of biopsy material taken endoscopically from
stomach and duodenum and biotests(nephelometry) of saliva and
gastric juice from patients are done.
Results:
Six weeks after treatment, cytological tests reveals that in Group A,
eradication has been less expressed and came to light coccal forms
whereas in Group A and B the parameter of eradication is essentially
above and coccal forms HP are absent.Biotests done six weeks after
treatment reveals increased activity of lyzozyme in saliva of all
investigated samples. The maximal authentic increase of activity is
observed in Group C in which Derinat is applied (on 12, 3 % in
comparison with initial level). In Group B in which Licopid is applied,
activity of lyzozyme reliably increases (on 8, 1 % in comparison with an
initial level). The least increase lysozyme activity has been revealed in
Group A. At application of Derinat and Licopid the tendency of lysozyme
increase is marked in gastric juice. Activity of lysozyme increased 7.4 %
for Derinat and 3.6 % at application Licopid?. In control group, the
lowest activity of lysozyme is marked.
Conclusion:
Application of immunomodulators Derinat and Licopid on background of
antihelicobacter QST leads to increased eradication of HP. In all patients
with PUD in stage of aggravation, the low level lysozyme in saliva and
gastric juice is revealed. Usage of immunomodulators with QST tends to
increase activity of lysozyme in saliva and gastric juice, more expressed
at application Derinat

REMODELLING AND DYSSYNCHRONY IN ELITE ATHLETES

Klaudia Vivien Nagy
Semmelweis University, Heart Center, Budapest, Hungary
Keywords: echocardiography, elite athletes, hypertrophy, remodelling,
dyssynchrony
Introduction: Elite athletes may develop functional and structural
changes of the heart, which is described as physiologic remodelling, the
athletes heart syndrome. It is of high clinical priority to distinguish
pathologic remodelling, which may result in dyssynchrony.
Aim: The aim of this study was to evaluate the left ventricular
remodelling and diastolic function in athletes compared with
hypertrophic cardiography (HCM) patients. We also investigated the
presence of systolic and diastolic dyssynchrony in left ventricular
remodeling.
Materials and methods: 57 endurance-strength elite athletes (A), a
control group of 20 sedentary volunteers (SV) and a group of 12 HCM
patients underwent scientific transthoracal echocardiography. Left
ventricular (LV) end-diastolic and end-systolic diameters, LV wall
thicknesses, left ventricular systolic ejection fraction were measured.
The diastolic function was evaluated with measuring transmitral flow
velocities with by pulsed wave Doppler, and diastolic tissue velocities by
color coded tissue Doppler Imaging. We calculated indices describing LV
remodeling and hypertrophy: the LV mass index, hypertrophy index,
remodelling index and the systolic and diastolic sphericity indices were
also evaluated. Systolic and diastolic dyssynchrony was measured in the
six basal LV segments using color coded tissue Doppler imaging, as the
delay of the first and the latest basal myocardial segments in systole and
diastole.
Statistics: All data were measured three times, and presented as
meanSD. Differences between groups were tested for significance
using analysis of variance, with subgroup analysis by the Hochberg test.
A p<0,05 value was considered significant.
Results: LV end diastolic diameters (LVEDD) were significantly higher in
elite athletes and lower in HCM patients as compared to the control
group (A 54,54,4, SV 51,53,7, HCM 39,36,6mm; p<0,001).(Figure1.)
The end-systolic diameter (LVESD) was not significantly different in elite

 . , , , 2011 | 71
athletes, while lower in HCM patients (A 34,34,0 vs. SV 33,53,8 vs.
HCM 20,79,7mm, p=0,09; p<0,001).
The resting ejection fraction did not differ in elite athletes,
compared with the control group and the HCM patients (A 667, SV
65,47,2, HCM 66,912,5%; p=NS). The diastolic function, based on the
transmitral flow parameters, did not alter significantly in the three
groups (E/A: A 1,670,41, SV 1,410,32, HCM 1,540,5; p=NS), but the
diastolic tissue velocities were significantly lower in the HCM patients,
compared to the athletes and the control groups(E wave: A 7,871,5, SV
7,521,5, HCM 4,831,7 p<0,001).
The LV mass index was lower in the control group compared
to the athletes and HCM patients (A 134,819,7, SV 91,615, HCM
203,836,2g/m2; p<0,001).
No significant differences were found either in the systolic
and diastolic sphericity indices or in the LV remodelling index between
elite athletes and control group, while HCM patients showed
significantly higher values (Systolic sphericity index: A 1,660,17, SV
1,640,16, HCM 2,110,34 p<0,001; Diastolic sphericity index: A
2,090,35, SV 1,990,23, HCM 5,810,3 p<0,001; LV remodelling index:
A 0,960,21, SV 0,820,14, HCM 4,411,85 p<0,001).
Systolic and diastolic dyssynchrony were not found in any of
the groups (systolic S (n=40) 32,515,1, K 3019,5, HCM 33,225ms;
p=NS; diastolic S (n=40) 5836,3 K 58,342,8; HCM 60,523ms; p=NS).
Conclusions: In elite athletes - based on our results the LV hypertrophy
did not alter the LV geometry, did not result in pathologic remodeling or
diastolic dysfunction and did not cause systolic and diastolic
dyssynchony.

ANGINA PECTORIS WITH NEGATIVE CORONAROGRAM?

Microvascular dysfunction, arterial stiffness alterations and autonomic
neuropathy in the background
Bukosza E. N., Marcsa B., Gulcsi-Brdos P., Nieszner E. ,Kiss R. G., Prda
I.
Research Group for Inflammation Biology and Immunogenomics of
Hungarian Academy of Sciences and Semmelweis University
Military Hospital National Center for Health Services, Department of
Cardiology, Budapest
Keywords: angina pectoris, negative coronarogram, microvascular
dysfunction, autonome neuropathy, laser-Doppler
Introduction: Here we report our studies on a group of patients
suffering from typical angina pectoris, while having negative
coronarogram.
Aim: We aimed to study the background pathophysiological processes
by making measurements on their vascular system and the
cardiovascular autonomic regulation. Materials and Methods: Negative
coronarography group (NC, N=20, age: 587,62 y, typical angina
pectoris, positive exercise test, normal coronary arteries). Healthy
control group (C, N=20, age: 50,259,98 y). Microvascular function was
tested by laser-Doppler method (postocclusive reactive hyperaemia
(PORH); local heating (Heat) test). Arterial system function was tested by
Arteriograph (augmentation index (AIX); pulse wave velocity (PWV)).
Assessment of cardiac autonomic neuropathy was carried out by
cardiovascular reflex tests (Ewing).
Results: According to PORH test microvascular reactivity of NC group
was decreased compared to the C group. (NC: median: 409,06%, IQR:
322,0-515,05%; C: 508,56%, IQR: 415,72-638,84%, p<0,05). The
difference in the change of flow was not significant between NC and C
groups during the heating. As the Ewing tests report 86,67% of the NC
group was affected with autonomic neuropathy in variant degree, while
13,33% seemed intact. A significant negative correlation (r=-0,58,
p<0,05) between Ewing-score and PORH values related autonomic
neuropathy to microvascular alterations. We found arterial stiffness
significatly elevated in NC group compared to control (C) both in the
resistance vessels (AIX: NC: Median: 11,86% (IQR: -8,15-25,21 %), C:
Median: -10,27% (IQR: -42,1-14,36%), p<0,05) and in the aorta (PWV:
NC: Median: 11,54 m/s (IQR: 8,72-13,02 m/s), C: Median: 8,69 m/s (IQR:
7,44-10,73 m/s), p<0,05).
Conclusions: Substantial alterations in microvascular funcion and also a
complex vascular system disease are lying in the background of the
clinical status: typical angina pectoris with negative coronarogram.
Autonomic neuropathy also can act as a part of the pathomechanism.

THE RECENT ADVANCES IN CARDIOVASCULAR MEDICINE - THE

REGENERATIVE MEDICINE WAY
Amit Tripathy
[email protected]
Veer Surendra Sai Medical College, Burla, Sambalpur, Odisha, India
Faculty of Medicine
Scientific Adviser(s): Dr. Bhabagrahi Rath
Keywords: myocardial infarction, stem cell, halt progression, heal, revert
to normal, autologous
The Romeo and Juliet saga had its foundation from a very integral,
indispensible, incomparable part of our body which is now surrounded
by the perinneal garbage that smells foul from a majority of households
from the world- ?The Heart?.
With the missiles of chemotherapy, it has been possible to put the
damage caused to be in control. However, reverting the damaged heart
back to normal has been a nightmare for scientists throughout the
world. May it be a mighty valve prolapse or vegetations in the valve,
may it be congenital heart defects or ischaemic cardiomyopathy, may it
be peripheral vascular diseases or defects in the conduction system, the
heart has always been in a constant threat with a long searched hunt
coming to an end with the advent of almost a decade of research- ?The
Regenerative Medicine?. Regenerative medicine is the future of
cardiovascular medicines which not only ensures care but also ensures
that the heart becomes perfectly 100% functional. The viability, the
practicability, the efficacy and the reproducibility of the stem cells was
the cause which led to Dr.Martin Evans winning the Nobel Prize in 2007.
REGENERATIVE MEDICINE AND MYOCARDIAL INFARCTION
Myocardial infarction has since ages been a disease of the masses
especially of the developed world with an incidence of 17,600,000 cases
of coronary heart diseases from the United States itself with 8,500,000
being those suffering from myocardial infarction. It was even reported
that cardiovascular diseases claimed 151,000 americans under the age
of 65. The conventional treatment to this disease which presents as a
acute attack often cognomened as ?THE HEART ATTACK? accompanied
by angina pectoris has until the past decade been based on
pharmacotherapeutics with drugs like diuretics, beta blockers,
angiotensin converting enzyme inhibitors, angiotensin receptor
blockers, calcium channel blockers etc. Regenerative medicine is the
voice of the decade and the panacea for the future. It is one of the most
efficacious, most promising gifts to the world of medicine which has its
advantages burying the disadvantages of the commonly used drugs. Its
disadvantages are the stimulating factor for which extensive research is
being undertaken in animal models like primates, mouse, rat, albino
rabbit, swine etc. so as to nullify the disadvantages.
The source and the method
Stem cells mostly the hematopoetic stem cells<HSCs> have proven to be
the most viable to be used in practical clinics. There also has been
reports regarding the use of mesenchymal stem cells<MSCs>, adipose
tissue derived stem cells and embryonal stem cells<ESCs> to regenerate
cardiac myocytes in myocardial infarction. The stem cells being
pluripotent divide into the cardiac progenitor cells which then
differentiate into endothelial and cardiac lineages as well as influences
the local microenvironment by release of paracrine factors<THE
PARACRINE HYPOTHESIS>. The HSCs conventionally derived from the
bone marrow and now from the umbilical cord blood owing to the
procedure being non-invasive and easily available are injected into the
damaged myocardium after clearing the coronary arteries from the
atherosclerotic plaque< by balloon angioplasty>.
The prognosis of using stem cells for regenerating the damaged
myocardium infact is very good as it not only promises early cure but is
the only tool available to regenerate the damaged myocardium.
Extensive research is on in each and every corner of the world and it is
not far when the world gets regenerated under the aegis of regenerative
medicine.
REGENERATIVE MEDICINE AND THE VALVES OF THE HEART
An estimated 275,000 patients worldwide undergo heart valve
replacement surgery each year because of valve abnormalities they
present due to a variety of pathological causes (eg infections,prolapse)
that can result in stenosis and regurgitation. Either process burdens the
heart and can cause heart failure.

72 | III
There are two main types of artificial heart valves used conventionally
for implantation, the mechanical and the biological valves (porcine,
bovine, equine, human donor valves).However, artificial heart valves
require lifelong treatment with anticoagulants (warfarin, LMW Heparin)
for blood clot prevention in the valves, even though theoretically they
can last indefinitely. Nevertheless, in the case of children, surgeries for
valve replacement are more frequent because of the incompatibility the
valve presents due to fast tissue growth in parallel with the aging. On
the other hand, porcine valves, need replacement after 10-12 years the
most because of the loss of durability, so they are not a permanent
solution. The fact that the porcine life span is about 10-12 years explain
the induce of porcine durability over the years.
Many scientific teams work on development of heart valves using the
technology of stem cells (Mesenchymal Stem Cells-MSCs , Multipoten
Adult Stem Cells-MASCs, Progenitor Cells, Cardiac Stem Cells-CardiacSCs,
Hematopoietic Stem Cells-HSCs etc.). Scientists usually use umbilical
cord derived stem cells, because they are easy to collect and less prone
to be rejected by the human organism.
In two different researches MSCs and ASCs derived from bone marrow
and umbilical cord respectively were isolated, tested about their antigen
expression profile and morphology and were stored. In the meantime, a
biodegradable scaffold which would give the shape to the valves was
constructed by scientists. Stem cells that were put into the scaffolds
managed to differentiate into cardiac tissue and also exhibited
characteristics of extracellular matrix. The newly engineered valves were
tested for functional efficacy in blood flow volume and pressure. After
that, the valves were placed into the pulmonary position of sheep during
a cardiopulmonary bypass. Valves were evaluated by echocardiography
and were explanted at 4 and 8 months to be examined with histology
and immunohistochemistry techniques. The results showed that the
valves were fully functional.
In addition, the CardiacSCs, which were found to express the cell-surface
markers c-kit, Sca-1, isl-1 and telomerase, seem to be very promising
referring to the cardiovascular applications of regenerative medicine.
They have the ability to differentiate into endothelial, endocardial,
smooth muscle, conduction system, right ventricular and atrial myogenic
lineages during the development of the embryonic heart. Thus, the
procedure of implanting cells generated from CSCs would have minimal
risk of immune rejection or teratoma formation. Unfortunately, no
clinical data using CSCs are available yet, so we cannot be sure about the
possible long-term in vivo function of the differentiated CSCs for the
time being.
As for the Embryonic Stem Cells-ESCs, even though they have the ability
to differentiate into any cell present in the adult organism, they are not
currently used in the regeneration of the myocardium or parts of it
because of their ability to form teratomas and cause immunological
rejection. Thus, it is out of the question to use them in vivo for the
treatment of cardiovascular diseases of humans according to the
existing data.
The fact that the regenerated valves can equally replace totally
damaged or abnormal valves can help us overcome problems such as
frequent surgeries, usage of drugs like immunosuppressants
(e.g.glucocorticoids, cytostatics, antibodies etc.) and anticoagulants
(e.g.heparin,
warfarin) ,
immunodeficiency
caused
by
immunosuppressants and even heart transplant.
`1
CONCLUSION
?
Wide spread global research on the use of especially HSCs for
healing diseases of the heart has been very promising
?
Success in animal models, especially mice, has opened up a
wide array of speculations that finally man has an abracatabra to cure
the heart
?
Clinical trials and practical use in patients especially those
suffering from MI and Valve disease have shown success to the par of
80-90%
?
The heart has some resident progenitor on cells whose
therapeutic significance or physiological function has not yet been
discovered
?
Nanoparticles and use of biodegradable scaffolds might
improve the prognosis as site specific delivery systems

CLINIC-MORPHOLOGICAL PARALLELS AT LOW BACK PAIN.

Smirnov E., Ibrohimov Sh.I., Yakovlev M.V., Sadikov I.H., Kornilova L.E.

Department of neurological diseases and neurosurgery PFUR, Moscow

One of the more evident problems in the treatment of low back pain is
the insufficient efficacy, of the numerous methods available, in relieving
the painful syndrome, which is tied to an absence of concrete concepts
concerning the pathogenesis of the given illness. The morphological
changes (MC) of lumbar intervertebral discs, as detected by magnetic
resonance imaging (MRI), do not frequently correspond to the degree to
which the painful syndrome is expressed.
Aim: to study the correlation of clinical manifestations of low back pain
(CMLBP) to various quantitative parameters of MC of the lumbar spinal
column: size of maximal herniation (SMH), total of extrusion sizes (SES)
and the amount of extrusion (AE).
Materials and methods: 147 patients with CMLBP were under
observation. All patients had undergone a detailed collection of
anamnesis, their neurological and neuroorthopedic statuses were
investigated. The painful syndrome was assessed by the use of an
analogous visual scale (AVS), a Russian adaptation of the McGill pain
questionnaire (MGPQ), of the body scheme. The MC were analyzed by
data from MRI. For the assessment of anamnestic and clinical data
depending on the various quantitative MC of lumbar osteochondrosis,
all patients were divided into two groups depending on the SMH: up to
7mm and above 7mm. Furthermore, all patients were subdivided into
two subgroups by the SES: up to 12mm and above 12mm. Finally, the
patients were divided into further two subgroups depending on the AE:
1 to 2 and above.
Results: All patients expressed various reflectory vertebral and pelvic
syndromes of CMLBP. The mean duration of illness was 11.5 0.9 years,
amount of exacerbations per year 2.9 0.2 times, duration of last
exacerbation 1.6 0.1 month. It was noted that the duration of illness
and frequency of exacerbations per year were in correlation with the
sum of MC of the spinal column. The duration of exacerbation was
independent of MC. The intensity of the pain at CMLBP, did not
correlate with the MC of the spinal column.
Conclusion: The chronic character of the disease progression, its
duration and frequency of exacerbations per year depended on the sum
of MC of the spinal column, and were not tied to SES. During the periods
of exacerbation, the relevance of MC in the form of herniations and disc
protrusions in the development of CMLBP was leveled out.
Abstract
Clinic-morphological parallels at low back pain.
Smirnov E., Ibrohimov Sh.I., Yakovlev M.V., Sadikov I.H., Kornilova L.E.
It was shown clinic-morphological correlations of the patients with low
back pain, with different sizes of extrusion of lumbar intervertebral
discs.
Key words: lumbar osteochondrosis, painful syndrome.

I .
. .
[email protected]
.
, 1
, ,
, 2
- . ,
3
() (): ..., .. 1, ...,
.. 3, ..., .. 2,
COMBINATION OF TRANSESOPHAGEAL PACING AND
ANTIARRHYTHMIC DRUGS FOR I TYPE ATRIAL FLUTTER EFFECTIVE
TERMINATION.
Reynbakh O. A.
Moscow regional Center for Cardiology, Zhukovsky, Russia1
Peoples Friendship University of Russia, Faculty of Medicine,
Department of general pathology and pathologic physiology, Moscow 2
Bakoulev Center for Cardiovascular Surgery RAMS, Moscow, Russia3
Scientific Adviser(s): A.V. Tarasov1 MD, PhD; K.V. Davtyan3, MD, PhD; M.
L. Blagonravov2 MD PhD

 . , , , 2011 | 73
Keywords: type I atrial flutter, transesophageal pacing, amiodarone,
procainamide
: I ,
, ,
Abstract: The effectiveness of transesophageal pacing (TEP) with and
without
antiarrhythmic
drugs
(Amiodarone,
Procainamide)
administration in termination of persistent isthmus-dependent AFL was
studied. 70 consecutive patients with persistent type I AFL were
included in the study. All patients underwent TEP in order to restore
sinus rhythm. Depending on antiarrhythmic drug and TEP combination 3
groups of patients were formed. Results: Sinus rhythm was restored in
18 (75%), 19 (82.6%) and 8 (34.8%) patients of groups 1
(TEP+amiodarone), 2 (TEP+procainamide) and 3 (TEP) respectively. In 5
(20.8%), 4 (17.4%) and 10 (43.5%) patients of groups 1, 2 and 3
respectively AFL was converted to persistent AFIB. TEP was ineffective in
1 (4.2%) and 5 (21.7%) patients of groups 1 and 3 respectively.
Conclusions: Our findings showed high effectiveness of TEP with
antiarrhythmic drugs administration in termination of persistent typical
AFL.
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, .


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[email protected]
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..
APPLICATION OF THE NEW MEDICAL TECHNOLOGY ""INTRAOSSEOUS
BLOCKADES"" IN A CASE OF DISTAL SYMMETRICAL DIABETIC
POLYNEUROPATHY"
Zakirov I.I., Arsiukhin N.A.
Peoples' Friendship University of Russia, Russia, Moscow
The Faculty of Medicine, Department of neural diseases and
neurosurgery
Scientific Adviser(s):Ph.D., prof. Sokov E.L., Ph.D, prof. Kornilova L.E.
Keywords:diabetic neuropathy, neuropathic pain, intraosseous
blockades.
: ,
, .
Abstract:The high efficiency of intraosseous blockades was revealed in
the treatment of pain in 18 patients with distal symmetrical diabetic
polyneuropathy. Duration of the catamnesis was 1 month.
: ()
.
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: ,
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Symptoms Score (TSS).
TSS
, 1 .
,
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:
TSS 10,852,15,
6,61,1 .
()
: 6,81,7 ,
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5,62,7 , 3,82,9 .
TSS
3,482,28,
1,81,2
.

74 | III
1,21,4 , 0,61,1 ,
2,11,5 , 1,31,5 , 0,800,9 .
.
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40 .
.., ..
[email protected]
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THE SPREAD OF ISCHEMIC DISEASE IN PATIENTS WITH PULMONARY
TUBERCULOSIS. RESEARCH PERIOD IS 40 YEARS.
Arsentyeva N.V.,Abdulhaev V.V
Peoples' Friendship University of Russia, Russia, Moscow
Medical faculty, tuberculosis
Scientific Adviser(s):Ivanova Z.A., Koshechkin V.A.
Keywords:ischemic, tuberculosis
: ,
Abstract:There is a retrospective analysis of examinations of men with
pulmonary tuberculosis and concomitant ischemic disease at the age of
50-59. The results of studies conducting for more than 40 years (1972,
1998 and 2011) report that spread of ischemic disease signs in men with
pulmonary tuberculosis are still the same. So, ischemic disease is an
actual problem among pulmonary tuberculosis patients.

,
50-59 ,
20 . , I, II, III
(). 1972, 1998
2011 .
: ( , ,
).
Q/QS, ST,
, AV-, ,

G. Rose, H. Blackburn.
,
,
: 31,9% 1972 ; 21,0% 1998 26,6% 2011.

() : 1972
1998 5,0%, 2011 2,0%.
,
40 ,
,
. , ,
,

() .

.., .., .., ..
[email protected]


, , .
, 2
() ():..., ..,
..
RISK FACTORS OF PATIENTS' MORTALITY WITH MYOCARDIAL
INFARCTION IN THE ACUTE AND REMOTE PERIODS
Sinaiskaya M.A., Fedorov V.V, Chapina N.G,Bogomlov A.N.
Komi Branch of the State Educational Institution ""Kirov State Medical
Academy, Federal Agency for Health Care and Social Development "",
Russia, Syktyvkar.
Medical Faculty, Department of Internal Medicine 2
Scientific Adviser(s):PhD, Associate Professor Kurochkina O.N.,
Boyankova N.M.
Keywords:Cardiology, myocardial Infarction, dynamics, structure,
disease, the analysis of the register, death rate, survival, mortality, risk
factor, uptake, an acute period, a remote period.
: , , ,
, , , ,
, , , ,
.
Abstract:The register of patients with myocardial infarction has been
examined. It is carried out in the Polyclinic 3 in Syktyvkar. Myocardial
infarction cases between 2003-2009 are analyzed, some mortality risk
factors in the acute and remote period are detected.

7 .
. ,
, 3 .
2003 .
(), 2003 2009 .,
, , ,

.
Microsoft Excel 2007 .
Biostat,
, -, z-,
,
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. 999
, 559 (56%), 440 (44%) (=0,000).
61,9811,74 , 70,7110,16 (=0,02).
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(=0,000).
. 180 (18%),
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: 2003 .
17 (20%), 11(20%), 2009 . 12 (20%) 9
(23%) . , ,
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70,9411,17 , 66,611,5 ,
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=0,006), 70 ( 70 12%, 70
26%, =0,000).
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(=0,000). Q 114 (24%),
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63 (20%).
,
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88 (14%), 6 65 (38%) (=0,000).

 . , , , 2011 | 75

62 (10%), - 118 (31%) (=0,000).
.
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. 1-
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(6% 3 ), 4- - 33 (6%
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- 77% (158 ),
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(=0,000). - 107 (47,5%) 97
(52,5%). 23%; - 28% (=1,2)
(=0,1). 67,88,6 ,
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. 7-
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88%, 7- 45% 72% (<0,05). 1-
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65 74%, 7- 73% 45% (<0,05).
:
1.

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.
2.

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3.

:

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[email protected]
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HCV LIVER CIRRHOSIS ENCEPHALOPATY: DIAGNOSTICS &
TREATMENT ABILITIES
Akulich K. V.
Belarusian State Medical University, Belarus, Minsk
The Faculty of General Medicine, Department of infectious diseases
Scientific Adviser(s):Ph. D. Yagovdik - Telezhnaya E. N.
Keywords:latent encephalopaty, psychosocial condition, lactulose,
ornithine aspartate
: ,
, ,
Abstract:Hepatic encephalopathy - typical syndrom for patients with
liver diseases; is assigned as a spectrum of psychoneurological
abnormalities; is characterized with personality changes, intellectual
damages and depressions.
,

;
, .

,
,
.


. 62
.
: ,
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, ,
, ,
(Sickness Impact Profile SIP).
1.


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Child-Pugh.
2.

,
,
,
.
3.



.
4.
,
.
5.

,

.
,
.

-

. ., . .
[email protected]
-
,
() ():. . ,

NERVOUS SYSTEM DESEASES IN HIV INFECTED PATIENTS AND THEIR

DIAGNOSTICS
Demyanyuk R. V., Zolotaryov P. V.
Ivano-Frankivsk National Medical University
The Faculty of Medicine, Department of Infectious deseases
Scientific Adviser(s):Ph.D. Gryzhak I. I.
Keywords:HIV, diagnostics, Nervous system deseases
: -,
-
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62 -
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I, II III -,
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76 | III
:

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.

BPLAB
.., ..
[email protected]
, ,

() ():..., .., . .
., ..
NON-INVASIVE VALIDATION OF AN OSCILLOMETRIC DEVICE BPLAB
FOR CENTRAL BLOOD PRESSURE AND ARTERIAL STIFFNESS
MEASUREMENT
Kretsu V.N., Klyuchnikova O.S.
Peoples' Friendship University of Russia, Russia, Moscow
Department of Propaedeutics of internal diseases PFUR
Scientific Adviser(s):professor Kobalava J.D., professor Kotovskaya Y.V.
Keywords:arterial stiffness, applanation tonometry, oscillometric
tonometry, pulse wave velocity.
: , ,
, ,
.
Abstract:The aim of this research was to compare two non-invasive
methods of tonometry by using gold standard SphygmoCor and
BpLab in two groups adult hypertensive patients without
cerebrovascular disease, peripheral vascular disease, dysarrhythmias,
valvular heart disorders, cardiac decompensation and young
normotensive patients.
.
()

. BpLab (
, , ), -

,
(PWV,/),
( ...),
(Aix,%),
.

.


(ARTERY)
SphygmoCor (AtCor Medical, ).
: BpLab SphygmoCor
:
(PWV,/), (Aix,%),

(Aix
,%),

(, ),
(ED,), (SEVR, %) ARTERY2010.
:
1.

BpLab SphygmoCor;

2.
.
. 44
16 78 (47,77,8) BpLab SphygmoCor 3 ,
15 . (22-23)
, 10
.
, ,
BpLab.
BpLab SphygmoCor,
.

. ,
Exel 2007 MedCalc v11.5.1.0.
. BpLab SphygmoCor
(r),

:
R=0,921, R=0,916, RAIX=0,881, RAIXao=852, RED=0,703,
RPWV=0,653, RSEVR=0,507. -,
, ,
(2SD) 5%
(PWV-95%, Aix-97%, Aixao-95%, -97%, -95%, SEVR95%, ED-97%).
. BpLab

SphygmoCor,
."

.
..
[email protected]

,
() ():... - ..
THE SUBSEQUENT TREATMENT OF THE PATIENTS WITH THE CHRONIC
HEPATITIS C AFTER LIVER TRANSPLANTATION.
Medvedeva E.S.
Belarussian State Medical University
The Faculty of General Medicine, Department of infectious diseases
Scientific Adviser(s):Ph.D. Yagovdik-Telezhnaya E.N.
Keywords:Hepatitis , liver transplantation, recurrence,
immunosuppression, antiviral therapy
: , , ,
,
Abstract:During the given research two questions were studied mainly:
strategy of treatment of the patients who had liver transplantation, and
the ways of depression recurrence's agression of the hepatitis C after
the liver transplantation.

.
2

. 2008
2010 10
, .
2 . International Liver
Congress, 2010 : 1 80%, 5 72%, 10
- 56%.
:

.
: ; ,
;

.
,
13% 1-4
50% - 2-3 .
,
35% (

 . , , , 2011 | 77
International Liver Congress, 2010). ,

+,
80% ,
40%- .

, . R.J.Firpi
,
46% , 27%
. G.Ghobrial


.

.
: 1.
.
2.
.
3.

+."

(
-)
.
[email protected]

,
() ():... .., ...
.
STROKES PROPHYLAXIS:WHAT DO SVERDLOVSK OBLAST'S PEOPLE
KNOW ABOUT IT?
Poltavskaya T.S
Ural State Medical Academy
The Faculty of Medicine, Departament of neurology and neurosargeons
Scientific Adviser(s):Ph.D Prasdnichkova E.V, Ph.D Volkova L.I.
Keywords:Stroke, Preventive measures, poll, preventiv programs
: , , , .
Abstract:Stroke thrombosis is a dangerous disease leading to disability,
incapacity for work and death. Preventive measures such as community
outreach programs are necessary for decreasing number of cases. For
investigations peoples knowledge about methods of blood-strokes
prophylaxis opinion poll was holden in Kamensk-Uralsky. According to
the polls data more that quarter of apoplectic doesnt know what the
cause of stroke thrombosis is and triens of them cant describe its signs.
More then 70% dont know anything about blood cholesterol level.
Analysis of polls data is necessary for correcting existent strokes
prevention programs.
-,

,
.


7,47 1000 2,2 1000 .

,


.

.

, ,
.
,
,

. 15 80 , - 55,9 ,
: 49% 51% .

: ( ),
, , ,
, .
,
30%, ( 25-29,99)
33%, 1 ( 30-34,99) 13%,
2 ( 35 39,99) - 7%, 3
( 40) - 4% .
57%. (
140 . .) 69% ,
35% ,
13% .
37%. 35%;
2%, 54% .

:
- 12%, - 11%,
-16%,
- 10% . 38, 8%
,
86%
.
45, 6%, ,
,
.

.
,
.

. ,
(69%);
(57%),
(35%) : (16%),
(12%), (11%).
,
.
, .

. ,

.
,
.

-
.., ..
[email protected]
, ,
,

() ():..., ..
SUSTAINED VIRAL RESPONSE FOR PEGYLATED INTERFERON
TREATMENT OF CHRONIC VIRAL HEPATITIS C IN HIV-POSITIVE
PATIENTS.
Stepanova A. G., Kudyakova D.V.
Peoples Friendship University of Russia, Moscow.
The Faculty of Medicine, Department of Infectious diseases PFUR
Scientific Adviser(s):D. Sc., professor G.M. Kozhevnikova
Keywords:viral hepatitis C, HIV- infection, viral response.
: , ,
Abstract:The co-infection of viral hepatitis C and HIV-infection is often
diagnosed in the intravenous drug users. The efficiency of antiviral
therapy is estimated by constant viral response. The aim of the research
work was to determine frequency of the constant viral response in

78 | III
HCV/HIV co-infected patients. We analyzed the dynamics of
concentration ALT, AST and HCV RNA in the 15 patients with co-infection
and 15 patients with mono-infection HCV. The results show that the
patients with co-infection (viral hepatitis C, HIV- infection with
CD-4
count > 350 cells/ml) during for pegylated interferon treatment have
got normal level of ALT and AST, sustained viral response has been
achieved in 53% of patients. In patients with mono-infection HCV viral
response was reached in 60%. Conclusion: patients with viral hepatitis C
and HIV- infection stage 3 sustained viral response is registered with
the same frequency as in the patients with HCV mono-infection.

()

().
.., ..
[email protected]
, ,
,

() ():..., . .,
..

:

.
()
().
, -
,

.

.
.
(
6 ),
(, ),
.
:
-.
:
30 .
: - 15
- ( + -)

, 15 - .

, (
,), 4

(). ,
4, 12, 48 6
.
: 1 38 , 2
- 29 , 80% 20%
. .
1 -
- 3
(),
.
-2 () 180 1
/ ,
( 800 1200 /).
1 1,6 , 2
- 1,3 . 1
1,3 , 2 .
1 1 300 /
11 000 000 /, 2 22 600 / 7 000 000
/. 4-
53% 70%
. 12 80%
1- ,
(100%). 1
6
53% , 2
60 % .

:
20%
(+-), 13% .
:
- 3

,
- .

PREVALENCE OF CHRONIC KIDNEY DISEASE IN PATIENTS WITH POOR

CONTROL OF ARTERIAL HYPERTENSION.
Tarasova T.S., Timohina A.I.
Peoples' Friendship University of Russia, Russia, Moscow
The Faculty of Medicine, Department of Internal Medicine
Propaedeutics
Scientific Adviser(s):M.D, associate professor Efremovtseva M.A., Ph.D.
student Pigarev J.A.
:

().
: 221 ( 7012,9)
() ( 14825,6;
85,112),
3 , .
: (n=163)
2 (n=48).
, ,
,
,
.
KDOQI ( ,
,
,
() ,
MDRD) 3 .
: (n=211)
57,5%. 55,8%
(n=91), 3 (23,9 %) 2 (22,7 %)
, 1 (8%),
4 1,2% . 44,2%
,
(60-90 //1,732)
.
62,2% (n=30),
3 (29.2%) 2 (27%)
, 4 2,1%, 1
4,2% . 37,5%
, 20,8% (60-90
//1,732) .
:
,
.

, ,
.


.

20032009 .
.., .., .., ..
[email protected]


, , .
, 2
() ():..., ..,
..

 . , , , 2011 | 79
INCIDENCE DYNAMICS WITH THE MYOCARDIAL INFARCTION IN 2003 2009 .
Fedorov V.V, Sinaiskaya M.A., Chapina N.G, Bogomolov A.N.
"Komi Branch of the State Educational Institution ""Kirov State Medical
Academy, Federal Agency for Health Care and Social Development "",
Russia, Syktyvkar"
Medical Faculty, Department of Internal Medicine 2
Scientific Adviser(s):PhD, Associate Professor Kurochkina O.N.,
Boyankova N.M.
Keywords:Cardiology, myocardial Infarction, dynamics, structure,
disease, the analysis of the register, uptake, risk factor.
: , , ,
, , , ,
.
Abstract:The register of patients with myocardial infarction has been
examined. It is carried out in the Polyclinic 3 in Syktyvkar. The heart
attack cases occurred between 2003-2009 are analyzed, the prevalence
and incidence in different groups of population are studied.
-
2003-2009 . .
. ,
, 3 .
2003 .
(), 2003 2009 .,
, ,
, , .

Microsoft Excel 2007 .
Biostat,
, -, z-, .
.
999 , 559 (56%), 440
(44%) (=0,000). 61,9811,74 ,
70,7110.16 (=0,02). 2003 .
2009 . ( 10000 ) 25,9 16,2
(=0,07), 38,5 22,0 (=0,02), 17,6
11,7. Q 468 (50,27%) , Q
- 463 (49,73%). 664 (68%),
- 314 (32%) (=0,000). Q
52% (275) , Q 48% (250); 66% (362),
34% (183) (=0,000). Q
48% (193) , Q 52% (213); - 70%
(302), - 30% (131) (=0,000).
- 46% (381), - 7%
(55), -23% (191), - 12% (102), - 4% (62),
- 4% (29). 1- 6
636 (66%), 7 24 95 (10%), 24 - 236 (24%) (=0,000).
1- 6 413 (64%), 7 24
- 58 (9%), 24 - 174 (27%), - 216
(71%), 34 (11%), 56 (18%) (=0,000).

() - 613 (61%), 314
(31%), - 167 (17%), 143 (14%),
- 84 (8%).
613 (61%), 386 (39%)
(=0,000). 297 (63%), 262
(37%) (=0,000); - 274 (72%), 124 (28%)
(=0,000). Q 275
(47%), Q 304 (53%). Q
193 (55%), Q 159 (45%) (<0,05).
( 365 )
- 143 (39%),
77 (21%),
56 (15%), 35 (10%), 28
(8%), - 23 (6%)
27 (7%).
:
1.

: , - 60 ,
70 ,
, .. .

2.

,
.
3.

.
4.

.

,
..
[email protected]


() ():., ... ..
POTENTIAL OF NONINVASIVE BIOELECTRIC IMPEDANCE ANALYSIS IN
DIAGNOSTICS OF ABSCESS, INFILTRATION OF SOFT TISSUES
Fedosov A.E.
Smolensk State Medical Academy
Treatment Department
Scientific Adviser(s):D.M. Borsukov A.V.
Keywords:Noninvasive bioelectric impedance analysis, abscess,
infiltration
: , ,

Abstract:Potential of noninvasive bioelectric impedance analysis in

diagnostics of abscess, infiltration of soft tissues. This research deals
with potential of noninvasive bioelectric impedance analysis in
diagnostics of abscess, infiltration of soft tissues. It is an attempt to
review efficiency, usability, harmlessness, self-descriptiveness of
noninvasive bioelectric impedance analysis by example of regular
surgical pathology.One of the main idea of the research is demonstrate
visually perspective of adoption of this screening method in daily
medical practice for diagnostics of quite a number of surgical and not
surgical pathology.
:

,
.
:

,
;
, .
: 16
( 7 9
24-58 )
45-50 .
.
:

,
8 , 6
, ,
, 2
.
: ,
,
,
.
, ,

, ,
.
. ,

.

80 | III

HBSAG HBV:
.P., .., ..
[email protected]
, ,
,
() ():... .., ...
..
QUANTITATIVE HEPATITIS B SURFACE ANTIGEN IN CHRONIC HBV
CARRIERS: PROSPECTS OF APPLICATION
Fedotova A.R., Chuyko N.A, Alimova A.V.
People's Friendship University of Russia, Russia, Moscow
The Faculty of Medicine, Department of Hospital Therapeutics
Scientific Adviser(s):M. D. Ogurtsov P.P., Ph. D. Policarpova T.S.
Keywords:quantitative hepatitis B surface antigen, hepatitis delta virus,
serological diagnostics
: HBsAg , ,

Abstract:Quantitative hepatitis B surface antigen is a new method of
serological diagnostics that can be used to monitor HBV infection. HDVRNA correlates positively with HBsAg. HBV-DNA levels showed no direct
correlation with quantitative HBsAg. There is no correlation between
HBsAg levels and biochemical parameters
HBV- ,
.
HBsAg
, ,
. , 1
, 200
. 50
2 .
, B
D,


.
HBV- HBsAg
(epatitis B surface Antigen). HBsAg
6 HBV-,
, 200
HBsAg.
,
.
HBsAg -
.
HBsAg
HBV.

.
HBsAg
HBV- ,

HBsAg. HBsAg-
HBsAg.
: HBsAg

HBsAg
-
HBsAg.
. 25
( HBsAg,
HBeAg, ,
, ).

HCV-. HBsAg-
HBsAg
, .

D 9
. 2 : (3 )
(6 ) D.
(36,673,3 35,837,69 , p=0,85),
(31,6714,64 25,679,1 /, p=0,63), (29,676,24 /
20,673,59 /; p=0,17), (5,250,05
5,31 ; p=0,18) (17525 369,05379,01
; p=0,31).

Microsoft Exell ( ,
t-
).
. HBV-
30,1416,87 /, 26,229,41 /,
1209,561187,21 ,
5,521,07 ,
F0 METAVIR.
HBsAg HBV- 0,64
47818,32 /.

HBsAg
(r=0), (r= -0,05), (r= -0,1), (r=
0,29) .
HDV- HBsAg (1243,67;
32042,06 47818,32 /; 27034,68 19340,89
/) , HDV (207,85; 252,94; 454,45; 647,29; 1570,87 8100,97 /;
1872,42822,26 /),
(=0,21).
:
HBV- HBs-Ag
0,64 47818,32 /.
HBsAg
,
.
HDV-
HBsAg , HBV-.

:


.., .., ..
[email protected]
, ,
,
() ():... .., ...
..
INTERFERON INDUCED NEUTROPENIA: THE CHOICE OF METHOD OF
CORRECTION AND EFFICACY OF ANTIVIRAL THERAPY FOR CHRONIC
HEPATITIS C
Chistyakova A.V., Ogurtsov P.P.,Alpidovsky V.K.
Peoples' Friendship University of Russia, Russia, Moscow
The Faculty of Medicine, Department of therapy
Scientific Adviser(s):Ph.D. Ogurtsov P.P., Ph.D. Alpidovsky V.K.
Keywords:leukopenia, neutropenia, chronic viral hepatitis C, antiviral
therapy, inductors of leucopoiesis, hematologic complications
: , , ,
, - ,
.
Abstract:The problem of hematologic complications of chronic hepatitis
C treatment is very actual nowadays. These complications are the most
severe.
The basic way to struggle with hematologic complications is
appointment of hemopoietic factors at already developed cytopenia.
The main disadvantages of such treatment are the delay of leucopoiesis
inductors action and increase of a total cost of the course treatment.
Correction of the medicine dose may be an alternative in this case.
. () -
,

 . , , , 2011 | 81

. ,
1- HCV,
-
( ) 40%.
.


,
.

.

.
.

.
. ,
( ) -
1
,
.
.
- 60 1 HCV
-2b ,
: -2b 1,5 //.
15 //.
F0-F2

2,6 106 .
.
.
78% (47 60 .),
-
12 24 ,
.
-2b
(0,8 0,1) 109/
() 3% (2 ),
. 34
, 13
- .
33 (
6 ).
-2b 70% (24 ),
- 69%
(9 )
,
(p>0,2).

