Nucleome Informatics Pvt Ltd

"Join us at PAG2025! Nucleome Informatics, the proud sponsor of the event, is hosting a workshop on 'Genome Assembly of Plant, Animal, and Microbial Genomes' at 3:00 PM on March 18, 2025. We are excited to welcome Dr. Vinaya Kumar Katneni, Senior Scientist, ICAR-Central Institute of Brackishwater Aquaculture, who will share his insights and expertise. Looking forward to seeing you there!"

"Join us at PAG2025! Nucleome Informatics, the proud sponsor of the event, is hosting a workshop on 'Genome Assembly of Plant, Animal, and Microbial Genomes' at 3:00 PM on March 18, 2025. We are excited to welcome Dr. M.S. Shekhar, Principal Scientist & HoD, ICAR-Central Institute of Brackishwater Aquaculture, who will share his insights and expertise. Looking forward to seeing you there!"

"Join us at PAG2025! Nucleome Informatics, the proud sponsor of the event, is hosting a workshop on 'Genome Assembly of Plant, Animal, and Microbial Genomes' at 3:00 PM on March 18, 2025. We are excited to welcome Dr. Nagendra Kumar Singh, Indian Agricultural Scientist, National Professor, JC Bose National Fellow, who will share his insights and expertise. Looking forward to seeing you there!"

We are Hiring! Nucleome Informatics is hiring candidates for the Project Management and Operations department. Interested candidates can apply through the google form. https://lnkd.in/gCuhQNvd

We are Hiring! Nucleome Informatics is hiring candidates in the sales and marketing department. Interested candidates can apply through the google form. https://lnkd.in/g_tbX8_y

Exciting Collaboration in Genomics & Precision Medicine! We are thrilled to announce that Nucleome Informatics and Sri Ramachandra Institute of Higher Education and Research (SRIHER) have signed a Memorandum of Understanding (MoU) to advance cancer genomics, cardiology, and rare genetic disorders such as Inherited Retinal Diseases (IRD). This partnership focuses on: ✅ Joint research in oncology, cardiology, and rare diseases ✅ Clinical genetic testing to improve patient care ✅ Training programs to equip students with advanced genomics expertise ✅ Shared facilities to drive collaborative research ✅ Development of translational products for real-world clinical applications Nucleome has already developed DrSeqIRD, a specialized genetic test for Inherited Retinal Diseases, and with this collaboration, we will extend our innovations to oncology and cardiology—bringing cutting-edge genomics closer to clinical practice. The MoU was formalized at the “Genomics and Precision Medicine in Cancer” event, where our CEO, Mr. Dushyant Singh Baghel, was the Guest of Honour, and Dr. Kalpana Balakrishnan, Dean of SRIHER, chaired the session. The event saw active participation from clinicians, researchers, and medical students, reflecting the growing synergy between academia, hospitals, and the genomics industry. We look forward to transforming healthcare with precision genomics and translational research! #Genomics #PrecisionMedicine #CancerGenomics #Cardiology #RareDiseases #ClinicalGenetics #TranslationalResearch #NucleomeInformatics #SRIHER #HealthcareInnovation

Small RNA and miRNA Sequencing Services by Nucleome Informatics Unlock the Power of Small RNA and miRNA with Next-Generation Sequencing Small RNA and microRNA (miRNA) play crucial roles in gene regulation, disease pathways, and cellular functions. At Nucleome Informatics, we offer high-quality Small RNA and miRNA Sequencing services to help researchers gain deep insights into gene expression, RNA silencing, and regulatory mechanisms across various biological systems. Why Choose Nucleome for Small RNA and miRNA Sequencing • Comprehensive Coverage: Detect and profile known and novel small RNAs, including miRNAs, piRNAs, siRNAs, and other regulatory RNAs • High Sensitivity and Accuracy: Our advanced sequencing platforms provide single-nucleotide resolution and precise quantification of low-abundance RNAs • Expert Bioinformatics Support: Our analysis pipeline includes miRNA discovery, differential expression analysis, pathway enrichment, and target prediction for functional insights • Customized Data Analysis: Receive publication-ready reports with detailed annotations, expression profiles, and interactive visualizations • End-to-End Workflow: From RNA extraction to data interpretation, we provide a seamless and reliable sequencing experience Applications of Small RNA and miRNA Sequencing • Cancer Research: Study tumor-suppressor and oncogenic miRNAs for biomarker discovery • Neuroscience: Investigate miRNA roles in neurodegenerative diseases and brain function • Agrigenomics: Explore plant miRNAs involved in stress responses, growth, and development • Drug Development: Identify miRNA-based therapeutic targets and biomarkers • Infectious Diseases: Understand host-pathogen interactions and immune responses Our Small RNA and miRNA Sequencing Workflow 1. Sample Preparation: High-quality RNA extraction and QC assessment 2. Library Preparation: Small RNA-specific library construction with adapter ligation and size selection 3. Next-Generation Sequencing: Ultra-high-throughput sequencing on Illumina NovaSeq 6000 for deep coverage 4. Bioinformatics Analysis • miRNA identification and quantification • Novel small RNA discovery • Differential expression analysis • Functional annotation and pathway analysis 5. Comprehensive Reporting: Interactive data visualization, pathway enrichment, and insights for publication Technical Specifications • Platform: Illumina NovaSeq 6000 • Read Length: 50 base pairs single-end or paired-end sequencing • Recommended Depth: 10 to 20 million reads per sample • Data Output: FASTQ files, expression matrices, annotation reports, and pathway analysis Get Started with Nucleome’s Small RNA and miRNA Sequencing services: Whether you are exploring novel small RNAs, investigating disease biomarkers, or analyzing gene regulation, our expert team ensures high-quality, reproducible results tailored to your research needs. Contact us today to discuss your project and get a customized quote. www.nucleomeinfo.com

