Name	Known for
Lauren Graham Lorelai Gilmore Lorelai Gilmore See fewer	Gilmore Girls (2000)
Alexis Bledel Rory Gilmore Rory Gilmore See fewer	The Sisterhood of the Traveling Pants (2005)
Melissa McCarthy Sookie St. James (credit only) Sookie St. James (credit only) See fewer	The Heat (I) (2013)
Keiko Agena Lane Kim Lane Kim See fewer	Prodigal Son (2019)
Yanic Truesdale Michel Gerard Michel Gerard See fewer	Étoile (2025)
Scott Patterson Luke Danes Luke Danes See fewer	Saw V (2008)
Milo Ventimiglia Jess Mariano Jess Mariano See fewer	Heroes (II) (2006)
Sean Gunn Kirk Gleason (credit only) Kirk Gleason (credit only) See fewer	Guardians of the Galaxy Vol. 2 (2017)
Kelly Bishop Emily Gilmore (credit only) Emily Gilmore (credit only) See fewer	Gilmore Girls (2000)
Edward Herrmann Richard Gilmore (credit only) Richard Gilmore (credit only) See fewer	Overboard (1987)
Emily Kuroda Mrs. Kim Mrs. Kim See fewer	RED (2010)
Adam Brody Dave Rygalski Dave Rygalski See fewer	The O.C. (2003)
Heidi Swedberg Debbie Fincher Debbie Fincher See fewer	Galaxy Quest (1999)
Jessica Kiper Shane Shane See fewer	Sex and Death 101 (2007)
Todd Lowe Zack Van Gerbig Zack Van Gerbig See fewer	True Blood (2008)
John Cabrera Brian Fuller Brian Fuller See fewer	H+ (2011)
Julie Wittner Jan Jan See fewer	Grey's Anatomy (2005)
Merry Simkins Lois Lois See fewer	Frailty (2001)
Damien Midkiff Boy Boy See fewer	Without a Trace (2002)
Michelle Moretti Girl Girl See fewer	Almost Famous (2000)
Riki Lindhome Girl Girl See fewer	The Last House on the Left (2009)
Rachel Marinacci Girl Girl See fewer	Road Trip (2000)
Jacqueline Campa Girl Girl See fewer	Gilmore Girls (2000)
Brenden Wing Townsperson Townsperson See fewer	Run This Town (2010)