(3 13 ),
(33 47 ), p<0,05 ( ).
.
(78% ),

3%,
.


. ,
-
,
.
,
-2b,

.
,
.

1

.
[email protected]

,,

() ():..., ..,
..., ..
FEATURES OF HEADACHES IN STUDENTS FIRST-YEAR MEDICAL SCHOOL
Kornilova A.A
Nizhny Novgorod State Medical Academy, Nizhny Novgorod, Russia
Therapeutic faculty
Scientific Adviser(s):MD, Professor Grigoryeva V.N, PhD Egorova E.A

Keywords:ache, students, survey Headache Test.

: , , HeadacheTest
Abstract:80 first year students of medical faculty medical academy
performed a computer test with Headache Test. Questionnaire revealed
a high incidence of cephalgia students. The most frequently diagnosed
tension headache, cervicogenic headache and migraine.
:
, ,

, ,
.

,
,
,
.
,
, ,
.

1
.
:
HeadacheTest 80 (57
23 ) 1
.
18,21,5 .
,

,
.
,
55 (68,8%), 25
(31,2%). 38
(47,5%), - 17
(21,3%). 38
(66,7%), - 17 (73,9%) p > 0,05.
15 (18,8%).
25 (31,3%)
, 16 (20,0%)
- , 13 (16,3%)
. ,
5 (6,2%)
, 1 (1,2%)- . 16
(20,0%)
.

. ,
6 23 (26,1%),
19 57 (33,3%).
5 23 (21,7%), 8 57 (14,0%).
,
8 23 (34,8%), 8 57
(14,0%) (p<0,05). 12 57 (21,0%) 4
23 (17,4%) .
: , 68,8%
1 .
, -, .

82 | III


, , .

HeadacheTest
, ,
,
.

..
[email protected]
, ,
,
() ():... ..
MEDIKO-SOCIAL ASPECTS OF PATIENTS PSORIASIS ARTHRITIS
Mishina E.S.
Kursk State Medical University, Russia, Kursk
The Faculty of Medical, Department of dermatovenerology
Scientific Adviser(s):Ph.D. Harahordina Y.E.
Keywords:psorias, psoriasis arthritis, mediko-social aspects
: , ,
Abstract:In article results are presented research of mediko-social
aspects patients of a psoriasis arthritis .Statistical data of a sex, age,
residence and disease terms by a psoriasis and psoriasis arthritis are
given.
:
.
2-7% *4+.

,
*1+.
*3+.
;
24-36% .

*2+.
:
-
-
.
: 20
(13 7 )
-
.
:
.

.
, 75%
25% .

30-39 (43%) 4049 (28%). 50-59
(54%).

:
.
.
:

.
.
:
1. (
) .

, .
2. ,


.
3. , ,
,
-
( - ).
:
1.
..
. . .,N 11,1997,.14-19.
2.
..
. . .N
7,1999,.23-27.
3
.. . .
.N7,2003,.81.
4
.. . . .1999,224 .

.., .., .., ..
[email protected]
, ,
,

() ():..., .
CORRELATION BETWEEN CLINICAL FORMS OF SHIZOPHRENIA IN
FAMILY
Pisaryuk A.S., Chernobylskay N.L., Shitikova A.D., Birukova M.G.
Peoples' Friendship University of Russia, Russia, Moscow
The Faculty of Medicine, Department of psychiatry and medical
psychology
Scientific Adviser(s):Candidate of medicine, associate professor
Artemeva M.
Keywords:inheritance of schizophrenia, clinical forms of split mind,
family illness
: ,
,
Abstract:The main object of this work is to find the connection between
clinically significant of schizophrenia in family. Fords theory had been
taken in base of this work. In fact we can suppose: if the mother who
suffer catatonic split mind have a sick child, his clinically significant will
be the same. We used next methods: questioning, sc. PANSS, database
formation and statistical processing of database, with program Statistic
6.0. The result of research can help with forecast of disease and genetic
counseling.
-


. (1960).
, ,


.
.
, , ,
, ,
, .
.
,

.
, ,
, .
, , , ,
,
, .., ,

 . , , , 2011 | 83
,
;
, ..
:
.
:
, PANSS,

6,0.
: 10 2

:

.
,
, ..
, ,
.
. ,
, ,
, , ;

.
,

,
.
:
I
: 4.1% - 13.8% -

; 3.9% - 13.7%
-
; 5.5% - 4.6% -

; 6.6% - 19.7% -

; 13.9% -
.


.
, ,

80 - 100%,

.
,


,
()
,

(

(60- ))

,

.
..
[email protected]
, ,
,
() ():..., . ..
ASSESSMENT OF QUALITY OF LIFE, SEVERITY AND THE EFFECTIVENESS
OF THERAPY WITH CONVENTIONAL TREATMENT IN PATIENTS WITH
ATOPIC DERMATITIS.
Pletnyova A.A.
Kursk State Medical University, Russia, Kursk

The Faculty of Medicine, Department of dermatovenerology

Scientific Adviser(s):M.D., prof. Silina L.V.

,
.
20
40%. .

,
, ,
,

, , ,
-
.

.
- SCORAD,
( ),

,
.
30 ,
: ,
, 17 45,
2-4 ,
,
.
,
.

.

:
(, /, , ,
, ) ( /
). SCORAD
, ,

.
0 3 .
,
( 1
1% ) 10

:
SCORAD=A/5+7B/2+C, A-
, B-
, C-
.
0 103. SCORAD
40
, 40 60 , >60-.
()


,
.
.
-30 , -0. ,
.
,
62,10%,
SCORAD- 81,1%.
35%, - 82%,
- 45% - 18%.
( 65%).

, ,
, 8 20 .
,

, ,

.

84 | III

..
[email protected]
,
, ,

() ():... .., ... ..
THE NEUROLOGIC STATUS OF PATIENTS WITH VARIOUS FORMS
PSORIASIS AGAINST TRADITIONAL THERAPY
Tishin A.N.
Kursk State Medical University, Kursk
Medical faculty,Department of neurology and neurosurgery,
Department of dermatology and venerology
Scientific Adviser(s):Ph.D. Laskov V.B., Ph.D. Silina L.V.
Keywords:the neurologic status, psoriasis, forms psoriasis, a vegetative
dystonia, neurologic infringements
: , , ,
,
Abstract:70 patients with various forms psoriasis have been surveyed.
The general features of the neurologic status are: brain symptoms, a
syndrome of vegetative dysfunction and sensomotor neuropathy. It is
characteristic: at psoriasis vulgaris - presence of brain symptoms, a
syndrome of a vegetative dystonia, sensitivity decrease; at psoriatic
arthritis - decrease knee and ankle reflexes; at erythrodermic psoriasis the expressed vegetative dysfunction and sensitivity decrease.
: ,

.
.
- 70
(43 27 ) 2009 -
2010 . 21 69 .
(53, .. 76%) 6 , 7
(10%) 21 .
,
3 : I -
(49
), II (12 ) III
(9 ).
.

(.., 1991)
( ).
: 72,9%
. ,
(85,7%) .

. 12 (17,1%)
. 37 (52,9%)
.
.

94,2% .

, ,
.
(
).

,
.
. 1. , ,

, ,

.
2.

:

, ,
-
,
,


.
3.
.
.

-
,
. .
[email protected]
, ,
,
() ():... . ..
CLINICAL AND PSYCHOLOGICAL FEATURES OF PATIENTS WITH
MODERATE ACNE
Chukova N. A.
Kursk State Medical University, Russia, Kursk
The faculty of Medicine, Department of dermayovenerology
Scientific Adviser(s):MD Prof. Silina S.V.

, ,

.

, , , .
-
,
.
25 18
30 , ,
2- 10 .

,
, ,
,
.

(, , , -, ),

( ).
, ,
,
. ,
,
, ,
.
,
,

,
.

(
.)
..
[email protected]

 . , , , 2011 | 85

, ,
,

() (): ..
THE ORGANIZATION EMERGENCY CARDIOSURGERY THE HELP TO
PATIENTS WITH A SHARP HEART ATTACK OF A MYOCARDIUM (ON AN
EXAMPLE OF KALUGA)
Belozor E.A.
GOU VP the Russian state medical university Roszdrava, Russia,
Moscow
Medical faculty, chair of public health and public health services
Scientific Adviser(s):Senior lecturer Tolchyonova E.A.
Keywords:Cardiovascular pathology, heart surgery, hi-tech operations,
myocardium heart attack, rombembolia a pulmonary artery, financing
: - ,,
, ,
,
Abstract:The Cardiovascular pathology is in the lead in death rate and
physical inability structure. Research objective: perfection of an
emergency heart surgery. The quantity the operated patients annually
increases, the postoperative lethality decreases. Modern technologies
(coronarographia, installation stents, plasticity of arteries cylinder ,
filters of vessels, pacemakers) are introduced. At worthy level of a heart
surgery its perfection is required.
-
.

.
: .
:
. .
:

(2007 . 89; 2008 . 174; 2009 . 178).
(2008 . 792; 2009 . - 772)
(2007 . 0,3 %; 2008 . 1,1%;
2009 . 1,4%)
(2008 . 1,1%; 2009 . 0,6%)
(: 2004 . 226,
2006 . 395; ,
: 2004 . 40; 2006 . 80;
: 2004 . - 34, 2006 . - 15; :
2004 . - 0 , 2006 . 14; : 2004 . 1;
2006 . - 1)
:

; - ;
;
.
,
,

-

18-20 . , 15
30 , .

.., .., ..
[email protected]
, ,
,

() (): ..., . ..

RESULTS OF PSYCHOLOGICAL EXAMINATION AND TREATMENT OF

PATIENTS WITH A PSYCHOGENIC SKIN ITCH
Atayan N.K., Marilov V.V., Artemieva M.S.
Peoples' Friendship University of Russia, Russia, Moscow
The Faculty of Medicine, Department of psychiatry and medical
psychology
Scientific Adviser(s): M.D., professor Marilov V.V.
Keywords: psychogenic skin itch, neurosises, depression, alarm
: , , ,

Abstract. At treatment of patients with neurosises the skin itch which

has been not connected with a somatic pathology quite often comes to
light. At psychological examination at such patients high indicators on
alarm and depression scales are revealed. At treatment it is disturbingdepressions accompanied by a skin itch, efficiency of application of
energizers (Fluvoxamine) and neuroleptics (Aethaperazinum,
Quetiapine) is high that proves to be true by psychological research and
disease clinic.
,
.

- ,
, ,
.
:
.
: 8 . ..

18 18 65 (3 , 15
). 35% - F45, 30%
- F41, 20% - F32, 15% - F06.
35 .
,
, ,
-.
:
, ,
, ,
(, , , , ).
.

(HDRS > 20, HARS > 20).
: ,
,
,
,
,
.

: , ,
, (,
, -). .
.
, 80%
(F32,
F45, F41). 20% ( 60 )
(F32, F06).
( 100 /,
10 /, 450 /)
(< 10 HARS), ,


.
:
,
.

. - ,
,
()
(, ),
.

86 | III


.., ..
[email protected]
, ,
,
() (): ... ..
DIFFERENTIAL DIAGNOSTIC OF VASCULAR DEMENTIA AND
ALZHEIMER'S DISEASE
Basova E.A., Manyakin I.S.
People's Friendship University of Russia, Russia, Moscow
The Faculty of Medicine, Department of general doctor's practice and
family medicine
Scientific Adviser(s): Ph.D. Kobylianu G.N.
Keywords: Differential diagnostic, vascular dementia, alzheimer disease,
the Hachinsky ischemic scale, cognitive impairment, hypertension,
atherosclerosis
: ,
, , ,
, , .
Abstract: The Hachinsky ischemic scale, based on clear clinical signs, is
used for differential diagnostics of vascular dementia and Alzheimer
disease. Vascular dementia may be diagnosed when patient gets a score
of 7 or higher on this scale. The most important criteria are abrupt
onset, stepwise progression, history of hypertension, strokes and focal
neurological symptoms. A score of 4 or less suggests Alzheimer disease.
The correct diagnostics helps to choose the necessary treatment, which
is nevertheless only palliative.
()
,
.
,
, ,

,
:
1.
(,
).
2.
, ,
: , , ,
,
.
3.
,
.
4.

.

, 90%
, (,
).
.
, ,
.

,
.

1.
(2 )
2.
(1 )
3.
(2 )
4.
(1 )
5.
(1 )
6.
(1 )
7.
(1 )
8.
(1 )
9.
(
) (1 )
10.
(2 )
11.
() (1 )
12.
(2 )

13.
(2 )
, ,
,
,
(7 ) .
4 ,
,

.
.
: 3-10%;
- 15-30% ( 40% );
; - ,
;
,

; - ; - ,
, .
: 65-85 5%,
85 15-25%; 5060%; ;
; -
, , , ,

(); -
, ;
- .
, ,
() ().
(,
), .

().

70-500
.
()
,
.


.

(
)
. . , . . , . .
[email protected]
, ,
,
() (): ... ..
ON THE SIZE OF THYMUS OF CHILDREN AND ADOLESCENTS (
ACCORDING TO THE DATA OF THE ULTRASOUND STUDY)
Z. V. Smyslova, N.N. Ryakhina, O.A. Osadchaya
Peoples' Friendship University of Russia, Russia, Moscow
The Faculty of Medicine
Scientific Adviser(s): Ph.D.L.G. Kuzmenko
Keywords: thymus, size of thymus, children
: , ,
Abstract. Target: to detect the reference values of the mass of thymus of
children and adolescents between 2 and 17 years old. The mass of
thymus of 112 children and adolescents 2 16 years old was detected
within the intermorbid period according to the technique of S.M.
Voevodin (1989) by the method of ultrasound study using thecurved
array transducer of 5 MHz. Chidren and adolescents having taken partin
the study were pratin the study were practicale healthy, had no genetic,
endocrine, nervous diseases. The processing of the achieved results was
carried out using the method of variation statistics. The average mass
of thymus ( ) was statistically different ( < 0,05) and equaled for

 . , , , 2011 | 87
the children 2 5 years old 21,9 8,9, for the children 6 10 years old
18,0 7,9, for the adolescents 15 16 years old 9,1 1,9. Conclusion:
the mass of thymus decreases as the age of children increases.
( ),

. 20
,
.

()
(.. ., 2007; ..
., 2007) 24
(.. ., 2002).

2 16 .
. 112
2 16 ( 25 64, 614
43, 1516 5),
.. (1989).
.. (1994).
Aloka-630
5 .
:
,

1,5 . :
,
, ,
,
2 .

(),
(), (m).
.
. ( )
2 5 21,9 8,9 (m=1,1), 6 10 18,0
7,9 (m=1,1), 15 16 9,1 1,9 (m=1,1).
( < 0,05).
:
.

, .

about CRP as a risk factor for cardiovascular diseases in group of

patients with type 2 diabetes.
: - -
(-hs) 2 (-2).
.
50 -2, 14 36 .
52,14,2 .
7,63,6 .
, 1999 . 64 %
(17%), 36
%
(1<7%).
-hs
, 1
(PAI-1)
ELISA, (, , , , )
ImmunochemistrySystems,

,
.

STATISTICA-6,
.
. -2


-hs (=0,05),
16,532,1 /. ,

-hs

(r=0,55,
<0,005), (r=0,49, <0,005), - (r=0,42,<0,005).


, (r=0,35, <0,005) (r=0,31,
<0,005), PAI-1 (r=0,49, <0,005).
: 2
-hs
, ,
, ,
-
.

- 2
.., ..
[email protected]

, ,
,

() (): ... ..

,

..
[email protected]
, ,

,
() ():
() (): ... ..

C-REACTIVE PROTEIN AS A CARDIOVASCULAR HIGH RISK FAKTOR IN

PATIENTS WITH TYPE 2 DIABETES
Isakova D.N., Salahova E.I.
Tyumen State Medical Academy, Russia, Tyumen
Medical Faculty, Department of hospital therapy with course of
endocrinology
Scientific Adviser(s): Ph.D. Dorodneva E.F.

INFLUENCE OF DURATION OF ARTIFICIAL BLOOD CIRCULATION ON

NEUROLOGICAL STATUS IN PATIENTS UNDERGOING CORONARY
ARTERY BYPASS SURGERY
Kolmykova J.A.
The Kemerovo state medical academy, Russia, Kemerovo
The faculty of medicine, department of neurology
Scientific Adviser(s): Ph.D. Kovalenko A.V.

Kekywords: C-reactive protein, type 2 diabetes mellitus, cardiovascular

high risk factor
: - , 2 ,
-

Keywords: artificial blood circulation, neurological status, coronary

artery bypass surgery
: ,
,

Abstract. Result of the research showed that C-reactive protein (CRP)

level is significantly increas in group of patients with type 2 diabetes
with decompensation of a carbohydrate metabolism. CRP positively
correlates with some cardiovascular risk factors. This allows to speak

Abstract: To assess and compare the dynamics of neurological status in

patients a two days after coronary bypass surgery

,

88 | III
,
.
: 45
, ,
,
55,204,73 . 2
( 90
90 ).
,
.
,
:
- (), -
()
,

Status-PF
(, .., 2001). , 2-3
10- .
statistica 6.
:
: - 1 (2,3%), - 18
(40%), 10 (22,2%) - 16
(35,5%). 2-
(100%)
;
90
- , ,
90
(=0,05). 10- ,

90 90 (=0,03).

, ,
90 2-
,
,
90 (=0,008),
(=0,005), (=0,005),
(=0,04), (0,04). (MMSE, FAB,
, )
2-3 , 10 .
:
,
;

2-3 ,
.
10
. (MMSE, FAB, ,
)
.

.., . .
[email protected]
, ,
,
() (): ... ..
HYPERTENSION AS THE CAUSE OF VASCULAR ENCEPHALOPATHY'S
PROGRESSION
Manyakin I.S., Basova E.A.
People's Friendship University of Russia, Russia, Moscow
The Faculty of Medicine, Department of general doctor's practice and
family medicine
Scientific Adviser(s): Ph.D. Kobylianu G.N.
Keywords: Vascular encephalopathy, hypertension, atherosclerosis,
ischemic stroke, hemorrhagic stroke, chronic cerebrovascular disorders,
grades of cognitive impairment.

: C ,
, , ,
, ,
.
Abstract. Target organ impairment in hypertension involves cerebral
damage, including acute ischemic and hemorrhagic strokes, as well as
chronic cerebrovascular disorders. Among hypertensive patients without
history of stroke cognitive impairment (vascular encephalopathy) can
also be observed, not only in elderly age, but in middle age too. The
damage of cerebral arteries and arterioles is provoked by
atherosclerosis and/or hemorheological that lead to vascular
encephalopathy.

()

.
,
, ,

. -
, (
),
.
, , , .

.


,
, ( 35 40 ). ,
, ,
,

.

(),
.

,
,
.
,
, ,

..

, .
()
:
1.

( - /
; ; ;
: , ,
..).
2.
;
3.

.
/
,

.
(
), , ,
,
.

( ).
,

,
. ..
(2005) ,
.
, ,
- ,

 . , , , 2011 | 89
(
) .
,
.
1.

, , ,
, -.
2.

, ,
(, ).
3.

.

.

..
[email protected]

, ,

"
" ()
():
..., . ..
APPLICATION OF ELASTOGRAPHY FOR DETERMINING THE
MANIFESTATION OF FIBROSIS AND ITS COMPLICATIONS WITH THE
ALCOHOLIC LIVER DISEASE
Morozova T.G.
Smolensk State Medical Academy, Russia, Smolensk
Department of faculty therapy, (PSC) "Ultrasonic studies and
miniinvasivetechnologies"
Scientific Adviser(s): A.V.Borsukov
Keywords: alcoholic liver disease, ultrasound elastography of the liver
and spleen, fibrosis
: ,
,
Abstract. The carried out the estimation of possibility and the
substantiation of the application of elastography in patients with the
alcoholic liver disease (ALD). According to the results of a study one
should use elastography of the liver and spleen as the additional
criterion of diagnostics of the development of complications of ALD, and
also for monitoring of treatment. Elastography of spleen increases the
accuracy of diagnostics of ALD both at the stage of severe fibrosis and
with the light degree.

, ,
.

,


,

.


.

-
,
.
.


.

, 2010 2011 .
37 (20 17
19 55 ),
.
: 10,
15, 12 .

Hitachi 525,
.
FibroScan (Echosens,
) .
METAVIR 0 4. 31
, G16-18,
.
.

29 ,
29 .


.

.
, 4
F1-F2-F3, ,
F4.
,
,
. ,


.
. 1.
,
, , ,
,
.
2.
,
, ;

.., ..
[email protected]
- . . .
, ,

() (): ... ..
HEART RHYTHM DISTURBANCE IN PATIENTS WITH PAROXYSMAL
ATRIAL FIBRILLATION IN INTERICTAL INTERVAL
Orudzhev F.K., Bzhinava K.M.
Bakoulev Center for Cardiovascular Surgery
Russian Academy of Medical Sciences, Russia, Moscow
ardiology
Scientific Adviser(s): Ph.D. Tembotova Z.K.
Keywords: paroxysmal, atrial, fibrillation, heart, rhythm, disturbance,
interictal, interval
: , , ,
, , , , ,

Abstract. During the research was studied 12 patients with paroxysmal

atrial fibrillation, with frequency of paroxysmal episodes more than 1 in

90 | III
3 month. It was used 72-hour Holter recording and then analyzed V5,
V1 and Y ecg leads. As a consequence was discovered, that Atrial
extrasystoles (incipient, aberrant and blocked) are leading heart rhythm
disorders in patients with paroxysmal idiopathic atrial fibrillation in
interictal interval.
: ,


.
: 12 : 10
401,3 2 48
4,6 ,
3 ,
. 72
-4 . . 3 : V5, V1
Y.
Statistika.
: 12 72
62 3897
(784,4 95,9). : 12 1244
(442,1 94,7), ( )- 23 564 (346,582.5),
11 945 (4578,3) , 4 118
(78,93,5), 5
13 189 (41,51,2), 10
1 . 5

( ?)
3 18 ,
, 3 43
(15,70,5),

.
:



, ,
, , -,


.

. .
[email protected]
. . .
, ,
-
() (): ... ..
STATE OF THE CARDIORESPIRATORY SYSTEM IN OBESITY
Pshennova V.S.
The Russian State Medical University, Russia, Moscow
Medicobiologic faculty
Scientific Adviser(s): MD Alexandrov O.V.
Keywords: Obesity, respiratory function, histology, pulmonary artery
pressure
: , , ,

Abstract: The aim is to study the state of the cardiorespiratory system in
obesity. Methods: pneumotachography, echocardiography, microscopic
of the respiratory muscles. The males with III degree of obesity showed
a high correlation between anthropometrical rates and ventilation rates
(p=0,04). The mean pulmonary artery pressure in the males in the study
group was higher than the normal rates (p=0,05). The degree and type
of obesity impact on the progressive deterioration of pulmonary
function rates.

It is of interest to find out if the causes of dysfunction of the respiratory

system are a consequence of obesity or they arise against a background
of cardiovascular pathology that is very common in obesity.
The aim is to study the state of the cardiorespiratory system in patients
with various degrees of obesity.
Objectives:
- To study lung ventilation function according to the degree and type of
obesity;
- To evaluate change in pressure in the pulmonary artery according to
the degree and type of obesity;
- To evaluate the morphological condition of the respiratory muscles in
patients with obesity.
Methods:
1. Pneumotachography;
2. Echocardiography;
3. Microscopic of the structure of the diaphragm and the intercostal
muscles.
80 non-smoking patients aged 21 to 76 years (56 females and 24 males)
with I degree of obesity (24 persons), with II degree of obesity (16
persons) and with III degree of obesity (40 persons) without pathology
of the respiratory system were examined in the study group. The control
group included 20 healthy non-smoking persons aged 20 through 75
years (13 females and 7 males.
Results: In the study group, 41% of patients had disturbances in lung
ventilation function (19% of obstructive nature, 9% of restrictive nature,
14% of mixed nature). The lowest rates were found among the males
with III degree of obesity (the volume rates were on average moderately
reduced compared to the norm), and their VC, FVC, FEV1 and PEF were
significantly lower than those of the males in the control group were.
The study group showed moderate-to-middle inverse correlations
between anthropometrical rates (body mass index, the waistline, the
waist-hip ratio) and ventilation rates. Pulmonary function rates were
most sensitive to the waistline and the waist-hip ratio, and the
correlation level among the males was significantly higher than that
among the females was. The males with III degree of obesity showed a
high correlation between the waistline, FVC and MEF 50 (0,8 and 0,75,
respectively), and between the waist-hip ratio, FEV1 and FEF 25-75 (0,64
and 0,71, respectively). Moreover, there were seen high correlation
rates between the waistline and pulmonary function rates among the
males, as well as between the waist-hip ratio and ventilation rates
among the males and females.
In addition to the studies of the functional state of the respiratory
system, diaphragm and intercostal muscles biopsies were obtained in 10
patients. In all 10 cases, the underlying pathological changes in muscle
tissue were expressed in myofibril dissociation and the disappearance of
cross striation, in the thinning and destruction of individual fibers with
the substitution of tissue fragments for fat cells. It also lead to a
decrease in the contractile function of the respiratory muscles. 40
patients in the study group (50%) underwent echocardiography. The
studies showed the following: although the mean pulmonary artery
pressure in the study group did not exceed the normal rates (19 mm Hg)
but it was significantly higher than in the control group (15 mm Hg). The
mean pulmonary artery pressure in the males in the study group was
higher than in the females (21 mm Hg and 18.5 mm Hg, respectively)
and it exceeded the normal rates (p=0,05).
Conclusions: The studies show that obesity significantly reduces
pulmonary function rates. The intensity of ventilation rate disturbances
depends on the degree of obesity, over and above the most evident
disturbances are associated with abdominal-type obesity. One can
definitely say about the impact of the degree of obesity on the
progressive deterioration of pulmonary function rates. One can also say
with a high degree of confidence that obesity (especially abdominal-type
obesity) affects the increase of the pressure in the pulmonary artery
(development of the pulmonary hypertension), which is an additional
factor in lung function reduction.

-
.., ..
[email protected]

 . , , , 2011 | 91
() (): ... ..
DIAGNOSTIC VALUE OF DISPERSION MAPPING FOR SCREENING OF
CARDIO - VASCULAR PATHOLOGY
Ryazanova Y.V.,Chernoglazov K.S.
Kuban State Medical University, Russia, Krasnodar
Department of the policlinic therapy
Scientific Adviser(s): Gorban V.V.
Keywords: dispersive mapping, Cardiovisor, myocardium
: , "",

Abstract: Cardiovisor is a method of screening - diagnostics of functional

state of the heart. This method is based on the principle of 3-D
visualization of electromagnetic radiation of the heart muscle and
computer analysis of data obtained. Results of the survey 315 people
were given. This method can detect pathological disturbances in the
heart at early stages of the development.
:

- .
.
(-06) 315 (235 80
) 49,50,7 ,
.
(1030
) () ,

() .

,
,

(),
, - .
.
.
3 : 1 (145 )
15% ( ); 2 (126
) - 16-26% ( ); 3
(44 ) 27% (
).
42,04,1% 1- 11,34,7% 3-
( < 0,05). 1- (
14,00,2%, 28,01,3%) 32
(21,33,4%) () 9
(6,22,0%) ( > 140/ .
.) ( 5,0 /),
() .
2- ( 19,00,2%;
391,8%)
,
1- (40,44,4% 11,12,8% 21,33,4% 6,22,0%,
, < 0,05), 5 (3,91,7%),
6 (4,71,9%). 3- (
37,01,1%, 45,03,5%)

, 2- ,
1- (38,67,3% 22,76,3% 21,33,4% 6,22,0%,
, < 0,05). 3- (9,04,3%) 2-
, ( 13,65,2% )
2- (3,91,7% 4,71,9,
, < 0,05).
:
,
(74%)
(78%), (58,9%)

.


.

.., ..
[email protected]


() (): ... ..
THE ANALYSIS OF THE REGISTER OF PATIENTS WITH ACROMEGALY IN
IRKUTSK REGION
Safronova K.I., Rudih I.V.
Irkutsk State Medical University
Department of endocrinology and clinical pharmacology
Scientific Adviser(s): Dr. Shagun O.V.
Keywords: acromegaly, somatoprolactinoma, adenoma
: , ,

Abstract: The aim of the investigation: to study the structure,

specificities of the course of the disease and approaches to the
treatment of acromegaly in Irkutsk region. The methods of investigation:
the structure, specificities of the course of the disease and the
approaches to the treatment of acromegaly were studied by means of
the analysis of the acromegaly patients register in Irkutsk region
(December, 2010).
: ,
.
: ,

( 2010 ).
. 72
17 (23,6%) 55 (76,4%) .

55,612,3 ( 19 75 ).
55,59,3 ( 32 66 ), 55,113,2 ( 19 75
), =0,1. 39
(54,2%) , 20
(27,8%) , 13
(18%) . ,
14 (82,3%), 25
(45,4%), =0,02. 2 (11,8%)
18 (32,7%) , = 0,2. ,
, 1 (5,9%) 12 (21,8%) , =0,2. 7 (9,7%)

(): 5 (9,3%) 2
(11,8%) , =0,3.

. , (
) 67 (93,1%) , 16 (94,1%) 51
(92,7%) , =1,0; 57
(79,2%), 14 (82,3 %) 43 (78,2 %) , p=0,4.
43 (59,7%)
, 8 (47%) 35 (63,6%) , =0,8.
37 (51,4%) , 29 (52,7%)
8 (47 %) , =0,9.
39 (54,2%) , 9 (53%) 30
(54,5%) , =0,8. 12 (16,7%)
(8 ), - 3 (17,6 %) 9
(16,7 %) , p=1,0; 20 (27,8%),
6 (35,3 %) 14 (26 %) .
16,516
(3,2-31,4) /, 8,310,2 (1,62-13,7) /, =0,06.
-1 (-1) 23
(32,4 %) , 4 (23,5 %) 20 (36,4%) .
-1 438,7112,6 (368-600) /,
- 355203,4 (203,5-529,5) /, =0,06.
25 75 . , 19
(26,4%) .
26 (36,1%), 6 (8,3%)
. 13 (18,1%)
. (

92 | III
)
8 (11,1%) . , 2005 2010
. , ,

62 (86,1 %).
20 (28,2%). (4,2%)

( ).
.
.
37,5%
.

.., ..
[email protected]
.
. , ,
,
() (): ... ..
ANALYSIS OF COMMITMENT TO TREATMENT OF VARIOUS CATEGORIES
OF PATIENTS WITH HYPERTENSION
Sergeyeva V.A., Glukhova O.E.
Saratov State Medical University of V.I. Razumovskiy, Russia, Saratov
The Medical Faculty, Department of Hospital Therapy
Scientific Adviser(s): Ph.D Sergeyeva V.A.
Keywords: Hypertension, antihypertensive therapy, commitment
: ,
,
Abstract. In general the commitment to antihypertensive therapy
remains on insufficient rate. Women are more committed to
antihypertensive therapy than men. Patients in small towns of the
region also are more committed to antihypertensive therapy than in
Saratov. The main factors of intermittent reception are the low
compliance of a physicians and wellness during high blood pressure.

()
,

().

. , ,
,
,
.
:
.
: 90 .

,
, .
.
12 ,
8 11 , 8 .
: ,
9,60,7 ,
5,10,8 , ,
,
.

(48,9% ).
:
47,7%,
18,2%.

, I
(10,2 0,8 ),
III (10,9 0,5 ); II
(11,51
), ,
.

(11,80,5 )
(<0,05) (8,90,6 ).
,
,
10,50,5,
12,00,7 (<0,05).

:
, 12,10,6 , 10,20,7
.
: ,
, ,

.
,
.
,
,
, , ;
,
,
;

. ,

,
, ,

.

.., ..
[email protected]
.
.
,
() (): ... ..
COMMITMENT OF ANTIHYPERTENSIVE THERAPY IN PATIENTS WITH
HYPERTENSION AND DIABETES MELLITUS
Sergeyeva V.A., Magomedova H.M.
Saratov State Medical University of V.I. Razumovskiy, Russia, Saratov
The Medical Faculty, Department of Hospital Therapy
Scientific Adviser(s): Ph.D Sergeyeva V.A.
Keywords: Commitment, hypertension, diabetes mellitus
: , ,

Abstract. The commitment of antihypertensive therapy in patients with
hypertension and diabetes mellitus remains relatively low. Commitment
of antihypertensive therapy increases in groups of patients with III stage
of hypertension and with longer period of insulinotherapy.
()
(),
- ,

.
()

.
:
.

 . , , , 2011 | 93
: 100
2 (- ),
.
. 57,11,6 .
12,61,4, 10,01,05. II - 69%, III
31%.
, 21 .
12
, 8 11 , 8 - .
: 43%
, - 51%
6% .

39%

. ,
: - 41%,
- 20%;
- 14%; -10%;
- 10%, - 5%.

12,40,3 ; - 12,80,5
, - 12,00,4 .

, II
12,00,3 , III
(<0,05), 13,80,4 .

. 3
:
( ),
- 5 ,
5 .

5 (12,80,5 ),
5 (12,30,5
)
(11,060,4 ).
:
.
,


.
III ,
,
.

[
. ]

[C]
[DENTISTRY]

 . , , , 2011 | 95
COMPARATIVE CLINICAL TRIAL OF MULTIPLEX GINGIVAL RECESSION
TREATMENT METHODS
Andrs Szura, Laura Flumbort
University of Semmelweis, Faculty of Dentistry, Clinic of Parodontology
Supervisor: Blint Molnr DMD University of Semmelweis, Clinic of
Parodontology
Introduction, Aim: According to literature data, the Coronally Advanced
Modified Tunnel-technique (CAMT) is a predictable method for
multiplex gingival recession surgical treatment in Miller I-II type defects.
We followed-up this kind of surgical treatment and wanted to know
what type of healing is available 6 months after with two different
accessory materials.
Materials and Methods: We followed up the healing in 20 patients with
multiple symmetric gingival recessions. The following methods were
used in two groups of patients: I: CAMT+Subepithelial Connective Tissue
Graft (SCTG) II: CAMT+ resorbable xenograft membrane (Mucograft).
The following clinical parameters were registered: gingival recession
depth, gingival recession width, papilla contact point distance, papilla
width, parodontal probing depth, keratinized gingival width and
thickness. These parameters were measured before and 1, 3, 6 months
after the surgery.
Results: 6 months after surgery the results in cover of the gingival
recession and the keratinized gingival width were better in CAMT+SCTG
group than in CAMT+Mucograft group, but there was no statistically
significant difference.
Conclusions: Both of the examined accessory materials can be
successfully used with CAMT-technique. 6 months results were better in
CAMT+SCTG group, but no statistic significance was found. The surgical
procedure of CAMT+Mucograft group was shorter in time and the
patients had less postoperative complaints after this treatment. So we
can declare, that the Mucograft is a successful alternative for SCTG
combined with CAMT. With use of Mucograft we can make the CAMT
procedure shorter, and decrease the patients morbidity.

.
.. , .. , .. , .
[email protected]
, ,
,
.
:... .. , .. ,
.. ,
STERILIZATION AND DISINFECTION OF EXTRACTED TEETH
Burschalli S.N. , Baykulova M.D. , Sarieva E.S. , Nurueva N.N.
Peoples' Friendship University of Russia, Russia, Moscow
The Faculty of Medicine, Department of stomatology
Scientific Advisers:Dr. Bulgakov V.S., Vereskova M.A, Shapovalova S.V.,
Potylico G.A.

1) 12- .
2) :
)
)
,
(
).
3) .

120 50-60
, .
4) ,
, .
.
5) 37
6):
) :
-300 ( (2 ) -
, (1 ) - )

, . .
( ) ,
(
) .
) :
) :
:
-300
.
:

.
,
, 20 % ,
70 % ,

,

..
[email protected]
, ,
,

:. ..
HYGIENIC ASSESSMENT OF ORAL HEALTH OF CHILDREN LIVING IN AN
ORPHANAGE ASENEVSKOE
Arzumanyan A.G.
Peoples' Friendship University of Russia, Russia, Moscow
The Faculty of Medicine, Department of Dentistry of childhood with a
course of orthodontics
Scientific Adviser:Prof. Kosyreva T.F.

Keywords: Sterilization, disinfection, teeth, action, means, efficiency,

phantom, students, processing, research
:, , , , ,
, , , ,
Keywords:hygienic condition of the oral cavity of children's home, the
prevalence and intensity of caries
:
:
.
,
:

Abstract: The study of the dental health of children Asenevskoe
.
orphanage showed a low level of oral hygiene, a high prevalence (94.1%)

and intensity of dental caries (5,0). Hygienic condition of the oral cavity

rated as poor (average 2.9). Most of them are not provided dental care.

-
,

,
.
.
: , , ,
,

. 17 .
:
4 18 . : 52,9% (9 .)
1.
, 47,1% (8 .) .
.

.
2.
, 5,9%

96 | III
( ,
),
5,9% .
94,1% ( 56,25%
, 43,75% )
(81-100%).
100%, 87,5%.
,
25% (19% , 6% ),

75% (6 (35,2%) 4 15 ,
6 (35,2%) 11 16),
.
,
6,25% .
56% 3 ,
31% - 4 10 , 12% - 10 .
,
,
(.. )
70,6%;
( ,
, ) 23,5%;
, 5,9%. ,
,
( )
, ,
, ,
.
.
80 ( 62
12 1;
18 4 0),
5,0
, >0
( 16 .). =5,0

.
,
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.

( 2,9).

(41,2%),
(5,9%)
(5,9%).

.., .., ..
[email protected]
, ,
,

: ..
AVERAGE ANATOMICAL TOOTH DIMENSIONS.
Garifullina R.F., Dadiomov M.A., Sharyafetdinov R.D.
Peoples' Friendship University of Russia, Russia, Moskow
The Faculty of Medicine, Departament of propaedeutics of stomatologic
diseases
Scientific Adviser: professor Bulgakov V.S.
Keywords: enamel, dentin, pulp, cuts and sizes of teeth, incisors,
canines, premolars, molars
:, , , ,
, , ,
. 1) ,
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x=a/b, a - ,
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 . , , , 2011 | 97
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(1,810,45).
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(0,230,09), .. (0,260,14).
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6) .
.
,
.
. ,
,
,
."

.
..
[email protected]

, ,
,
:..., ..
TENDENCIES IN CHANGE OF APPROACHES TO TREATMENT OF
STOMATOLOGIC COMPLICATIONS AT PATIENTS WITH DISEASES OF
SYSTEM OF BLOOD ON THE BASIS OF LITERARY GIVEN AND OWN
SUPERVISION.
Gvozdicova Y.
People's Friendship University of Russia, Moscow
The Faculty of Medicine, Department of General Dentistry
Scientific Adviser: Ph. D. Avanesov A.M.
Keywords: Blood diseases, ulcerative necrotic lesion of oral cavity
: ,
Abstract: The first message on oral cavity defeats at sharp leucosis
belongs Ebstein. Later many researchers specified in similarity of
changes in an oral cavity at leucosis with the heavy form scorbut.Thus
any surgical interventions at the given category of patients at the given
stage of development of hematology were called into question in the
absence of possibility to spend corresponding transfusion preparation.
But in 1986 A.M.Avanesov has shown, that indications to surgical
treatment at patients leucosis are all kinds the tooth inflammatory
processes and their complications.Till today the hematology actively
develops also successes in the field of diagnostics and treatment
hemablastosis have allowed increasing quantity and duration of
remissions, to make real recover

Ebstein (1889). , ,
, ,
, : ,
, , .

:
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,- ,
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( .. ,1945;
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, 1989 . .

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98 | III

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(Demarosi F., 2002).
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1975 .),
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2009 2011

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(27),
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-
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CEREC 3
.., ..
[email protected]
-
, ,
,

:... ..

COMPARISON ANALYSIS OF WORKING PROCEDURES FOR

MANUFACTURING RESTORATION WITH PRECISION MARGINAL FITTING
USING CEREC 3
Generalov I.M., Goryainova K.E.
The Moscow State University of Medicine and Dentistry, Russia, Moscow
The Faculty of Medicine, Department of hospital orthopedic dentistry
Scientific Adviser: Ph.D. Retinskaya M.V.
Keywords:CAD/CAM, CEREC, CEREC Optispray, VITABLOCS Mark II, die
stone, Diamond Die, marginal fitting
: , CEREC 3,
, , , c
Abstract: We have studied in a comparison aspect acceptable marginal
fitting of restoration to a tooth using different working procedures: with
CEREC Optispray, CEREC Powder and special die stone. Results were
statistically compared using a point system. Conclusion: sample
manufactured using CEREC Optispray received the most points because
of less errors during the creation process.


()
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Powder (VITA Zahnfabrik, ), CEREC Optispray

 . , , , 2011 | 99
(Sirona, ).
,
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4.

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50 .
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.., ..
[email protected]

,
() (): . . . .., ...
..
APPLICATION OF ACTIVATED LOW-INTENSITY LASER RADIATION OF 3%
SODIUM HYPOCHLORITE SOLUTION AND GEL CONTAINING 15% EDTA
IN ENDODONTICS IN THE EXPERIMENT
Zaikova K., Britova A.
Yaroslav-the-Wise Novgorod State University (NovSU), Rossiya, Veliky
Novgorod
Faculty of Dentistry, Stomatology chair
Scientific Adviser(s): Ph. D. Britova A.A., Ph. D. Proshyna L.G.
Keywords: Teeth, the root channel, dentine, solution, hypochlorit
natriya sodium, liquid ED, simultaneously, to expand.
: , , , ,
, , , .
Abstract: The success of the treatment of patients with
pulpoperiodontalnoy pathology depends on the quality of endodontic
stages. Chemicals facilitate mechanical work abrasive tools. Sodium
hypochlorite solution has a proteolytic effect, dissolves the organic
structure of dentin root canal. EDTA decalcifying the dentin. Of interest
to study low-intensity laser light as an activator solution for irrigation
canals.
.
.

