Name	Known for
Yannick Bisson Detective William Murdoch Detective William Murdoch See fewer	Murdoch Mysteries (2008)
Helene Joy Dr. Julia Ogden (as Hélène Joy) Dr. Julia Ogden (as Hélène Joy) See fewer	Murdoch Mysteries (2008)
Thomas Craig Inspector Thomas Brackenreid Inspector Thomas Brackenreid See fewer	Murdoch Mysteries (2008)
Jonny Harris Constable George Crabtree Constable George Crabtree See fewer	Still Standing (2015)
Daniel Maslany Detective Llewellyn Watts Detective Llewellyn Watts See fewer	Impulse (2018)
Lachlan Murdoch Constable Henry Higgins Constable Henry Higgins See fewer	Cheaters (2002)
Arwen Humphreys Margaret Brackenreid Margaret Brackenreid See fewer	Murdoch Mysteries (2008)
Peter Stebbings James Pendrick James Pendrick See fewer	Defendor (2009)
Clare McConnell Effie Newsome Effie Newsome See fewer	Star Trek: Discovery (2017)
Jonathon Young Ernest Harding Ernest Harding See fewer	Sanctuary (2008)
Steffi DiDomenicantonio Melody Struthers Melody Struthers See fewer	Crawford (2018)
Janet Porter Donna Farrow Donna Farrow See fewer	Regression (I) (2015)
Christopher Hayes Garth Trent Garth Trent See fewer	Transplant (2020)
David Klein Sam Waters Sam Waters See fewer	Dream Scenario (2023)
David Rowan Vincent Cormac Vincent Cormac See fewer	Murdoch Mysteries (2008)