In a study published in Nature, researchers report the successful in vitro reconstitution of meiotic DNA double-strand breaks (DSBs) formation.
Cell & Microbiology
Feb 21, 2025
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25
A team of stem cell scientists have successfully used embryonic stem cell engineering to create a bi-paternal mouse—a mouse with two male parents—that lived until adulthood.
Cell & Microbiology
Jan 28, 2025
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279
In a study of meiosis in budding yeast, a research team found that yeast senses temperature changes by increasing the level of DNA negative supercoils to increase crossovers and modulate chromosome organization during meiosis.
Cell & Microbiology
Aug 23, 2024
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13
Within every cell in our body, our DNA is tightly bundled with proteins to form structures known as chromosomes. The commonly known shape of a chromosome relates to an X-shaped appearance in many organisms. The formation ...
Plants & Animals
Feb 14, 2024
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9
In a new study published in the Proceedings of the National Academy of Sciences, University of Utah (the U) biologists have developed a method for illuminating the intricate interactions of the synaptonemal complex in the ...
Cell & Microbiology
Jan 3, 2024
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41
The gene editing technique CRISPR/Cas9 has allowed researchers to make precise and impactful changes to an organism's DNA to fix mutations that cause genetic disease. However, the CRISPR/Cas9 method can also result in unintended ...
Biotechnology
Sep 15, 2023
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58
Meiotic recombination assures genetic variation during breeding. During meiotic prophase I, chromosomes are organized in a loop-base array by a proteinaceous structure called meiotic chromosome axis, which is critical for ...
Plants & Animals
Mar 13, 2023
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7
Collaborating research groups in China have developed a novel technique, called DNA End tailing and sequencing (DEtail-seq), for meiotic DNA double-strand break (DSB) profiling.
Cell & Microbiology
Mar 2, 2023
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4
In most higher organisms, including humans, every cell carries two versions of each gene, which are referred to as alleles. Each parent passes on one allele to each offspring. As they are linked together on chromosomes, adjacent ...
Cell & Microbiology
Oct 24, 2022
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136
Unisexual reproduction lacks meiotic recombination, resulting in the accumulation of deleterious mutations and hindering the creation of genetic diversity. Thus, unisexual taxa are commonly considered an evolutionary dead ...
Evolution
Jul 11, 2022
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26