.
,
. .

.
. 3%
, -, 15% ,

.
.

28 35 . 3%
Parcan (Septodont), -
RC-Prep (PREMIER, ). 8
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0,01 ,
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100 | III
0.05 NaCIO. 3 -
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2 3

.., .., .., ..,
.., .., ..
[email protected]

,
,

: ... ..
ESTIMATION OF THE DENTAL EXAMINATION AT STUDENTS OF 2 AND 3
COURSES OF NIZHNIY NOVGOROD STATE MEDICAL ACADEMY AT THE
DENTAL FACULTY
azarina L.N., Vdovina L.V., Kondyurova E.V., Pursanova A.E.., Ellaryan
L.K., Davidkina E.A., Suhodol'skiy L.B.
Nizhniy Novgorod State Medical Academy, Russia, Nizhniy Novgorod
The Dental Faculty, Department of propedeutical Dentistry
Scientific Adviser: Ph.D. Kazarina L.N.
Keywords: student, dental examination, caries, prevalence, intensity
: , , ,
,
"SUMMURY

Abstract: The studying is devoted to actual topic of dentistry condition

of health in oral cavity at students of Dental faculty. High prevalence and
intensity of dental caries, also inflammatory periodontal diseases are
established. Necessity of treatment and prophylactic measures on
strengthening of oral health of learning youth is proved.
.
*1; 3; 4+.

-
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,
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,
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: 95 2- (67
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StatSoft ( 6.0).
.
:
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, 7,790,698. 3
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2 : 10,8061,374% , 12,572,547% ; 3
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3 .
:


.
:
1.
.., ..
.
.
2006; 2(19): 57-59.
2.
..
. . . . . . 1995; 2: 236.
3.
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.
, . 2003; 53-55.

 . , , , 2011 | 101
4.

..,

..

. ; 2006; . 415.
5.
.. :
/ .. . - .: Hyp. Med. Ltd.,
1993. . 332.

.., .., ., ..
[email protected]

, ,
,
: ,

PROPERTIES OF A SALIVA AT ITS INTERACTION WITH THE WATER
ACTIVATED BY PHYSICAL FACTORS
Kolegova T., Zaikova K., Svintsova M., Britova A.
Yaroslav-the-Wise Novgorod State University (NovSU), Russia, Veliky
Novgorod
Faculty of Dentistry, Stomatology chair
Scientific Adviser:Doctor of medical sciences, professor Britova A.

Keywords: Saliva, water, laser radiation, ultrasound, activation, crystals

: , , , ,
,
Abstract: Water changes structure at influence for it of physical factors
depending on an influence kind. Water is capable to transfer the
information on influence on a biological liquid. The method of a
crystallography of a saliva is capable to visualize character of influence
and its duration, ""memory"". Influence of ultrasound, low intensive
laser radiation and their combination on formation of crystals in a saliva
Activated by ultrasonic or low intensive laser radiation water promotes
formation of crystals in a saliva. Changes remain till 10 days and more,
increase of effect of formation of crystals with increase in a period of
storage is thus observed. There is a possibility to prepare medicinal
solutions on activated by laser and ultrasonic radiation to water. Direct
influence of physical factors on an organism is excluded.

, , .

.


.
,
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,
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.

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.
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,
. ,
,
. ,
,

.

,
10
. ,
,
.
.

..
[email protected]
, ,
"- ""
... ..,

PREVENTION OF DENTAL DISEASE OF DENTAL HARD TISSUES IN
CHILDREN AND TEENAGERS
Kulikova A.I.
Peoples' Friendship University of Russia, Russia, Moscow
"The Medic" Medic and Biology School
Scientific Adviser: V.V. Safroshkina, M.D., Associate Professor, Pediatric
Dentistry Department, People's Friendship University (Moscow, Russia)
Keywords: dental disease prevention; oral hygiene; dental disease in
children and teenagers"
: ;
;

Abstract: In writing Prevention of Dental Disease of Dental Hard Tissues

in Children and Teenagers, the overall aim was to identify the most
common dental diseases and the most effective prevention methods.
Referring to the rising number of children suffering from various dental
diseases, this work stresses the importance of prevention work at
schools and preschool institutions, including educational work with
parents.
.

.
,
,
,
6- 73%, 12 43,5%. .

102 | III
,
.


.
.

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2.
.
3.
.
4.

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5.

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;
2.

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;
3.
;
4.

2020. ,
,
. :
1.
:
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- ( 2- ),
;
2. ;
3. .

,
."

.
.., .., ..
[email protected]
, ,
,
: ... ..
ANALYSIS OF THE PREVALENCE OF CARIES AND ITS COMPLICATIONS
BETWEEN CHILDREN IN ODINTSOVO SITY.
Mhitaryan A.R., Stopycheva E.P., Alferova I.A.
Peoples' Friendship University of Russia, Russia, Moscow
The Faculty of Medicine, Pediatric Dentistry
Scientific Adviser: Ph.D. Tsareva T.G.
Keywords: Medicine, Pediatric Dentistry
:,

.

, : , ,
.


.
:
+ . 2010
1064
1,5 14 , 658 406
.
636 .
, ,
, 235
, 282
, 123
, 4 - .

131 ,
95 , 9.
, 244 ,
38 .
,
26%
,
21%,
15%,
13% ,
2,4%, 1,3%.

.
.., .., ..
[email protected]
- ,

,
,
: .. .., ... ..

CONDITION OF PARODONTAL TISSUES OF PATIENTS WITH

OSTEOPOROSIS
Ostaev Y.A., Siukaeva T.N., Khetagurov S.K.

 . , , , 2011 | 103
North Ossetian State Medical Academy, Vladikavkaz
the faculty of dentistry, Department of Prosthetic Dentistry, Department
of internal diseases
Science Adviser:Ph.D. Khetagurov S.K., Ph.D .Dzgoeva M.G.
Keywords: Osteoporosis, parodontal tissues, absorptiometry, mineral
density of bone tissue
: , ,
,
Introduction. Traditionally the problem of diagnostics and treatment of
osteoporosis is being explored by rheumatologists, in some cases
endocrinologists and gynecologists. However in practice the rate of
parodentium pathology in patients with osteoporosis makes up around
more than 70%. But unfortunately osteoporosis in most cases is
revealed when it is rather late.
Aim.Consequently parodentium pathology serves as a reason for
patients diagnosis in terms of early finding out whether they acquire
osteoporosis or not .
Material and methods: Thirty patients of both sex have been examined
aged from 37-65. They were divided into 2 groups. The second group
was control group actually. Total clinical examination was employed.
The information was gathered in terms of patientss complaints,
anamnesis of the main illness, taken medicines, examination for defining
the exact body weight, its index, taking clinical and biochemical blood
analysis. The density of bone tissue was defined by dual-energy X-ray
absorptiometry scanning.
Stomatological examination was based on the definition of number of
missing teeth, teeth injured by caries. Quantity of treated teeth. The
state of parodontal tissues we defined by analysing parodontal indexes
and clinical picture and complaints of patients . As a supplemental
method orthopantomogram was used.
Summary. After comparing the results of examination in both groups we
found out that pathological changes in parodentium of patiens with loss
of mineral density in peripheric skeleton were much more expressed in
patients with osteoporosis. And what is the most important the harder
the condition of parodontal tissues was the more marked the loss of
mineral density in peripheral bone tissue was.
Conclusion.In almost every patient with MPK there was detected any
form of parodentium tissue affliction. The level of afflicted area is
expanding when losing MPK is increasing in peripheric skeleton. So the
densitometry of bone tissue in patients with parodontal diseases is a
good measure in early revealing the osteoporosis and getting control
over it!"

.., .., .., ..,
..
[email protected]

.., ,
, ;

;
"
: ..,

MICRONUCLEUS TEST FOR ANALYSIS OF INFLUENCE DENTURE ON

THE GENETIC APPARATUS OF HUMAN.
Salnikov V.N., Poluhina N.V., Sheremetyeva A.S., Levina V.A., Egereva
M.A.
Saratov State Medical University n.a. V.I. Razumovsky, Russian
Federation,Saratov
Department of common biology, pharmacognosy and botany; Faculty of
Pharmacy.
Department of Orthopedic Dentistry, Faculty of Dentistry.
Scientific adviser: Durnova N.A., candidate of biology science
Keywords: denture, buccal epithelium, nuclear apparatus, micronucleus.

: , ,
,
Abstract: Investigation of influence denture on frequency
micronucleuss appearance in buccal epithelium cells. Majority
examining humans had increase frequency of aberrant cells.
,
:
*1+, *2+,
*3+ . *4+. ,
,
,
, .

,
.
,
,

*5+.
, 7

( 2 ).
( 35-40 )
(, ) .

. *7+.

,
1000 .
:
;
;
,
; ,

; 1/4 1/5 . *6+
15480 , 205
.
Stadia.
( %)
.


.
( 0,660,21%
1,980,73%,).
(83,3 % 97,7% ).


. (,

)
( 1,030,39%
3,910,40%). (,
,
)

0,380,13%,

0,540,43%) ,
.
,
: )
,
, ) 2

:
,
.

1. Lucero L., Pastor S., Suarez S., Durban R., Gomes C., Parron T., Creus
A., Marcos R. 2000. Cytogenetic biomonitoring of Spanish greenhouse
workers exposed to pesticides: micronuclei analysis in peripheral blood
lymphocytes and buccal epithelial cells. Mutat. Res. 464: 255262.
2. Ramirez A., Saldanha P. H. 2002 Gen. Mol. Res.1: 246-260.

104 | III
3. ..
// -
/ . .., ... .:
, 2007 312.
4. P.M., .., ..

/ // . - 1990.-.24, 2.-.57-60.
5. .. :
/ .., ...- .: . -
. , 1993.-68.
6. .., .., :

: - . . -, 2004. 29 .
7. ..
,
/..,
.., .., *.+//.-1998..40,7.
.686-689.

: 64%

, ,
; 20% -
; 16%-
.
:
.

.
.., ..
[email protected]
, ,
,
:... ..

ENDODONTIC, TREATMENT, DENTIST,QUESTIONING.

Jeludkova A., Borohova I.M.
Peoples' Friendship University of Russia, Russia, Moscow
The Faculty of Medicine,Department of propedeutics of stomatological
diseases
Scientific Adviser: Dr. V.S Bulgakov, Shapovalova S.V., Vereskova M.A.,
Razumova S.N.

ESTIMATION OF DYNAMICS OF CHANGE THE POSITION OF THE TEETH

IN A TOOTH ARCH ON THE BASIS OF A PROPORTION OF ""GOLDEN
SECTION"" BETWIN CHILDREN.
Stopycheva E.P., Alferova I.A.
Peoples' Friendship University of Russia, Russia, Moscow
The
Faculty of Medicine, Department of pediatric dentistry
Scientific Adviser(s): Ph.D. Tsareva T.G.

Keywords: Endodontic treatment questionnaire for dentists.

:
.

Keywords: Medicine, stomatology, orthodontics

: , ,
Abstract: Estimation of dynamics of change the position of the teeth in a
tooth arch on the basis of a proportion of ""golden section"" betwin
children.

- .

2 ,

, .

,
, .



.
:
. 100

7-14

4 4.
1:1,618 .
1:1.618 :
-
-
,

,
,

,
.


.

, ,,.
.., ..
[email protected]
, ,
,

: ..., ..,
.., .., ..

Abstract: Dentists were quizzed about the endodontic treatment, the

propriate conclusions the were made relying on obtained results.

1)

-
2)


3)
,

4)

5)


:

.
:
25
(, , , , , ).

.

,
..

(), .
,
.
:
5 . 25
40% , 60% .
80%
(Protaper, two), 20%
. 100%

:Step back Crown Down.
40-60 .
72% , 28%
. 64%
, 28%
, 8% . 25

 . , , , 2011 | 105
44%
, 32% , 16%
, 8% .
68% 3
, 28% , 4% .
28% , 72%
. 28%
, 72% .
- 46% , 52%.
,

,

.

9 .
.., ..
[email protected]
, ,
,
: .., - ..,
..
DETERMINING THE NUMBER OF ORAL FLUID MICROFLORA IN
CHILDREN AGED 9 MONTHS.
Kaneva D.A., Markova A.I.
Peoples' Friendship University of Russia, Russia, Moscow
The Faculty of Medicine, Department of stomatology of children's age
Scientific Advisers: Kosyreva T.F, Zaporizhzhya- Abramova E.S, Kravtsov
E.G
Keywords: micro flora, oral cavity, children, saliva, caries
: , , , ,

Abstract: Modern explorers assign Streptococcus mutans and

Lactobacillus as leading causes of the emergence and development of
carious process. The aim of our research was to examine the
relationship of quantitative structure Lactobacillus and Streptococcus
mutans of children aged 9 months and their mothers. We examined 45
children aged 9 months and their mothers. We extracted oral fluid into
a sterile tube. We used modern ready environment for seed Dentocult SM (Orion Diagnostica Oy, Finland) for detectioning of Streptococcus
mutans and MRS agar (HiMedia Laboratories Pvt.Limited, India) for
identifying Lactobacillus. According the results of researching, we found
that 46% of children aged 9 months have already the risk of developing
caries process. This confirms the necessity for prophylactic measures in
early childhood.
:

Streptococcus mutans Lactobacillus.
Lactobacillus
Streptococcus mutans 9 .
45 9 45 .
.

Dentocult SM (Orion Diagnostica Oy, )
Streptococcus mutans (HiMedia
Laboratories Pvt.Limited, ) Lactobacillus.
, 46% 9
.

.

Streptococcus
mutans,
, Lactobacillus,
( ..,
2010).

: Lactobacillus
Streptococcus mutans 9 .
: 45
9 45 .
9 .
Orion Diagnostica Oy
,
,
,
.
,
.

.
(Lactobacillus
Streptococcus mutans) .
Dentocult
SM (Orion Diagnostica Oy, ) Streptococcus
mutans (HiMedia Laboratories
Pvt.Limited, ) Lactobacillus.
,
.
9
Lactobacillus
. 4 ,
(38 ),

, .
(48 )
.
:
Streptococcus mutans-100%, 88% Lactobacillus.
40% Streptococcus mutans, 13% Lactobacillus.
Streptococcus mutans 0 (< 10 000 /) 9
9 , 18 ; I (<100 000/) 9
, 9 ; II (100 000-1 000 000 /) 9 9
, 13 ; III (>1 000 000 /)
, 5 .
, 21% 9
,

.

.., ..
[email protected]
.
,
: .., ..
TREATMENT OF THE PATIENT WITH A HERPETIC STOMATITIS WITH
APPLICATION OF LASER RADIATION
Svintsova M.O., Britova A.A.
Yaroslav-the-Wise Novgorod State University (NovSU)
Faculty of Dentistry, Stomatology chair
Scientific Adviser: Ph.D. Britova A.A.
Keywords:Herpes simplex, patient, treatment, pharmacotherapy, laser
radiation, hypoanalgation, healing
: Herpes simplex,, ,
, , ,
Abstract: Complex treatment of patients with a herpetic stomatitis with
application of low intensive laser radiation with length of a wave 0,63
nanometers raises the clinical efficiency caused
by action of radiation and its ability microcirculation and
process of regeneration of fabrics.


0,63
,

106 | III


.

.

..
[email protected]
, ,
,
: ..., ..
HYGIENIC DENTAL MEASURES INFLUENCE ON RESULTS OF
HAEMATOLOGICAL PATIENTS TREATMENT
Sokolova O.A.
Peoples' friendship University of Russia, Russian, Moscow
The Faculty of Medicine, Department of General Dentistry
Scientific Adviser: Ph.D. Avanesov A.M.
Keywords: Professional hygiene of mouth cavity, periodontal diseases,
periodont
: ,
,
Abstract: It has been proved that prophylaxis of dental diseases is one of
the most effective measures. Especially it plays an important role in
haematological patients treatment. Investigations of our Chair are
aimed for improvement of patients life quality. Our observation showed
that high level of oral hygiene allows to prevent further complications of
the main disease.
,
,

.
,

, 1970 .
().
33 06.02.11 .


.

. ,


, Privotella intermedia, Porphyromonas gingivalis,
Fusobacterium nucleatum .


, ,
.

.
,

,

, ,
. ,

-
,
.
,

: .


.

,

.
2009 2011 .
.

,

. 12
.
-
,
.
.

.
: -
-. ,
2,2-2,5() 1,9-2,4(-),
.
Lacalut
Aktiv: , , .
.
,

1,7-2,0() 0,9-1,4(-),
. 2
: 1,4-1,7() 0,5-0,8(-) .
,
,
, , .

, .

.
,

,

.

DENTAL STATUS OF PATIENTS WITH ISCHEMIC STROKE &

ATHEROSCLEROTIC ISCHEMIC HEART DISEASE
Farkasdi Sndor, Oszlnszky Judit, Dr.Yakovlev Michael, , Dr. Ibrohimov
Sherostan, Sokov Petr, Vignes Mohan, Rubanes Mohan, Dr. Prosvetov
Roman.
Department of Neurology and Neurosurgery PFUR, Municipal Hospital
.64, Moscow1
Department of Cardiology PFUR, Municipal Hospital .64, Moscow2
Department of Neurology Semmelweies University, Budepest 3
Scientific Adviser(s): prof. Sokov E.L.1, prof. Averkov O.V.2, Dr. Vastagh
Ildik 3.
Introduction: Stroke and Atherosclerotic Ischemic Heart disease are two
of the most common reasons of human death according to WHO
statistics. Teeth disease and oral hygienic is also a frequent problem in
the human civilization. There is not enough significant investigation
about the correlation between cerebral stroke, atherosclerotic ischemic
heart disease and pathology of teeth.
Aim was to explore our patient`s dental status, who had acute ischemic
stroke, stroke in the past and ischemic myocardial infarction and to find
out correlation between teeth reduction and lesion focus after stroke
and myocardial infarction. This pilot study was planned in two different
places to find out if there is any significance to our results or not.
Materials and methods: Firstly we observed 75 patients at Department
of Neurology of Municipal Hospital 64 of Moscow. 25 of them had
ischemic stroke in the past (half and more years ago). 50 patients had
acute ischemic stroke. Secondly, was observed 25 patient with ischemic
stroke at Department of Neurology of Semmelwes University. Thirdly we
are still observing patients at the Department of Cardiology, Municipal
Hospital 64, Moscow.
Our observation included dental examination and inquiry about dental
status. We took into account caries, plaque, extracted tooth,

 . , , , 2011 | 107
periodontium inflammation. Separately we estimate the number of the
lost teeth with respect to the insults` focuses.
Results: According to the aims of our investigation we got the following
preliminary results at the Department of Neurology and Neurosurgery in
Municipal Hospital 64 of Moscow. The average of the extracted teeth
on the homolateral side with the stroke in the acute period is 4,050,54.
The average of extracted teeth on the heterolateral side with the stroke
in the acute period = 5,30,49. The average of extracted teeth on the
homolateral side with the stroke in the past = 4,20,77. The average of
extracted teeth on the heterolateral side with the stroke in the past =
5,350,80. The 70,6% of the patients had bad level of oral hygienic.
Conclusion: At the present time, there is insufficient but suggestive
evidence for a possible causal relation between periodontal disease and
atherosclerotic disease (in both ways). If future studies show consistent
associations, periodontal disease may be elucidated as an independent
and potentially modifiable causal risk factor for atherosclerotic disease
and stroke can be one of the risk factors or edentulism also.
We express our deepest thanks and sincere gratitude to Prof. Dr. Berecki
Daniel head of the Department of Neurology of Semmelweis University
and to Prof. Dr. Gera Istvn from Department of Periodontology of
Semmelweis University.




. .1, . . 2, . . 3, . .3,
. .1, . .1, . . 4, .5
1
-
- ,

2
. .. , ,
3

,
4

,
5
,
A NOVEL TYPE OF A POLYTETRATIUORETHYLENE-BASED TISSUEENGINEERED CONSTRUCTION WITH NANOPATTERED
MULTIFUNCTIONAL BIOCOMPATIBLE NONRESORBED COATING
A.S. Grigoryan1, E.V. Kiseleva2, D.V. Shtanskij3, M.R. Filonov 3, ..
Khamraev1, A.K. Toporkova1, A.B. Gastiev4, Sh. Farkashdi5
1
Central Research Institute of Stomatology and Maxillo-Facial Surgery of
Federal Agency for High-Technology Medical Care, Moscow
2
Russian Academy of Sciences (RAS) Koltzov Institute of Developmental
Biology, Moscow
3
The Federal State Educational Institution of the Higher Professional
Education ((National University of Science and Technology (MISIS),
Moscow
4
Russian Medical Academy of Postgraduate Education, Moscow
5
Peoples' Friendship University of Russia. Moscow
Keywords: tissue engineering construct, functional coverage,
multipotent mesenchymal stromal cells of adipose tissue, bone
regeneration, cranioplasty.
Abstract: We preset a method for tissue engineering construct based on
highly porous PTFE with nanostructured multifunctional biocompatible
non-degradable coating (MBNC) with composition of Ti-Ca-P-C-O-N. It is
shown that scaffolds composed of PTFE with MBNC are suitable for
adipose-derived multipotent stromal cells (ADMS) active adhesion and
proliferation. Under osteogenic stimulation ADMS cells were
differentiated to osteogenic lineage, which was confirmed by positive
immunohistochemical reaction for osteopontin and osteonectin. Using
the experimental model of critical calvarial defects in rabbits we
investigated the influence of tissue engineering construct (membrane
from highly porous PTFE with MBNC carrying ADMS cells)
transplantation on bone defect regeneration. It was shown that under
tissue engineering construct the bone defect was completely closed with
newly formed bone tissue in 3 and 6 months after transplantation.
,

()
,

)
,

.

,
: ,
().


()

()
Ti-Ca-P-C-0-N

.

()

() Ti-Ca-P-C-0-N.,
.

,
,

. in vivo

Tt-Ca-P-C-0-N,

. 3 6 .

,
.
, , ,

,
--
.

. .
[email protected]
, ,

, -

() ():... . .
ATRUMATIC TOOTH EXTRACTION
Agapov A. V.
Samara State Medical University, Russia, Samara
Faculty of Dentistry, Department of Maxillofacial Surgery and Dentistry
Scientific Adviser(s): Ph.D. Belanov G. N.
Keywords: Atraumatic, removal, extractions, prophylaxis, resorption

:
,
,
,
,
The aim of atraumatic removal is to minimize bone resorption after
tooth extraction and to preserve its volume.
When the classical scheme of healing alveolar socket after removal takes
place, epithelialization occurs at 4 - 18 days after extraction, after 30
days it is filled with osteoid tissue, 4 month - the formation of compact
bone at the top of the socket takes place. These terms of regeneration
in a well extracted tooth alveoli are valid only for ""ideal"" conditions.
When there is a trauma of walls of the socket and surrounding soft
tissues, which takes place almost always in the 'traditional' removal,
the terms of complete regeneration increase by a considerable period.
There is a significant resorption of the structural elements of the
alveolar bone. Consequently, it is necessary to achieve the minimal
trauma to periodontal structures when removing a tooth.

108 | III
We have formulated the basic principles of atraumatic tooth extraction:
the direct impact on the ligaments of the tooth, the account of
biomechanics of the tooth and surrounding tissues. We analyzed the
methods and means used for atraumatic tooth extraction .
Clinical case
Patient K. 36 years old, approached a clinic about the recurring pain in
4.6 tooth. According to the complaint, medical history, examination and
the X-ray, chronic granulating periodontitis of 4.6 teeth was diagnosed.
We decided to remove this tooth and to install two implants: in the area
of previously removed 4.7 tooth and one-stage implantation in the
region of 4.6 teeth. 4.6 was atraumaticly removed. Atraumatic removal
allowed to keep all of the alveoli walls and interaradicular septum,
which contributed to the primary stabilization of the implant installed
within 35-40 H.

.
..
[email protected]
-
, , -
,

() ():... ..
TREATMENTS EFFICIENCY AMONG PATIENTS WITH TEMPOROMANDIBULAR JOINT DYSFUNCTION.
Babich V.V.
St.Petersburg Medical Academy of Post-Graduate Study, Russia,
St.Petersburg
The Faculty of Dentistry, Department of prosthetic
dentistry
Scientific Adviser(s): M.D. Cimbalistov A.V.
Keywords: Temporomandibular joint dysfunction, pain symptom.
: - ,
.
Abstract: Statement of problem.
Temporomandibular joint dysfunction syndrome (TMD) leads among
temporomandibular disorders (Deodato F. et al., 2003; Seedorf H. et al.,
2002; Steed P.A., 2004; Turp J.C., Shindler H.J., 2004). The correlation
between the endocrine pathology and temporomandibular joints
dysfunction syndrome is proved, moreover it affects women more often
than men (Dao, T.T. et al., 1998; Raphael, K.G., Marbach, J.J., 2001).
Hypothyroidism is often followed by myofascial pain syndrome (Travell
J.G., 1989; Simons D.G., 1985, 1990, 1999). As the treatment of this
particular group of patients has not always shown stable improvements,
our researches have been directed to this area of medical studies.
Material and methods.
117 patients with temporomandibular joint dysfunction were observed.
The researches included the following methods: clinic interviewing of
patients and filling in visual pain reaction chart; gnathodynamometry;
spectral-photometry of haemodiluted capillary blood. Heart rate
variability.
Results.
When viewing the analogue chart of pain reaction, it has been observed
that 32.3 % of the patients from the control group and 31.9 % of
patients from the research group did not show pain symptom. However,
after the treatment the number of patients without pain symptom from
the research group increased to 50 % compared to 34 % of these from
the control group.
Conclusion.
Rehabilitation's efficiency depends of somatization level and health
compensation; the gnathodynamometric test proved that patients of
the research group demonstrated increase of the bite strength on the
frontal side. The recommended complex treatment (endocrinological
treatment) can help to avoid complications during the prosthetic
treatment and contribute to clinical improvement.
.

-
, (Dao T. T.
et al., 1998; Raphael K. G., Marbach J. J., 2001). A. U. J.

Yap . (2002),
-
.
:
.
. 2006 2010
117
- (102 15 )
2260 .
,
. ,
(
)
(n=57). ,

()
,

(n=60).

(, /
).

( ).

().
50
- .
- .

.
. , ,
, (87,18%).

(47% ,
50%

).


.

c2 c2 Pearson
(<0,05).
.
.
45 .
50% .
34%
.

1,7
; ANOVA (<0,0001).
.
()
.
J. G. Travell (1989, 1990) D. G. Simons (1985,
1990, 1999),
, ,
-
. Argov Zohar, Renshaw Perry F., Boden Barry,
Winokur A., Bank William J. (1988),

,
.

.
..
[email protected]
, ,
,
.
() (): ..
THE RESEARCH OF TRANSVERSAL SIZES OF DENTAL ARCS AND THE
SIZES OF INCISORS USING THE PON METHOD.
Glinkin A.V.

 . , , , 2011 | 109
Peoples' Friendship University of Russia, Russia, Moscow
The Faculty of Medicine, Department of pediatric dentistry with course
of orthodontics
Scientific Adviser(s): Tsareva T.G.
Keywords: Dentistry
: , ,
Abstract: By using the Pon method we evaluated the efficiency of some
orthodontic treatments.
: .
:

32

. 5
, 4 , 5
2
.


.

.. (1995).


.

.
, 18%
3 .
43%
1 . 10% ,
c .

CPITN
: - ,

..
[email protected]
, ,
,
() ():... . .
COMPARATIVE ANALYSIS OF CPITN INDEX PREVALENCE BETWEEN TWO
GROUPS OF PATIENTS: EMPLOYEES OF THE RAILWAY INDUSTRY AND
OTHER PATIENTS.
Didina A.A.
Peoples' Friendship University of Russia, Russia, Moscow
The Faculty of Medicine, Department of General Dentistry
Scientific Adviser(s): PH. D. Avanesov A. M.
Keywords: periodontal diseases, clinical investigation, patient, oral
hygiene, stress, CPITN index
: , ,
, , , CPITN
Abstract:Based on CPITN index prevalence between two groups of
patients to show the professional impact on the incidence of
periodontal diseases among employees of the railway industry.
: CPITN

.
:
30 25 50 ,
( 10
, 15 5
) 30 ,
.

- .
CPITN

.
: CPITN
, ()
0 , 1,2,3,4 0,
44 0, 11; 2,6 1,75; 1,73 1,3; 0, 39 0,10 .
, (
2,3,4) 4,72 1,89.

0 1,23 0,11, 1,2,3,4 0,28 0,11; 2,1
1,5, 1,2 1,0; 0,15 0,10 . ,
( 2,3,4)
3,45 1,3.
.
: ,
, CPITN
() ,
. ,
, :
, , ,
., , , .
(
:
,
) .

!
...
[email protected]
, ,
,
() ():... ..
PERSPECTIVE OF ANTISEPTIC PREPARATIONS MYRAMISTIN FOR
PREVENTION AND TREATMENT OF DISEASES PERIODONTAL TISSUES!
Kalantarov.g.k.
Peoples Friendship University of Russia, Russia, Moscow
Faculty of Medicine, Department of General Dentistry
Scientific Adviser(s): Ph.D. Avanesov A.M.
Keywords: Miramistin, periodontitis, immunity, or microorganisms.
: , , ,
.
-
,
.
, ,
40-50 ,

.
,
40
50%.
:


, ,
,
.


.

110 | III

, .


,
, ..

,
.
,
,
.

- , , ,
( IgA,IgG ) .
IgA

,
, , ,
,
,
.

.
,

, ..
.
,


;
,
.


.
, ,
,
.
,
,
,
, ,
,

,
() .
,
.
,
,
.
,
,
,
, .

,
.

, :
,
.

, ,
, ,

. (
,,,,

).
1000 .

(,

). ,
(
). (
,
).

,
.

.
.
, .
- .

.
,
,
,
.

.

,
,
.

-
.., ..
[email protected]
, ,
,

() (): ... .
ANALYSIS OF STUDENTS' PROGRESS AT THE DEPARTMENT
""PROPEDEUTICS DENTAL DISEASE "" WITH THE USE OF POINT-RATING
SYSTEM"
Kalmurzaev B.K., Simonova I.A.
Peoples' Friendship University of Russia, Russia, Moscow
The Faculty of Medicine, Department of propaedeutics of stomatologic
diseases
Scientific Adviser(s): Ph.D. Bullgakov V.S.
Keywords: the progress analysis,progress for 4 semester,result of
progress
: ,
, 4 .
Abstract: Article is devoted the analysis of progress of students stomatologists on chair of propaedeutics of stomatologic diseases of
which we observed during 4 semester. We observed of progress of
students by means of results of control tests on ballno-rating system.

,
.
: ,
I III .
,
,
.

:
1.
.
2. .
:
120 5 4
.
, -
.
: 4
,
,
,

 . , , , 2011 | 111

.

.
.., ..
[email protected]
, ,
,

() ():... ..
TECHNIQUE OF MANUFACTURING OF THE DOMESTIC UNIVERSAL
STOMATOLOGIC PHANTOM FOR TRAINING OF STUDENTS.
Kalmurzaev B.K., Simonova I.A.
Peoples' Friendship University of Russia, Russia, Moscow
The Faculty of Medicine, Department of propaedeutics of stomatologic
diseases
Scientific Adviser(s): Ph.D. Bulgakov V.S.
Keywords: The phantom, method of manufacturing of the stomatologic
phantom.
: ,
.
Abstract: The article is devoted to the production of domestic universal
dental phantom for teaching students about dentists., Manufacture and
application of universal dental phantoms allows student-dentist in the
acquisition of manual skills in conducting therapeutic manipulation: the
treatment of dental caries, endodontic treatment of orthopedic
manipulations: the production of various prosthetic restorations;
surgical procedures: tooth extraction surgery, amputation, hemisection,
root apex resection.

,
.


.
,


.

,
,

.

.

,
.


, .
:
1.

.
2.
.
3.

: , .
4.
:

, , , .

5.

:
.

, 7

.

: ; ;
(); ;
. , ,
6 , : (
), ( ),
. ,
.
.
() .
.
, .
.

. ,
()
:
1.
.
2. .
3.
,
.
4.
.
5. :
, , ,
.
6. 4-6
.
:

,

.

.
.., .., ..,
..
[email protected]
, ,
,

() (): ... ..
USE OF VISUAL AIDS AT THE CHAIR PROPEDEUTICS DENTAL DISEASES.
Kalmurzaev B.K., Simonova I.A., Nikulnikov M.A.
Peoples' Friendship University of Russia, Russia, Moscow
The Faculty of Medicine, Department Propaedeutics of stomatologic
diseases
Scientific Adviser(s): Ph.DBulgakov V.S.
Keywords: visual aids, perception, learning process.
: ,, .
Abstract: Summary of the article is devoted to the influence of visual
aids on the quality of learning students. Object of study is the learning
process, and the subject of study, the use of visual aids. With the use of
control tests and oral responses, it was found that the use of
educational stands undoubtedly promote learning. Thus, the
manufacture and use of educational stands, provides invaluable
assistance in learning the material and, as a consequence of the most
high-quality training of young professionals.

112 | III
, , ,


.
, .


,
.
, ,

, ,
.
:
.

:
1.
- .
2. ,
;
3.
4.
.
,
, .

.
.
- ,
.
, , ,
.
07 07
2011 , 1-5 .
2
. II
, 1 5.
.
- , 1, - 2-5.
2-5
, 1 .
.
,

.
:
( ,

),
.
.
:
, ,
,
, .
.
,
, ,
-
.

..
[email protected]
, ,
,
() (): ..., ..
THE IMPACT OF ANTISEPTICS ON THE ORAL LIQUID
Kirik O.P.
Peoples' Friendship University of Russia, Russia, Moscow
The Faculty of Medicine, Department of General Dentistry

Scientific Adviser(s): Ph.D. Avanesov A.M.

Keywords: antiseptics, oral liquid, immune response, chlorhexidine,
miramistin, diseases of the mouth
: , , ,
, ,
Abstract: Treatment for most dental diseases associated with the use of
various antiseptics. There are two generations of antiseptics. The
greatest number of publications related to the description of the
effectiveness of chlorhexidine, which has disadvantages, it changes the
color of tooth enamel, is toxic and cause dysbiosis mouth. Deprived of
the attention is domestic aptiseptik miramistin, it does not suppress the
local immune response, is not carcinogenic and embryotoxic effects.

. Peter F.Fedi
William Killoy : ,
, (,
, ), ,
20-50%,
, , ,

70-90%.
,
,

- (0.050.12%) , ,
, ,
( 0.01%),

.

.

. ,
10 - .

. ,
, ,
, ,
,

-
,

. ,

, ,
.


, ,

. :
, , ,
, ..
, ,
,
.

, .
,
,
.
.

.., ..
[email protected]
-
. .. , ,

 . , , , 2011 | 113
...,
() ():. ..
METHOD OF PROPHYLAXIS OF EARLY AND LATE COMPLICATIONS
FOLLOWING DENTAL IMPLANTATION CRYOSURGERY IMPACT
Mikhajlov A.E., Kuznetsova N.L.
Ural Scientific Research Institute of Traumatology and Orthopedics. VD
Chaklin Ministry of Health and Social Development of Russia
Department of Prosthodontics
Scientific Adviser(s): Ph.D., prof. Kuznetsova NL
Keywords: Dental implantation, prevention of complications,
kriologichesky treatment
: ,
,
Abstract: The first experience cryological influences to 10 patients with a
common somatical pathology with the preventive and medical purpose
for achievement of secondary osteointegration before installation
cylindrical titanic implants or in cases of repeated implantation in
connection with unsatisfactory result of primary operation is resulted.
The positive result is received.
.

.

.
,

, -
.

, .
,
, .
.

.
. 10
. 5

()

. 5

.

,
,
,
,
.
.
.
,
,
.

.
,

,
30%. ,
,
,
.
10
.
,
,

;
,
( )
.

5
5 ,
.
()

. ,
, .
2007 2010 .
. 5

.

,
, . 5 ,

,
.

..
[email protected]


-

, , -

() ():... . ., ...
. ., ... . .
ASSESSMENT OF PERIODONTAL TISSUE DESTRUCTION IN PATIENTS
WITH AGGRESSIVE PERIODONTITIS
Natsvlishvili T.T.
St-Petersburg Medical Academy of Postgraduate Studies, Russia, SaintPetersburg
Department of Dentistry
Scientific Adviser(s): Ph.D. Tsimbalistov A.V., Ph.D. Kadurina T.I., Ph.D.
Shtorina G.B.
Keywords: aggressive periodontitis, periodontal attachment loss
: ,

Abstract: Severity of aggressive forms of periodontitis, peculiarity of age

group and the nature of the clinical manifestations causes particular
interest of researchers and clinicians. Our study showed a difference
between the values of periodontal pocket depth and attachment loss in
patients with aggressive periodontitis, which ranges from 1 to 4 mm.
,

.

.
: 23 20
35 (10 20 )
20 35 50 (8
12 )
.
,

(), ..

, () -
-
.
:

-

78%
2/3
. 65%
. 35% 6 ,
70% 6 .

69%
2/3
: 6 46% ,
92% 6 .

114 | III

,
() ,
.


, 1 4
.
.

.., .., ... .
[email protected]
, ,
,
() (): . ... ..
DISTINGUISHING PSEUDOEPITHELIOMATOUS HYPERPLASIYA FROM
SQUAMOUS CELL CARCINOMA OF ORAL MUCOSA.
Prokopyev V.V., Belov K.V., Ph.D Koviazin V.A.
Peoples' Friendship University of Russia, Russia, Moscow
The Faculty of Medicine, Department of pathology
Scientific Adviser(s): Prof. Ph.D. Babichenko I.I.
Keywords: squamous cell carcinoma, pseudoepitheliomatous
hyperplasia, immunohistochemistry, hematoxylin-eosin.
: ,
, , -
Abstract: The article concerns about histological appearance of
pseudoepitheliomatous
hyperplasia.
Distinguishing
pseudoepitheliomatous hyperplasia from squamous cell carcinoma can
be difficult. A new method of differential diagnostics, based on
immunohistochemistry, is performed in the article.
.

, -

.
,
. Glut-1 . 492 .
, , 1- . Glut-1
. Glut-1

.
,
, Glut-1


.
.

Glut-1 .
.

2007
2010 ( ... .. ).
10 : 5
5
. 62 .
Glut-1
(SPM4098, Thermoscientific,
1:100).


(BioGenex).


.

Glut-1
.
Glut-1 1- 2- -
,
.


.
. Glut-1,




.

.., ..
[email protected]
-
, , -

() (): ..., ..
INFLUENCE OF POSTERIOR TEETH LOSS ON THE FUNCTIONAL STATE OF
MASTICATORY SYSTEM
Simonenko a.a., Ovsyannikov k.a.
St-Petersburg Medical Academy of Postgraduate Studies, Russia, SaintPetersburg
The Faculty of Dentistry, Department of prosthodontics
Scientific Adviser(s): Ph.D. Cimbalistov A.V.
Keywords: posterior tooth loss, electromyography, stabilometry,
bioelectrical activity, functional state, masticatory system
: , ,
, ,
,
Abstract: The purpose of the research is the evaluation of adaptation
rate of muscular-articulation system in the case of posterior teeth loss.
Functional state of the muscular-articulation system was measured with
the use of computer-assisted stabilometry and surface
electromyography of masseter and temporalis muscles.

,
.

,

.
.


. . 18
32 55
(I Kennedy). 6 12 .
: ,

,
.

-01-2.
,
- ,
,

.
:
-
,

 . , , , 2011 | 115
.

() .

,
.
()
,
,
.
.

()
6 18 (33% )
0.03 0.06 , 12
18 (66% ) ( 0.009
0.02 ),
7 18 (39% )
( 0.03 0.06 ), 11 18 (61%
) 0.09 0.28 .


0.35 *,

0.48 *.
80 120%,

20% 78% 130 340%.
, 18
15 (83% )

,
.
:
1.

,
.

.
2.
-
,
.

.
[email protected]

()
() (): . ...,
.., ...,
A ROLE OF MATRIX METALLOPROTEINAZE AND PERIODONTAL
DESEASE
Tebloeva L.M
Moscow state universiry of medicine and dentistry
Scientific Adviser(s): Konstantin G. Gurevich, MD, PhD, DrSci, Prof
Moscow State University of Medicine and Dentistry
Keywords: MMP, periodontal desease
: ,
Abstract: The pathogenesis of periodontal disease (PD) is an
inflammatory process involving innate and adaptive immune responses.
PD is characterized by the host-mediated destruction of soft tissue
caused by the induced production and activation of lytic enzymes and
stimulated osteoclastogenesis. Although it is widely recognized that PD
is chronic, the nature of the chronicity has not been established. It is
uncertain whether PD is a continuous process or consists of episodes of

exacerbation and remission. Furthermore, the duration of the periods of

exacerbation, if they exist, is not known.

(MMP)
- - ,
( ,
) (,
, ),
. MMP
,

(,
,
,
). MMP
(,
) .

.., ..
[email protected]
, ,
, -

() (): ..
FEATURES OF A MICROBIC LANDSCAPE OF A MAXILLARY BOSOM AT
A SINUSITIS
Tokmadzyan E.O., Ezoyan M.V.
Peoples' Friendship University of Russia, Russia, Moscow
The Faculty of Medicine, Department of maxillofacial surgery and
surgical stomatology
Scientific Adviser(s): Ph.D Gynko V.I.
Keywords: sinusitis
:
Abstract: Has finished medical faculty RUDN in 2008,
The clinical intern of 2nd year on chair of maxillofacial surgery and
surgical stomatology RUDN
.