Nucleome Informatics Pvt Ltd had the honor of hosting a distinguished delegation from Murdoch University, Australia. The visiting team included Prof. Rajeev Varshney, FRS, a globally renowned expert in agricultural genomics, Prof. Peter Davies, Pro Vice-Chancellor, and Prof. Joy Gilesnan, Business Manager at the Food Futures Institute. The delegation was warmly welcomed by Mr. Dushyant Singh Baghel, CEO of Nucleome Informatics, who presented them with flowers and a traditional Indian silk shawl as a token of appreciation. During their visit, the guests toured Nucleome’s state-of-the-art genomics lab, where they interacted with the company’s team of scientists and gained insights into its advanced research capabilities. The discussions centered around Nucleome’s 12-year journey, its contributions to genomics and bioinformatics, and its impact on agriculture and healthcare. Both Nucleome Informatics and Murdoch University expressed keen interest in exploring collaborative research opportunities in genomics and bioinformatics, particularly in areas that can drive innovation in agriculture and healthcare. This partnership aims to leverage cutting-edge sequencing technologies and data-driven approaches to enhance global scientific advancements. Commenting on the visit, Mr. Dushyant Singh Baghel said: “We are delighted to host esteemed researchers from Murdoch University. This visit marks the beginning of a promising collaboration that can lead to transformative research in genomics and bioinformatics, benefitting both India and Australia.” With aligned visions in advancing precision agriculture, genetic research, and personalized healthcare, Nucleome Informatics and Murdoch University look forward to fostering a strong partnership that will contribute to the global scientific community.

Unveiling a Novel Multidrug-Resistant Fish Pathogen with PacBio HiFi Sequencing A groundbreaking study led by Dr. Basanta Kumar Das (CIFRI) has identified a novel pathogenic and multidrug-resistant strain of Kytococcus sedentarius in Labeo rohita (rohu fish). This bacterium, part of the Micrococcales order, has a genome size of 2.59 Mb, 71.7% GC content, and carries 2,173 antimicrobial resistance genes, raising serious concerns about antibiotic resistance in aquaculture. Using HiFi sequencing, the genome was assembled into a single contig, providing a complete, high-accuracy representation of the entire chromosome. This achievement underscores the power of long-read sequencing in generating high-quality pathogen genomes, essential for disease management and antimicrobial resistance studies. Nucleome Informatics Pvt Ltd is proud to support this cutting-edge research, which strengthens genomic surveillance, pathogen detection, and sustainable aquaculture practices. Read the full study: https://lnkd.in/gtknvV6B #HiFiSequencing #Genomics #WholeGenomeSequencing #AntimicrobialResistance #Aquaculture #Fisheries #Microbiology #PathogenGenomics #SustainableFarming #CIFRI

Day 2 at the Asian Fisheries and Aquaculture Forum: Advancing Genomics in Aquatic Sciences The second day at the Asian Fisheries and Aquaculture Forum has been incredibly engaging, with thought-provoking discussions on the role of genomics in sustainable aquaculture. As we continue our journey at Nucleome Informatics, it’s inspiring to see how genomic insights can drive better disease resistance, selective breeding, and overall productivity in fisheries. Our conversations with researchers, industry leaders, and policymakers reaffirm the growing need for Next-Generation Sequencing (NGS) in aquatic sciences—from understanding genetic diversity to optimizing breeding programs. The potential to enhance food security and sustainability through precision aquaculture is vast, and we are excited to contribute to this transformation. Looking forward to more insightful sessions and collaborations as we explore how genomics can redefine the future of fisheries and aquaculture. If you’re at the forum, stop by our booth for a discussion on how we can work together to bring genomic solutions to this industry! #AFAF2025 #GenomicsInAquaculture #SustainableFisheries #NucleomeInformatics