Neurolipid Group
GRC – From Cell Metabolism to Metabolic Diseases
Neurolipid Group
GRC – Research Group in Regulation of Lipid Metabolism in obesity and diabetes
The Neurolipid Group studies lipid metabolism and signalling in the nervous system.
The brain is one of the tissues with significant lipid content. However, neurons do not usually use lipids as fuel for energy, which suggests that brain lipids have important structural and signalling functions. Our specific focus is the role that brain-specific carnitine palmitoyltransferase 1C (CPT1C) plays in neuronal lipid metabolism and its involvement in cognition, motor function and regulation of food intake and energy homeostasis.
Publications, Projects and Funding
Carnitine palmitoyltransferase 1C negatively regulates the endocannabinoid hydrolase ABHD6 in mice, depending on nutritional status.
Miralpeix C, Reguera AC, Fosch A, Casas M, Lillo J, Navarro G, Franco R, Casas J, Alexander SPH, Casals N, Rodríguez-Rodríguez R. Br J Pharmacol. 2021 Apr;178(7):1507-1523. doi: 10.1111/bph.15377. Epub 2021 Feb 12. PMID: 33444462
The return of malonyl-CoA to the brain: Cognition and other stories.
Fadó R, Rodríguez-Rodríguez R, Casals N. Prog Lipid Res. 2021 Jan;81:101071. doi: 10.1016/j.plipres.2020.101071. Epub 2020 Nov 10. PMID: 33186641
Publications, Projects and Funding
Carnitine palmitoyltransferase 1C negatively regulates the endocannabinoid hydrolase ABHD6 in mice, depending on nutritional status.
Miralpeix C, Reguera AC, Fosch A, Casas M, Lillo J, Navarro G, Franco R, Casas J, Alexander SPH, Casals N, Rodríguez-Rodríguez R. Br J Pharmacol. 2021 Apr;178(7):1507-1523. doi: 10.1111/bph.15377. Epub 2021 Feb 12. PMID: 33444462
The return of malonyl-CoA to the brain: Cognition and other stories.
Fadó R, Rodríguez-Rodríguez R, Casals N. Prog Lipid Res. 2021 Jan;81:101071. doi: 10.1016/j.plipres.2020.101071. Epub 2020 Nov 10. PMID: 33186641
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