5-8%
- . 10
3 .

, -.
,

.
, ,

,

.


.
,
, ,
. ,


, (..
, 1990; .. ., 1996; James R.B., 2000).

,
,
, ,
, .
,


Caldvell-Luc (1893, 1897), .. ,
(.. , ..
, 2003), ,

116 | III

.



,
.

,
.

.


, ,
per os
.

.

, ,
,
,

, ,
.



,
.
. 2
56
, 35 ,
,

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.
.


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, 14
8
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,

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,

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, -. ,

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, .
,
.
,
Aspergillus , ;
.
,
.

.., .., ..
[email protected]
-
,,-
,

() (): .
..,. ..
STUDY OF INTERACTION BETWEEN PERIODONTAL DISEASE AND
CARDIOVASCULAR
Cimbalystov A. V.,Shtorina G. V. ,Eliseeva A. F.
Medical Academy of Postgraduate Studies(SPb MAPS) , of Russia,SantPetersburg
The Faculty of Stomatologi Departament of ortopedi
Scientific Adviser(s): Cimbalystov A. V.,Zinserling V. A.
Keywords: Periodontitis ,Chronic generalized, periodontitis Coronary
disease ,cardiovascular
: ,,
,
Abstract: The problem of periodontal disease has general medical and
social importance. According to the WHO (1990) more than 98% people
in the world is amenable to periodontal disease, which going to loss of
teeth, the appearance of nidus of persistent infection, reduce the
reactivity of the organism, microbial sensitization. The analysis of the
literary given domestic and foreign authors shows, that to date has
accumulated plenty of evidence of association generalized inflammatory
periodontal lesions with different diseases of internal organs. Pathology
of the cardiovascular has a particular place. (Roos R 1999 Wu T 2003,
DeStefano 2005)

- ().
- .
100 ,50
()
50 , 40 60 .
,

, , ,
, .
,
: OHI-S (G&V),
CPI ( CPITN), Muhieman H. R. (1971),
Muller-a ( Fleszar 1980),
P.D. Miller (1985),
Hamp-y (1975).

.

( .. 2004).
.

.

,
. , ,

 . , , , 2011 | 117
. ,
,
,
, .

[

,

,
.]

[
]

[SURGERY AND TRAUMATOLOGY]

 . , , , 2011 | 119
CLINICAL ANATOMY OF THE EXTRA- AND INTRAHEPATIC ARTERIAL
BLOOD SUPPLY OF THE HUMAN LIVER
Kroly Nmeth1, Lszl Kbori2, Mtys Kiss1, Andrs Szuk1, Csaba
Korom3, Endre Gti1, Ildik Horti1, Zsolt Ppai1, Klra Tr4, gnes
Nemeskri1
Semmelweis University Budapest,
Department of Human Morphology and Developmental Biology,
Transplantation and Surgical Department,
3
Department of Diagnostic Radiology and Oncotherapy,
4
Department of Forensic and Insurance Medicine
Introduction: Detailed knowing of the arterial variations supplying the
human liver is essential for the preoperative planning and performance
of liver surgeries, especially for the split and living donor liver
transplantation.
Aim: Our goal was to investigate the anatomical variations of the extraand intrahepatic arterial blood supply of the liver and the incidence of
these variations in the Hungarian population.
Materials and methods: Using corrosion technique we examined the
intrahepatic arteries on 39 liver casts and the extrahepatic arterial
variations on 37 abdominal organ complexes. The arteries were injected
through the abdominal aorta with resin and after its hardening the
parenchyma was corroded. Digital photographs and 3D CT images were
taken of the preparations. The originating and coursing patterns of the
artery of liver segment IV was classified according to Jin (2008), the
extrahepatic arterial variants were categorized according to Michels
classification (1966).
Results: Out of 37 organ complex preparations we found extrahepatic
arterial variations in 11 cases (29,7%). One preparation could only be
classified according to Hiatt (1994) and another preparation had a
vascular structure which has never been described before. The origin of
the artery of segment IV was the left hepatic artery in 16 cases (41%);
the right hepatic artery in 11 cases (28,3%); the proper hepatic artery in
3 cases (7,7%); and we found double segment IV arteries in 9 cases
(23%) which is a much higher incidence than found in the international
literature. In 6 cases (15,4%) the artery of segment IV originated partially
or totally from the artery of segment III, in 5 cases (12,8%) the artery of
segment II gave branches to the segment IV.
Conclusions: Precise knowledge of the different types of extrahepatic
arterial variations is crucial for surgeons to safely perform liver
resections, organ harvesting, surgeries on the stomach and particularly
during liver transplantation. The intrahepatic variations play an essential
role in split and living donor liver transplantation. In Hungary we were
the first to examine the anatomical variations of the extra- and
intrahepatic arteries together on human organ complexes by making
corrosion cast preparations. Our data may contribute to the planning
and safer performance of all surgical and radiological interventions in
the upper abdomen.

:
.., .., .., ..
[email protected]
, ,
,
() (): ... ..
EFFECTIVENESS OF OPERATIVE TREATMENT OF MULTIPLE
OSTEOCATILAGINOUS EXOSTOSIS IN CASES OF TENDENCY TO
SARCOMATOUS DEGENERATION EXOSTOSES OF THE THORACIC SPINE:
A CASE REPORT
Osmakova A.A., Kirichek A.A., Abdrakhmanov R.R., Lebedev E.I.
Peoples' Friendship University of Russia, Russia, Moscow
The Faculty of Medicine, Department of traumatology and orthopedics
Scientific Adviser(s): Dotsenko V.V., PhD
Keywords: multiple osteocartilaginous exostosis, operative therapy,
sarcomatous degeneration.
: ,
,

Abstract: Surgical treatment of spine tumors is directed to ensure

radicalism in consideration of anatomical proximity to spinal cord. The
purpose of the study is the development of methods for radical surgical
ablation as part of complex therapy of MHE in the spine. PCITO has
gained experience in treating of 78patients.The preliminary results
testify that radical treatment offers the possibility to relieve symptoms
of spinal cord compression, verify the tumor process and increase
oncological radicalism.
Background: Multiple osteocartilaginous exostosis, also called multiple
osteochondromatosis, multiple hereditary exostosis (MHE), is an
osteochondroma that results from a dysplasia of peripheral growth
plate. MHE occurs in 1 out of 50,000 people. MHE is typically inherited
as an autosomal dominant trait. MHE produces multiple bony growths,
often on the metaphysic of the tubular bones (in over 90% of cases
distal tibia, proximal tibia are involved). Exostoses may lead to bone
deformities, skeletal abnormalities, short stature, nerve compression
and reduced range of motion. Patients with MHE have an increased risk
for secondary chondrosarcoma after the age of 21 years. Most of the
time, multiple osteochondromas are not removed surgically. Surgical
interventions are possible, and vary. As regards surgical treatment of
spine tumors, it is directed to ensure radicalism in consideration of
anatomical proximity to spinal cord and the spine stabilizing. However, a
single viewpoint on the amount, type, operational approach and tactics
of the operative treatment has still not been reached.
Objective: The purpose of this study is the development and
improvement of methods for radical surgical ablation as part of complex
therapy of MHE in the spine including cases with sarcomatous
degeneration.
Methods: Priorov Central Institute of Traumatology and Orthopaedics
(PCITO) has gained experience in treating of 78 patients:29 (37,5%)
patient with MHE and 49 (62,5%) patients with MHE with sarcomatous
degeneration. Indication for surgery is the presence of clinical symptoms
under the condition of thoracic spinal exstose and the lack of invasive
growth to the spinal cord. Radical surgeries of tumors such as block
resections of vertebra or fragment resection in the range of sound
tissues using methods of blood loss reduction, ablastic safety and
complex antineoplastic actions were performed. Individual hardware,
multilevel endocorrectors and different types of interbody fusion were
applied for stabilizing the vertebral column. The following case report
demonstrates the efficiency of radicalism in the surgical treatment of
spine tumors.
Results: On October 2010, an 18-years-old man came into PCITO after a
minor fall with symptoms of difficulty in walking and ascending
numbness involving the lower extremities. He was hospitalized with
clinical diagnosis Multiple osteocartilaginous exostosis with spinal cord
compression and risk of sarcomoutos degeneration. At 5-years old, he
first noticed a growth on the thoracic part of the back, then
osteochondroma of thoracic spine(T4) was diagnosed, but it wasnt
removed surgically. Since April2010, he noticed a tumor growth, in two
months he first complained of slight incoordination of the lower
extremities. Neurological examination revealed a progressive spastic
paraparesis, a conductor hypesthesia on the level of T4-T6 bilaterally,
temporary pelvic disturbances. On physical exam, a solid fixed growth
with tenderness on palpation was found out. CT of the thoracic spine,
performed to characterize the lesion, showed an ovoid 2-cm mass at the
superior endplate of T4 with soft-tissue density centrally. The lesion
caused severe narrowing of the central spinal canal. A preoperative
chest radiograph revealed two osteochondromas overlying the left 1-st
rib and the right 4-th rib and a scapular osteochondroma. At surgery, the
lesion resembled a pearly brown tumor. The patient recovered partly
with moderate residual deficite (mosaic sensitive disorder on the level
T4).Pathologic specimens revealed the lesion to be an osteochondroma
with dystrophic changes.
Conclusion: The preliminary results testify that radical surgical treatment
implementation for spine lesions during MHE offers the possibility to
relieve symptoms of spinal cord compression (100%) and improve
neurologic symptomatology (76%), verify the tumor process and
increase oncological radicalism(47%). Eventually complex surgical
therapy increases the life time and quality.

120 | III


.., .
[email protected]
, ,

,
() (): ... ..
FEATURES OF A CLINICAL COURSE OF ACUTE CHOLECYSTITIS IN THE
AGED
Bashatova A.N., Sherekesheva A.K.
Orenburg State Academy of Medicine, Russia, Orenburg
Medical Faculty, Department of faculty surgery
Scientific Adviser(s): Nuzova O.B., MD
Keywords: acute cholecystitis, laboratory and instrumental data, surgical
treatment, accompanying pathology, complications, mortality

,
, ,
, ,
Abstract: Acute cholecystitis remains one of the most actual problems in
surgery, especially in elderly patients with the severe associated
pathology. Results of examinations and treatment of 64 aged patients
with acute cholecystitis. For aged patients typically early and rapid
development of purulent-necrotic process in the gallbladder wall, while
clinical picture does not always correspond to the morphological
changes in the gallbladder wall and the abdominal cavity.

.
: 1)
. 2)

.
: 64
,
. .. .
2010.
86% (55
), 14% (9 ).
70-79 44% (28 ),
60-69 34% ( 22 ).
: 55% (35)
,

.

- ,

.
73% (47)
. 51% (24
)
.
53% (25) 3
, 47% (22) .
27% (17) , 88% (15)
,
.
82% (14) .
77% (13) .

47%
(8)

.
29% (5) ,
18% (3) . 1

.
2-
65% (7)
(, )
.

73% (47)

.
- : 79% (37 ),
89% (48 ),
70% (33 ), 38% (18
). 34% (16)
,
21% (10 ).
88% (15) .
33% (5) , 20% (3)
, 7% (1) ,
.
3% (2 ). 1
- ,
.
: 1. ,

,
. 2.


.

,

..
[email protected]
, ,

- , ,
- () ():
... ..
COMPARATIVE STUDY OF REFLE[ VASCULAR SYNDROMES AMONG
PATIENT WITH DEGENERATIVA SPINE DISEASE, OPERATED WITH THE
USE OF DYNAMIC AND RIGID FIXATORS
Betts A.Y.
Ural State Medical Academy, Russia, Yekaterinburg
The Faculty of medical-prophylactic, Department of traumatology,
orthopedicsand military surgery
Scientific Adviser(s): Chertkov A.K, Ph.D.
Keywords: degenerative spine disease, spine surgery, reovasography,
reflex vascular syndromes
: , ,
,
Abstract: Comparing the results using of rigid and dynamic fixators
demonstrated that dynamic stabilization to a lesser extent retained
residual pain, at an earlier date is eliminated stimulation of sympathetic
nervous system, which provides optimal functional conditions for the
regeneration of a damaged disk, preventing further degenerative
changes and optimal postoperative adjustment of patients to normal
life.



.

.

,

.
.

38
.
.
.

 . , , , 2011 | 121
17 - , 35 45
( 39,73,2 ).

.
21 , 35 45
( 37,84,5 ).

( )
(
(), ()
(), ()).
, 10 6
.




38 .

:
- 8,3 1,1, 7,9 1,7 (>0,05). 6

3,41,2, 1,40,9 (<0,05).

13,1%,
,
(5,2%).

79%
, 12%,
9% .
10
25% 5% ,
- 65% 30% ,
10% 65%
.
,
19%
8% .
:
1.

.
2.
.

- ,

.., ..
[email protected]
, ,

() (): ..., . ..
NON-INVASIVE TECHNOLOGIES IN TREATMENT OF CHILDREN WITH
VENTRICULAR-PERITONEAL SHUNT CIRCUIT COMPLICATED BY
PRIMARY PERITONITIS
Generalov N.S.,Gorodova A.V.,
The Russian State Medical University, Russia. Moscow
Pediatric faculty
Scientific Adviser(s): Bichkov V.A., Ph.D.
Keywords: shunt, peritonitis, children
: ,
Abstract: Today in children with hydrocephaly after ventricular
peritoneal bypass surgery complicated with peritonitis laparoscopy is an
optimal, non-traumatic and advanced method of treatment.

:
() - ()
.
: - ,
2005-2010 .
:
8 8 15 .
,
.
.

, , ,
, .

,
, ,
, .
: ,

, ,
, .
: ,
,

-
,

,

.

..
[email protected]
-
, ,

() (): ..., ., ..
THE USE OF MULTISLICE SPIRAL T ANGIOGRAPHY IN THE DIAGNOSIS
AND PLANNING OF SURGICAL TREATMENT OF PATIENTS WITH
EXTRACRANIAL ARTERIOVENOSUS MALFORMATION
Gulinov K.A
Moscow State Medical and Dental University, Russia, Moscow
Department of Hospital Operative Dentistry and Maxillofacial Surgery
Scientific Adviser(s): Grishin A.A., Ph.D.
Keywords: multislice spiral CT angiography , extracranial arteriovenosus
malformation , lead and efferent vessels, visipaque.
:
(-), - (),

Abstract: The aim of the study was to explore the use of multislice spiral
CT with angiography in the diagnosis and planning of surgical treatment
of patients with extracranial AVM.
The method of multislice spiral CT was used in 15 patients with
extracranial AVM of the maxillofacial region. After the multislice spiral
CT with angiography in all patients were diagnosed extracranial AVM
with the exact location, their relationship with neighboring organs and
tissues and vascular architectonics of lead, efferent and adjacent
vessels, that helped to select an effective surgical treatment.
:
,
-

- ()

,
.

122 | III


.
( ) -
-
,
, ,
,

.
,



, .
:

.
:
-
15

.
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. ,
.

().
( ).
, .
(,
..), ,

,
.

.
, , .
15
- 8 7 ,
14 37 . 20 .
6 ,
9 -.

,
.

.
,
Aguilion
16 ( Toshiba Medical Systems Corporation, ).

(0,5 ).
,

() ( , , ).
,
10-20- , 1- , 5-
( )
.
(3D)
Vitrea. ,

,
,
.
, ,
. ,
.
- ,
. ()
(),
.

.
:

,

,

.
.
:



.


(
, ,
, , ),
,
-
.

(-)
.

.., ..
[email protected]
, ,
,
() (): ..., ..
MODERN APPROACHES TO TREATMENT OF LONG TUBULAR BONES
FRACTURES IN CHILDREN APPLICATION OF METHOD
METALOSTEOSYNTHESIS
Jongo F.A.,,Misago J.V.
Peoples' Friendship University of Russia, Russia, Moscow
The Faculty of Medicine, Department of paediatric surgery
Scientific Adviser(s): Prof. Bychkov.V.A ., Ph.D.
Keywords: metalosynthesis
:
:

.

.
: 5

6
,
.

( )

.


( 24
). , ,
1,5 ,
, .


.
.
.
,
.
:
(, ,
),

.

, ,

 . , , , 2011 | 123
,

.
: , , ,
,

.

..
[email protected]
,
,
,

() (): ..., ..

QUESTIONS OF PARATHERAPEUTIC PATHOLOGY ARE IN SURGICAL

PRACTICE
Zharylgapov M.M.
Karaganda state medical university, Kazakhstan, Karaganda
Medical faculty, Department of pathological anatomy and judicial
medicine
Scientific Adviser(s): Tusupbekova M.M., Ph.D.
Keywords: analysis, estimation and reasons of paratherapeutic
pathology in surgery
: ,

Abstract: In connection with successful development of medicine large
actuality is acquired by perfection of clinical diagnosis, and similarly
questions of quality of providing of medicare. The new problems related
to the estimation of paratherapeutic pathology appear thus. Last years,
among important problems there is a height of paratherapeutic
pathology in the structure of morbidity and death rate of patients. From
data of different sources frequency of paratherapeutic pathology from
data of sectional material hesitate from 1,2 - 36,3 %.
.

,
. ,
.

10-
. -10,

.
1,2 %
36,3 % ,

,
.
,
,
,


,
, .
:
,
.
:

. 2008
2011 .
:

..

, ,
.

,
,

(,
,
,
).
: 1)
, ,
; 2) ,
; 3)
(, ..); 4)

; 5)
(
,
, , ..); 6)
, ,
; 7) ; 8)
,
; 9)
.
, , . .


.
.

, ,

,

. ,
:
;
;
,

, ,
, ,
.
,
,
, .

..
[email protected]
, ,

,
() (): ... ..
ENDOLYMPHATIC PHOTODYNAMIC THERAPY IN TREATMENT OF
PATIENTS WITH SECONDARY LYMPHOSTASIS LOWER EXTREMITIES
AGAINST A BACKGROUND OF RECURRENT ERYSIPELATOUS
INFLAMMATION
Zvezdilin E.L.
Samara State Medical University, Russia, Samara
The Medical Faculty, Department of hospital surgery
Scientific Adviser(s): Zhukov B.N., Ph.D.
Keywords: photoditazin, endolymphatic, photodynamic, therapy,
lymphostasis
: , ,
, ,

124 | III
.


.
, 12-17 %
.

.
.

,
,

.
.

,
: , ,
,
-.
,

.
.

.
,
.

,
-

, 36 .

3 .
.

4,5 6,0 , 1,5
2,5 ,
0,5 1,3 , 0,2 0,4 .

L- ,

, ,
.


( 3-5 ),
, ,
.
.

,

; .

.., ..
[email protected]
, ,
,

() (): ..., ..
ACUTE INFLAMMATORY DISEASES OF TESTES IN CHILDREN
Kiselev E.A., Korochkin M.V.
Peoples' Friendship University of Russia, Russia, Moscow
The Faculty of Medicine, Department of Hospital Surgery with Pediatric
Surgery Course
Scientific Adviser(s): Prof. Bychkov.V.A ., Ph.D.
Keywords: acute, inflammatory, diseases, testes, children, gidatida,
injuries

: , , , ,
, , ,
Abstract: Acute inflammatory diseases of the testes in children is the
second largest acute surgical pathology following acute appendicitis.
According to our data for the period from 2005 to 2010 the most
common is the gidatid torsions. The results of treatment are inversely
related to age, time and degree of torsion. Therefore acute
inflammatory diseases of the testes in children require prompt diagnosis
and adequate treatment.


.

20%
.
:
. :
1. .
2. .
3. .
4. .
. :
1. .
2. .
3. .
4. .


.
. 528
2005 2010 .. (92,41%)
.
, ,
.
.
60-90 %
,
.
454 (85.9 %) 4
15 ,
45 (8,52%)
28 (5.3%)
21 (4,3%) .
, :

,
.
,
.
.

, .
,
, ,
, ,
.


..
[email protected]
, ,

,
() (): ... ..
INTERMITTENT PNEUMATIC COMPRESSION IN THE TREATMENT OF
PATIENT WITH SECONDARY LYMPHOSTASIS LIMB
Myshentsev P.N
Samara State Medical University, Russia, Samara
Medical Faculty, Department of hospital surgery
Scientific Adviser(s): Myshentsev P.N., Ph.D.

 . , , , 2011 | 125
Keywords: pneumatic compression, lymphostasis, fibrosis, sample
McClure-Aldrich
: , , ,
--
. ,

,
.

,
.
.

.
.
40 I-III
. 24 ,
16 . 1 12 , 2 24, 3 -4 . 9
, 31- .
:

: , /3 , /3 , /3 )

--


PULSTAR S2, 9- ,

.
PULSTAR S2. .
80 120 . . .

2-
, .
. ,
,
,
.

,
.
.
.
, , .
,
.

,
,
.
:
1.7-2.5 (1 2.5, 2 2 ,
3 1.7). 1 2.

:
,
(
).
-
2 ( -1-3 ,
- 7- 10 )
.
,

I-III
,
( , ,
), -
, .

.., .., .., ..
[email protected]

.. -, ,
,

() (): ..., . .., .
.., ..., . ..
PATHOGENETIC TREATMENT OF PATIENTS JAUNDICE BENIGN GENESIS
WITH APPLICATION METHODS IMMUNOCORRECTIVE METHODS
Orlova M.S., Luchikhina M.Y., Sheglova K.Y., Hrabraya A.A.
Krasnoyarsk State Medical University named after Professor V.F. VoynoYasenetsky, Russia, Krasnoyarsk
The Faculty of fundamental medical education, Department of general
surgery
Scientific Adviser(s): Professor Vinnik Y.S., PhD, Dyabkin E.V., MD,
Dunaevskaya S.S., PhD
Keywords: obstructive jaundice, drug glutokosim, haematological
parameters, liver enzymes, immune status.
: , ,
, ,
Abstract: Jaundice is a life-threatening condition that develops as a
result of disturbing the natural passage of bile from the liver bile ducts.
The most frequent reasons - gallstone disease, malignant tumor. In this
context, relevant questions remain parallel study of the immune
traditional pathogenetically substantiated therapy of patients with
obstructive jaundice.
,

. (29,2%), (67,3%).


.

.
, ,
,
.


.
:
,

.
:
109
,
.


,
,
-
, .
, 52 ,
(), 1%- 1,
, , 5 .
,
:

126 | III

; .
:
,
1-

.

. ,
. 1-

.
.
3,5;
4 .

, 23,674,14 .
,
, 54,013,24.
-
.
- -
, - -
.
- -
. -
10%,
3%.
:

,
,
,

.

.., .., .., ., ..
[email protected]

. .. , ,

() (): ... . .., ...
.., ..., ..

ANALYSIS OF EARLY AND LONG-TERM RESULTS OF LAPAROSCOPIC

SURGERY IN PATIENTS WITH COLORECTAL CANCER
Sazhin A.V., Lebedeva Yu.N., Mosin S.V., Tyagunov A.E., Volenko I.A.
Russian State Medical University. NI Pirogov, Moscow, Russia
Department of General Surgery, Faculty of Pediatrics
Scientific Adviser(s): prof. Sazhin A.V., PhD, assistant Mosin S., MD,
associate prof. Tyagunov A.E., MD
Keywords: laparoscopic surgery, colon cancer, endovideosurgery
: , ,

Abstract: In the department of general surgery 4 Municipal Clinical

Hospital in Moscow has gained experience in treating patients with
colorectal cancer using laparoscopic technology. From 2004 to 2010
about colorectal cancer operated on 52 patients. Distribution of patients
according to stage of disease at DUKES: Stage A - 12 (23%) Stage B - 26
(50%) Stage C - 7 (13,5%), stage D - 7 (13,5%).Our experience with
laparoscopic technologies in the treatment of patients with colorectal
cancer suggests reducing the number of complications in the early
postoperative period, reducing the need for analgesics, the
implementation of the early activation of bowel function, shorter
hospital
stay.

4 .

.
. C 2004 2010
52 .

COLOR ( 2009 .)
( 2006 .).
71 . 62,5 %;
37,5 %.
DUKES: 12 (23%) ; 26 (50%);
7 (13,5 %), D 7 (13,5%).
:
42 (80,8%), .. 16 (30,8%),

23
(44,23%);
3 (5,77%),
7 (13,43%).
.
.
10 (19,23%) ,
1(1,9%) .
202,327,2 (
120-340 ). 94,23%
2- ,
5 .
3,75 .
14,2 .
1-3 .
87,5%.
75%.
30,8%.
.


, ,
,
.

,

.

,
-
.., .., ..
[email protected]
. .
, ,
,
.
() (): . ., ... ..
FACTORS INFLUENCING A LETHAL OUTCOMES AT PATIENTS WITH A
HEAD WEAPONS-GUSHOT WOUND
Sasunova T.V..Gurkina .. Azami. J.S
Donetsk National medical university of a name of M.Gorkogo, Ukraine,
Donetsk
The Faculty of Medicine, Neurosurgery and otolaryngology chair.
Scientific Adviser(s): Vashchenko A.V., MD
Keywords: weapons-gunshot wound to the head, statistics,
neurosurgery, death, injury, vulnerating projectile
: - ,
, , ,
Abstract: Statistical comparison of groups of patients with a head
weapons-gunshot wound is spent. Results of research allow to draw a
conclusion on absence of statistically significant communication
between a lethality and time from the moment of a trauma till the
moment of rendering of the specialized neurosurgical help, a kind and
an appendix place vulnerating projectile a shell.

 . , , , 2011 | 127
:

,
.
.
(38 ) - ,


1997. 2010 .
Statistika, MedStat.

,

, . .
.
,
2.
.
: 12
12
, .
(
=0,57).
,

, 12 ,
24,0 8,5%, 12 7,77,4% .
(p=0,412).
95% .

18,28,2, 18,89,8,
(p=0,706).

: - 13,38,8, - 22,213,9,
0, - 27,313,4.
2 (p=0,660).
. ,
,

-

, ,
. ,
, n=75
, 80%
5% .

,

..
[email protected]
, ,
, -
, ,

() (): , ..., ..
TELA, AS A CAUSE OF DEATH AT TRAUMATOLOGIC AND ORTHOPEDIC
Sveklonikova O.E.
Peoples' Friendship University of Russia, Russia, Moscow
Medical faculty, Deaprtment of anaesthesiology and resuscitation
science
Russian State Medical University, Russia, Moscow
Medical faculty, Department of traumatology and orthopedics
Scientific Adviser(s): Kondrashenko E.N., MD
Keywords: TELA, traumatologic operations,geparin,preventive
maintenance
: ,
,,

.
,
.
,

64,
5 , .
.
64,
.
.
2009 2005, 2006,
2007, 2008 16
. ,
, 80
; 1,6
2008 , 1,7 2007 , 1,4
2006 , 1,5 2005
. , :
1.
;
2.


( , );
3.
.
,
, ,
.
, 100 %
,
.
:
,

. 2006, 2008 , ,
1/3 -
-
.
( 10
) . 2008
, 2009 1,6
2008 , -

-.
. , ,
,


.

..
[email protected]
,
,
, ,
,
.
() (): ... ..
GENERAL FEATURES OF THROMBOEMBOLIC COMPLICATIONS OF
PATIENTS WITH TOTAL HIP REPLACEMENT
Semyanskaya A.G.
Russian State Medical University, Russia, Moscow
Medical Faculty, Chair of Traumatology, Orthopedic surgery and Military
Medicine
Scientific Adviser(s): Kopenkin S.S., PhD

128 | III
Keywords: medicine, traumatology, thromboembolic complications
: , ,

Abstract: The purpose of the work - improving methods for prevention

of venous thromboembolism in patients undergoing hip replacement.
96 patients (47 with fresh fractures of the femoral neck - 1 group, 49
from deforming coxarthrosis and false joints of the femoral neck - 2
group) was performed hip replacement. In the preoperative period all
patients underwent ultrasound angioscanning of the lower extremities.

() ,
. 96
(47 1 , 49

)
.

() . 1
23 , 14 , 1 , 9
. 1
17 (36,2%), 2 - 2(4,1%) . ,
,
,

. , ,
.

..
[email protected]
"
" . , ,

, 1
() (): ... ..
DEMANDING FOR COSMETIC SURGERY AMING THE POPULATION OF
THE KOMI REPUBLIC
Surkova L.I.
Komi Branch of the State Educational Institution "Kirov State Medical
Academy, Federal Agency for Health Care and Social Development " in
Syktyvkar, Russia, Syktyvkar
Medical Faculty, Department of surgical diseases 1
Scientific Adviser(s): Vatlin A.V., PhD
Keywords: cosmetic surgery, Komi Republic
: ,

Abstract: Analysis of 1736 cases for the paid surgical treatment has been
done from 1999 to 2008. A number of patients seeking the treatment
grows in winter. Women are among predominant patients. The ratio of
men and women is 1 to 4, and the average age of patients is 33. The
most common causes to seek the treatment are skin and subcutaneous
fat tumors, aged changes of face skin, nose deformity, postoperative
scars.

,
. - ,
.
:


:
(..) 1999 2008 (n=1736).
:
1. .
2. ;

3. ;
4.
, , ;
:
1.
(-).
-, ,
;
2. 80%, 20%.
33 .
9 , - 72 ;
3. . ..
21% ,
17%, 13%,
, 16%, 7%,
6%, 4%,
3%;

, .
4.
(17%),
,
(16%), (12%), (11%)
(9%).

17%, ,
18%, 13%.
27%, 15%,
13%.

.., ..
[email protected]
. .. , ,

,
. ..
() (): ..., ..
ANTIOXIDANT CORRECTION OF FREE RADICAL OXIDATION PROCESS IN
OBSTRUCTIVE CHOLESTASIS BY INTRAVENOUS AND INTRAPORTAL
INFUSION
Hvostunov S.I., Arapov A.S.
N.P. Ogarev Mordovian State Universiti, Russia, Saransk
Medical Institute, N.I. Atyasov Department of General Surgery and
Anesthesiology
Scientific Adviser(s): Belyaev A.N., PhD
Keywords: obstructive cholestasis, intraportal infusion, lipid
peroxidation, mexidol, liver
: ,
, , ,
Abstract: Introduction of infusion of saline does not lead to the
correction of free radical oxidation. Intra-portal route of administration
of 5% solution of mexidole is superior to intravenous route, due to a
high concentration of drug in target liver tissues.
.
,
.
.


.

() ,


.

 . , , , 2011 | 129
. (/)
(/) 5%

.
. 30
8 36
. / (45
/ )
. 1 (n=10) ,
/
20 /. 2
(n=10) / 5% . 3
(n=10) / 5%
. 4
.
. 3

(),
(), ()
40,6; 10,9; 23,1 , 9
, 2,1
. /
295,524,74
81,2529,65 /; 2,350,12 0,740,11
/*; 4,050,29 1,350,07 /*,
23,373,71 29,272,41 /,
16,960,81 13,711,4 /.
/ 5%
9,890,65 /; 0,330,14 /*;
0,660,25 /*. 39,234,6
/, 10,290,73 /. /
5% 5,400,71
/; 0,270,02 /*; 0,340,12
/*, 46,995,09 /
7,310,9 /.
. 1.
,
.
.
2. 5%


,
,
.

..
[email protected]
, ,

,
() (): ... . ..
EXTRAVASAL CORRECTION VALVES OF DEEP VEINS OF LOWER
EXTERMITIES
Tsygleev S.G
Samara State Medical University, Russia, Samara
The Medical Faculty, Department of hospital surgery
Scientific Adviser(s): Katorkin. S.E., PhD
Keywords: varicosity, extravasal correction, valves
: , ,

Abstract: Introduction of infusion of saline does not lead to the

correction of free radical oxidation. Intra-portal route of administration
of 5% solution of mexidole is superior to intravenous route, due to a
high concentration of drug in target liver tissues.
.

.

,
15-30% .
,
35 . .

. ,

- , ,
.

.
.


.
.
62 ,
C2 C4, CEAP.
: ,
, .

.

.
, ,

.
CIVIQ,
.
.
1.
( 62 100%)
62-

,
, , .
2. ,

,
.
.

,
.

.


,

CIVIQ.

.., .., ..
[email protected]
, ,
,

() ():..., ..
COMBINED OZONE AND LASER THERAPY IN THE TREATMENT OF ACUTE
PYELONEPHRITIS
Zakhidov U.M., Muminov D.B., Sushentsov M.V.
Peoples' Friendship University of Russia, Russia, Moscow
The Faculty of Medicine, Department of Urology and operative
nephrology
Scientific Adviser(s):Professor, Dr. Avdoshin V.P.

130 | III
Keywords:acute pyelonephritis, ozone therapy, low intensity laser
radiation, intravenous laser irradiation of blood
: , ,
,


, -

.
168 , .
35,25,3 .
.
53
,

.
63
,

,
,
().
52
,
,
(),
().


2- .

(Ri) (Pi) ,
.



2- , (Ri)
(Pi). I 2-
: 2090 \, 1650
\, 11 310 \. II
2- :
4230 \, 2870 \,
13 280 \. III
2 : 6560 \,
3790 \, 17
305 \. I (Pi) :
1,440.08, (Ri) 0.760.08,
9
(Pi) 1.180.03, (Ri)
0.540.02. II (Pi) :
1.520.05, (Ri) 0.780.04,
7
(Pi) 1.150.02, (Ri)
0.520.03. III (Pi) :
1.560.08, (Ri) 0.780.06,
9
(Pi) 1.160.02, (Ri)
0.530.03.
,

,
- ,

,
-
,

.
( )

.. , ..
[email protected]
, ,
,
() ():, ... ..
INFLUENCE OF A HOSPITAL INFECTION ON A CURRENT OF DISEASE AT
PATIENTS WITH A DESTRUCTIVE PANCREATITIS
Sadovnikova E.U. , Bycika E.I.
Peoples' Friendship University of Russia, Russia, Moscow
The Faculty of Medicine, Department of faculty surgery
Scientific Adviser(s):Ph. D. Korolkov A.U.
Keywords:Pancreatitis, hospital infection, activators, bacteria, plasmids
: , ,
, ,
,
- 2-30%
,
3,5 80% (2,5,8). - ,
- .
85%
(2,5).
,

- ,
(3).
, -
, -
.

-,

- ,
-(3,6,7).
:

.
.

64.
2009 2010 .
44 ,
13 (29,5%) -
.
31 (70,4%) ,
-
.
(, , , ,
- , )
-
.
Lachema,
Labsystem iEMS Reader -2.

-.
.
,
- ,

.
() ,
, .

13,37 .
() ,
,
.

 . , , , 2011 | 131
,
, - 50
-.
18 (40,90%)
. 9
(11,42%) -.
II 12
(27,27%), 22 (20,45%)
.
-,
- 30
, - 50%.

- APACHE II .
12 (57,14%)
15-19 APACHE, 4
(19,04%) 20-24 , -
.
.
11 (47,82%),
,
7 (30,43%) -
.
(8,69%),
, -

. -
,
-
, - .

(29%) , 16%
- .
(28%) - .

. 8%,
- 20% .

15% .
22 (9,68%)
, .
-: 17
(38,6%)
, 4 (9,09%)
- , 1 (2,27%)

-
.

( , , , , ,

- .
96
, - 123 ,
56 , 87 ,
37 .
.
, ,
, ,
, -

.
56%
, 8% - - - .

(28%), 13% .
,
- .

- ,
100%
() 90%
, , .
b- ( I-IV
) .

-.
, -
.
,
-
.
:
,
, ( APACHE II) ,

- : Klebsiella pneumoniae,
Pseudomonas aeroginosa, E. coli, Acinetobacter spp., Staphylococcus
aureus.

, .
:
.. // .: , 1976.-223 .
.., .., ..//


.- : , 1987.- 134.
..
// Terra Medica.2002.-4. .41-43.
..
- :
. . . .- , 2000.-26.
.. //
- .- 1996.-2.- .4-9.
.., .., .. .
-:
.//
2000, 2.- .12-16.
Bassi C., Pedersoli P. et al // Antimicrob. Agents Chemother.- 1994.-Vol.
38.- .830-836.
Jarvis W.R. Selected aspects of socioeconomic Impact of nosocomial
infections: morbidity, mortality, cost and prevention // Inf. Contr. Hosp.
Epid.- 1996.- Vol. 17, 8.-. 552-557.
LeClercg R. Plasmid-mediated resistence to vancomycin and teicoplanin
in Enterococcus fa-cium // N.Engl.J.Med.- 1988.-Vol. 319.- P. 157-161.

.. , ..
[email protected]
..
, ,
1,
1
() ():... ..
INFLUENCE OF ECORECESSIONARY FACTORS ON IMMUNOLOGICAL
FEATURES OF AN WOMEN'S ORGANISM WITH A UTERINE
LEIOMYOMA
N.S.Trojan, Y.G.Drupp
Donetsk National medical university named by M.Gorkiy , Donetsk
,Ukraine
Medical faculty 1, chair of obstetrics and gynaecology 1
Scientific Adviser(s):PhD S.N. Tutov
Keywords:ecorecessionary region, immunological features, leiomyoma
: ,
,
Abstract:The aim is to study the leukograms measurement and the
natural killers(NK) count among women with a leiomyoma , living in
ecorecessionary Donetsk Region.
Materials and methods: 75 women 420,7 years old are surveyed. The
leukograms indices analyzed, including the large granulated

132 | III
lymphocytes. The number of NK registered on an expression of antigens
receptors membranes of peripheral bloods lymphocytes by means of
monoclonal antibodies to the cluster of differentiation D3 + and CD16
+. Results processed by variation statistics methods.
Results: the leukocytesaverage number were 5,50,23 g/l, peripheral
bloods neutrophils 6,430,68 g/l, eosinocytes 0,16 g/l, lymphocytes
1,760,2 g/l, peripheral bloods monocytes 0,200,05 g/l. The large
granulated lymphocytes number didnt exceed 0,030,01 g/l. The count
of this lymphocytes pool varied from 0,06 g/l to 0,47 g/l. NKs number
in 15 % surveyed was raised, and at 85 % - it is considerable below
regional norm. The average NKs count among women with a leiomyoma
was one half as high (authentically decreased), making 0,170,05 g/l, at
norm of 0,350,03 g/l.
Conclusions: the leukograms features of peripheral blood at women
with a leiomyoma consisting in authentic increase of a neutrophils pool
are revealed, reduction of lymphocytes pool and NK of peripheral
blood that testifies and confirms a role of decrease in nonspecific
resistance in development of a leiomyoma in women ecorecessionary
Donetsk Region, and needs additional researches and working out of
adequate methods of immunocorrection .
:
,
.
: 75
42+0,7. ,
.


D3+
CD16+.

,
CD4+, CD8+, F(ab'), ,
.
.
: 33%

.
5,5+0,23/, - 5,16+0,09/. 22 %

, 44% .

6,43+0,68/,
2,82+0,8/ (<0,05) 1,46 / 7,03 /.
,

,

.
0,16/,
0,08+0,01/. 33
%
, 11% - .
0,10/ - 0,34/. ,
, 1,76+0,2/ - 2,24+0,09/,
1,15/ - 2,87/.
33%, 11%
.
.

0,20+0,05/,
- 0,09+0,01/.
0,05/ 0,46/.
22% .
0,03+0,01/, 0,06+0,01/,
(P<0,05) ,

. ,

.
0,06/ 0,47/. 15%
, 85% -
.

(
), 0,17+0,05/, 0,35+0,03/.
:
,
,
,


,
.

.
.., ..
[email protected]
, ,
,

: . . ., . .
THE EVALUATION OF NONSTEROIDAL ANTI-INFLAMMATORY DRUGS
EFFICACY IN POSTOPERATIVE PAIN CONTROL IN TRAUMATOLOGIC
AND ORTHOPEDIC SURGERY .
Abdrakhmanov R. R., Danilov M.
Peoples' Friendship University of Russia, Russia, Moscow
The Faculty of Medicine, Department of Anesthesiology & Intensive
Care
Scientific adviser: associate professor Kondrashenko E. N.
Keywords:postoperative pain syndrome, nonsteroidal anti-inflammatory
drugs, narcotic analgetics
: , ,

Abstract: This study aims to evaluate the analgesic efficacy of
Nonsteroidal Anti-Inflammatory Drugs such as Dexketoprofen (Dexalgin
25 mg) and its effect on the need for opioids in the postoperative stage
of traumatologic and orthopedic surgery.

. ,
-2
.

.

(
per os)
.
. 70
, 4 . 1
(15 ) ,
;

/ 50 12
, 3
() 25
8 .
50 /. 2 (15 ) ,


( 20 /). 3 (20
) ,

() 25 8 . 4
(20 ) ,
(
20 /).
.

 . , , , 2011 | 133
. 1. ,
. 2.
- ().

(
)

, 2, 4, 6, 8, 12, 24, 30, 48,

54, 72, 78, 96, 102, 120 , .
. 1 ,
( 6 ),
(11 )
() ,

.

/: 50-10 (4 ), 150-250 (4 ),
250-400 (3 ).
25 3-5 1
:
.

2 3-4
20 .
5 1-2
.
3 (
6 ),
16 . 4
/ .
4 / 2-3
20 1 1-2
2 .
70
.
.
1) 25 (3 )

.
2) ,
()
,
.
3) ()


.

. ., . .
[email protected]
""

3
: .. . .
DIAGNOSTIC AND SURGICAL TREATMENT OF RETROPERITONEAL
LIPOMS AND LIPOSARCOMS
Abdullaeva A. A., Gvarishvili M. A.
Federal Governmental Organization Russian Scientific Center
Rentgenradiologiy Rosmetekhnologiy
3rd surgical department
Scientific Adviser: Doctor of Medical Science, Professor Chikvadze V. D.

