2020

Dietrichs, E. S., McGlynn, K., Allan, A., Connolly, A., Bishop, M., Burton, F., Kettlewell, S., Myles, R. , Tveita, T. and Smith, G. L. (2020) Moderate but not severe hypothermia causes pro-arrhythmic changes in cardiac electrophysiology. Cardiovascular Research, 116(13), pp. 2081-2090. (doi: 10.1093/cvr/cvz309) (PMID:32031595) (PMCID:PMC7584464)

2018

Colman, M. A., Saxena, P., Kettlewell, S. and Workman, A. J. (2018) Description of the human atrial action potential derived from a single, congruent data source: novel computational models for integrated experimental-numerical study of atrial arrhythmia mechanisms. Frontiers in Physiology, 9, 1211. (doi: 10.3389/fphys.2018.01211) (PMID:30245635) (PMCID:PMC6137999)

2017

Stevens, K., Denby, L., Patel, R. K., Mark, P. B. , Kettlewell, S., Smith, G. L. , Clancy, M. J., Delles, C. and Jardine, A. G. (2017) Deleterious effects of phosphate on vascular and endothelial function via disruption to the nitric oxide pathway. Nephrology Dialysis Transplantation, 32(10), pp. 1617-1627. (doi: 10.1093/ndt/gfw252) (PMID:27448672) (PMCID:PMC5837731)

2016

Høydal, M. A. et al. (2016) Exercise training reverses myocardial dysfunction induced by CaMKIIδC overexpression by restoring Ca2+-homeostasis. Journal of Applied Physiology, 121(1), pp. 212-220. (doi: 10.1152/japplphysiol.00188.2016) (PMID:27231311)

2015

Seidlmayer, L. K., Juettner, V. V., Kettlewell, S., Pavlov, E. V., Blatter, L. A. and Dedkova, E. N. (2015) Distinct mPTP activation mechanisms in ischaemia-reperfusion: contributions of Ca2+, ROS, pH, and inorganic polyphosphate. Cardiovascular Research, 106(2), pp. 237-248. (doi: 10.1093/cvr/cvv097) (PMID:25742913) (PMCID:PMC4415062)

2014

Boyman, L., Chikando, A. C., Williams, G. S.B., Khairallah, R. J., Kettlewell, S., Ward, C. W., Smith, G. L. , Kao, J. P.Y. and Lederer, W. J. (2014) Calcium movement in cardiac mitochondria. Biophysical Journal, 107(6), pp. 1289-1301. (doi: 10.1016/j.bpj.2014.07.045)

Haviland, S., Cleemann, L., Kettlewell, S., Smith, G. L. and Morad, M. (2014) Diversity of mitochondrial Ca²⁺ signaling in rat neonatal cardiomyocytes: evidence from a genetically directed Ca²⁺ probe mitycam-E31Q. Cell Calcium, 56(3), pp. 133-146. (doi: 10.1016/j.ceca.2014.06.001) (PMID:24994483)

O-Uchi, J. et al. (2014) Adrenergic signaling regulates mitochondrial Ca²⁺ uptake through Pyk2-dependent tyrosine phosphorylation of the mitochondrial Ca²⁺ uniporter. Antioxidants and Redox Signaling, 21(6), pp. 863-879. (doi: 10.1089/ars.2013.5394)

Liu, T., Takimoto, E., Dimaano, V. L., DeMazumder, D., Kettlewell, S., Smith, G. , Sidor, A., Abraham, T. P. and O'Rourke, B. (2014) Inhibiting mitochondrial Na+/Ca2+ exchange prevents sudden death in a guinea pig model of heart failure. Circulation Research, 115(1), pp. 44-54. (doi: 10.1161/CIRCRESAHA.115.303062) (PMID:24780171) (PMCID:PMC4219273)

Hohendanner, F., Walther, S., Maxwell, J. T., Kettlewell, S., Awad, S., Smith, G. , Lonchyna, V. A. and Blatter, L. A. (2014) Inositol-1,4,5-trisphosphate induced Ca2+release and excitation-contraction coupling in atrial myocytes from normal and failing hearts. Journal of Physiology, 593(6), pp. 1459-1477. (doi: 10.1113/jphysiol.2014.283226) (PMID:25416623)

