Yelland, T. et al. (2022) Stabilization of the RAS:PDE6D complex is a novel strategy to inhibit RAS signaling. Journal of Medicinal Chemistry, 65(3), pp. 1898-1914. (doi: 10.1021/acs.jmedchem.1c01265) (PMID:35104933) (PMCID:PMC8842248)
ElMaghloob, Yasmin, Sot, Begoña, McIlwraith, Michael J., Garcia, Esther, Yelland, Tamas and Ismail, Shehab ORCID: https://orcid.org/0000-0002-4150-1077
(2021)
ARL3 activation requires the co-GEF BART and effector-mediated turnover.
eLife, 10,
e64624.
(doi: 10.7554/elife.64624)
(PMID:33438581)
(PMCID:PMC7817177)
Stephen, Louise A., ElMaghloob, Yasmin, McIlwraith, Michael J., Yelland, Tamas, Castro Sanchez, Patricia, Roda-Navarro, Pedro and Ismail, Shehab ORCID: https://orcid.org/0000-0002-4150-1077
(2018)
The ciliary machinery is repurposed for T cell immune synapse trafficking of LCK.
Developmental Cell, 47(15),
122-132e4.
(doi: 10.1016/j.devcel.2018.08.012)
(PMID:30220567)
(PMCID:PMC6179904)
Alkanderi, S. et al. (2018) ARL3 mutations cause Joubert syndrome by disrupting ciliary protein composition. American Journal of Human Genetics, 103(4), pp. 612-620. (doi: 10.1016/j.ajhg.2018.08.015) (PMID:30269812) (PMCID:PMC6174286)
Stephen, Louise A., Elmaghloob, Yasmin and Ismail, Shehab ORCID: https://orcid.org/0000-0002-4150-1077
(2017)
Maintaining protein composition in cilia.
Biological Chemistry, 399(1),
pp. 1-11.
(doi: 10.1515/hsz-2017-0168)
(PMID:28850540)
Reid, S. E. et al. (2017) Tumor matrix stiffness promotes metastatic cancer cell interaction with the endothelium. EMBO Journal, 36(16), pp. 2373-2389. (doi: 10.15252/embj.201694912) (PMID:28694244) (PMCID:PMC5556271)