Keywords: lipoms, liposarcoms, retroperitoneal space, oncology

, ,
:,
Abstract: The thesis is devoted to specifics of surgical treatment and
diagnostic of lipoms and liposarcoms. Specifics of these tumors are:
large sizes of nodules, multinodular forms of development and other
which are not allows to perform radical surgical incision of this tumors.

.
( )

.
:
.
. 1995
29
, 17 77 .
5 : 3 , 2 - .
24 : 16,
8. 5 9

. 6
, 3 .
21 ( 24) 33
. 25
,
4 -
, 3
5 .
3 - .

. 3
.
3 :
,
,

,
- 1 ;
1 , 1
.
2 : ,
,
-

.
2 10 7,5
,
. 12
10 ,
. 2
.
8 . 12 10 .
3 . 3,5 5 ,
4 . 10
2 , 3 3 , 5 3
10 2 .
:
: ,

,
,
. ,
,
, ,
.

, .., .., ..
[email protected]
20 .,
,

:... , ... .., ...
..
THE OZONOTHERPY AND TAMSULOSINTHERAPY IN COMPLEX
TREATMENT OF A CYSTITIS.
Avdoshin, Borisov V.V., Smelyakov V.A., Lebedeva R.P.
City Polyclinic 20, Russia, Moscow
Urology Branch
Scientific Advisers: Ph.D. Avdoshin, Ph.D. Borisov V.V., Ph.D.lebedeva
R.P.

134 | III
Keywords: Cystitis, ozonotherapy, samsulosin, disauria,bacteriuria, an
alpha-adrenoreceptor, an alpha-adrenoblokator, fluometria
: , , , ,
, -, ,

Abstract: Cystitis remission in stages of an aggravation and

disappearance of clinical displays with reduction objective urodinamic
indicators according to questionnaires-IPSS and urination diaries is
received at use ozonotherapy (10 sessions at intravenous introduction)
in a combination with tamsulosin unlike control group of patients (20
persons), receiving only antibacterial treatment.

.

, -
,
.
,

.

.
-,
,
.

.
(20 )

4 10
0,4 .
(20 )
.
(20 )


.
,
( , ,

),

3 ,
, ,
IPSS QoL
.

(80-85%) (74-80%), 7477% , B.coli (6580%), Staph.spp. (33-40%), Proteus (27-30%), Clebs. (16-20%), Enterocc.
(10-13%), (3-5%).
100%
, 75% (P<0.01).
60-67% ,
52%
(P<0.05).

, 75-77%
, ,
48% (P<0.05).

,
,
,
.
IPSS
,

.
,

.

,
.

,

.

.., .., ..
[email protected]
, ,
,
: ... ..
ENDOSCOPIC RESECTION OF STOMACH POLYPI
Babaian S.A., Shemyatovsky K.A., Zolina E.S.
Peoples' Friendship University of Russia, Russia, Moscow
The Faculty of Medicine, Department of Faculty Surgery
Scientific Adviser: Ph.D. Lebedev N.V.
Keywords: endoscopy, polypectomy
: ,
Abstract: The problem of current concern today is the choice of optimal
stomach polypi treatment. In this work the advantages of radiowave
resection over electrosurgical method in endoscopic operations are
considered.
10%
- ().
,
, , .
, . ,
,
.

.
.
.
3% ,
88%.

.

.
3 5
.
5 , , ,
-.
,
.
-
, 40
, . 2001 .
2010 .

64 . 174
, , 162
. 174 164
10 .
5311,3 , 134 28 (1:0,2).

. (94 )

. (68 )
( Surgitron).

40 .
5,5 (75 ).
,
24-72 , 10 (6,2%): 9 (9,6%)
1 (1,5%)

 . , , , 2011 | 135
,

.
76
, 19 , 2
- 1 .
63
, 10 , 1 -, 2
.
,


.

.

.
.., .., .., ..
[email protected]
, ,
,
: ... ..
APPLICATION OF HEMOSTATIC GLUE IN RHINOSEPTOPLASTY FOR
OPTIMIZATION OF THE POSTOPERATIVE PERIOD.
Berezova D.K.,
Bitsaeva A.V., Grishina A.S., Karavaeva O.Y.
Peoples' Friendship University of Russia, Russia, Moscow
The Faculty of Medicine, Department of otorhinolaryngology
Scientific adviser: M.D Popaduk
Keywords: Deformation of the nasal septum, rhinoseptoplasty, final
stages of a surgical intervention, fixation of the nasal septum in the
middle position, tamponade of the nasal cavity, hemostatic glue,
intranasal structures, reactive phenomenon
: ,
,
,
, , ,
,
Abstract: Deformation of the nasal septum is the most common disorder
in ENT practice. In most cases, require surgical treatment. Surgical
intervention entails a number of complications (perforation of the nasal
septum, the formation of adhesions, hematomas of the nasal septum).
To prevent them surgeons use various techniques of mechanical fixation
of the nasal septum in the middle position, but they have obvious
disadvantages.
In turn, the use of hemostatic glue in the final stages of rhinoseptoplasty
provides optimization of the postoperative period in patients with
deformations of the nasal septum.
~ 80 %
, 20%
,

.


.

:
, , .

,
. ,


,
, - 4 .
.

-
, 1
,
. 5
,
6-8 .

. .

,
. .

. .
35
.
(70 ) .


( ,
.)
(
).

95%
3 ; - 34 ;
2-4 .

5 (14%);
;
.
,
, , ,

.., ..
[email protected]
, ,
,
: ... ..
OPEN TALUS DISLOCATION
Bondarenko P.V., Tkalin A.N.
Peoples' Friendship University of Russia, Russia, Moscow
The Faculty of Medicine, Department of traumatology and orthopedy
Scientific adviser: M.D. Lomtatidze E. Sh.
Keywords: Open, Talus, Dislocation
: ,
Abstract: This case review open total talar dislocation, the subsequent
development of infection and avascular necrosis of the talar
dome, and the clinical and functional outcomes associated with this
injury. Open total talar dislocation is a relatively rare but debilitating
injury. Techniques for managing such injuries include reimplantation of
an extruded
talus, open reduction internal fixation, and fusion (immediate or
delayed).

. .. .

.
, ().
: N 36 3 , .
, ,
, .
,
. , .

136 | III

, 63

.
90 . ,
.
.
. . ,

. .
. 12
.
.

. 8

6 . 14 .
. 5
.
3 .
.
(Wagner, et al. 2004)

.

, - -
. 3/5
.
, .
, -
. 75%


( ).

. , ,
, .



.

, ,
.
(J.Schatzker, 1994) ,
. ,

(
),
( - )
.
, ,
, ,
.
,
.

.

,
-
.

. ,
20%
, 30% 16%.

.

- .

.. , ..

[email protected]
, ,
,
L ... ..
TACTICS OF TREATMENT OF PATIENTS WITH GASTRODUODENAL ULCER
BLEEDINGS
Bycika E.I. , Sadovnikova E.U.
Peoples' Friendship University of Russia, Russia, Moscow
Medical faculty, Department of faculty surgery
Scientific Adviser: Ph.D. Lebedev N.V.
Keywords: Ulcers, bleedings, a hemostasis, therapy, operative
interventions
: , , , ,

Abstract: to work out technique of treatment of patients with
gastroduodenal ulcer bleeding (UGDB) based upon the definition of the
rebleeding occurrence and the objective estimation of the severity of
the patients health status.

.
,


.



.
? ,
?
, ,
,
.. .
(, )
- ,

(
),
. ,
(510%
*5+, -
.

*1,3+.
,
,
, .

.

.
.
(
) ,

.

.

.
,

*2+.
, ,

.

 . , , , 2011 | 137

[1].



, ().

,
,

. ,

,
,
.
2008
SAPS II ,
, ()
() *4+.

- ,

.


21


, 80
8 / ,
, .

- Forrest-IA IB (
) .
:

Forrest-IIA, IIB ( 21 )
30 SAPS II.
30
SAPS II

.

(
- , ).


.
2007
. 336
.
11,2%.
2,8% ( 6 213),
27,8% ( 35 123).

(, ,
.).
(2,9%).

.

1.
.., ..
(, , .
-, 2008, 384 .
2.
.., .., .., ..,
..

// 2002 - 3 - . 83-85.
3.
.., .., ..
-
:

// 4 2004, 8-12.
4.
.., ..
// ; 2009; 2: 33
37.

5.
Stiegmann G.V. Endoscopic approaches to
gastrointestinal bleeding. //Am. Surg., 2006, 72(2): 111115.

upper

. .
[email protected]
, ,

,
: . .

PECULIARITIES OF SURGICAL TREATMENT OF PURULENT - NECROTIC

FORMS OF DIABETIC FOOT
Elmiheeva A. S.
Orenburg State Medical Academy, Russia, Orenburg
The Faculty of Pediatrics, Department of General Surgery
Scientific adviser: Assistant of the Department of General Surgery U. P.
Belozertseva
Keywords: diabetic foot, neuropathic, neuroischemic, amputation,
primary intradermal suture
: , ,
, ,

Abstract: This work is devoted to the study and analysis of methods of

surgical treatment of purulent - necrotic forms of diabetic foot
syndrome at the original plastic total-skin grafting and the imposition of
a seam on the intradermal drainage - flushing the system with
retrograde catheterization of the arteries.
XXI
. ,
.

,
. (. ..

"" "",
2005 .




.
:

.
792
,
. 1998 . 2009 .
27 82 .
.
,
(55%) (33%)
(12%).
-
493 . 33
; 63 ; 397
.

.
57 %

,
,

, .

:
;

138 | III
.
,
.


.

.
,
.
-
.
,
,

.
.
,
, -


( 15 -), (11,2 %
) ( 3 %
).
,
-
.

.

,

.

,
:
SHOCK.
..
[email protected]
-

EARLY REVASCULARIZATION PROVIDE A LONG TERM SURVIVAL
BENEFIT IN PATIENTS WITH CARDIOGENIC SHOCK COMPLICATING
ACUTE MYOCARDIAL INFARCTION : FOLLOW UP RESULTS IN SHOCK
TRIAL.
Zhavoronkova I.A.
Moscow State University of Medicine and Dentistry
The faculty of medicine
Keywords: cardiogenic shock complicating acute myocardial infraction,
early revascularization, medical measures.
: , ,
.
Abstract: The paper analyzes todays concepts on the cause of early
revascularization provide a long-term survival benefit in patients with
cardiogenic shock complicating acute myocardial infraction. It considers
the medical measures, new strategies. Key words: cardiogenic shock
complicating acute myocardial infraction, early revascularization,
medical measures.
( )
( ),

(
). ,
( )
.

,

.
2492 ,
229. 225
, .
. 124
(55,4%) 101 (44,5%).
() 62,8 , () 70,8,
() 66,4.
: 34 (15,2%),
59 (26,1%),
21
(9,2%), 30
(13,3%),
53
(23,5%), 15
(5,6%), 13 (5,9%).
190 (84,4%), 35 (15,6%).
4 79
(35,1%), 6 105 (46,7%),
8 118 (52,4%), 24 132
(58,7%), 48 144 (64%),
72 159 , 53 (23,6%).
:
;
()
;
; 80 15 3;
;
;
;
;
;

;
. 1

.
: 80100 3 12 (5,3%), 100-140 3 80 (35,6%),
140-180 3 64 (28,4%), 180-200 3 28
(12,4%) . : 20-35 3 32
(14,2%), 35-55 3 56 (24,9%), 56-70 3 44
(19,6%), 71-80 3 21 (9,3%), 81-90 3 15
(6,7%), 91-100 3 12 (5,3%), 100-120 3 20
(8,9%), 121-140 3 7 (3,11%), 141-160 3 5
(2,2%), 161-180 3 13 (5,8%), 181-200 3 7
(3,1%).
: 30-40 3 12 (5,3%), 41-50 3 4
(1,8%), 51-60 3 13 (5,8%), 61-70 3 44
(19,6%), 70-100 3 125 (55,6%), 101-120 3
15 (6,7%).
: 20-30% - 16 (7,1%), 31-40% - 24
(10,7%), 41-50% - 44 (19,6%), 51-60% - 52 (23,1%),
61-70% - 65 (28,9%), 71-80% - 23 (10,2%).
: 2,5-3,5 /. 18 (8%), 3,64,5 /. 40 (17,8%), 4,6-5,5 /. 54
(24%), 5,6-6,5 /. 62 (27,6%), 6,6-7,5/. 26
(11,56%), 7,5 /. 25 (11,1%).
. 229
84 (36,7%), 145 (63,3%), 42 84 ,
68,6 . 128
(56,1%), 101 (44,0%). :
123
(53,7%),
40 (17,3%),
33 (14,5%),
- 22 (9,8%),
11 (4,7%).


, , ,
:
136 (60,4%), 66
(29,3%), 23 (10,2%).
:

 . , , , 2011 | 139
60%, 70 3, , , ,
.
: ,

. , ,
,
, .

:
,

..
[email protected]

.., ,
, ,

: ... ..
ESTIMATION OF PERCUTANEOUS VERTEBROPLASTY AS A TREATMENT
FOR COMPRESSION FRACTURES OF LUMBAR VERTEBRAL BODIES ON
THE BACKGROUND OF OSTEOPOROSIS IN ELDERLY PATIENTS.
Zharikov Y.O.
I.M. Sechenov First Moscow State Medical University, Russia, Moscow
The Medical Faculty, Department of Traumatology, Orthopedics and
Surgery Disasters
Scientific adviser: Ph.D. Cherepanov V.G.
Keywords: Percutaneous Vertebroplasty, Osteoporosis, Minimally
invasive method, Vertebral compression fracture
: , ,
,

Abstract: Compression fractures of osteoporotic lumbar vertebral bodies

represent a huge medical and socio-economic problem. The prevalence
of vertebral fractures in people with osteoporosis in Russia averaged
11.8%. Minimally invasive procedure, such as vertebroplasty is wellestablished minimally invasive treatment options for compression
fractures of osteoporotic vertebral bodies. Vertebroplasty is effective
technique for the relief of back pain in patients with osteoporotic
compression fractures.


-
.

, ,
11,8% (14,5% 10%
).
6 , .

.
(, ).

.
,
, ,

.

.
: 24 ,
2010
2011 .; 9 (37,5%) 15 (62,5%).
68 2 ,
64 70 ; 71 2 ,

69 73 ).

.

.

,
.
, 7 ( 29,2% )
LI, LII
(1), 17 ( 70,8% ) LII, LIII (2),

Magerl.

( - 2).
,
, .
.
.
.
;
41,5 .
:
397
(14-55 ). 21 (87,5%)
, 3 (12,5%)
1 score on the Pain Score scale,
1-2 .


.
:

,
,
,

.


,
.

.., .., ..
[email protected]
..

,
: ... .., ... ..
QUALITATIVE CHARACTERISTICS OF THE LAPAROSCOPIC
CHOLECYSTECTOMIAS
Zvyagintsev V.V., Gorpinyuk V.P., Fomov G.V.
Transnistrian state university of name .G. Shevchenko
Medical faculty, urgery department
Scientific adviser: Ph.D. Stavinskii R.A., Ph.D. Chalyk J.V.
Keywords: laparoscopic cholecystectomia, characteristic, classification.
: ,
, .
Abstract: Research is based on rich clinical experience of authors 2948
laparoscopic cholecystectomias (LCE) within 14 years. Arguing on
operative treatment, it is necessary to use the accurate scheme allowing
correctly to characterize concrete surgical operation. Authors suggest to
enter a series of qualitative characteristics of LCE for their introduction
into practical, scientific activity, uniformity in value and possibility
qualitatively to describe surgical operation.

140 | III

,
(),
,

.

2948
, ,
Karl Storz, Olympus, , .


: (), ,

(),
,

().
,
. , ,
, ,

,
. ,
, ,
.
,
.
.
- ,
.

,
,

,

,
.
,
,
.

4,35 .

50 .
50,41 .
3,5 6 .

. 3 ,
, .,
.
:
1)

, ;
2)
,
,

,
.
3)
, ,
, ,

().
4)

. ,
III IV .
I II .

.
.., .., .., ..,
. .
[email protected]
..
, , , .

,
: ... .., ... ..
QUANTITATIVE CHARACTERISTICS OF THE LAPAROSCOPIC
CHOLECYSTECTOMIAS
Zvyagintsev V.V., Gorpinyuk V.P., Stavinskii R.A., Fomov G.V.,Chalyk J.V.
Transnistrian state university of name .G. Shevchenko, Moldova,
Tiraspol
Surgery department, medical faculty
Scientific Advisers: Ph.D. Stavinskii R.A., Ph.D. Chalyk J.V.
Keywords: laparoscopic cholecystectomia, characteristic, classification.
: ,
, .
Abstract: Research is based on rich clinical experience of authors 2948
laparoscopic cholecystectomias (LCE) within 14 years. Arguing on
operative treatment, it is necessary to use the accurate scheme allowing
correctly to characterize concrete surgical operation. Authors suggest to
enter a series of quantitative characteristics of LCE for their introduction
into practical, scientific activity, uniformity in value and possibility
quantitatively to describe surgical operation. Classifications, definitions,
terminology, criteria of quantitative characteristics of LCE are offered.

,
,
(),
,
.

,

15 . ,
2948

, ,
Karl Storz, Olympus, , .


,
: , ,
( ).
,

,
. :
(
,
),

,
,
.
.

( )
.

.
-.
, (8 )

- , .
2 - 2,7 -.


, , ,
(, ).

: ( ,
), ,
(
, ),
, ,
.

(44,49 )

 . , , , 2011 | 141
(79,12 ).
,
57,08 .
() - (),

(), , ,
, , ,
. ,
,

-
.
:
1) ,
-.
2)
.
3) , , () ,
,
.

:

.., .., ..
[email protected]
-
. ..

: , ..., .
COMPLEX REGIONAL PAIN SYNDROME: DIAGNOSIS AND TREATMENT
Zolotushkin M.L., Menzorova N.V., Kuznetsova N.L.
Ural Scientific Research Institute of Traumatology and Orthopedics. VD
Chaklin
Traumatology and Orthopedics FPC and PCB
Scientific Adviser: Kuznetsova N.L., PhD., prof.
Keywords: Complex regional pain syndrome, diagnosis, treatment
kriologicheskoe
: ,
,
Abstract: It is offered the pathogenetic surgical approach to treatment
KRBS, including periarterial cryosympadestruction. It is shown high
medicine-social and economic efficiency.

()
(, )
.
,

, , ,
.

,

, ,
, ,
,
.
.

().
. 173
I . ,

,
,
,
, .

, ,
,
.



,
.
,
.

, ,
,
,

7 10 ,
,
.
.


,
.

( .. ),
. 3 7 ,


.

20 .

,
.
2002 2010 .
.
,
, .

..
[email protected]
, ,

,
: ..
MODELING OF PANCREATIC HYPERTENSION AS MECHANISM OF
PATHOGENESIS PANCREAS NECROSIS
Kornaukhov A.N.
Altai State Medical University, Russia, Barnaul
Medical faculty, Department of normal anatomy
Scientific Adviser: Fedina I. Yu.
Keywords: pancreatitis, hypertension of ducts, necrosis
: , ,
Abstract: The acute pancreatitis takes the third place among urgent
diseases of organs of an abdominal cavity. Mechanism of pathogenesis
of this disease till now is the subject of discussion. However there is no
information about directions of diffusion of a pancreatic secret outside
the main duct. So the main purpose of the present research is
experimental modeling of a pancreatic hypertension by introduction in
the main pancreatic duct a contrast agent.
.
,
10-12% (..
., 1998).
1530%

142 | III
15-45% (.. , ..
, .. , 2008).

.
:

, .

.



.
:

.
. 12

, ,

-
(lig.gastrocolica),

.
,
- U- .

, .

. .
.
, ,


.
150,935,6 . .

(10 )
(2 . .

.

.
.
1)
,

,

.
2)

.

KI-67, -9 IV

.
..
[email protected]
, ,
,

: ..,
..
SIGNIFICANCE OF KI-67, MMP-9 AND COL IV IMMUNOHISTOCHEMICAL
MARKERS DETECTION FOR DIAGNOSIS AND PROGNOSIS OF BLADDER
TUMORS.
Kotelnikova E.V.
Peoples Friendship University of Russia,Russia,Moscow
The Faculty of Medicine,Department of urology

Scientific Adviser: Prof.Avdoshin V.P., Prof. Babichenko I.I.

Keywords: urotelial bladder tumors,prognostic markers,
immunohistochemical markers.
: ,
, -

Abstract: The prognostic value of the expression Ki -67, -9 and

collagen IV were estimated in urotelial bladder tumors. The biopsy and
surgery samples from 43patients (27males and 16 females ) aged 42 to
87years(mean age 66 1.5years) who received combination treatment
for urotelial tumors. It has been found that Ki -67, -9and collagen
IV are important prognostic markers of urotelial invasive bladder
carcinoma (BC).

()-

,
.
() 2.8%.

( .., 2006).


,
( )
. .
, ,
.

, -
() ,

.
()
-9 (-9)

.
:
Ki 67, -9, IV
.
43 ,
16 (27%) 27(67%) ,
66 1.5 ,
64 29,

.

-
.


, ,

.

.
Ki-67 3,3+2,5%.

(3,2+2,3)

.
1 16,4+13,5%,
2 - 21,0+7,3%, 3- 41,0+8,5% ,

.
T1; T1-T2 T2-T3 .


,
. ,
,

.
-9,

 . , , , 2011 | 143
IV
.

,
.

... .., . ..
[email protected]
-
. .., 23,
, . .
,,
.
: ..., . ..
CRYOSURGERY IN THE COMPLEX TREATMENT OF THE PAIENTS WITH
PYOINFLAMMATORY OF COMPLICATION DAMAGE FACE AND NECK
Makrova O.A., MD Kuznetsova N.L.
City Hospital 23, UNIITO Rodrav named after V.D.Chaklin.
Ear, nose, and throat emergency centre,
Scientific Adviser: MD Kuznetsova N.L.
Keywords: ryosurgery, damage face and neck,pyoinflammatory
: -
,
Abstract: Local ryosurgery was applied in the complex treatment to the
patients treated in the ENT department.
.
,
,
.



.
. 187

,

.
190

, .

( 1,0*3

/),
,
,

.
.

3 - 4 ,
,
,
.

..
[email protected]
. ..,
,
,
:... ..
MODERN ASPECTS IN TREATMENT OF INTERVERTEBRAL HERNIAS
Ponomarev D.S.
The Tambov state university of G.R.Derzhavin, Russia, Tambov
Medical institute, pathophysiology Chair
Scientific Adviser: The candidate of medical sciences Glotov I.I.

Keywords: The backbone, disease, treatment, hernia, restoration,

conservative, surgical, alloplant to recycle, kinesitherapy
: , , , ,
, , , ,
, .
Abstract: The problem of damage of a backbone involves great attention
of domestic and foreign doctors of various specialities. The new
approach to treatment more and more affirms in process of deepening
of that understanding that use only medicamentous means often
doesn't render by-effects (for example, toxic, allergic). Treatment
methods it is possible will divide on two groups: conservative and
surgical.
Kinesitherapy, or treatment by movement, is not only special and
individually picked up techniques of medical gymnastics, and application
special corrective
poses - treatment by position, but also massage versions, and also
robotized mechanical therapy (walking restoration), training apparatus
of a various orientation (cyclic, power, inertial, rotational, etc.)
Sistem DR9000 , DR9500 . Treatment of hernias of a backbone is
enough challenge. Duration and the treatment form depends on neglect
of disease, the form of a hernia, complexities of each concrete case and
the success of treatment directly depends on individual selection of
correct algorithm of treatment for each patient.


.
,
.

,

(, , ).

,


(, , ).

(
, , ,
, ).
, ,
.
.

,
, - ,
, """"
*1+.
:
.

,
.

, ,
,
.

, ,
.

.

*3, 4+.
- (, ,
, , , .),

- , ,
. """" ,
""

144 | III
"",
.

.
,
"""",
, ( )
, ,
. ,

.

, ,
, , , ,
.
,
, -

, , ,
( ),
(, ,
, .) *2+.


. 4 :
,
,

,
.
,
, ,
.
,
.

*4,5+.
,

.
eee eoooo c oo Cce DR9000,
DR9500 - ao o eo ee *3+.
DRX9000 ,

.
, ,
,
, . DRX9000
,
. ,

, ,
. .

,
""""

. .
.
,
.
,
,
,

, ,

. ,

*6,7+.
, ,
.

, ,

.

.

.
.
.. , ..
[email protected]
,
,
: .. ..
LAPAROSKOPICHESKY APPENDICITIS. EFFICIENCY OF THE METHOD.
Sadovnikova E.U. , Borisov Y.A.
Peoples' Friendship University of Russia, Russia, Moscow
The Faculty of Medicine ,Department of faculty surgery
Scientific Adviser:Ph.D.Lebedev N.V.
Keywords: Appendicitis, laparoscopy
: , ,
,


( 7 % ). ,
1231% ,
. 16,735%

.
( 45%)
-
.
5
:
.
-
.

( 5,2% ),
. ,
,
, 42,9%
.
24
.

(-, .)
.
, 40%
(2/3
).

.
, ,
2

. ,

,*1-2+
.

.*3-4]

.
, ,
, , . .
(
) ,
.* 5 + ,
11,7%
.*
6]
,
,
. ( . .
),
,
2831% 5,58%.

 . , , , 2011 | 145

, . . .

,
.*7-8+

: ,
,
,

, ,
,
( ,
, .).
,

:*9-10+

( IIIII ,
);
; ,
.
: ,
, , , .

.
.
:



,

:
1.

. 2.


.
10% . 3.


. 4.

. 5.

.
:
1. .., .., ..
. 1990; 3: 118122.
2. ..
. 1997; 5: 84-87. 3.
.. :
. . ... - . . 1966.
3.

..
-

. :
1965.
4. ..

. 1998; 3: 62.
5. .., .. -
. 1981; 4: 24-26.
6. .., .., .. .
.
. 1991; 9: 119-123.
7. .., .., .. .
. 1994; 4: 18-20.

8. .., .., ..
.
1996.
9. Kazemier G., de Zeeuw G.R., Bonjer H.J. et al.
:
: 4-
(). 1996;
32.
10. Kingler A., Henle K.P., Beller S. et al. Laparoscopic appendectomy
does not change the incidence of postoperative infection complications.
Am J Surg 1998; 175: 3: 232-235.

.., .., ..
[email protected]
, ,
,
: , ...,
..
EVALUATION OF THE FUNCTIONAL STATE OF THE PANCREAS AFTER
COMBINED TREATMENT AND (EVALUATION ) RADIATION
PATHOMORPHISM AFTER RADICAL RADIOTHERAPY OF
PANCREATOBILIARY CANCER
Tazin V.N., Asmaryan A.G., Eltishev N.A.
Peoples' Friendship University of Russia, Russia, Moscow
The Faculty of Medicine, Department of Oncology and Radiology
Scientific Adviser: Ph. D. Harchenko V.P.
Keywords: pancreatobiliary cancer, pankreatoenteroanastomosis
: ,

Abstract: Have been evaluated the functions of the stump of the

pancreas after combined treatment, the development of techniques to
prevent violations of exo- and endocrine functions of the stump of the
pancreas.
Developed
a
new
method
of
forming
pankreatoenteroanastomosis hindering the development of digestive
disorders, severe diabetes mellitus.Radiotherapy method of ""shrinking
field"" has allowed 95% of patients stated no change in the profile
secretes hormones and enzymes stump of the pancreas.

10-12%
.
,

.

10% ,

.
,
.
,

,
.

,
,

,
,

.

146 | III
,
-
,
,
.

,

.
1989 2009 . 72
: 60 -
, 6
6
.

,

.
-
,
,

.

.

95%

.
,

.

,

78% 12-16
III ,
.

.
2004-2008 .
..
[email protected]
, ,
,
: ... ..
THE ANALYSIS OF DIAGNOSTICS AND TREATMENT OF POSTNECROTIC
CYSTS OF A PANCREAS FOR 2004-2008
Tishkov A.S.
Kursk State Medical University, Russia, Kursk
Medical faculty, Department of the general surgery
Scientific Adviser: Ph.D.Sukovatyh B.S.
Keywords: Postnecrotic cyst, sterile, infected, a laparotomy, a
destructive pancreatitis
: , ,
, -, , ,

Abstract: Now the sharp pancreatitis takes the third place among
emergency pathologies. High growth of patients with the given
pathology is annually marked, and also the quantity of patients with
destructive forms of a sharp pancreatitis increases. One of the most
frequent complications of a destructive pancreatitis are postnecrotic
pseudo-cysts of a pancreas. In the course of formation of postnecrotic
pseudo-cysts of a pancreas often there are such terrible complications
as punching, the bleeding, a suppuration, a mechanical jaundice,
impassability of the gastroenteric path, which frequency fluctuates
within 20-50 %, the lethality thus can reach 40-60 %.

.
70
,
. 2004 2008 .
5
54 - 2004 , 82
2008 . 22 - 36%
.

13 23%
.

57(82%) , 9(13%)
- , 3(4%)
1(1%)
. 24
14(20%) , 24
56(80%) . 19 81 .
- 60
(86%), 10 (14%), 63 (90%)
. 36 (51%)
, 34 (49%) . 57
(81%) , (2 ) 13 (19%) .

32 (45%) , 13 (19%), 12 (17%),
13 (19%) .
3 20 ,
24(34%) 3-6 ,
(34%) 6-8 , 9(13%) 8-10 ,
13(19%) 10 .
62 (89%)
. 8 (11%)
. ,

.

,
.
45 (73%), 15 (24%)
2 (3%) .
38 ,
5 , 2 .
9
, 6 .
.
:
10 (29%) , 9 (26%), -
8 (24%) , .coli 7 (21%)
.
70 (100%) . 67 (95,7%)
,
. 1 (1,4%)
, ,

,
. 2 (2,9%)
,

, .

8 (11%) ,
5

-. C
14 (20%) ,
4 10

 . , , , 2011 | 147
.

.
6
(9%) , 5
.
3 (4%)
.

16,56 9,04
, 37,06 19,17
.
4,3%.

-

.., .., ..
[email protected]
, ,
,
: ... . ..
ULTRASOUND MONITORING IN PATIENTS WITH OBSTRUCTIVE
COLONIC OBSTRUCTION
Toltoev M.M., Kirshin A.P., Valeev A.A.
Kazan State Medical Academy, Russia, Kazan
The Faculty of Surgery, Department of Surgery
Scientific Adviser: Ph. D. Malkov I.S.
KeywordsL Ultrasound, obturatsionnnaya colonic obstruction, colon
cancer, diagnosis
: ,
, ,
Abstract: Analyzed the results of pre-and postoperative study of 28
patients diagnosed with obstructive colon obstruction. Ultrasound
examination noted the presence of obstruction of 92.8% of cases. But to
set the level of obstruction was only 17.8% of patients. The wall
thickness hyperinflate loops of colon averaged 10.9 mm. Bowel wall
thickness is largely dependent on the duration of the pathological
process than on the level of obstruction, colon obstruction. In 17
patients (60.7%) wore a pendular peristalsis or recurrent - ongoing.

()

.

.

(), ,
,
.


.

28
.

. 16 (57,1%) 12
(42,9%), 54-89 ,
64,9 .
24 11
(39,3%), 17 (60,7%)

. 24
(85,7%), 2, 2
.
,

( ,

, ), ,
.
.
: 1)
2) 3)
4) ,
, 5) 6)
.


92,8% .
17,8% .
,
,
,
.


. ,

17,8%.


.
,
, 7,8 13,2 (
10,9).

. , 11 ,
24
, (
9,1 ), 17 ,
24 ( 11,7 ). ,

,

.

, 17 (60,7%)

.

.

.

78,6% . ,

.
. ,

92,8%.
, ,

.
, ,
, ,
.

-
.
.., ..
[email protected]
, ,
,
: ... .., ... ..
SURGICAL SERVICE OF DEGENERATIVE DISC DISEASES
LUMBOSACRAL SPINE BY VENTRAL TECHNIC.
Shevchenko A.A., Son A.I.
Peoples' Friendship University of Russia, Russia, Moscow

IN

148 | III
The Faculty of Medicine, Department of traumatology and orthopedics
Scientific Adviser: M.D. Zagorodny N.V., M.D. Dotsenko V.V.
Keywords: degenerative diseases of the spine, lumbosacral spine,
ventral method, vertebrology.
: ,
- , ,
.
Abstract: Continue debate about efficiency and relevance of the surgical
service of degenerative disc diseases in lumbosacral spine by ventral
technic. For the purpose of stabilization of the functional spinal unit
were used ring-shaped titanium implants (300 surgical interventions)
and combined corporodesis by autogenous bone (60).
Pain syndrome disappeared straight after the surgical intervention in
304 cases. As a matter of record we have concluded that previously
mentioned technic enables to eradicate the pathologic focus and
stabilize disease segment.

.
.


- ,
, ,
.
,
,

.

,
. .
,

.
.

.
,

.
.


. ,
.
.

360 , 2008 2010
. -
. 18 78
.

-. -

(300 ),
(60).
.

1 3 . 3, 6, 12
. :
,
.

.
304.
.
.

.
.
:
1. .
2. .
3. .
4. -
.
5.
.
6. .
7.
.

-
.
.., ..
[email protected]
, ,
,
: ... .., ... ..
HOISE OF THE SURGICAL TREATMENT OF DEGENERATIVE STENOSIS
OF THE LUMBOSACRAL SPINE IN ELDERLY.
Shevchenko A.A., Son A.I.
Peoples' Friendship University of Russia, Russia, Moscow
The Faculty of Medicine, Department of traumatology and orthopaedics
M.D. Zagorodny N.V., M.D. Dotsenko V.V.
Keywords: Surgical treatment of spinal stenosis, stenosis of the
lumbosacral, vertebrology.
: ,
- , .
Abstract: The
treatment of the degenerative stenosis of the
lumbosacral spine in elderly involves a certain difficulty. There were
enquired 47 patients: 17 had radical surgery, 23 were operated without
active influence on supporting formations of the vertebral column, 7 had
surgical interventions without anchoring by hardwares.
By virtue of above-described we came to the conclusion that we have an
opportunity to define strength and functionality of the hardware by
measuring of bone content density.

,

.
,
. , 95 %

, 50%
.

,

: (
) ,
, . ,

, .
: 47
,
2008-2010
.
: 60 ,
-
- . 30 17 .

,
-
.

 . , , , 2011 | 149

, .
: 17
, , ..
,

,

().


( ),
, 7
,
( ).
23 ,

- :
DIAM
,

.

,
. 7
,
, .
:
-

.
, ,
,

, , ,
, .

.., ..
[email protected]
, ,
,
: ... ..
USING NEW GENERATION DYNAMIC INTERSPINOUS IMPLANT IN THE
TREATMENT OF DEGENERATIVE LUMBAR SPINE
Shevchenko A.A., Son A.I.
Peoples' Friendship University of Russia, Moscow, Russia
The Faculty of Medicine, Department of Traumatology and Orthopedics
Scientific Adviser: Ph.D. ABDULHABIROV M.A.
Keywords: interspinous dynamic fixation, degenerative
spine diseases, surgical treatment
: ,
,
Abstract: Was produced the outcome analysis of international
investigations and short-term results assessment of the surgical
treatment of degenerative lumbar spine damages with using the
dynamic interspinous implant COFLEX. Dynamic interspinous anchorage
was used in 154 cases. In 141 cases was attained positive result. The
treatment with the application of Coflex for the purpose of lumbar
spine dynamic stabilization after the nervous structure decompression
allows reduce the lumbalgia without spondylosyndesis.


,

,
.
,

.

Coflex.

(Ostseeklinik Damp, Department of Neurosurgery, Damp, Germany).
. (., ..
),

Coflex.
.
154
. 64 (42 %) 90 (58
%) ; 66 (43 %) 40 65
88 (57 %) 65 . 96 (62 %) ,
42 (27 %) , 16 (11 %)
. 14,5 .
. 92 (60 %) 154
.
55 (60 %) , 37 (40 %)
. 137 (89 %)
1000 , 134 (87 %)
1000 . , 141 (92 %)
, 13
(8 %) .
5 (3 %)
: ,
, .
,
; ( 5
)
.
. 12
,
,
.


. 72 %
. ,
- ,
.
92 %.
.
,
-

.

:
.
.., ..
[email protected]
, ,
,
: ... ..
MINIMALLY INVASIVE PERCUTANEOUS HYDRODISCECTOMY:
PRELIMINARY REPORT OF FOREIGN STUDIES.
Shevchenko A.A., Son A.I.
Peoples' Friendship University of Russia, Russia, Moscow
The Faculty of Medicine, Department of traumatology and orthopedics
Scientific adviser: Ph.D. ABDULHABIROV M.A.
Keywords: minimally invasive technique, hydrodiscectomy,
percutaneous, degenerative disc
: , ,
,

150 | III
Abstract: In this article its reported the feasibility of percutaneous
hydrodiscectomy. A total of 13 patients who underwent
hydrodiscectomy were evaluated. Using Odoms criteria there were 12
patients (92,3%) with excellent and good results and one patient with a
poor result (7,7%).
Conclusion: Percutaneous hydrodiscectomy could be a good alternative
procedure in surgical treatment of lumbar disc degenerative disease.

.
,
.
,
.
.

,

. , ,

, ,
.

,
, .

,
(HJ Han, MD; WK Kim, MD; CK Park,
MD; SH Oh, MD; DG Lee, MD; ES Doh, MD).
. 2007 2008 .

13 (Department of Neurosurgery, Gachon
University Gil Medical Center, Incheon, Corea).
:
( 12 ) ( 1 ).
.


.
. 13 10 3 .
38 .
18,7 18,3 4,7 1,98
. 5,5 1,3 .

6,2 1,9 8,5 1,1 .

3 1,4 (<0,05) 2,7 1,0 (<0,05)
.
48 19.1%,
23 22,1% (<0,05). Odom 5
(38,5%) , 7 (53,8%)
, (7,7%) .
. ,


,
.
92%
.

.

,
.., .., ..


:
() (): . . .
SURGICAL AND RADIATION TREATMANT OF PANCREATOBILIARY
CANCER COMPLICATED BY JAUNDICE
Asmaryan H.G., Tazin V.N., Eltishev N.A.
Peoples Friendship University of Russia

The Faculty of Medicine

Department: Oncology and Raoentgenoradiology
Scientific Adviser(s): Prof. Kharchenko N.V.
Keywords: pancreatobiliary cancer, jaundice, palliative surgical
treatment, radiation therapy
: , ,
, .
Abstract: Have been analyzed the histories of cases of 261 patients with
pancreatobiliary cancer, which got treatment in Russian Research Center
of Roentgenoradiology since 1988 till 2010. 72 patients have received
combined (at first stage- radical surgical, on second stage- radiation
treatment), 135 radiation and 54 palliative surgical treatment. The
effectiveness of the combined treatment and of radiation therapy (in
cases of contraindications to surgery) for the pancreatobiliary cancer is
demonstrated.

,
,

.
8-15% ,

15 %, 5- 7,8-15,8%,

4,2-6,3 .
,

, ,

.
261
,
1988 2010 . 93
, 110 - , 58
- . 213

, 4 -
. 44


.
213
, ,
(23 )

(190 ).
72, - 135 ,
- 54 .

.
4 , 13 ; 16 , 12 -
. 27
.

.

.
,
.
.
1,8-2 .;
50-60 . ; 66-70 .
66-80 . .
72
, 129 - , 44 -
.
3-5-

47,3%+12,1, 22,5%+10,3;

 . , , , 2011 | 151
41,0%+12,6, 22,0%+10,3; 63,3%+9,1,
28,1%+8,5.
, 3-5-

22,7+3,1 ., 10,6%+4,5, 2,1%+2,1;
- 19,9+3,9 ., 9,3%+3,9, 1,8%+1,8;
- 30,8+4,3 ., 15,0%+7,9, 5,0%+4,8.


9,2+0,8 ., 7,7+0,6 ., - 11,4+1,3 .

.

,

.

[
.
,
.]

[]
[PSYCHIATRY]

 . , , , 2011 | 153
HELPING THE HELPERS - MENTAL AND SOMATIC HEALTH OF CHILD
WELFARE PROFESSIONALS WITH PARTICULAR REGARD TO THE SIGNS
OF BURNOUT
Institute of Behavioural Sciences, Semmelweis University
Gyula Marton Kohl
[email protected]
Scientific Adviser(s): Prof. Ferenc Try MD, PhD
Introduction. It is well-known based on the international and inland
researches that human services workers are increasingly at risk for
burnout syndrome; also their somatic and mental health indicators show
lower values than those in similar socio-economic situation. In
developing countries, including Hungary and Russia, child protection is
one of the most overladen social welfare services, due to the increasing
responsibilities caused by the social transformation and due to the lack
of human resources and financies. However, in contrast to the
frequently tested healthcare staff, people working in this field seem to
be overlooked in the scientific literature.
Aims. Under the topic Supporting policies facing the child welfare
professionals working in the capital helping the helpers of the
Budapest Scholarship Program we assessed the mental and somatic
health of child welfare professionals with particular regard to the signs
of burnout.
Methods. To measure the mental and somatic health indicators, as well
as the signs of burnout, anonymous screening was performed using
validated questionnaires among 594 orphanage workers and 286 foster
parents. The number of respondents was 131 and 34 (response rate:
18.75%). The results were compared with the 2002 Hungarostudy
representative household survey (N = 1754), with a representative
physician (N=407) and with a psychiatrist (N=220) control group.
Results. 42.4% of the child protection workers regularly faces workrelated stressful, tense situations, and in this context 33.9% of them
feels constantly overwhelmed. Measured by the Maslach Burnout
Inventory, 5.6% of the men shows moderate, 8.3% high degree of
emotional exhaustion, among women 15.9% and 13.1%.
Depersonalization is moderate in 8.8%, high in 2.8% of the men, in 7.8%
and in 6.9% of the women. The Beck Depression Inventory shows mild
symptoms of depression in 2.6% of the men and in 5.0% of the women.
There are no significant differences between the genders. Among those
who can be characterized with a high degree of emotional exhaustion or
with the symptoms of mild depression significantly higher scores has
been achieved on the escape-avoidance scale of the Lazarus Ways of
Coping
Questionnare
(for
emotional
exhaustion:
ANOVA:
f(2,175)=5,161, p=0,007, Tukeys b: p<0,05; for mild depression: twosample t-test: d(6,206)=-2,628; p=0,038). 25.5% of the respondents felt
deterioration in health status in the last 5 years, 29.1% hold it now only
moderate, bad or very bad. Indeed, we found that the prevalence of
chronic somatic morbidity among both female and male child welfare
workers is higher than that in the Hungarostudy and physician control
groups. Furthermore, physical acticity is the lowest compared with all of
the respective control groups, while smoking and alcohol consumption
seems to be more severe than the national average.
Conclusions. The rate of burnout symptoms is quite high, and this
applies to both genders. The rate of depressive symptoms also deserves
attention, although it does not exceed the frequency observed in the
general population. While confirming the international literature, our
data identify a new high-risk group, and repeatedly draw attention to
the importance of screening and prevention of burnout phenomena, as
well as to the challenges of organizing the care for vulnerable persons.

.., .., .., ..

() (): ..., ..
CORRELATION BETWEEN CLINICAL FORMS OF SCHIZOPHRENIA IN
FAMILY
Pisaryuk A.., Chernobulskay N., Shitikova A., Birukova M.
Department of psychiatry and medical psychology PFUR, Moscow.
Scientific Adviser(s): professor Artemieva M.
Key words: inheritance of schizophrenia, clinical forms of split mind,
family illness

Abstract: The main object of this work is to find the connection between
clinically significant of schizophrenia in family. Fords theory had been
taken in base of this work. In fact we can suppose: if the mother who
suffer catatonic split mind have a sick child, his clinically significant is
going to the same way. We used the next methods: questioning, sc.
PANSS, database formation and statistical processing of database, with
program Statistic 6.0. The result of research can help with forecast of
disease and genetic counseling.


.
(1960).
, ,

.
.

, , , ,
, ,

, ,
80 - 100%,

.

.
:
.
: ,
PANSS,


6,0.
: 10 2

:

.
,
,
, .

.

,

,
.
: 10
: 2
; 5 ,
3
; 3 ,
- .
:
.
,
, ,

, .

, ,

,
, .

. .

154 | III
[email protected]
. . .
, , .
,

() (): .., . . .
SUBJECTIVE PSYCHOLOGY OF TRUE HALLUCINATIONS AND
PSEUDOHALLUCINATIONS
Voinova N. A.
Russian State Medical University named by N. I. Pirogov, Russia, Moscow
Medical faculty, the chair of psychiatry and medical psychology
Scientific Adviser(s): associate professor B. A. Voskresensky
Keywords: true hallucinations, pseudohallucinations, normal psychical
functions
: , ,

Abstract: True hallucinations and pseudo hallucinations are known as
typical for some psychiatric disorders. Their correlation with normal
psychical functions such as perception and conception has been
discussed for a long time. The aim of present research was to investigate
this possibility studying the patients' subjective psychic organization by
taking their subjective interpretation of the ""perception"",
""conception"" and, after, their own correlation of their hallucinatory
disorder with one of these terms. The results have shown the
fundamental difference between perception as normal psychical
function and perception as morbid, forcible experience.

.
(
.) .
, ,
( )
.

.
25
(F20, F23)
( 1). 5
.
(F3),
- (4
2). 3 , 15 .
- .
-; ,


( ). :

,
( ,
). ,
.
. 3
,
.
2 . :
,
, ,

, .
,
(
)
.

.
..
[email protected]

. ..
,

() (): ... ..
RISK FACTORS FOR SUICIDE ON THE DIFFERENT STADIUMS OF
ALCOHOLISM.
Guzilova J.I.
First Moscow Medical State University of I.M.Sechenov
Medical Faculty
Scientific Adviser(s): Ph. D. Ursova L.G.
Keywords: psychiatry, alcoholism, suicide, risk factors
: , , , ,

Abstract: The aim of this research was to estimate the risk factors of
suicide in the patients with alcohol abuse. 33% of the patients had
suicide-activity in the past. The main risk factors for men with physical
dependence were social pessimism (55%), affectivity (43%) and
maximalism (38,9%). The main risk factors for women with physical
dependence were self-criticism (56,7%), affectivity (56,1%) and social
pessimism and maximalism (50%). The main risk factors on the last
stadium of alcohol abuse are social pessimism, self-criticism and
affectivity. The risk of suicide is higher for women, and on the last
stadium of alcoholism.
:
7%. 7-15%
.
20-60
, .


.
: 33
(26 7 ) 25-67
( 43,511,5)
15,29,1 . 24 (73%)
, 9 (27%) .
17 (52%) (13 4 ), 18
(55%) (13 5 ), 3
(9%) ,12 (36%)

. 2
, 3- . 4
-, 2
, 4 - , 1 .
:
HADS,
.
SPSS
v. 10.5.
DS 14 ,
.
: 8 /, 8-10
/,
; 11
/, .
29 .
, ,
, , ,
, , ,
; .
,
.
: 26 (79%);
6 (18%), 1 (3%).
21 (64%), 9
(27%), 3 (9%).
33% , 6%
, 27%

 . , , , 2011 | 155
, 15%
, 9% .

(55%), (43,5%),
(38,9%).
:
(57%), - (55%)
(54%).
(81% 50%)
.

(56,7%), (56,1%),
( 50%).

75%.
:
1.

.
2.
(33%)
,
.
3.
:
, , .
4.

, ,
.
5.

,
.
6.

: ,
- , .
7.


, , .
8.

(75%) 3 (81%)

.

..
[email protected]
. . ..
, ,
,
() (): ..., ..
PSYCHOAUTONOMIC STATUS IN PATIENTS WITH IDIOPATHIC
MUSCULAR DYSTONIA
MAKAROV E.V.
Perm State Academy of Medicine named after Academician E.Wagner,
Russia, Perm
Medical Faculty, Department of neurology
Scientific Adviser(s): MDDr., professor Karakulova Yu.V.
Keywords: muscular dystonia, hyperkinesis, psychoautonomic
disturbances, personal anxiety
: , ,
,
Abstract: uscular dystonia is chronic disease of extrapyramidal system
associated with neurotransmitters disturbances. It is known, patients
with muscular dystonia have emotional disorders. The complex
psychometric study of 18 patients with muscular dystonia was
performed. It included 11 females and 7 males (the average age
48,5616,97). The patients were divided into 2 groups: 10 patients had
focal dystonia, 8 patients suffered from a segment and generalized
dystonia. Emotional status study showed the increase of personal
anxiety and HADS scale anxiety, which correlated with a duration of
hyperkinesis and intensity of dystonia.

,

,
.
,
.

,
, , - ,
, . ,
-
.
:

.
: 18 .
11 7 . 48,5616,97 . 2 : 10

,
8

.
4 , 5
1 .
8,097,55 . 11
, 7 .
15 , - .
7 , 5
.
8 , 6.


.
.
(HADS),
-
,
.
IBM PC
Statistica v.6
0,05.
.
:
14,4410,57.
(3,193,71 ).
1,692,41 1,632,96
.
15,06,3 ,
(<0,025) , (9,472,47).

18,757,51 , (<0,005) ,
(10,271,75). HADS
7,134,03 ,
(<0,05) , (3,071,79 ).
HADS 9,334,89
, (<0,1) ,
(4,42,64). (51,4213,55 )
(54,1812,19 ) -
(<0,005) ,
(32,533,23 36,073,86 ).

40,7218,69 ,
(<0,01) , (32,82,86).

(>0,05).
HADS

.
:
.
, HADS,
.

156 | III

(,
, )
..
[email protected]
, ,
, ,

() (): .., ..,
.., ..
[email protected]
EFFECTIVENESS OF THE COPING STRATEGIES USED BY PATIENTS WITH
CHRONIC DISEASES (SCHIZOPHRENIA, ESSENTIAL HYPERTENSION,
PSORIASIS)
Getman X.V.
Peoples' Friendship University of Russia, Russia, Moscow
The faculty of medicine, department of public health, healthcare
organization and social hygiene
Scientific Adviser(s): Radzinskaya E.V., Zavalishina A.I., Yeryomichev R.Y.,
Ostretsova M.A.
Keywords: coping strategies, chronic diseases, schizophrenia, psoriasis,
essential hypertension
: , ,
, ,
Abstract: Studying coping strategies in patients with chronic diseases is a
particularly poignant due to the absence of a tendency for chronic
diseases to decrease in number. Schizophrenics use social support search
and distancing more often than healthy people. The quality of life for
schizophrenics is in direct correlation with the problem solution planning
and positive revaluation, but it decreases if they use avoidance and
acceptance of responsibility. The quality of life for patients with psoriasis
depends directly on the confrontation and is inversely related with
distancing and avoidance.
-,
XXI ,
, .
,
, ,
, ,
(., 1949). ,
,
,
. , .
-

.
, ,
, .

() (
)
2010-2011 . ( ., 1988;

.. ., 2005)

35
.
135 (30 , ; 15
).

(92
127 ).

, ,
,
.
,

(63,3%; <0,05), (61,1%)
(

61,1%, 52,8%).
(52,7%
44,4% ).

- (r=
-0,45 ).
, , ,
.


.
- ,
,
, (r = -0,42).
,
.

,
- (r =
-0,58).

.

.
(Frydenberg,
2002),
, , ..

.




.

(, , )
..
[email protected]
..
, ,
,

() (): ..., . ..
OMPUTER ADDICTION IN PATIENTS WITH MENTAL DISORDERS (
LINIC, DYNAMICS, COMORBIDITY) Shcherbatyuk a.v.
N.I. Pirogov Russian State Medical University, Russia, Moscow
Moscow Faculty, Department of Psychiatry and Medical Psychology
Scientific Adviser(s): PhD, Assoc. Prof. V.B. Minikaev
Keywords: omputer addiction, mental illness, dynamics, comorbidity,
computer preferences, emotional and behavioral reaction, the ""virtual
world""
: ,
,, ,
, ,
"" ""
Abstract: To investigate the clinical characteristics, the dynamics of
mental illness and computer addiction, examined 19 patients who were
treated in a psychiatric hospital - the main group and 11 healthy
individuals - control group. Revealed that the computer preferences are
manifested in the structure of mental disorders, and behavioral and
emotional reactions emerging in virtual interaction, determine the
pattern of behavior in patients with mental disorders. Computer
addiction is formed in the premorbid tends to pathomorphism.

, ,
,

.
30

, : 19 ,

 . , , , 2011 | 157
1 . ..
, 11
.

.
(
19 36 )
;
, ,
;

,
.
( 18 36
) -
;
; ,
,
;

.
:
1.

2.



.
3. ,
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)

) ,
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,
, .

,


.
.., ..
[email protected]
, ,
,

() (): .., ..
DIFFERENCIAL APPROACH TO PRESCRIPTION OF SYCHOTROPIC
PREPARATIONS FOR PATIENTS SUFFERING FROM PAROXYSMAL FORM
OF ATRIUMS FIBRILLATION ACCOUNTING PSYCHOLOGICAL
PERSONALITY CHARACTERISTICS INFLUENCE ON NOSOGENETIC
DEPRESSION EXPRESSION.
Yourovskaya I.I, M.S Artemieva
Peoples Friendship University of Russia, Russia, Moscow
The Faculty of Medicine, Department of psychiatry and medical
psychology
Scientific Adviser(s): M.S Artemieva
Keywords: nosogenetic depression, paroxysmal form of atrium
fibrillation, psychological personality characteristics, alarm,
pedantical, hypertymic, harmonical personality accentuation
shape, radiofrequent ablation operation, paroxetin.
: ,
, ,
, , ,
, , .

Abstract: This research work is dedicated to examination of psychological

personality characteristics influence on development of depression and
depression expression by patiens suffering from paroxysmal form of
atriums fibrillation. There were inspected 43 heart station patients. The
result of it was: the patients liable to hypertymic shape of
personality accentuation did not discover any symptoms of depression.
The patients liable to alarm shape of personality accentuation are
exposed to the most severe form of nosogenetic depression. It intails
acceleration and expansion of atriums fibrillation spells. The patients
liable to pedantical shape of personality accentuation suffer rarely
from depression. The illness has a mild form in that case.
:
,
;

.
: 43
(25
(58%), 56,5 18 (42%),
50.4 ).
- -
.

.



:
- 12 (27.9%) 18 (41.9%);
4 (9.3%) 2
(4.7%);
4 (9.3%);
- 2 (4.7% ) 1 (
2.3%).
4


,
:
I (4 -9.3%)
( 2 6),
.
II (7 -16.3%)
( 9 2.5). 4
(57.1%) , 1 (14.3%) 2 (28.6 %)
.
III (32 - 74.4%)
( 211.5). 28 (87.5%)
, 3 (9.4%) 1(3.1%)
.

20-40 / 21
.
.
3-5
,
,
;
-83.5,
.
10 ( 23.2%)
- .




,

,
.



.
,


,

158 | III

,
,

, .
,

,

.
:
1.
.., .. .-.
2005.- 778.
2.

..

, ,
.-. -. 2009.-238
3.
. .
.., . ..-. -.
2010.-408 .
4.
. .-.. 2002.-358
5.
.., .., ..

- (
)// .-2005.- 6.-.26-31.
6.
.., .., ..

.//. .-2001.-9.-.55-61.

-
.
.., ..
[email protected]

, ,
"
() (): ... ..
SOCIAL - PSYCHOLOGICAL ITEMS OF DISADAPTATION BEHAVIOR OF
TEENAGERS
Yakovenko M.P., Yakovenko M.P.
Kuban State Medical University
General Medicine
Department of public health and public health services
Scientific Adviser(s): Ph.D. Gurbich G.I.
Keywords: teenagers, hobbies, a previous conviction, alcohol, drugs,
disadaptation behavior
: , , , ,
,
Abstract: We interrogated 180 teenagers at the age of 14-18 years by
means of the original questionnaire. Children have been divided into 2
groups. Compared frequency of alcohol intake, drugs, smoking, a
previous conviction at parents. The risk disadaptation was estimated.
Earlier revealed factors of disadaptation behavior in the teenage
environment, harmonization of intrafamily relations promotes
preventive maintenance disadaptation. Problems social disadaptation
are characteristic not only for the teenagers who are in socially
unsuccessful position, but also for safe teenagers.
, ,
, .. ,
, , ,
, ,
...
,
,
.
-
,

. 180 14-18 .
. 2 . I 60 ,
,
. 24
36 . II - 120
,
72 48.
, ,
2 I ,
( 7,3
). II
( , , ,
, ), I
. ,
12 .
,
I .
2,5 ,
. I 7,2
II, , I
, II .
I ,
II .
,
,
.
,
,
.

, ,
,
,

:
.
..
[email protected]
, ,
,
() (): ... ..
SMOKING AMONG TEENAGERS: THE REASONS OF FORMATION AND
BAD HABIT DISTRIBUTION.
Gluhova D.P.
Peoples' Friendship University of Russia, Russia, Moscow
The Faculty of Medicine, Department of Biochemistry
Scientific Adviser(s): PhD Kuznietsova O.M.
Keywords: smoking , nicotinic dependence, bad habit, influence,
prevalence, vocational guidance
: , ,
, , ,

Abstract: Research of prevalence of smoking among teenagers with use

of anonymous questioning.

.
, ,
. ,
.
:

.
: ,
;
;
; ;

 . , , , 2011 | 159
; ,
.
: 10-11 ,
70 ( 15-18
).
:
70 15 (21 %),
- 8 (53%), 7 (47%).
, :
1) 13-14
(90% );
2) 47%
;
3) -
;
4) 46% , ,
5) 60 %
;
6) 40 %
7) 4 ( 27%),
6
(40 %), 5 (33 %).
8) ,
30%.
:
13-14
.

,
,
,
.

,

,

.
,
.

,

.

, ,
.

.

,

.
.., ..
[email protected]
, ,

() (): ... ..
BORDER DISORDER, EMANATING FROM THE FUTURE DOCTORS WITHIN
EMERGING BURNOUT INITIAL STAGES OF ADAPTING TO THE
PROFESSION.
Zalilova Z.K., Pankova O.F.
Russian State Medical University,
Russia, Moscow
Chair of psychiatry and medical psychology
Scientific Adviser(s): Ph.D. Pancova O.F.
Keywords: burnout, reasons, psycho-correction, violation of
adaptation,neurosis,conflict, coping-strategies
: c , ,
, , , ,
-

Abstract: The urgency of the problem is the high incidence of eating

disorders spectrum for future physicians edge and young professionals
due to professional formation at the initial stages of adapting to the
occupation and the lack of adequate psychological assistance. The
purpose of this study is to identify personal characteristics of young
professionals, emerging behavioural disorders, neurotic and external
social and situational factors contributing to the emotional and
professional deformation, fading to developing methods of prevention
and of psychocorrection.

.

,
,

...

-
FPI,
-,
, (SACS).
320 2,5 6
.
4
39 .


,

,
. ( 75%
86%),
,
,
.
, ,
( 50%
2. 85% 5.),
. ,

(
90%) ( 60%
90%).
.
.

,
.
:


,
.

,
,
, .
,

, .. , .

,

,
.

.

160 | III
-
.
..
[email protected]
, ,

() (): ... ..
ALTERNATIVE METHOD OF TREATMENT OF STRESS-HYPERTENSION IN
STUDENTS.
Kovalchuk O.D.
Kuban State Medical University, Russia, Krasnodar
Medical Faculty, Department of general and clinical pathophysiology
Scientific Adviser(s): Doctor of Medicine Kade A.Kh.
Keywords: stress-hypertension, TES-therapy, stress, stress resistance
: - ,
, , .
Abstract: The study of TES-therapy effects on students with stresshypertension showed the stimulation of the brain endogenic opioid
structures results in blood pressure normalization, stress resistance
increase, stress level decrease, sleep
and cognitive functions
improvement, depressive and vegetative disorders decrease and general
condition improvement.
:

-
().
, -
,
.
: -,
-
.
.
64
(2025 ) - .
,
.
2 : 1, ,
- 2, ,
, .
, ,
, .
(
,
, ,
. ),
,
.


.
1 10 -.
(, ,
), 5 10
.
.
. 1
,
3-4 .
, 42%
. 1
, ,
67% , ,
2
. 75% 1
,
.
1 . ,

,
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1 ,
,

.

1,

, ,
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83%
1.
92% 1. 2
.
. ,
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- ,
, ,
, ,
, ,
,
- -
.

..
.
, .
() (): ... ..
INDICATOR RELATIONSHIP OF PERSONAL AND REACTIVE ANXIETY IN
STUDENTS DURING THEIR STUDY PROCESS.
Zuurbekova D.P.
Tajik State Medical University named after Abuali ibni Sino, Dushanbe
Scientific Adviser(s): PhD, Halimova F.T.
Keywords: personal and reactive anxiety, adaptation, motivation and
emotional tension
: , ,
,
Summary: the study involved 480 students who have studied the levels
of personal (PA) and reactive (RA) anxiety. There have been allocated 4
types according to the ratio of PA and RA, which determine the degree
of motivation for successful activity, the tendency to a nervous
breakdown and resistance of students to emotional stress.

(.., 2005, 2006)
,

,
,
(.., 1994, 1997).
.

, , ,
.

,
,
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,

. 480
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: 1)

 . , , , 2011 | 161
; 2)

; 3)
.
. .
4
:
1 , ,

;
2 ,
;
3 ,

;
4 , ,

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(53%)
. (16%) ,
,

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4-5- (23%)
,
,
.

,
.
,
.

,
, ,
, .
,
,
, .

, ,
.

.

.
() (): ..., ..)
STUDENTS MOTIVATIONAL ASSESSMENT
Said Khalil Said Jabbar
Tajik State Medical University named after Abuali ibni Sino
Scientific Adviser(s): MD, professor Shukurov F.A.)
Keywords: motivation, personality and anxiety, emotional stress.
: , ,

Abstract: the study involved 480 students who have studied the level of
personal (PA) and reactive (RA) anxiety. Established levels of PA and RA
indicate the propensity of students to neurotic breakdowns on the one
hand and an adequate adaptation.

.

,
,
.
.

-
.
,
.
. ,
, ,

.
.


, .
480 ,
() () .
, .

()
, (46,8%)
-
.
41,6% ,

.
3,5%

0,8% 7,1%.

(46,9%) .
,
. , 58,2%

. 38,9%

,

. (2,9%)
,
.

, (52,8%)
,
.
.
(6,3%)
, .
(2,9%) .
.

(43,1%) ,
,
. ,
8,6 % ,
12-
.

()

C.
.
, .
() (): ..., ..
CORRELATION OF MIZODZHA (IN KIND) WITH THE TYPES OF HIGHER
NERVOUS ACTIVITY AND TEMPERAMENTS.
Karimzod S.
Tajik State Medical University named after Abuali ibni Sino, Dushanbe
Scientific Adviser(s): MD, professor Shukurov F.A.
Keywords: "mizodzh" (nature), temperament, types of HNA
: (), ,
Summary: in this article, a comparative analysis of the categories used
by Avicenna to determine nature and properties of neural processes in
the cerebral cortex of Pavlov I.P. As a result of this analysis, the analogy
is carried out between the natures of Avicenna and the types of HNA by
Pavlov.

162 | III
: ,
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,
.

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,

.]

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]

[OBSTETRICS AND GYNAECOLOGY]

164 | III

.., ..
[email protected]
, ,
,
() ():... ..
PECULIARITIES OF CHILDBIRTH DELIVERY FOR UMBILICAL CORD
ACCIDENTS
Akhmedova A.E., Ponomareva S.V.
Kursk State Medical University, Russia, Kursk
The Faculty of Medicine, Department of obstetrics and gynecology
Scientific Adviser(s):Ph.D. Ponomareva S.V.
Keywords:childbirth delivery, umbilical cord accidents.
: ,
Abstract: Among the main issues most important to obstetrics nowadays
are stillborn infants and fetal injuries.During the research we used a
retrospective analysis of 110 newborns with cord accidents and Color
Doppler techniques. Twin entanglement was 89,09%, true knot - 6,42%,
absolutely short cord - 3,67%. According to the Apgar score, vaginal
childbirth delivery showed worse results (at 1 minute 6,140,25
points, at 5 minutes 7,10,36 points) than Cesarean section (at 1
minute 7,20,26, at 5 minutes 7,70,28 points). Pregnant women are
to be observed since the 35th week of pregnancy.
Aim.To determine the better and more effective way of a childbirth
delivery when fetus suffers from umbilical cord accidents.
Material and Methods. This study has been conducted by a
retrospective analysis using the information of 110 newborns of Kursk
City Maternity Hospital with cord accidents. The placental umbilical cord
was studied with Color Doppler Ultrasound. Umbilical cord blood flow
was examined with Color Doppler velocimetry techniques.Most of the
women were first pregnant (59,26%). Spontaneous vaginal delivery of
childbirth was observed in 61 cases (55,45%), the programmed
childbirth delivery was 16,36%. Cesarean section was made to 31
pregnant women (28,18%). Among them planned childbirth delivery
dominated because of combined indications (breech presentation, large
fetus size, postmaturity, scar on a uterus).
Results. The most common cord accident is long umbilical cord or twin
entanglement (89,09%), then true knot (6,82%), and absolutely short
cord (4,09%) go. When natural vaginal childbirth delivery took place the
average evaluation of newborns according to the Apgar score was much
lower (at 1 minute 6,140,25 points, at 5 minutes 7,10,36 points)
than after surgical childbirth delivery (at 1 minute 7,20,26 and at 5
minutes 7,70,28 points). Besides, the number of newborns with
moderate asphyxia was 2,5 times less if cesarean section had been
made. After urgent surgeries neonatal maladjustment syndrome was
observed more times than after planned surgeries.
Conclusion. Pregnant women with cord accident are to be referred to
high risk group and should be observed dynamically since the 35th week
of pregnancy. The Doppler ultrasound method is capable of identifying
umbilical cord accident prenatally and can determine the differentiation
tactics of a childbirth delivery according to the blood flow impairment.

,
.
., ..
[email protected]
, ,
,
.
() ():*... ..
THE EPIDURAL ANESTHESIA AND OXYTOCIN INFLUENCE ON SLOW
LABOUR OUTCOME.
Tsapieva E.O.,Abashidze A.A.
Peoples' Friendship University of Russia, Russia, Moscow
The Faculty of Medicine, Department of obstetrics and gynecology
Scientific Adviser(s):[Ph.D. Smirnova T.V.

Keywords:slow labour, epidural anesthesia,labour outcome, oxytocin

: ,
, ,
Abstract:The goal of the research is the analys of slow labour outcomes,
in dependance of epidural anesthesia application and oxytocin
introduction.
: ,
,
.
: 1.
.
2.

.
: ,
, ,

.
25 , 2010
. 49
,
.
27 , 59%,
41%.

29%,

71%.
80% kiwi - 20%. 29
( 59,1%) ,
13
( 44.8%), - KIWI
7 (24,1%), 9 ( 31.1%). 20
(40,9%) .
1 (5%) , 19
(95%)

24 (49.0%)
.
(n-3),
,
33.3%, 66,7 %.
( n-5)
20%, 60%
, KIWI 20%. 16
.
44% , 66% ,
33%,
KIWI 66%.
:

.
,
, .

. -.
.., ..
[email protected]

.., ,
, 1
() ():., ... ..
METABOLIC SYNDROME FROM THE PERSPECTIVE OF OBSTETRICS AND
GYNECOLOGY.
Belomyzova A.Y., Mochalova D.O.
First Moscow Medical State University I.M.Sechenov, Russia, Moscow
The Faculty of Medicine,Department of Obstetrics and Gynaecology
Scientific Adviser(s):Doctor of Medicine, M.D. Sosnova E.A.

 . , , , 2011 | 165
Keywords:Metabolic syndrome, fatal quartet, infertility, deficiency of
progesterone, retardation intrauterine growth syndrome, ""endocrine
programming""
: , ,
,

Abstract:Metabolic syndrome is a combination of different metabolic

disorders which are the risk factors of cardiovascular complications. The
main symptoms are visceral obesity, insulinresistance, dislipidaemia,
hypertension, so called fatal quartet. This disorder is essential in
obstetrics and gynecology because it leads to infertility, fetus
abnormalities, irregular menses. Mothers disorder may influence the
infants in future endocrine programming. However there are many
unsolved questions.

/ ,
.

Lang 1922 . -
..
1970

.
:
- ,
/
,
,

.
,

,

, .

,
, .
II : I
(, , , ); II

.
.

-.
,

,
,
.

,

( , , ,

.),

(, ,
, .)
(, ,
),
( ,
, , ),
.

.

,
: (
1200 ), ,
, .

(, ),
( , , -,
1-,
-),

(, , ,
), ().

(), -
( , , ).

: ,
( , 1 ,
.),
.
:
,
,
,
.

..
[email protected]
, ,
,

() ():..., ..
DIAGNOSIS AND TREATMENT OF PRETERM PREMATURE RUPTURE OF
MEMBRANES
Ivanova A.
Peoples' Friendship University of Russia, Russia, Moscow
The Faculty of Medicine, Department and Gynecology with course of
Perinatology
Scientific Adviser(s):Totchiev G., prof. PhD
Keywords:premature rupture of membranes, premature birth, neonatal
complications, perinatal deaths, modern methods of diagnosis,
biochemical markers
: ,
, ,
, ,

Abstract:Nowadays, diagnosis of preterm premature rupture of
membranes is an acute problem of modern obstetrics. The urgency of
diagnosis is related to its adverse effects, such as premature birth, high
risk of neonatal complications requiring hospitalization in the intensive
care unit. Preterm premature rupture of membranes is responsible for
18-20% of perinatal deaths. We conducted a retrospective analysis of 40
case histories of women with a suspicion of having premature rupture of
water.
We proved that the use of traditional diagnostic methods are not
sufficiently informative, their use more than one hour after the
expected premature rupture of membranes does not make sense and
there is a need to introduce modern methods of diagnosis based on
identification of biochemical markers that would contribute early
diagnosis and timely beginning of treatment.

().

: ,
,
. ,
18-20% (CauchyAB,
RobinsonJN, NorwitzER. Contemporary diagnosis and management of
preterm premature rupture of membranes. RevObstetGynecol.
2008;1(1):11-22.).
:

.
:

), ,
,

.

166 | III
: 40
,
10.01.2010 21.07.2010 ( 201 )
25.
, :
; ; ;
,
;
;

; ;
:
1)
16 (40%)
3 ,
.
2)
5 (12,5%)

,
.
3)
7 ( 17,5%)


( 7 )
4)
2 (5%) 23 24
.

. ,
, . 7 5
. 28

6 . ,

.
:
1)

(,

, 1

(G.C.DIRenzo, L. Cabero Rouraand the European Association of

Perinatal Medicine).
2)


,
.
3)

,
.
4)

,
,

,
, ,
.

..
[email protected]
,
,
() (): .,
..
THE CHOICE OF OPTIMAL DELIVERY IN BREECH PRESENTATION
Lysova A.N
Samara Medical Institute REAVIZ, Russia, Samara
The Faculty of Medicine, Department of obstetrics and gynecology
Scientific Adviser(s):candidate of medical science assistant
O.B.Neganova
Keywords:a breech presentation, external cephalic version, caesarean
section

: , ,

Abstract:The rate of breech presentation is near 2,7-5.4%. The perinatal
mortality breech presentation is higher in 9 times as compared with
cephalic presentation. There can also be the premature dis-charge of
amniotic fluid, powerless labor, fetal hypoxia. The main idea of the
work: the justification of optimal delivery in breech presentation. We
analyze the follow of the childbirth in breech presentation in Samara
regional maternity hos-pital. There were 125 cases since 2008 to 2009.
Among them: 6 vaginal birth, 119 cesarean delivery.
There were 119 delivery by caesarian section. The correlation between
plan labor and urgent labor is 1:1. In neonatal period we found 40 Newborn with different illnesses and complications.
So, labor in breech presentation are the pathologic ones. With
increasing of delivery by caesa-rian section the number of perinatal
illness reduce. That is why it is necessary to choose the plan delivery by
caesarian section in order to reduce the number of prenatal
complications.

2,75,4%.

9 . 22,5 ,
,
- , ,
, ( .,. ..,
.., .. 2009 .).

10 - 13,
3 - 8 , .
:

.
.
-
2008 2009 (125
).
. 125
6 , 119
.
6,3%.

: 100%
, 66%,
65% .
119 .

1:1.
69
.
: 50 (72,4%),
27(39%), 30(43,4%), 4 (5,7%),
6 (8,6%), 20 (28,9%).
40
:
20(50%), -15(37,5%), 4 (10%),
3 (7,5%), 1 (2,5%).
6
.

.
. ,
.

-
.

, .

. .
.., ..
[email protected]

 . , , , 2011 | 167

.., ,
, 1
() ():., ... ..
SYMPHYSIS PUBIS DISFUNCTION FROM THE PERSPECTIVE OF
OBSTETRICS AND GYNAECOLOGY
Mochalova D.O., Belomyzova A.Y.
First Moscow Medical State University I.M.Sechenov, Russia, Moscow
The Facultty of Medicine, Department of Obstetrics and Gynaecology
Scientific Adviser(s):Doctor of Medicine, M.D. Sosnova E.A.
Keywords:Symphysis pubis disfunction, relaxin hormone, pelvic pain,
traumatism in childbirth, methods of delivery
: ,
, , ,

Abstract:During pregnancy there is a slack softening of pelvic joint and

stretching of symphysis pubis, that facilitates passing the fetus through
the bones of pelvis. In some cases such changes go the physiological
limit and then excessive relaxation of symphysis pubis or even its
rupture arise, which accompanied by pain syndrome. Disfunction of
symphysis pubis may result in different complications of mothers and
their children.Thats why obstetrician-gynecologists should choose
appropriate methods of delivery and should consult doctors of other
specialties (neurologists, surgeons, traumatologists, orthopaedists).
,

.
.
,

,
.
,

.
,

.

, ,
.
, ,
, , .

(
)
,
.

,
.

, - ,
,

.
,
. ,
,
.

.
-,
-,,, ,
.

..
[email protected]
, ,

,
() (): ,
..
PERINATAL ASPECTS AND THE RATE OF ABDOMINAL DELIVERY
Chyvatkina E.S.
Samara Medical Institute REAVIZ, Russia, Samara
Medical faculty, Department of obstetrics and gynecology
Scientific Adviser(s):candidate of medical science, assistant
O.B.Neganova
Keywords:perinatal mortality, caesarean section, indications for
operation.
: , ,

Abstract:The caesarean section is the most extended delivery nowadays.
In 2006 the rate of abdominal delivery in Russia was 18,4%
The main idea of the work: to analyse the rate of abdominal delivery,
the indications for this operation and perinatal mortality since 1990 to
1996 and since 2000 to 2006 in Samara re-gional maternity hospital.
The rate of abdominal delivery during these 14 years was 13,2% since
1990 to 1996 and 22,4% since 2000 to 2006. The perinatal mortality was
8,28 and 3,84. The main investigations for the caesaren section in
1990-1996 were senior primipara (34,2%), malpresentation (24%),
powerless labor (23%), uterine scar (15%), myopia (10,5%). In 2000-2006
the main investigations were uterine scar (20,3%), powerless labor
(18,5%), con-tracted pelvis (11,5%), breech presentation (6,7%), myopia
(7%), gestosis in the second half of pregnancy(6,3%). During the last 14
years the number of abdominal delivery increase in 1.7times and the
number of perinatal mortality reduce in 2.2 times. So, with the
increasing of abdominal delivery in 1.7 times the perinatal mortality
reduce in 2.2 times. he rate of caesaren section depends on the number
of women with different complication during the pregnancy or labor.
The main investigation for the caesaren section in 2000-2006 is uterine
scar.
()
.

,
,
, , ,
,
. 2005 17,9%
( .. 2006 .), 2006 18,4% ( .. 2008 .).


1990-1996 2000-2006 .
,
14 .
13,2%
22,4% .

8,28 3,84.

.

: (34,2%),
(24%),
(23%), (23%), (15%),
(10,5%).
:
(20,3%), (18,5%),
(11,5%), (10,1%),
(6,7%), (7%),
(6,3%).


. 14
1,7 ,
2,2 .

(, ) (30,2%).
() (28,3%),
(22,64%).

168 | III

(,
)
(62,6%), (25,3%),
(7,5%).
, 6 1,7

2,2 .

,

.

.., ..,..
[email protected]

.
() (): ..., ..
THE EFFECTIVENESS OF THE REHABILITATION OF WOMEN WITH
CHRONIC ENDOMETRITIS AFTER NONDEVELOPING PREGNANCY
Chymba A. A. ,Klychmamedova G.B., Gulmuhammedova J. C.,
Department of Obstetrics and Gynecology with course of Perinatology
PFUR
Moscow
Scientific Adviser(s): professor, M.D. Totchiev G.F.
Keywords: Chronic endometritis, nondeveloping pregnancy.
Abstract: Chronic endometritis occupies an important place in the
structure of inflammatory diseases of the pelvic organs and still the least
understood. In modern conditions the controversial issues concerning
the treatment of chronic endometritis remain unresolved. The purpose
of this paper is to examine the effectiveness of the rehabilitation of
women with chronic endometritis after nondeveloping pregnancy
revealing effects of antibiotic therapy and hormone therapy on
becoming pregnancy
()
,
30-35% ,
.


, : ,
, .
:

().
:

.
.


.

.
:

75
,
40 64 2008-2010 .

.
:

30
35 - 32%, 20-25 26-29 25%.
,
33,33% , 46,67%,
22,67%,
13% . 1

77,34% ( n=58 ), - 22,66% ( n=17)

.

:
Escherichiacoli
(20,8%),
Enterococcusfaecalis
(19,7%),
Staphylococcusaureus
(19,7%),
Candidaalbicans (7,6%).

,
. 75
54, 22,
24, 8 .
20
, 8 .
21,
4 .
2008-2010
26 (35%), 5 (6, 7 %),
20 (26,6%) , 1
(1,3%).
:
,


.
3-6

. , ,
.
,
. ,

,
.

. ,
,
.

.., .., .., ..
[email protected]
, ,

() (): ...,

ASSESSMENT OF HEART RATE VARIABILITY AS A METHOD OF

FORECASTING THE BEGINNING OF LABOR
Dmitrieva, SL, Khlybova SV, Tsirkin VI, Khodyrev, GN
Kirov State Medical Academy, Russia, Kirov"
Department of Obstetrics and Gynecology IPO
Scientific Adviser(s):MD, professor Khlybova Svetlana V.
Keywords: heart rate variability, pregnancy, childbirth
: , ,

Abstract: Question of changing the parameters of heart rate variability

(HRV), reflecting the state of the autonomic nervous system (ANS), in
women during the gestational process so far not been adequately
investigated.The purpose of this study - the study of the dynamics of
HRV pregnant women during gestation and before delivery (1.5 per day
before birth).

,

.
(),
(),

.

 . , , , 2011 | 169
.
- ,
,
.

( 5-1
). .

23 40

(17-21- ), 11 I
(7,50,6 ; 24,62,2 ), 13 II
(28,51,0 ; 27,31,3 ), 15 III
(34,40,5 ; 23,20,9 ) 13
(39,40,3 ;
26,00,7 ).
,
,
<0,05. . I
14 ,
, , ,
. II III

19 22 ,
, ,
, II
. 5


, 34-38 .
. ,
5 , .

,
- . 1
.

.

.
.., ..
[email protected]
, ,

,
() (): ... ..
THE ROLE OF ULTRASOUND MARKERS IN THE PREDICTION OF
MISCARRIAGE.
Dubrovina I.N, Avetisyan A.A.
Kuban State Medical Univercity, Russia, Krasnodar
The Faculty og Medicine, Department of radiodiagnostics and
radiotherapy
Scientific Adviser(s): k.m.s. Macukhina T.B.
Keywords: noncarrying of pregnancy, pathology of pregnancy, first
trimester, ultrasound predictors
: ,
, ,
Abstract: A retrospective study of ultrasound protocols in two groups
(with the progression of pregnancy and miscarriage of pregnacy) of
patients admitted to hospital with a threatening miscarriage in the first
trimester revealed the next ultrasound predictors: fetal bradycardia (less
than 90 beats per minute), lagging the the crown-rump length by more
than 10 days of gestation, the area retrohorialnoy hematoma is over 1 /
3 of the chorion.
:
.

: 50
,
6 12 .
: ,
(n=30,
288 ), ,

(n=20, -284 ).
,
, 7
13 .
:
12720 (
100), - 9410. -
() 100%,
60%
10 .
, .
80 %,
100% ;
1\5 1\3 ,
1\2, 40%
1/3 2/3
. 224 ,
2 - 204 ,
(25%);
18% ,
20%.
:

10 , (
90 ),
1/3 .

.

-1
,

., ..
[email protected]
, ,
,
() (): ... ..
DISTRIBUTION OF CLAUDIN-1 IN GLANDULAR EPITHELIAL CELLS OF
NORMAL PROLIFERATIVE, HYPERPLASTIC AND NEOPLASTIC
ENDOMETRIUM
Shchelokova E.E., Kovyazin V.A.
Peoples' Friendship University of Russia, Russia, Moscow
The Faculty of Medicine, Department of pathology
Scientific Adviser(s):Ph.D. Babichenko I.I.
Keywords: endometrium, claudin-1
: , -1
Abstract:
Claudin-1
expression
was
assessed
using
immunohistochemistry in glandular epithelial cells of normal
proliferative, hyperplastic and neoplastic endometrium. Claudin-1 can
be used as a criteria for early diagnostic methods to distinguish
neoplastic or proliferative process in epithelium of endometrium.
:

.

,
. ,

,
.
,
, - .
,

170 | III
, ,
,
.

,
,
.
: -1

.
.
. 115 36
, 32 , 13 - , 34
.

.
-1
(LabVision).

(BioGenex).

.
.

: .

.

. ,

, .
: ,

-1 ,
, ,
,
. ,

. , -1

[ - ,
,
.]

[]
[PHARMACY]

172 | III
IN VITRO AND COMPUTATIONAL ANALYSIS OF AURORA INHIBITORS.
Zoltn Nemes1,; Zoltn Horvth3,; Csaba Kis Szntai3,; Gyrgy Kri2,3,;
Lszl rfi1,3,
1Department of Pharmaceutical Chemistry, Semmelweis University,
Budapest, Hungary
2Pathobiochemistry Research Group of Hungarian Academy of Sciences,
Department of Medical Chemistry, Semmelweis University, Budapest,
Hungary
3Vichem Chemie Research Ltd., Budapest, Hungary
Introduction: Up to 2010 there are 8 FDA approved kinase inhibitors on
the market with known target kinases. Most of them are multi kinase
inhibitors and can affect on several tyrosine or serine/threonine kinases.
These drugs are among the most up to date drugs in oncology. They are
very promising but even the most specific ones have very
disadvantageous side effect profile.
Aim: We wanted to develop, characterize and test a series of indolin-2on (Sunitinib analogue) kinase inhibitors which can be easily connected
to organ specific drug delivery systems via peptide bond. From the
possible carrier systems we are focusing on integrine selective RGD
peptide sequences.
Our assumption is that with the use of such peptide sequences aided
kinase inhibitors one could reach and affect on the target organs
selectively and cause less side effects due to the lower systemic
distribution than the free dugs.
In this paper we would like to present the first stage of this project: the
kinase inhibitor selection. The kinase inhibitor set for the studies was
provided gratis by Vichem Chemie Research Ltd2.
Materials and methods: In silico experiments were performed with
Yasara version 10.4.11. PDB files for cross docking experiments were
downloaded from the RCSB protein data bank (1mq4; 3g0e).
In vitro enzyme titrations and Ki value determinations were
performed with IMAP-TAMRA technique in 384 well plates. Inhibitor
solutions were added to wells with Tecan Freedom Evo 150/4 robot.
Fluorescence polarization was measured with Analyst GT. Aurora A was
ordered from Proteros. Biostructure, Munchen.
Results: In cross docking experiments we have determined Ki values of
30 kinase inhibitors.
With enzyme titration experiments we determined the
optimal parameters for the IC50 measurments.
We have determined the in vitro IC50 values of 30 kinase
inhibitors at 5 ATP concentrations (Km ATP/9, Km ATP /3, Km ATP, Km
ATP*3, Km ATP*9).
We have calculated the Ki values of these kinase inhibitors
from the experimental IC50 values according to the Cheng-Prusoff
equation.
We compared the in silico and the in vitro Ki values. For
66.6% of the kinase inhibitors we were able to determine the Ki values
in silico with a lower difference than +/-1,5 log unit from the in vitro
values. 33.3% of the results were out of the acceptance range.
We have also determined these in silico parameters for the
possible metabolites of several hypothetical drug peptide carrier
systems.
Conclusion:
Comparing all the data we have described the QSAR of the kinase
inhibitors. From the QSAR results we were able to determine the best
indolin-2-on kinase inhibitors for peptide based organ specific drug
targeting systems.
Acknowledgement:
The authors would like to thank to Ed E Moret Universiteit
Utrecht The Netherlands for the license of YASARA.

II
..
[email protected]
, ,
,

() (): ... ..

COMPARATIVE
PHARMACOECONOMICAL
AND
PHARMACOEPIDEMIOLOGICAL
RESEARCH
OF
ARTERIAL
HYPERTENSION AND DYSLIPIDEMIA THERAPY IN PATIENTS WITH
DIABETES MELLITUS IN INPATIENT DEPARTMENTS OF RUSSIA AND
LATVIA
Anosov I.S.
Peoples' Friendship University of Russia, Russia, Moscow
The Faculty of Medicine, Department of Management and Economics of
Pharmacy
Scientific Adviser(s): Ph.D. Gushina Y.S.
Keywords: pharmacoepidemiology, pharmacoeconomics, diabetes
mellitus, arterial hypertension, dyslipidemia, in-patient treatment.
: II , ,

,
,
.
Abstract: Diabetes mellitus (DM) is associated with markedly increased
cardiovascular complications (CVC) which also represents an
independent risk factor for enhanced mortality. Reduction in this burden
requires a multifactorial approach, encompassing control of glycemia
and reduction in most important cardiovascular risk factors: arterial
hypertension and dyslipidemia. The aim of our work is undertaking the
comparative pharmacoepidemiological and pharmacoeconomical
research of the main CVC risk factors therapy in patients with DM in
inpatient departments of Russia and Latvia.
() II

()
. II
. ,
-
()
().
(IDF)
2025 300 .
, ()

. ,


.

, ,
II ,

() .
.

II () ,

.
.
;
.
: ,
(
II );
II ;
;
()
( , -).

.
:
5,5-6,5 /, ()
4,5 /, 130/80
...
. II
.
-

 . , , , 2011 | 173
91% 85% .
:
17,8% 18,4%; 41,7% 44,0%;
40,5% 37,6% .


: -
() + (); () + ;
- () + + . II
: + (22,7%),
(18,2%).
: (23,9%), +
(16,3%).
, , 90% ,

.
,

.
. -
II
, .
, ,
,
.

..
[email protected]
, ,
, ,

() (): . . . .., .. .
..
PHARMACOGNOSTICAL STUDY OF SOME SPECIES OF MEDICAL PLANTS'
HAIRY ROOTS
Babaeva A.Y.
Peoples' Friendship University of Russia, Russia, Moscow
The Faculty of Medicine, Department of botany, plant physiology and
agrobiotechnology
Scientific Adviser(s): Ph.D. Vandyshev V.V.,Ph.D. Kuzovkina I.N.
Keywords: hairy roots, identification, key-determinant
: , ,
-
Abstract: The aim of this work was to examine special features of some
species of hairy roots and to create the identification guide for this kind
of raw material.

, . .

.
,
, , ..

, ,
.
. -

-
.
. :
- 13
; - Rubia tinctoria, Senecio
platiphyloides, Sophora sp., Salvia officinalis;
Ruta
graveolens, Salvia officinalis Senecio platiphyloides;
-
.

-
, ,
, .
.
Sophora sp, Rubia tinctoria
.
.
Ruta
graveolens, Hedysarum theinum, Salvia officinalis, Rauwolfia serpentina,
Rubia tinctoria, Sophora sp. -1.
Canon
power shot A 550
.
.
.

.
- - 4-
. ,

. -
4 .
XII
( 42-0067-07). Escherichia coli ,
Staphylococcus aureus - , Pseudomonas
aeruginosa
, Candida albicans .
,
.
4 ,

.
-

, .

.
,
,
.
.
Rauwolfia serpentin L., Ruta graveolens L.,
Hedysarum theinum, Thermopsis sp., Salvia officinalis L., Rhodiola rosea
L., Rubia tinctoria, Sophora sp., Senecio platiphyloides Somm. et Levier.
Scutellaria baicalensis Georgi .
-
.

.
.

XII.
-

.., .., .., ..
[email protected]
, ,

. . . , , .

() (): ... .., ...,
..

174 | III
DEVELOPMENT OF METHODS OF ANALYSIS OF SOLUTIONS OF
BIOLOGICALLY ACTIVE GLYCOPROTEINS FOR QUALITY CONTROL OF
DRUGS BASED ON THEM
Golubtsova T.A., Uspenskaya E.V., Yamskova V.P., Syroeshkin A.V.
Peoples' Friendship University of Russia, Russia, Moscow
Koltzov Institute of Developmental Biology, Russian Academy of
Sciences, Russia, Moscow
The Faculty of Medicine, Department of Pharmaceutical and
Toxicological Chemistry
Scientific Adviser(s): Ph.D. Uspenskaya E.V., Ph.D. Syroeshkin A.V.

Keywords. Bioregulators, low angle light laser scattering, size spectra,

integral characteristics, giant heterophase clusters, dynamic laser
scattering

.
,

, ,
,
Abstract. In this study glycoproteins of group of tissue-specific
membranotropic bioregulators of animal origin were examined.
Bioregulator was isolated by extraction from liver of rats. We
investigated the structure of aqueous solutions of bioregulyator using
low light scattering and determined particle size of bioregulator by
dynamic light scattering. The obtained results give an opportunity to
make suggestions about possible methods of analysis of drugs on the
basis of glycoproteins.
.
,

, .
:
.
.
,
.

,
Wistar,
.
.
0,110-1 /,
0,110-3 /, 0,110-6 /, 0,110-9 /, 0,110-12 /
( -).
(LALLS)
() ,
MasterSizer 3600Ec
Malvern.
: , ,
.
(DLS) ,
Zetasizer Ver.6.12., Malvern.
: 0,0002/,
0,0010/, 0,0100/, 0,08105/.
Millex 0,22 .
.
50. 38,5%.
110-9 /,
0,110-12 / 50
31%. 0,110-6 /
3 : 10 , 25 50 .
2,18%, 7,17% 21,3% .
0,110-3 / 10
0,3%, 25 4,54% ,50
15,1%. 0,110-3 /
10 0,8%, 20 6,77%, 50 29,4%.
(Vc).
0,110-12 / Vc 0,0005%. Vc 0,0007%,
0,0014%. 0,110-3 /.
0,110-1 / Vc 0,0004%.
. 0,110-12
/ 0,110-9 / 0,0045

0,0040. 0,0130 0,0180

0,110-6 / 0,110-3 / .
0,110-1 /
0,0084. (SSA).
0,110-12 /
0,1246 -1.
SSA : 0,110-9 / 0,1360 -1, 0,110-6 /
0,2080 -1. 0,1.10-3 /
0,1646 -1, 0,1.101 / 0,1919 -1.

DLS.
.
0,0002 / 119,7 , 0,0010
/ 49,69 , 0,0100 / 359,4 ,
0,08105 / 482,3 .
. ,
,
,
.

.., ..
[email protected]
, ,
, ,

() (): ..., ..
TO THE DISCUSSION OF STANDARDIZATION OF PROPOLIS
Danilina E.A., Babaeva .Y.
Peoples' Friendship University of Russia, Russia, Moscow
The Faculty of Medicine, Department of botany, physiology and
agrobiotechnology with course of pharmacognosy
Scientific Adviser: Cand.Sc.Biology decent Babaeva .Y.
Keywords: propolis, pollen, standardization, medicinal, identification,
authenticity, solvent, microscopy
:
, , , ,
, , ,
Abstract: The choice of optimum solvent for propolis, the organoleptical
study and the microscopy of propolis were carried out. Various kinds of
pollen were discovered in microscopic preparations from propolis.
Criterions of standardization of propolis on pollen were offered.
,
.
5%.
,
, , ,
.
11 :
, ,
. ,
, ... .
.. .
.

,
-
( 28886-90 ).
. ,
,
.
.
. 0,15 0,2
60% 5
.
.
, ,

 . , , , 2011 | 175
.
.
-1 -12

10. Canon Power

Shot A 460/5,0.
.
. , ,
.
60% , ,
.

,

.
2 . ,
(
, ) .
,
(, ).
Tilia. ,

.
.
.

, .
Asteraceae.

Centaurea.
Fabaceae, Cannabaceae, Malvaceae, Dipsacaceae,
Limoniaceae, Onagraceae, Brassicaceae, Polygonaceae.

. ,
.
,
.
Betula, Alnus Pinus.
.

, .
.
,
.
,
.

,
. ., .., .., .., ..
[email protected]

..

,

() (): ... .
CONDITIONED REFLEXES PLACE PREFERENCE IN RATS UNDER THETHE
INFLUENCE OF OF EXTRACTS ALKALOIDSODERZHASCHIH GRATIOLA
OFFICINALIS, CHAMAECYTISUS RUTHENICUS, AND NUPHAR LUTEA
Docalo V.E, Bukov A.V,Kuznetsova I.A,Voronin M.YU
Saratov State Medical University named after V.I.Razumovsky
The Faculty of Pharmacy, Department of General Biology, Botany and
Pharmacognosy
Scientific Adviser(s): Ph.D. Voronin M.YU
Keywords: Student, work, prize, science
: ,,,
Abstract. A comparative evaluation of addictive potential
alkoloidosoderzhaschih extracts broom Russian (Chamaecytisus
ruthenicus), Hauran drug (Gratiola officinalis) and egg capsules of yellow

(Nphar ltea) using the technique of conditioned reflexes (SD) in

laboratory albino rats by initially balanced choice chambers (Khabriev,
2005 ).Thus, the results of our study were revealed new biological
properties of these extracts Chamaecytisus ruthenicus and Nphar
ltea,namely, their addictive properties, the most pronounced in
Gratiola officinalis. Conditioned reflexes place preference in rats under
thethe influence of of extracts alkaloidsoderzhaschih Gratiola
officinalis,Chamaecytisus ruthenicus, and Nphar ltea.As a result of our
investigations were opened by new biological properties of these
extracts Gratiola officinalis and Nphar ltea ,it is their addictive
properties, the most pronounced in Chamaecytisus ruthenicus.

(Chamaecytisus ruthenicus), (Gratiola

officinalis) (Nphar ltea)
()
(, 2005).
d-, d-,
; , ,
.;
( , 1950; , 2007).
.
, XI.

(57,7%
),
(33,5% ).
( 519,4 . 900 .
301,7 . )
(P=0,0002) - (P=0,0002).
14 19
5
.
. ,
,

59,4% .
30%
.
(<0,005). ,
,

(51,5% ),
.
,
.
35,6% , ,
46,7%.

, .
,

.
, ,
,
,
.
. ,

,
,
.

.., .., ..
[email protected]

176 | III
, ,
, ,

() (): ... .., ...
..
STUDING OF ACCUMULATING OF HYDROXYCINNAMIC ACIDS
DERIVATIVES AND POLIFRUCTANS IN RHIZOMATA CUM RADICIBUS
ECHINACEAE PURPUREAE (L.) MOENCH DEPENDING ON OVERGROUND
PARTS REMOVAL TIME
Zvereva V.I., Babaeva E.Y.Kopilova I.E.
Peoples' Friendship University of Russia, Russia, Moscow
The Faculty of Medicine, Departament of botany, plant physiology and
biotechnology with course of parmacognosy
Scientific Adviser(s): Ph.D. Babaeva E.Y., Ph.D. Kopilova I.E.
Keywords: Hydroxycinnamic acid, polifructans, hydrolysis, quantitive
determination, Echinacea.
: , ,
, , .
Abstract. The goal of this work was to study the number of
hydroxycinnamic acids derivatives and polifructans, depending on
overground parts removal time.


, ,
.
.


(Echinacea purpurea L.)
. ,
.
.
(,
, );
(

),

.
, ,
.
.


.
. 2009 2010 .

3 .

( 64-4-122-95,
1,5%).
,


.
,
(,
, ),
.
.
. ,

. ,

2009 .

( 4,33%)

(1,95 2,01%).


,

19,42%. 2010 .
.

,
.
1,7%.

2010 ., , ,

(
).
15,27%.

( 8,48%).
.

.

.
.

..
[email protected]
, ,
,

() (): ... ..
DEVELOPMENT OF STANDARDIZATION METHOD OF SEMI-SOLID
DOSAGE FORM WITH GRAPE EXTRACT
Kaplun M.B.
Peoples' Friendship University of Russia, Russia, Moscow
The Faculty of Medicine, Department of General Pharmaceutical and
Biomedical Technology
Scientific Adviser(s): Ph.D. Suslina S.N.
Keywords.Standardization, gel, grape extract, phenols
. , , ,

Abstract. The goal of our work was development of standardization

method of grape extract phenols in semi-solid dosage form like gel. We
used the spectrometry method. The methods of quality control in water
with Folin-Ciocalteu reagent (746 nm, pirogallol like standard) and
method in alcohol with Gallic acid like standard (267 nm) showed that
the adjuvants in gel had an influence on determination. The quality
control method with 2% aluminum chloride in alcohol was used for gel
standardization.
.


, .

,
-
.
, ,
,
,
.

.
,
,
.
,
.
.


.

 . , , , 2011 | 177
. :
- ,
, - ( ).
: Folin-Ciocalteu (Merck),
2% 96% ;
(Sigma-Aldrich), , ,
(Fluka).
Lambda 2 (Perkin Elmer).
.
( , ),
, .
,

Folin-Ciocalteu ( 746
), .

, - .
-
,
, Folin-Ciocalteu
.

40% 267
.
- . ,

2% 96%
420 , XI.
(413 )
(431 ).
, -,
. ,

.
.
.
,
,
2%
420 .

QI & JIN THE

HISTORY OF WHOO.
.
..
[email protected]
, ,

,
() ():
. .
,
THE TEENAGE LINE QI AND JINOF THE KOREAN COSMETICS THE
HISTORY OF WHOO. POSSIBILITIES OF APPLICATION FOR THE
EUROPEAN TYPE OF A SKIN.
Lee A.V.
Peoples' Friendship University of Russia, Russia, Moscow
The Faculty of Medicine,
Department of Biochemistry
Scientific Adviser(s): Kuznietsova O. M. PhD
Keywords: the Korean cosmetic The history of Whoo, the teenage line
Qi and Jin
: " ",
Qi & Jin
Abstract. The Work Purpose: Analysis of the impact of the Korean
cosmetics market "The History Of Whoo" teen lines "Qu & Jin" on the
skin of the European type. Materials and Methods: Cosmetics "The
History Of Whoo", teen line "Qu & Jin", contains in its structure: antlers
hood of young Siberian deers, asparagus extract,angelica extract, root
extract of a wild ginseng, wild thyme extract, snow lotus's extract, aloe

extract, chamomile extract, jojobas extract, chrysanthemum extract. The

duration of the experiment - 28 days during winter. The experiment
involved adolescents aged 15-16 years (n = 10, sex-female). 1 Group Skin type - mixed - 3 persons. 2 Group - Skin type - bold - 4 persons. 3
Group - Skin type - dry - 2 persons. 4 Group - Skin type - sensitive - 1
person. For each of the teens were picked up tools for cleansing, lotions
and tonics according to skin type. Results and Conclutions: After four
week observation we can note a significant improvement in the skin of
all adolescents, without exception.
According to the study, Korean cosmetics The history of Whoo line
Qi & Jin can be recommended for adolescents with European style
skin.
.
The history of Whoo Qi & Jin
.
,
.


, : ,
, , . LG
Household & Health are.Ltd. The history of
Whoo
Qi & Jin. ,
, ,
,
-,
.
. The history of Whoo,
Qi & Jin, :
, , ,
, ,
, , , ,
. - 28 ,
.
15-16 (n=10, - ).
1 - -3 .
2 - -4 .
3 - 2 .
4 - -1 .

, .
. 4-

.
1 -
1 -2 . ,

3 -4 . , , ,
-
2 -
1 -2 . .

3 -4 . ,
50 %, ,
3 -
1 -2 . ,

3 -4 . ,
4 -
1 -2 . ,

3 -4 . , ,
.
67%
.
The history of Whoo Qi & Jin
.

178 | III
.., .., .., ...,
...., ...
[email protected]
, , ,
, , , - ,
,

() (): ... ..
AIR IONS AND HUMAN HABITATS
Mussa M.Y., Maksimova T.V., Zhuravlev A.V., Mahran M.H.M., Mostafa
A.M.T.E., Abdelaal M.O.M.
Peoples Friendship University of Russia, Russia, Moscow, FGUP
VNIIFTRI, Russia, Moscow, Egyptian-Russian University, Egypt, Cairo
The Faculty of Medicine, Department of pharmaceutical and
toxicological chemistry
Scientific Adviser(s): Ph.D. Maksimova T.V.
Keywords: ir ions, volatile organic solvents, coefficient of unipolarity
: , ,

Abstract: The experiment was done to determine the effect of volatile
organic solvents on composition of air ions in the laboratory and
amount of air ions in the classrooms, staff offices, head of departments
offices under different conditions. It was found that after switching on a
fume hood the average coefficient of unipolarity of air ions decreased
nearly to that of sanitary and hygienic norms (0,4 < 1,0).

(). ,

.

(- 2-), (N-),
- (-). (+),
(2+, +).
(N+/N-)

0,41,0 *1+.

, ,
.

, ,

.
.
-3 ( 42974-09 ,
). 16 64 .
3800 3/.
,
(N/3) ().
.
(
) 4,0.
( n = 228)
3,9; 0,7 0,5 13; 23 30
.
400,
600.
: N+ - 120 444, N- - 114
388. ,

. ,
,
,

2-3 *1+.
, ,

, .

: = 2,6 (1,15,0).
,
. ,
,

,
,
= 1,1 (0,3 2,0).
,

.

.
,
,


,
.
. ,



- .
1.
2.2.4.1294-03

.., .., ..
[email protected]
,,
, ,

() (): ... .., ...
..
STUDDING OF BIOMETRIC INDICATORS AND PRODUCTIVITY OF
ECHINACEA PURPUREA PLANT, DEPENDING ON VARIOUS FACTORS
Petrova A.L., Babaeva E.Y., Zagumennikov V.B.
Peoples` Friendship University of Russia,Russia,Moscow
The Faculty of Medicine, Department of botany, physiology and
agrobiotechnology with course of pharmacognosy Scientific Adviser(s):
Ph.D. Babaeva E.Y.,Ph.D. Zagumennikov V.B.
Keywords:
Echinacea
purpurea,biometrics,productivity,year
of
vegetation

,,,
Abstract: The goal of this work was studding biometric indicators and
productivity of plant Echinacea purpurea (L.), depending on age.

. 70 ,

,
.


.
.
,

( ),
2009 . 2010 .
20 .

 . , , , 2011 | 179
t.
.
3, 4, 5 7 . 2010 .,
, ,
,
,
.
, 3 . .
2,5 .

.
,
. 3-4 .

1,7-2,2 .
,
16,2 - 34,7%.
. 3 .
2,1 , 4, 5 7 .
1,5 - 1,6 .

, , , .
, ,
.
4 5 .
4, 5 6 .
2009 . ,
4 5 .
. 6 .
( 11,1%) .

. 6 .
II
4-5 .
,
10,8 . 4 5
. 2009 2010 .
2010 .
2010 . ,
40 . .,
.
8,8% 23,7% .
:
1,5 2,5 . 3,0-4,5 ,
, 2009 .,
. ,
, 2010 . 2,7 4,3
.
. 2010 .
3, 4, 5 7 .
.
4 5 .
2009 2010 . 2010 .

.., ..
[email protected]
, ,
, ,

() (): ..., ..
COMPARATIVE STUDYING OF GRASS OF GIPSY-WORT AND POSSIBLE
IMPURITIES AND METHODS OF THEIR IDENTIFICATION
Repina K.N., Babaeva .Y.
Peoples' Friendship University of Russia, Russia, Moscow
The Faculty of Medicine, Department of botany, physiology and
agrobiotechnology with course of pharmacognosy Scientific Adviser(s):
Cand.Sc.Biology, decent Babaeva .Y.

Keywords: grass of gipsy-wort, polysaccharids, flavonoids, tannins.

: , , ,
.
Abstract. In the present study was done a comparative studying of grass
of gipsy-wort and possible impurities to external signs, an anatomic
structure, qualitative reactions.
:
.
: ,
.
(Lycopus europaeus L.) -
(Lamiaceae).
, 2010 .


: , ,
.
(,
).

, XI .1.

1 -12 1,5 ( 10,
10, 20, 40) 10.
Olympus FE-280
Microsoft Office Picture Manager Adobe Photoshop 7.0.

-
. : NaOH,
FeCl3; HCl ., , .

. ,
, , .
- -,
,
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, 4-5(6) . 2,8
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, 1,8 , -,
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.
,
,

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,

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.
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.
() - .
, Lamiaceae, 2-8 ,

180 | III
. ,
( ),
.
, .
.
,
.
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, . .
.
.

-
.
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1:10
(III) ,

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: ,

.

GRATIOLA
OFFICINALIS L. -1
- .., .., ..
[email protected]
..
, ,
, ,

() (): ... .., ...
..
THE ANTIOXIDANT ACTIVITY OF GRATIOLA OFFICINALIS EXTRACT
CONTAINED SUM OF FLAVONOIDS ON LABORATORIAL RATS WITH
TUMOR OF LIVER PC-1
Tysin-Konstantinov G.E., Isachenko N.M., Romanteeva Yu.V.
Saratov State Medical University n.a. V.I.Razumovsky, Russia, Saratov
The Pharmaceutical Department,
Department of Common Biology, Pharmacognosy and Botany
Scientific Adviser(s): Cand.Biol.Sci. Durnova N.A., Dr.Sci.Biol. Polukonova
N.V.
Keywords: antioxidant activity, tumor, flavonoids
: , ,

Abstract. The antioxidant activity of Gratiola officinalis extract

researched on la-boratorial rats with tumor of liver PC-1.The level of
MDA, catalase and superoxide scavenger activity were increased. The
increase level of lipids peroxidation is protective mechanism initiated
apoptosis of cancer cells.

,
, ,
,
.
:
(Gratiola
officinalis)
-1.
.
.
1
.
.

(); ()
(, 2000).

.
: : 5.248
/ ( 1.933 /); 0.369 (
0.175 ); 7.188 ( 4.527 ).
171%
,

, ,
: 111%,
59%.
: , ,
.
() ,
.
, .

Z MAYS L.
.., . ., .., ..
[email protected]
. ..
, ,
. ,

() (): ... .
ANALYSIS OF THE TOXICITY OF THE EXTRACT CONTAINING
FLAVONOIDS ANTHOCYANIN MAIZE ZEA MAYS L.
Shcherbachenko A.S, Almyashev R.S., Turina, L.M, Fedorova I.A
Saratov State Medical University named after V.I Razumovsky, Russia,
Saratov
Faculty of Pharmacy. Department of General Biology, Botany and
Pharmacognosy
Scientific Adviser(s): Ph. D. Polukonova N.V
Keywords: Colorant, anthocyanin, toxicity, extract, biological objects,
culture of cells, experiment.
: , , , ,
, , .
Abstract: The purpose of this study - to study the toxicity of the extract
anthocyanin maize Zea mays L. on different groups of biological objects chironomid Chironomus plumosus, Ch. riparius, the fish Danio rerio and
culture of embryonic cells, rhesus monkeys. Preparation of alcoholic
extract of maize anthocyanin Z. mays L. was carried out from dry raw
materials. As laboratory animals used in mosquitoes Ch. plumosus and
Ch. riparius, aquarium fish Danio rerio and the tests were conducted on
the culture of embryonic cells rhesus monkeys. The results were
analyzing it. The purified alcohol extract of maize anthocyanin can be
considered nontoxic.
Zea mays L.

 . , , , 2011 | 181
.
,
( ., 1995;
., 2010),

.
-
Z mays L.
- Chironomus plumosus, Ch.
riparius, Danio rerio .
Z. mays L. .

- Ch. plumosus Ch. riparius IV
.
48 ,

(, 2009). D. rerio (
2.5-3.5 , 150-250 ) (10 )
,
. (96
.) Tetra Min;
. , , .
(LC50, LC100)
- (, , 2003)
- (, 1991).
15.06.2001 511.
-
104.
.
.
, ,
, 10 ,
IV-V

.

.

,
.

.
.
. ,


.

.., .., ..., ....,
...
[email protected]
, ,
,
,

() (): ... .., ...

..
PHARMACEUTICAL EQUIVALENCE ASSESSMENT OF GENERIC
METOPROLOL SUCCINATE
Yakushev. V.A., Ananyev A.A., Zhuravlev A.V.2, Mahran M.H.M.3,
Mostafa A.M.T.E.3, Abdelaal M.O.M.
Peoples' Friendship University of Russia, Russia, Moscow
The Faculty of Medicine, Department of general and clinical
pharmacology, Department of pharmaceutical and toxicological
chemistry.
Scientific Adviser(s): Ph.D. Fitilev S.B., Ph.D. Pleteneva T.V.
Keywords:
metoprolol
succinate,
generic,
bioequivalence,
pharmaceutical equivalence, infrared spectrum, toxicity

,
,
,

,
,
Abstract: Pharmaceutical equivalence of metoprolol succinate generic
version was estimated by infrared spectrometry, high-performance
liquid chromatography and dissolution test. Adverse reactions of generic
comparing with the original drug were predicted for subsequent
bioequivalence study and clinical use. According to conducted
experiments and analysis generic would have no additional or new toxic
effects.
()
-
. 1,

(),

,

. 1,

,
, ,

25-200
,
. 3 10 %
, , , ,
, . 1 %
, , ,
, , , ,
- .
, , ,
.
, 75 .
, 500
.
,

, .
, .

, .

, , ,
1,
.



.

,
.

,
.



.
:
. -
(Varian 670-IR).
,

,
. -
,
, . (200 )
(Varian, - ProStar 325.44
280 , ProStar Dynamax, ProStrar 400.26,
Discovery C8 1504,6 ).
(100, ,

182 | III
)
-
(
).
( 10 )
.
in
vitro, ,


(5%

).

.., .., .., ..
[email protected]


, "
,
() (): ... ..
TREATMENT OF PATIENTS WITH SEVERE FORMS OF ACNE BY THE
STANDARD SCHEME BASED ON INDICATORS OF MICROBIAL
CONTAMINATION OF THE ELEMENTS OF ACNE
Asaenok A.A., Silina L.V.,Shwarts N.E., Besedin A.V.
Kursk State Medical University
Federal Agency for Health and Social Development "", Kursk"
Medical Faculty, Department of Dermatology and Venereology
Scientific Adviser(s): Ph.D Silina L.V
Keywords:acne, treatment
: ,

.
, 2030%
1012 7590% 1618
.
,

.

,
, ,
,

,
.
, ,

,
.




.
47 ,
15 25 , ,
, 39
(
).

, , , , ,
,
.

-2

LACHEMA
().

m.

-.

-,
, 70%
(, , ), 31%
-
( ,
, , ), 23%
, 8%
-
.
,
(62%), ,
- (23%) ( 15%)
,
.
, Propionibacterium acnes
Staphylococcus epidermidis+Propionibacterium acnes,
,

.

Staphylococcus
epidermidis+Propionibacterium acnes ,

,
. ,

.
,
.

,


,

Staphylococcus epidermidis+Propionibacterium acnes.
, ,


,

ECHINACEA
.., ..
[email protected]
, ,
,

() (): ... ..
RESEARCHING OF MARKET OF IMMUNOSTIMULATORY DRUGS BASED
ON PLANT OF THE GENUS ECHINACEA
Zvereva V.I., Gribkova H.I.
Peoples' Friendship University of Russia, Russia, Moscow
The
Faculty of Medicine, Department of organisation and economics of
pharmacy
Scientific Adviser(s): Ph.D. Gribkova H.I.
Keywords: Immunostimulants, Echinacea, Register, producer, Immunal,
: , , ,
,
Abstract: The goal of this work was to study the market structure of
immunostimulating drugs and the ascertainment of the place of drugs
based on plants of Echinacea on the market.

 . , , , 2011 | 183

, ,

,
, .
.

, ,
.
: ,

,
,
.
:
,

Echinacea
.
.
,

2010 . , L03
.
VIDAL 2010 .,
, ,


2008 .
. ,
2010. 141
,

20% L03AA
, 31% - L0AB
, 2% - L03A 47% -
L03A .

. ,


, , .
,

. L03AA
, L03AB L03A
.
L03
,
15 90
( 60% - ).

Echinacea L03A
.
Echinacea
28% (17 ) 2010 ,
2001 (9
) , L03A
.

( 2001
2009 ) 10 - L03

. ,
L03AB .

.
. ,
L03
141 ,
.
,
Echinacea,
L03A ."

..
[email protected]
, ,
,

() (): ..., ..
COMPARATIVE ANALYSIS OF QUALITY OF LIFE OF GLAUCOMA
PATIENTS USING VARIOUS OPTIONS PHARMACOTHERAPY
Malishevskaya O.I.
Tyumen Medical Academy, Russia, Tyumen
The Pharmaceutical Faculty, Department of Management and
Economics of Pharmacy
Scientific Adviser(s): Ph.D., Knish O.I.
Keywords: Glaucoma, quality of life, international survey SF-36
: , ,
SF-36
Abstract: Glaucoma is the leading cause of irreversible blindness, visual
impairment and disability. Questions evaluating the effectiveness and
efficiency of the choice of hypotensive drugs in the pharmacological
treatment of glaucoma are of particular relevance in connection with
the emergence of the pharmaceutical market of new drugs. Modern
methods of analysis of drug therapy is to assess the quality of life, which
refers to the integrated assessment of physical, mental and social
functioning of the patient, based on his subjective perception.
,
, .

(), , ,

.
,
,
(),
,
,
.
:

.
.
50
. (25 )

0,5% 2 + 1% 2 .
(25 )
(/) 2 .
3 .
SF-36
Short Form HEALTH STATUS SURVEY.
,
.
11 36 .
( 0 100)
8 ;
.
-
.

. General
Health (GH)
(45 55 ). ,
Physical Functioning (PF),
,
, ,

184 | III
, 2,3
,
(35 80 ).
Bodily Pain (BP)

,
, (41
84 ).

Role-Emotional (RE),
,
(67 ).

Vitality (VT) 45
85 ,
Mental
Health (MH), Social Functioning (SF) (45 56
).
. ,
,

,
.

,

..
[email protected]
, ,
,

() (): .. ..
THE STUDY OF MEDICAL PROVIDING FOR THE CITIZENS WITH THE
RIGHT TO SET SOCIAL SERVICES
Mikhaylova Y.
People's Friendship University of Russia, Russia, Moscow
The
Faculty of Medcine, Department of organization and economics of
pharmacy
Scientific Adviser(s): Dr. Kosova I.V.
Keywords: Medical providing, privileged citizens, free drugs,
prescriptions, financing
: , ,
,
Abstract: Study of medical providing for privileged citizens since 2001
and appreciating the consequences for this system after being reformed
in 2005.
:
()
2005 .
:

( - ),


;
,
.
:
2006 2010 ; 62


2001 2009
,
.
: ,

2005-2010 . 2005 14,8
, 2009 5,5 (37,16%
)
. 2006

19 972 832 . 3
13 323 093 (66,7%
). ,

.
,

,
.

,
. 2001
9,0 . , 2009
120,5 . ( 1338,88%).
. 2005

5 . .
2005 ,
.

() 2009 .

845 285 (46,77%) 280 612
(15,52%).
341 (0,02%).
,
, .
.
3,04% ,
3,61% ,
3,27% 2,76% .
(
) (2290,75)
(1555,95).
(321,20)
(341). 990,96
.
633,52 . , (11)

( 1198,96 ,
1151,35 ). 6
, (
489,21 , 493,97 ). 2

.



.
:
,
.
, ,
,
,
.

.., ..
[email protected]
, ,
,

() (): .. , .., ..
...
THE EFFECT OF AGING ON THE SPECTRAL CHARACTERISTICS OF
SUBSTANCES IN THE NEAR INFRARED SPECTROSCOPY (NIR)
Morozova M.A., Rugundiza R.D.
Peoples' Friendship University of Russia, Russia, Moscow
The Faculty of Medicine, Department of Pharmaceutical and
Toxicological Chemistry

 . , , , 2011 | 185
Scientific Adviser(s): Ph.D. Elizarova T. E., Ph.D. in chemistry Pleteneva
T.V.
Keywords: spectral characteristics of drugs, near infrared spectroscopy,
pharmacological classes, statistical separation, spectra.
:
, ,
, , .
Abstract: We evaluated the effect of aging on the spectral characteristics
of drugs in the near infrared. We investigated the substance of different
pharmacological classes: Piracetam (5 series), chloramphenicol (4
series), aspirin (4 series), hydrocortisone acetate (4series), rutin (2
series), Bromhexine (2 series). Statistical separation of NIR spectra of a
drug suggests the possibility of detection of qualitative and quantitative
differences in storage of samples in normal conditions.
:

.
:
: (5 ), (4
), (4 ), (4 ), (2
), (2 ). Nicolet ANTARIS, Thermo Scientific, .

.
9 -
.

-.
: -
,
.

.
2- -
.

.

(3 ),
.

,
.
.
: -


.

..
[email protected]
, ,
,

() (): ... ..
ESTIMATION OF INFORMATION SERVICES IN PHARMACEUTICAL
ORGANIZATIONS
Murzich T.V.
Peoples' Friendship University of Russia, Russia, Moscow
The
Faculty of Medicine, Department of organization and economics of
pharmacy
Scientific Adviser(s): Ph. D. Gribkova H.I
Keywords: Information services, pharmaceutical employees,
pharmaceutical organizations of Moscow, opinion poll

: ,
, ,

Abstract:The purpose of this study is to research information services in

pharmaceutical organizations of Moscow. There was conducted the
opinion poll among pharmacists. It shows that in most of cases
information services realized by base medicine information, information
about available assortment and price at drugstore. The information
sources for customer are pharmacists, news-papers and Internet.

.
: , , ,
;

.
: ,
, :
56%
35%
6%
3%
,

.
-
.
:
- (,
91500.05.00072003)
-
-
- (
-, 1+1 )
- .

: ,
, , ,
, - .

.

:
35%
33%
- 22%
, 9%
1%
,

,
:
53%
, - 27%
- 20%
, ,

(97% ).

,
:
- - 48%
- - 31%
21%
,


. ,
, :
- 36%
1+1 33%
31%

186 | III

70% .

.
,
.

:
32%
30%
20%
18%
: ,

, ,
.
, .

. ,

..
[email protected]
, ,
,

() (): ... ..
TYPES OF INSURANCE COVERAGE APPLIED TO CLINICAL DRUG TRIALS
Murtazin M.D.
Peoples' Friendship University of Russia, Russia, Moscow
The Faculty of Medicine, Department of Management and Economics of
Pharmacy PFUR
Scientific Adviser(s): Ph.D. Kurashov M.M.
Keywords: insurance, coverage, clinical trials, development, professional
liability, malpractice, insurance company
: , , ,
, ,

Abstract: Insurance procedures involved in clinical drug trials'
management are extremely complex, therefore it is not always clear
which of the many kinds should be selected for each case.
This overview presents the most vital types of insurance. They have to
be considered for the trials, because the fact of their use demonstrates
preparedness of the research company and its commitment to the
matter, which undoubtedly makes the results of the trials more reliable
and valuable.
()
,
.

.


. , ,
.
.
( )
, - - .
,
.

,
.
, ,

, - .
,
.

,
,
,
, .

.
,
,

.
.
, , .. ,
,
,
. , ,

.

, ,
,

, ,
.
, , ,
, ,
.
: ,

.
.

.
,
, .
965 23.10.2009.

2020 ,
( ,
),
, , ,
.

(OFF-LABEL)


.., ..
[email protected]
, ,
,

() (): ..., .

"FREQUENCY OF OFF-LABEL PRESCRIBING IN RUSSIAN FEDERATION:

ANALYSIS OF ADRS DATA BASE AIS ""ROSZDRAVNADZOR"""
Pereverzev A.P., Astakhova A.V.
People's Friendship University of Russia, Russia, Moscow
The
Faculty of Medicine, Department of pharmacology and clinical
pharmacology
Scientific Adviser(s): Ph.D. Astakhova A.V.
Keywords: pharmacoepidemiology, off - label prescribing
: ,

Abstract: Off-label use of prescription drugs is widespread. Off-label use
of a drug is defined as a prescription for an indication different from the

 . , , , 2011 | 187
indication, age, dose, rout of administration etc... stated in the package
leaflet. We coducted the analysis of ADRs data base AIS
""Roszdravnadzor"" to evaluate the freuency of off-label prescribing in
Russian Federation for the first quarter of the year 2009. The study
enrolled 861 reports of ADRs, associated with drug therapy. Overall
about 18% of all prescriptions were off-label. The results show that the
problem of off-label use of medicines and controlling adverse effects of
such therapy is up-to-date a relevan
:
()
(""off-label"").
,
, ,
, .
, ,
(2).

,
, .

""offlabel"" .


()
2009 .

861
155 (18%)
.
""off-label"" ,
,
,
(1). ,
""off-label""
:
(33 , 21%),
(29 , 19%),

(29 , 19%).
- 177 63
(35,6%), .

, off-label

,
.
:
1.Radley DC, Finkelstein SN, Safford RS. Off-label prescribing among
office-based physicians. Arch Intern Med. 2006;166:1021-6 [PMID:
16682577]
2.Stafford RS. Regulating off-label drug use--rethinking the role of the
FDA. N Engl J Med. 2008 Apr 3;358(14):1427-9.

.., .., ..
[email protected]
, ,
() (): ,

..
ZOLEDRONIC ACID AND RISK OF RENAL IMPAIRMENt
Serikova M.A., Astakhova A.V.,Kazakov A.S.
People's Frienship University of Russia, Russia, Moscow
The Faculty of medicine, department of pharmacology
Scientific Adviser(s): Prof. Lepakhin V.K.

Keywords: Zoledronic acid, renal failure, adverse reactions

: , ,

Abstract:Zoledronic acid is associated with reports of renal impairment
and renal failure, especially in patients with pre-existing renal
dysfunction or other risk factors. The majority of adverse reactions were
generally occured in patients with pre-existing renal dysfunction,
advanced age, use of concomitant nephrotoxic drugs or diuretic therapy,
or dehydration.Healthcare professionals are advised to take precautions
to minimize the risk of renal adverse reactions with zoledronic acid.

, -,
.
200 , 2,5
.

(, ,
, , , ,
),
.

()
, ,
( 3 )
.
,
, , ,
,
.

, ,
,
,
,
.

, , ,

,
.


. , (Vigibase)
972
.

, , , ,
, , .
2
,
,
:
1. 60

,
, ,
190/100 .. 40
.
,
.
,
.
, ,

.
2. 5

,
.
-
.
,
,

188 | III

, :
/
,
,
,
,

15 ,
,
.

..
[email protected]

,
() (): , ... ..
CERVICAL CANCER AND HIS PREVENTION
Simanovich A.G.
The Novgorod State University of a name of Jaroslav Wise, Russia, Great
Novgorod
The Faculty of Pharmaceutical, Department of pharmacy
Scientific Adviser(s): Prof., Dr. Sci.(biol.) Okonenko L.B.
Keywords: Cervical cancer, prevalence, prevention, vaccination, Gardasil,
Cervarix
: , ,
, , ,
Abstract:There are records on a level of a cervical cancer deseases in
Great Novgorod and region presented in theses. Detectability of a
cervical cancer in Novgorod region and Great Novgorod exceeds this
index for Russia. Therefore the only method to prevent it is the
vaccination against a cervical cancer. Obtained data give us hope that
vaccines Gardasil and Cervarix will be included in Russian National
immunizations schedule in the immediate future.

.
:
- ()
500000 (79 % );
- 200000
.
2- ( )
,
- 1- , - 3- ,
.
2008 .: 12-16 100 . ;
13 419 .


40 .
29 :
1993 2002 . 150
( 2,1%).
,

.
-
.
,
,

, ,

, ,
.
-
- ,

.

: 100 .
2006
101,5 ; 2007- 69,3; 2008- 51,5; 2009- 74,5;
2010- 61,4.
.
. 2006
142859 , 2010- 164443.
,
.


-.
-
.
,

: .

. 100%
,
6,11,16 18 (), ..
, .
,
, . ,


."

IN VIVO


..
[email protected]
, ,

() (): ... - .., ...
. ..
THE PHOTODYNAMIC ACTIVITY OF NOVEL SYNTHETIC
BACTERIOCHLORIN DERIVATIVE IN VIVO
Shishova E.Y.
Peoples' Friendship University of Russia, Russia, Moscow
Department of pharmaceutical and toxicological chemistry
Scientific Adviser(s): Ph.D. Ivanova-Radkevich V.I.
Keywords: Photodynamic therapy (PDT), Bacteriochlorin, Cancer,
Photosensitizer, experimental sarcoma S-37
: (),
, , S-37
Abstract: This report describes testing of a new synthetic bacteriochlorin
for PDT activity. The compound has PDT activity and low dark toxicity.
This bacteriochlorin is promising agent for further study.
()

.
()
.

,
,
,
,
*1,2+.
,
,
*3,4+.

(PhOBc) in vivo.

 . , , , 2011 | 189
.
PhOBc, "" """"
.. .
- 20-22
S-37.
.

4% 268 ( 268 -
.).
PhOBc 4% 268 /
6- 2 24
5,5 / 2,5 /.
.
740
( 30 ).
80-90 /2, 120 /2.
20

, - .

() () 20-
.
.
5,5 / .

. 24
PhOBc 5,5 /
10- 15-
( 72-54%), 20 % 20-
. 2
5,5 /
10 ( 59%),
10 % 20- . PhOBc
2,5 /
S-37
2 24 ( < 50 %).
. , ,


in vivo.

1.Liou GY, Storz P. Reactive oxygen species in cancer//Free Radical

Research. 2010. - Vol. 44, Issue 5. - P. 479-496.
2.Buhong L., Huiyun L., Defu C. et al. Detection system for singlet
oxygen luminescence in photodynamic therapy//Chinese Optics Letters
2010.- Vol.08 , Issue 01.- P 86-88.
3.Dabrowski JM; Arnaut LG; Pereira MM et al. New halogenated watersoluble chlorin and bacteriochlorin as photostable PDT sensitizers:
synthesis, spectroscopy, photophysics, and in vitro photosensitizing
efficacy//ChemMedChem. 2010. - Vol. 5(10). - P. 1770-80.
4.Huang YY; Mroz P; Zhiyentayev T et al. In vitro photodynamic therapy
and quantitative structure-activity relationship studies with stable
synthetic near-infrared-absorbing bacteriochlorin photosensitizers// J
Med Chem. 2010. - Vol. 53(10). - P. 4018-27.


[
,


.]

[,

]
[SOCIAL HEALTH AND HYGIENE]

 . , , , 2011 | 191
-

..
[email protected]
.. ,
,
1,

() (): , ...,
. ..
MEDICAL AND SOCIAL FACTORS OF PROBLEM OF DIABETES MELLITUS
IN UKRAINE AND IN THE EUROPEAN REGIO
Antonyuk E.Ya.
National O.Bogomolets Medical University, Ukraine, Kiev
The Faculty of Medicine 1, Department of social medicine and health
organization
Scientific Adviser(s): Doctor of medical sciences, professor Moskalenko
V.F.
Keywords: Diabetes mellitus, complications of diabetes mellitus, date
base SINADIAB
: ,
,
Abstract: The article is dedicated to the problem of early diagnostic of
diabetes and its complications. The aim of investigation was to learn
spreading complications above patients with diabetes mellitus in Ukraine
and in the European region. Late diagnostic required great cost on
treatment. Unfortunately, there is the high rate of mortality in case of
renal insufficiency in our contry compared that one in Europe. "
: . ,
.
, ,
, ,
.


, .
:
,
,
, .
.

- ,
,
,
,

.
, 2007
20
79 246 . , 2025
380 .
7 .
3 . ,
, 10
1 .
2006 ,
, ,
-
.
, 2 ,
. 2000
131,6 100. ,
2008 248,4 ( 1 13,1 28,5
100 . ; 2 118,5
219,8 100 .).

1 . 230 . .
,
( 2,6%) ,
,
.

10 (38,1-40,3 2,2-2,8%
).
(. ,
), ..,
,
, , ,
.

, ,
.
3%
, 30%.
.

,
.
. "

.
.., .., .., ..
[email protected]
-
, , ,
.
() (): ... .., ..., .
..
VALUE OF THE MEDICAL DOCUMENTATION IN CIVIL PROCESS.
Barinov E.H., Kosukhina O. I., Romodanovsky P.., Cherkalina ..
The Moscow State Mediko-stomatologic University, Russia, Moscow
Medical faculty, Chair of forensic medicine and the medical right.
Scientific Adviser(s): Ph.D. Barinov E.H., Ph.D. prof. Romodanovsky P.O.
Keywords: medical examination, medical documents, defects of
rendering of medical aid.
: - ,
, .
Abstract: In article the data about value of the medical documentation is
cited by manufacture of commission forensic medical examinations on
civil cases, errors are noted at filling of medical documents.
:
-

.
: ,

. -

.
,

. -
. : ,
,
, ,
, , ..
-, , ,
.

, ,

,
.

,
, ,
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.
, - .

192 | III
,
:
1. .
2. .
3. .
4.
.
5.
.
6.
.
7. ,
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8. .
9. .
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2) ;
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.
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-
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,
.

.
,
,
:
1)

;
2) ( /
);
3)

;
4) ().

. ,
.
,
, ,
."

..
[email protected]
, ,
, ,

: ... . ..
INFORMATION SUPPORT IN QUALITY OF CARE AND MEDICAL HELP
Bershadskaya M.B.
Peoples Friendship University of Russia, Russia, Moscow
The Faculty of Medicine, Departament Public Health, Health Care and
Hygiene
Scientific Adviser: Ph.D. Breusov A.V.
Keywords: provision of information, organization of care, quality of care,
quality of nursing care, standard
: , ,
, ,

Abstract: Nursing care is an important branch of medicine. Primary role

in providing care and its quality is at the middle and junior medical
staff.Physicians underestimate the role of staff and patient care in quality
of care.Without creating an information management system for middle
and junior medical staff can not get high-quality and continuous system
of education, patient care, medical help.
:
.
,
.
,
. ,
-
.
:
16 . , ,
, .
10375 (98,6 %), 137 (1,30 %), 10512,
267, 21 .
,
954 .
(9,07 %),
4781 . (45,48 %),
4777 . (45,44 %).
49 . (0,46 % 35,76 %
)
88 . (0,83 % 64,23 %
) .

.
182 , 34 .
, 118 . ,
61 .
, 18 . (,
) , 11 . , 12 .
. 13
, 36 . , .
,
.

73 88 %, 41 78 %
(

).

( ),
. 256
, .. , 213
,
,
.

, , ,
, ,
, . 248
,

,
.

,

, , , ,
.


.

- ,


,

 . , , , 2011 | 193
,
-
,

, ,
.

..
[email protected]
, ,
, ,

() (): ..
EVALUATION OF MEDICAL INFORMATION SUPPORT STAFF QUALITY OF
EDUCATION AND HEALTH CARE
Bershadskaya M.B.
Peoples Friendshep University of Russia, Russia, Moscow
The Faculty of Medicine, Departament of Public Health, Health and
Hygien
Scientific Adviser(s): Ph.D. Breusov A.V.
Keywords: quality of medical care, information management,
information sources, medical education
: ,
, ,
Abstract: The average medical personnel are the most numerous
category of medical workers on which quality of medical aid in many
respects depends. Quality of medical aid cannot correspond to due level
without quality of a secondary education of medical workers. In our
country there is no unified system of information for management
specialists with secondary medical education at undergraduate and
postgraduate level, without which it is impossible to achieve quality
education and health care.
:
()
()
(). ,
- ,
,
, , .

- : , ,
, , .,

, ,
, ,
.
: 1352
, 104 , 578 10
(), 108
, 562 .
: 75,77 %
(438 .) , 85,18 % (92 .) , 73,30 % (412
.) .
:
20,19 % (21 .) , 12,45 % (72 .) (
,
, .. ), 94,44 % (102
.) , 83,98 % (562 .) .
,
:
74,03 % (77 .) , 72,14 % (417 .) , 94,44 % (102
.) , 84,34 % (474 .) .
, , ,
.
: 37,88 % (219 .)
, 94,44 % (102 .) , 84,87 % (477 .)
. .

,
, , ,
.
.

( 30
).
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.

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[email protected]

, ,
,

() (): ..
RESEARC OF MAINLY STATE SYSTEM OF PUBLIC HEALTH SERVICES
Borodina S.A.
GOU VPO the Russian state medical university Roszdrava, Russia,
Moscow
Medical faculty, Chair of public health and public health services Senior
lecturer
Scientific Adviser(s): Tolchyonova E.A.
Keywords: The state system, expenses, expenses, financing, life
expectancy
: , , ,
,
Abstract: to reveal advantages and lacks of the state system of public
health services of Italy. By calculations of experts the general expenses
on public health services of Italy can rise. Regional financing occurs from
the regional tax to the businessman, a share of the individual surtax, the
certain sum excises on gasoline, from the tax to the engine of a vehicle ,
etc. the generality principle is put In a basis of financing of public health

194 | III
services between generations with introduction of a general, free
covering. Perfection of system of public health services of the country by
elimination of its revealed lacks is necessary.

trachea, appendages and pipes, a stomach. 1/3 patients are in IV stage.

Perfection in the medical aid organization oncological patients is
required.

.
: .

:
, , .

.

62.
3 (2007-2009)

:
2009. 1818 .
2,4%(2,4 % ).
,
, 6,3% 2010. 11% 2050.

77%, 23%.
( 46% )
, 4,3%. 2001
:
(IRAP - Imposta
Regionale sulle Attivit Produttive (regional business tax)): 90%
IRAP;
(IRPEF Imposta sui Redditi delle Persone Fisiche (personal income tax)),
0,9%,
IRPEF 0,9% 1,4%;
( 0,13 ) ;
0,026
,
,
.
,

,
(
).
40% , ,

, , .

:
78,4, 84.
:

.

..
[email protected]

, ,
,

: ..
THE ORGANIZATIONS OF MEDICAL AID AND A STATE OF HEALTH
ONCOLOGICAL PATIENS AFTER CHEMOTHERAPY
Bursky S.S.
GOU VPO the Russian state medical university Rozdrava, Russia, Moscow
Medical faculty, Chair of public health and public health services Senior
lecturer
Tolchyonova E.A.
Keywords: Oncology, chemotherapy, the medical aid organization,
lethality
: , ,
,
Abstract: The oncology concerns to socially-significant in structure of
death rate, physical inability. The purpose research: improve the medical
aid organization oncological patients. Structure of localization of tumoral
process: colorectal a cancer, a cancer of a mammary gland, a lung and a

:
: 1 - (2009
. 21,9%; 2008 . 16,1%; 2007 . 14,3%), 2-
(2009 . 15,3%; 2008 . 17,1; 2007 . 17,2%), 3 -
(2009 . 12,9%; 2008 . 11,6%; 2007 . 13,9%), 4 -
(2009 . 10,8%; 2008 . 12,3%; 2007 . 11,9%), 5 (2009 . 10,4%; 2008 . 12,0%; 2007 . 11,2%). 1/3
IV
(2007 . 35,4%; 2008 . 32,6%; 2009 . 31,9%), 1/6 III
(2007 . 17,4%; 2008 . 16,1%; 2009 . 16,5%), II
2007 . 4,7% , 2008 . 4,8%, 2009 . 4,8%; I -
2007 . 2,2%, 2008 . 1,2%, 2009 . 1,2%.
2009 .
92,9 % , 2008 . 91,5%, 2007. 92,1%; -
2009 . 3,1%, 2008 . 0,3%; 2009 .
2,6%; 2008 . 2,6%, 2007 . 2,0%; + -
2009 . 1,6%, 2008. 1,6%, 2007 . 1,9%.
0,74% 2007 . 1,1% 2009 .
- ,
, ,
, .
,
.

-

..
[email protected]
- .
..
- ,

: ... ..
MEDICAL KNOWLEDGE AND MEDICO-SOCIAL ACTIVITY OF THE
POPULATION OF A MEGACITY
Zelionko A.V.
Saint-Petersburg state medical academy named after I.I. Mechnikov
The Medical-preventive Faculty, Department of public health and public
health service
Scientific Adviser: Ph.D. Grigorieva N.O.
Keywords: Medical knowledge, healthy way of life, quality of life, risk
factors
: ,
, ,
Abstract: Medical knowledge is one of important conditions of saving of
human health. This research was carried out by a method of questioning
with the help of specially developed questionnaire. As a result of
research the population has been divided into 3 groups on level of
medical knowledge (high, average, low). It has been established that
high level of medical knowledge provides formation of healthy behavior
that promotes decrease in incidence of widespread diseases caused by
various risk factors.
: ()

.

 . , , , 2011 | 195

,
.
,
- ,
.
: 360 ,
. -.
-
. ,
, , , .
3 ,
.
(66,0%),
(73,6%)
29 .
,
(50,0%),
31,0%, 19,0% . ,
, (53,0%),
(63,0% 74,8%).
59,4% ,
38,8%.
(61,7%),
(66,4% 60,1%).

(62,2%).
(64,7%)
, 23,3%
12% .
,
, 82,8%, (51,7%)
.
92,0% . , ,
(
72,3% 2-3 4 ), ,
( 65% 1
). ( 70% )
.
,
: 55,8%
, 1-2 (83%),
(68,6%).
(73,4%)
(64,8%) .
, ,

.
, (
)

,
.

-
-
.
.., ..
[email protected]
, ,
, ,
.
: ... ..
CLINICAL-EXPERT COMISION IN DERMATOVENERELOGY AND SOCIALHYGENIC ASPECTS OF PATIENTS OF DERMATOVENEREOLOGICAL CLINIC
Kaverina E.V., Malyarenko E.N.
Peoples' Friendship University of Russia, Russia, Moscow
The Faculty of Medicine, Department of public health and hygiene
Scientific Adviser: Ph. D. Kicha D.I.
Keywords: Clinical-expert comission, dermatovenereology, quality of life

: - , -
, ,
Abstract: One of the most important problems of public health is
improvement of quality of medical service. There are a lot of chronic
deseases in dermatovenerology, which change patient's quality of life
and lead to social desadaptation. So clinical-expert reseach in
dermatovenerology should be improved.
:
, ,
,

.
- -

-
,
,

.
,
2009 ,
II

- , 2010,
.247-248.
, .
:
:
- -
-
- 5,
1-31 .
- 233 ,
5

233
5 55 (57%).
,
,
(L 40-45) 32%, (L 20-30) 29%.
2 :
(57%) .
, -
, 42%.
233 39% (1
- 2%, 2 - 32%, 3 - 5%). ,
.
,
(66%),

28%.
(65%),
(69%) 31-55 (31%),
18%, .
67% ( 2 - 53%)
(62%)
, 55 62%, 31-55 42%
16-30 14. 90%
( 1 0 , 2 - 76%, 3 - 14%),
.
, 2
(29% )
16% 31%.
3%,
,
.
55 (69%)
:
(L 40-45) 54%, (L 10-14) 12%,
(L 20-30) 14%,
(L 80-99) 18%

, (L60-75),
, .. , .

196 | III
, ..
.
(60%).
55
(69%).
53% (1 - 3%, 2 - 43%, 3
- 7%), .
5 10
(58%), 42% .

: 50 74%.
(74%).
.
-
,

.
,

.
-
,
."

-
..
[email protected]

, ,
,

: ..
TECHNIQUES OF IMPROVEMENT OF DIAGNOSTICS OF DISEASES OF A
GASTROENTERIC PATH
Kuprijanova V.V.
GOU VPO the Russian state medical university Roszdrava, Russia,
Moscow
Medical faculty, Chair of public health and public health services
Scientific Adviser: Ph.D Tolchyonova E.A.
Keywords: Pathology of a gastroenteric path, age structure, radiological
inspection, stomach ulcer of a stomach and the gut 12-item
: - ,
, ,
12-.
Abstract: to improve diagnostics of diseases of a gastroenteric path. In
structure diseases of a gastroenteric path the first place the stomach
stomach ulcer occupies, the second stomach ulcer of the 12-item of a
gut, the third chronic inflammation of the 12-item of a gut and
stomach. In the general age structure of stomach ulcer of a stomach on
the first place of the person of 60-69 years. The age structure of men
and the women, suffering stomach stomach ulcer doesn't differ from the
general age structure. Radiological inspection has great value in
diagnostics of diseases of a gastroenteric path.
:

- .
: : 405 ,
- .
:
-
.

,
. -

,
,
, ,

.

.
,
.
: -
, ,
30,2% (57,4% , 42,6% ), 12-.
25,9% (70,4%-, 29,5%-),
12% ( 59,1% , 40,8% ),
9,6% (46.1% , 53,8% ),
7,1% (41,3% , 58,6% ).

- 6,1%,
3,4%, 2,9%,
2,4%.
:
.

- .

.., .., ..
[email protected]

.. , ,
,

: ... ..
AWARENESS OF MOSCOW REGION HEALTHCARE PRACTITIONERS OF
THE AMBULANCE SERVICES REFORM
Leontev A.V., Lomakina E.V., Soloveva S.E.
I.M. Sechenov First Moscow State Medical University, Russia, Moscow
The Faculty f dicine, Department of public health
Scientific Adviser: Ph.D. Sitnikova O.Y.
Keywords:Reform,ambulance
: ,
Abstract: The main aim of this study is the analysis of healthcare
practitioners assessment ambulance services reform.
: ,

, 3

.
.
. ,
2020 ,

.


.
: ,


.
: 1- 52
. 2- 26 -
. 98,1%

. ,
. 23,5
., 51 ; ,

 . , , , 2011 | 197

(
.
, ).

,
,
, , -
.

1- ,
(83,5%) 30-40 ,
(16,5%) 31-35 .

2- - 56,9 %
46-50 , 43,1% 36-40 .

.
,
. 1-
, ,
, . 1-
,
,
, 28,5%
1 . ,
, ,
.
,
.
1- 82,6%
17,4% . 2-
57,9 % 42,1% .
.
1- (6-10
1-3 ),
2- ( 11-15
5 .
1-
,
,
.,
.
. 43,5 %

. ,

.
2- (73,7%)

, 1- (65,2%).
(13%) 1- ,
,
.
2- (53 %),
1- (35%).
1- 2-
(95,6%
100 % ).

(61% 1- , 42,1%
2- ),

.

:
1.
,
,
( ) .
2.
(

).
3.
-.
4.

.

..
[email protected]
, ,

- ,

: ... ..
THE FEATURES OF THE EPIDMIC PROCESS OF CHRONIC PARENTERAL
VIRUS HEPATITIS B AND C IN REGIONS WITH A HIGH PROPORTION OF
RURAL POPULATION FOR EXAMPLE LIKE IN THE ALTAI TERRITORY
Pashkov A.P.
The Altay State Medical University, Russia, Barnaul
The Faculty of preventive medicine, The Department of Public Health
and Health Care
Scientific Adviser: Ph.D. Kolyado V.B.
Keywords: chronic virus hepatitis B and C, epidemic process, regions with
a high proportion of rural population, liver diseases.
: ,
,
,
Abstract: The aim of the work is the determination of the epidemic
process features of chronic hepatitis B and C (HGB and HGC) in the
region with a high proportion of rural population. The incidence of HGB
and HGC in the region tends to be growth, and results of the study we
suggest that there are problems with the diagnosis of liver diseases
including HGB and HGC in the rural areas. The high share of the rural
population and the problems of medical care organization in areas with
low density of population cause the peculiarities of epidemiological
process in the region.
:
, 350 .
350 .
. 1,5 .
, ,
() ().
()
(), 3 2 .
. 80 %
, , ,
()
.

( )
.
:
1.
,

;
2.
;
3.
.
:
,
-

198 | III
.
Excel 2007 Statistica 7.0.
t-
.
.
1999-2009 . 1,6 7,5 2,1 45,5
100 . .
, 2007
10 2007. 280

(2007 2011 ),

.

-

46,2 2007 36 100
2011 ( 22%).
,
, (:
11,7+0,40/0000 5,9+0,30/0000, <0,01; : 55,9+0,90/0000
16,8+0,50/0000, <0,01).

(r=0,7; p<0,05), ,

(22,2+0,60/0000) (21,7+0,60/0000), ,
(p>0,05).

(r=-0,1; p<0,05) (r=-0,01; p<0,05).
(r=0,7; p<0,05) .
,

.
:
1. ,
5
.
,
.

. ,
,
;
2.
,

(2007 2011 .);
3.
.
,

.

( )
..
[email protected]
, ,
, ,

: ... ..
WORK SECURITY STATUS ON A WORKPLACE(SURGICAL BRANCH)
Ulkina A.A.
Peoples' Friendship University of Russia, Russia, Moscow
The Faculty of Medicine, Department of Public health, public health
services and hygiene
Scientific Adviser: Ph.D. Tadjieva A.V.
Keywords: The work organization, safety of employees of surgical branch
: ,

Abstract: According to Order of Minzdravsotsrazvitija of Russia from

8/31/2007 N 569, the order of carrying out of certification of workplaces
on the working conditions, including a hygienic estimation of existing
conditions and character of work, an estimation of injury prevention of
workplaces, the account of security of workers by means of individual
defense and fakti-cheskogo conditions of working conditions on
workplaces is established.
Results of certification of workplaces on working conditions are used with a view of:
Planning and carrying out of financing of actions for improvement of
conditions and a labor safety in the organizations according to operating
standard legal documents;
Control of a condition of working conditions on workplaces and
correctness of maintenance of workers the certificated means of
individual and collective protection;
Professional risk estimations, control and management of professional
risk;
Acceptances of measures on appropriate sanitary-household and
preventive maintenance of workers of the organization;
Inclusion in the labor contract of the characteristic of working
conditions;
Acquaintance working with working conditions on workplaces;
Applications of the measures of responsibility provided by the
legislation to the persons guilty of infringements of the legislation on a
labor safety.
:

,
-.
-,

-
.

31.08.2007 N 569,
,
,
,
-
.
:

-

;

-
- ;
,
- ;
-
- ;

;

;

-

.
:
-
.

,
,

,
. -

- .

, - .
: , ,
-
-,
,
- .

 . , , , 2011 | 199
,
- ,
- ,
.


, , .
,

,

:
,
.
.., ..
[email protected]
, ,

,
() ():... ..
THE MAGNESIUM DEFICIENCY IN STUDENTS: FUNCTIONAL
IMPAIRMENT, THE IMPACT ON THE EDUCATIONAL PROCESS AND
POSSIBLE WAYS OF CORRECTION.
Dubrovina I.N., Polyakov P.P.
Kuban State Medical Univercity, Russia, Krasnodar
The Faculty of Medicine, Department of faculty therapy
Scientific Adviser(s):Ph.D. Yeliseyeva
Keywords: deficiency of magnesium, magnesium, students, educational
process, UNESCO, questionnaire
: , , ,
, ,
Abstract: 4th year students during exams, and then in the middle of the
semester were invited to anonymously answer the UNESCO
questionnaire by magnesium deficiency. Its identified some of the most
frequent and severe symptoms, magnesium deficiency was observed in
one third of the respondents. Magnesium deficiency causes significant
functional decline, and we think that its correction will to some extent
improve the performance and viability of the knowledge gained.
,

.
, , ,
, ,
, ,

,
,
.

.
/ II
,
, .


(PCU ): 34 ,
, ,
.
3 2 ,
(,
, ) ,

,
,

.

2 . 1- 4

34 . 2-
( 5 )
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)
. 1- 163 , 2- 139.
:
,
.

: fast food
( ) 79,8% 62,6%
( 4 5 ) 16,0% 28,8% .
71,7% 74,8% . (
) (91,4% 4
90,6% - 5 ),
( 30,7% 38,8%).
: 79,7% 89,2% (
20,2% 17,3% ).
80,4% (17,2% )
92,1% (19,4%); (64,4% 70,5%);
(79,8% 75,5% 1 2
).
, 58,3% 60,4%,
5,5% 7,2% .
: 50,3% 54,6% (4
) 58,3% 38,8% (5 ) .
- 42,9% 42,3% 4
16,5% 38,9% 5 .
,
,

-
.
, ,



.

-

.
.., .. , ..
[email protected]
-

() ():, ...
., ... , .
INVOLVEMENT OF FORENSIC EXPERTS IN CIVIL AND CRIMINAL TRIAL THE FIRST STEP TOWARDS CONFLICT RESOLUTION IN COURT.
P.O.Romodanovskiy, I.L. Balashova, E.Kh.Barinov
Moscow State Medical-stomatological University
The Faculty of Medicine, Department of Judicial medicine and medical
right
Scientific Adviser(s):professor, d.m.n. Romodanovskiy P.O, k.m.n.
associate professor, Barinov E.Kh
Keywords: criminal procedure, bringing in of experts, tasks and
conclusions of judicial medicine
: , ,

Abstract: In article the data about value of medico-legal examinations
within the framework of civil and criminal court. The questions of the
goal setting are considered, tasks and conclusions, are put before
forensic experts to solve controversial issues of civil procedure.

200 | III
: ,
-


, .
: , -

:
, , , ,
-
.
: ,
, -
.

,
,
, , ..

..
[email protected]
, ,

-,

() ():... . .
ESTIMATION OF FEATURES OF EPIDEMIC PROCESS OF DISEASE OF THE
MENINGOCOCCAL INFECTION CITY AND AGRICULTURAL POPULATION
OF ALTAY TERRITORY
Smirnov s.p.
"The state educational institution
The higher vocational training
The Altay state medical university Federal agency on public health
services and social development , Russia, Barnaul"
Mediko-preventive, Chair of public health and public health services
Scientific Adviser(s):k.m.n. Smirnova K. S.
Abstract: Has finished the Barnaul base medical college in 2005, on a
speciality Medical business, qualification - the medical assistant. An
honors degree. In 2008. Has arrived in SMU on mediko-preventive
faculty.
:

,
- , .
60 16
.

,


.
:

.
:
1.

2007-2010 .;
2.

2007-2010 .;
3.

2007-2010 .
4.
2002-2007 .
.

100.000 .
:
. 2007 2010
.
. 2010
1,6 100 . ,
1,5 2007 .
2007
2009 . 2 , 2009 2010
1,6 , 2007 2009
1,1 , 2009 2010 2,3 .

.

.
4
: , , ,
.
29 .
12 . 16 ,
3- . 3
. ,

.


.

2007 2010 .
0 14 .
:
1.

.
2.

.
3.
2007-2010 . 100 .
0 14 ,

1,03 ,
1,03 .
4.
,
4.

..
[email protected]
172 ,

() (): ..
EPIDEMIOLOGICAL SUBSTANTIATION OF THE ORGANIZATION OF THE
AIDS-CENTER IN THE CITY TERRITORY OF DIMITROVGRAD
Teplova E.G.
Regional government 172 Federal medical and biologic agencies of
Russia, Dimitrovgrad
Department of epidemiological supervision
Scientific Adviser(s):Teplova T.E.

 . , , , 2011 | 201
Keywords: AIDS-center, epidemiology, HIV-infection
: -, , -
Abstract: Various epidemiological data on a HIV-infection in the city of
Dimitrovgrad is processed. Necessity of approach of the medical and
preventive help is shown the population. Necessity of the organization
of the AIDS-center in the city territory of Dimitrovgrad is proved.
- ,
. 2009
35 ,
. 2009 58 448
- , 8%
, 2008 . 31.12.2009 529 828
- .


-.



172 .
172

(
, )
(

AmpliPrep,

Roche).

.
-
1997 . 01.01.2010
-
, 1185,2 100
746,9 100 .
(335,4 100 ).
- 01.01.2010
1517 - . 875 (683, 6
100 ), 57,7%.
- 386 (44,1%) 489 (55,9%).
- 15 29 28,3%,
.
:
452 (51,7 %),
386 (44,1 %), 19 (2,2%), 18 (2,0 %).
01.01.2010 - 186 .
123 , 2
, 1 , , 20 - 40
.

.
- 1,5
3 .
, 1/6 (166
- 16,7%) .

- ,
, -
, -
,
- ,
..
- :
1517
57,7% (875 )
.
,
,
,

,
,

,


.

..
[email protected]
, ,
, ,

() ():..., ..
SATISFACTION WITH QUALITY OF MEDICAL CARE IN POLYCLINIC OF
FAMILIES WITH PRIMARY SCHOOL AGED CHILDREN
Khudaibergenova M.V.
Peoples' Friendship University of Russia, Moscow
The Faculty of Medicine, Department of Public Health, Health Care and
Hygiene
Scientific Adviser(s):doctor of medical sciences, professor Kicha D.I.
Keywords: satisfaction, quality, medical care, family, children
: , ,
, ,
Abstract: The purpose of this study was to examine satisfaction with the
quality of medical care in the polyclinic of families with school aged
children. 45.8% of families not satisfactory assess the work of polyclinic.
Administration of polyclinic, taking managerial decisions can affect the
quality of services to the population - increase the activity of health
professionals working with chronically ill children and their parents and
control the flow of children.

,
, ,

: 648

118 . . :
-
,
,
.
.


. ,

54,2%
,
45,8% .
,
,
2 ,
(35,4% 18%
(p<0,001)). , ,

.
:
(48,1%), (19%),
(19%),

, (7,9%),
(4,8%). ,
,
.
,
(51,1%) -
,
. , 59,8 %

, 35,8%
4,4% .

202 | III
(40,4%),
37,1% ,

.
. 45,8%
.
: ,
, ,
, ,
.
, ,


, . ,
, ,

, , ,

.

.., ..
[email protected]
, ,

- ,

() ():... ..
THE HYGIENIC ASSESSMENT OF A FACTUAL NUTRITION OF CADETS
Shyrko D.I., Ushkov A.A.
Belarussian state medical university, Belarus, Minsk Military-medical
faculty, Chair military epidemiology and military hygiene
Scientific Adviser(s):Ph.D. Doroshevitch V. I
Keywords: cadets, factual
: ,
Abstract: Cadets nutrition is characterized by the abuse of
energycontent, excess consumption of fats and carbohydrates,
insufficient amount of proteins, vegetable lipids, pectins, calcium,
vitamins A and B2, which may be eliminated by decreasing
consumption of cereal products and potatoes, increasing amount of
dairy products, fish and juices, including polivitamins medicines




.

- ,
,
,

,

.

84

,
, , , ,
1, 2, .

,

3500 , 123 (
68 ), 117 (
35 ),
23 , 490 , -
74 , 20 , 900
, 1 1,5 , 2 1,8 , 23,0 , 90,0 , 1000
, 800 400 .

,

,
, ,
, , 2,
.

.
( = 15,50 (13,60 15,40) ),
(27,11 0,69 ), (12,470,32 )
,
(86,741,36 %)

.
( = 113,25 (101,66
115,12) ) ,
98,48 (88,40 100,10) .
( = 2,3 (2,10 5,30)
/) 2 ( = 2,00 (1,80 3,20) / )

, ( = 117,55 (98,80 127,6) /
), ( = 2,00 (1,80 3,20) / )
( = 27,10 (24,80 27,80) %)
.


, 29,0 % ,
11,5%, 1,6 % (0,52%),
4,2 % (0,87 %)
26,6 % (9,22 %),
0,7 % (1,74 %),
3,9 % (34,9%), 3 . (2 . 3 ),
2,1 % (6,96 %).
:
1.
, -
.
2.

, ,
, .

. .,

() (): ... .
HYGIENIC ASSESSMENT OF DRINKING WATER IN THE ASTRAKHAN
REGION
Kibeshov Ilya, Peoples Friendship University of Russia
Scientific Adviser(s): PhD Drozhzhina Natalia
: , ,
, , , , ,
.
Keywords: hygiene of
water, Astrakhan, environment, health, Volga,
water
treatment
plants, sewerage,
caries.
Abstract: in
the Astrakhan region there
are excess
of hygienic
standards for content in the drinking water such substances as
manganese,
fluorine, and there
is
a
disparity in microbiological indicators,
the
principal
reasons that regarded are the inconsistency of water treatment
plants, and soil pollution by solid waste.
- .
.

, . (
., ., . .).

, ,
.

 . , , , 2011 | 203
1998-2008 .

. - 1,2 5.
,
, : 2005
-0,104/, 2006 0,083 /3, 2007 0,062 /3
2008 0,03 /3. ,
- ,
(11,4 %)
68,4 %.
(, ) 2008-2009 .
,
.
,

.
,
.
: ,

; ;
,
.
.

,

, ,
, ,
.
2008 . 102,9 ,
611266,6 3


.
.
,
(Maryse F. Bouchard, Sbastien
Sauv, Benoit Barbeau, Melissa Legrand, Marie-ve Brodeur, Thrse
Bouffard, Elyse Limoges, David C. Bellinger, Donna Mergler. Intellectual
Impairment in School-Age Children Exposed to Manganese from
Drinking Water.)
.

.
2009 .

20072011
800 495 . ,

2009 .
3 %; 2008 .
3,3 %.

204 | III

INDEX

Adefela Fagbemi, 15
gnes Nemeskri, 119
Amit Tripathy, 71
Andrs Szuk, 119
Andrs Szura, 95
Andrea Debreczeni-Mr, 15
Asogva Innocent Kingsley, 15
Avany Albert Souren, 15, 16
Basharov M, 16
Bhooneswar S, 16
Bikov Andrs, 70
Borsaly Leila, 15
Bukosza E. N., 71
Csaba Kis Szntai, 172
Csaba Korom, 119
Cssza Gyrgyi, 70
C .., 17
Endre Gti, 119
Farkasdi Sndor, 106
Generalov I.M., 98
Goryainova K.E., 98
Gulcsi-Brdos P, 71
Gyrgy Kri, 172
Gyula Marton Kohl, 153
Horvth Ildik, 70
Ibrohimov Sh.I., 72
Ibrohimov Sherostan, 106
Ildik Horti, 119
Karlcai Kristf, 70
Kroly Nmeth, 119
Kiss R. G., 71
Klra Tr, 119
Klaudia Vivien Nagy, 70
Kornilova L.E., 72
Kovcs Dorottya, 70
Kughan Govinden, 15, 70
Lszl Kbori, 119
Lszl rfi, 172
Laura Flumbort, 95
Losonczy Gyrgy, 70
Marcsa B., 71
Mtys Kiss, 119
Mohammad Fiqry, 16
Nieszner E., 71
Omary Nassoro, 15
Oszlnszky Judit, 106
Pk Judit, 70
Petrova N, 15, 16
Prda I., 71
Prosvetov Roman, 106
Rubanes Mohan, 106
Sadikov I.H., 72
Shandor Farkashdi, 15
Smirnov E., 72
Sokov Petr, 106
Vignes Mohan, 106
Yakovlev M.V., 72
Yakovlev Michael, 106
Zoltn Horvth, 172
Zoltn Nemes, 172
Zsolt Ppai, 119
Zvezdilin E.L., 123
., 164
.., 178
..., 181
.., 119, 132
. ., 133
.., 74
, 133
.., 37

.., 169
.., 21
. ., 107
.., 126
.., 32
.., 37
. ., 75
. ., 56
.., 80
.., 102, 104
.., 59
. ., 180
.., 80
.., 181
., 34
.., 33, 35
., 18
.., 172
.., 191
.., 28
.., 128
.., 95
.., 74
.., 73
.., 52
.., 85, 157
., 37
.., 182
.., 145, 150
.., 186, 187
.., 85
.., 164
.., 173
.., 174, 175, 178,
179
.., 134
.., 108
.., 95
.., 191
. ., 88
.., 86
.., 38
.., 120
.., 114
.., 84
.., 164, 166
.., 38
.., 135
.., 192, 193
.., 182
.., 120
.., 89
.., 82, 153
.., 50
.., 135
.., 63
.., 74, 78
.., 135
.., 133
.., 144
.., 193
.., 19, 104
.., 99, 101, 105
.., 37
.., 19
.., 38, 51
.., 194
.., 95
.., 130, 136
.., 175

.., 147
.., 100
. ., 20
. ., 153
.., 126
.., 175
.., 39
.., 34
..,, 96
. ., 107
. ., 133
.., 97
.., 98
.., 121
.., 50
.., 156
.., 108
.., 158
.., 92
.., 50
.., 173
.., 42
..., 60
.., 63
.., 29
.., 121
.., 139, 140
.., 98
.., 41
.., 182
.., 61
. ., 107
., 40
.., 135
.., 154
.., 54, 121
.., 168
.., 40
.., 126
.., 100
.., 96
.., 174
.., 132
.., 41
.., 41
. ., 75
.., 122
.., 42
.., 109
.., 168
. ., 175
.., 41
.., 33
..,, 35
.., 20
.., 131
.., 169, 199
.., 63
.., 199
.., 103
.., 115
.., 116
.., 145, 150
. ., 137
., 17
.., 43
.., 138
.., 139
.., 123
., 19

.., 104
.., 178
.., 50
.., 178
.., 99, 101
.., 73
.., 24, 25
.., 159
.., 43
.., 129
.., 27
.., 123
.., 175, 182
.., 139, 140
.., 194
.., 134
. ., 75
.., 141
.., 160
.. , 199
.., 34
.., 34
.., 165
.., 52
.., 64
.., 53
.., 87
.., 180
.., 18
., 195
.., 187
.., 42
.., 100
..., 109
.., 65
.., 38
.., 110, 111
.., 105
.., 176
.., 135
C., 161
.., 21
.., 43
.., 52
. ., 202
., 51
.., 112
.., 119
.., 147
.., 43
.., 124
. ., 107
.., 33, 35
., 19
.., 168
.., 76
.., 160
., 114
.., 169
.., 101
.., 41
.., 36
.., 44
.., 87
.., 21
.., 100
.., 175
.., 141
.., 28
., 81

 . , , , 2011 | 205
.., 29
.., 124
. ., 22
.., 191
.., 142
.., 51
. ., 45
.., 76
.., 46
.., 77
., 24
.., 25
.., 175
.., 112, 141,
143
.., 50
.., 29
.., 101
.., 196
.., 47, 48
.., 19
.., 41
.., 65
.., 22
..., 60
.., 119
.., 133
.., 126
.., 103
..,, 196
.., 177
.., 49
.., 21
.., 50
.., 55
.., 196
.., 50
.., 125
.., 166
.., 17
.., 92
.., 155
.., 143
.., 178
.., 183
.., 195
.., 63
.., 86, 88
.., 85
.., 105
.., 38
..., 178, 181
.., 23
., 38, 51
.., 76
., 52
..,, 141
.., 52
.., 54
.., 122
.., 112
.., 42
.., 184
.., 82
.., 184
.., 42, 58, 59
.., 89
.., 126
..., 181
...., 178
.., 164, 166
.., 129
.., 30
.., 185
.., 186

.., 178
.., 30
.., 102
.., 124
.., 30
.., 113
.., 50
.., 23
.., 53
., 111
.., 38
.., 66
.., 38
., 95
.., 44
.., 114
.., 54
.., 80
.., 54
.., 50
.., 125
. ., 54
.., 89
. ., 86
.., 175
.., 102
.., 28
.., 119
.., 199
.., 159
.., 197
.., 186
.., 178
.., 82, 153
.., 83
.., 34
.., 55
.., 63
., 77
.., 103
.., 199
., 143
.., 164
.., 28
.., 114
.., 55
.., 100
. ., 90
.., 40
.., 27
.., 47, 48
. ., 72
.., 179
.., 41
.., 180
.., 191
.., 184
.., 24, 25
.., 91
.., 65
.., 52
.., 33, 35
.., 40
.., 90
. ., 86
., 32
.., 130,
136, 144
.., 126
,
161
.., 87
.., 29
.., 103
.., 56

.., 38
.., 95
.., 126
.., 56
.., 35
.., 91
.., 127
., 101
.., 105
.., 50, 57
.., 127
.., 25
.., 92
.., 187
.., 182
.., 188
.., 114
.., 110, 111
.., 74, 78
.., 102
.., 44
., 133
.., 200
. ., 86
.., 106
.., 196
.., 57
.., 147, 148, 149
.., 58
.., 140
.., 77
.., 50
.., 102, 104
.., 24, 25
.., 128
.., 100
.., 129
.., 173
.., 145, 150
., 24
.., 25
.., 78
.., 35
., 115
.., 50
.., 200
.., 180
.., 78
.., 84
.., 26
.., 146
.., 135
.., 115
.., 147
. ., 107
., 65
.., 131
- ..,
180
., 126
.., 47
.., 198
.., 28
.., 173
.., 202
., 107
.., 50
.., 42
.., 74, 78
.., 180
.., 29
.., 48
.., 26
.., 79
.P., 80

.., 26
. ., 107
.., 48
.., 139, 140
.., 58, 59
.., 42, 59
..., 60
.., 30
.., 30
. ., 107
.., 128
.., 102
.., 168
.., 168
.., 125
.., 25
.., 201
.., 164
.., 61
.., 116
.., 168
.., 129
.., 41
. ., 140
.., 74, 78
., 52
.., 63
.., 191
.., 82,
153
.., 38
.., 90
.., 80
.., 111
.., 167
.., 80
. ., 84
.., 43
.., 168
.., 96
.., 27
.., 182
.., 147, 148,
149
.., 134
., 120
.., 103
.., 28
.., 67
.., 54
.., 56
.., 41
.., 202
.., 82
..,, 153
.., 188
.., 42
. ., 107
.., 116
.., 125
., 169
.., 156
.., 180
.., 28
.., 36
.., 100
.., 157
.., 28, 29
.., 158
.., 29
.., 181
.., 173
.., 63

 -



6 8 2011 .
INTERNATIONAL STUDENT SCIENTIFIC CONFERENCE
THE CLINICAL AND THEORETICAL FEATURES
OF MODERN MEDICINE
6th 8th April 2011

Materials of the Conference

:
, ,

: , ,
, , ,

 28.03.2011 . 6084/8.
. . .
. . . 24,18. 200 . 398

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