2013

O-Uchi, J. et al. (2013) Overexpression of ryanodine receptor type 1 enhances mitochondrial fragmentation and Ca2+-induced ATP production in cardiac H9c2 myoblasts. American Journal of Physiology: Heart and Circulatory Physiology, 305(12), H1736-H1751. (doi: 10.1152/ajpheart.00094.2013)

Kettlewell, S., Burton, F. L., Smith, G. L. and Workman, A. J. (2013) Chronic myocardial infarction promotes atrial action potential alternans, afterdepolarisations and fibrillation. Cardiovascular Research, 99(1), pp. 215-224. (doi: 10.1093/cvr/cvt087) (PMID:23568957) (PMCID:PMC3687753)

Lu, X., Ginsburg, K.S., Kettlewell, S., Bossuyt, J., Smith, G.L. and Bers, D.M. (2013) Measuring local gradients of intramitochondrial [Ca²⁺] in cardiac myocytes during sarcoplasmic reticulum Ca²⁺ release. Circulation Research, 112(3), pp. 424-431. (doi: 10.1161/CIRCRESAHA.111.300501)

2011

Chikando, A.C., Kettlewell, S., Williams, G.S., Smith, G.L. and Lederer, W.J. (2011) Ca²⁺ dynamics in the mitochondria - state of the art. Journal of Molecular and Cellular Cardiology, 51(5), pp. 627-631. (doi: 10.1016/j.yjmcc.2011.08.003) (PMID:21864537) (PMCID:PMC3814218)

2009

Kettlewell, S., Seidler, T. and Smith, G.L. (2009) The effects of over-expression of the FK506-binding protein FKBP12.6 on K⁺ currents in adult rabbit ventricular myocytes. Pflügers Archiv - European Journal of Physiology, 458(4), pp. 653-660. (doi: 10.1007/s00424-009-0666-y)

Kettlewell, S., Cabrero, P., Nicklin, S.A. , Dow, J.A.T., Davies, S.A. and Smith, G.L. (2009) Changes of intra-mitochondrial Ca2+ in adult ventricular cardiomyocytes examined using a novel fluorescent Ca2+ indicator targeted to mitochondria. Journal of Molecular and Cellular Cardiology, 46(6), pp. 891-901. (doi: 10.1016/j.yjmcc.2009.02.016) (PMID:19249308)

2007

Schillinger, W. et al. (2007) Negative inotropy of the gastric proton pump inhibitor pantoprazole in myocardium from humans and rabbits - Evaluation of mechanisms. Circulation, 116(1), pp. 57-66. (doi: 10.1161/CIRCULATIONAHA.106.666008)

Seidler, T., Loughrey, C., Zibrova, D., Kettlewell, S., Teucher, N., Kogler, H., Hasenfuss, G. and Smith, G. (2007) Overexpression of FK-506-binding protein 12.0 modulates excitation-contraction coupling in adult rabbit ventricular cardiomyocytes. Circulation Research, 101(10), pp. 1020-1029. (doi: 10.1161/CIRCRESAHA.107.154609)

Walker, N., Burton, F., Kettlewell, S., Smith, G. and Cobbe, S. (2007) Mapping of epicardial activation in a rabbit model of chronic myocardial infarction: Response to atrial, endocardial, and epicardial pacing. Journal of Cardiovascular Electrophysiology, 18(8), pp. 862-868. (doi: 10.1111/j.1540-8167.2007.00858.x)

2006

Smith, G.L., Elliott, E.B., Kettlewell, S., Currie, S. and Quinn, F.R. (2006) Na+/Ca2+ Exchanger Expression and Function in a Rabbit Model of Myocardial Infarction. Journal of Cardiovascular Electrophysiology, 17(s1), S57-S63. (doi: 10.1111/j.1540-8167.2006.00384.x)

2005

Currie, S., Quinn, F., Sayeed, R., Duncan, A., Kettlewell, S. and Smith, G. (2005) Selective down-regulation of sub-endocardial ryanodine receptor expression in a rabbit model of left ventricular dysfunction. Journal of Molecular and Cellular Cardiology, 39(2), pp. 309-317. (doi: 10.1016/j.yjmcc.2005.04.005)

Kettlewell, S., Most, P., Currie, S., Koch, W. and Smith, G. (2005) S100A1 increases the gain of excitation-contraction coupling in isolated rabbit ventricular cardiomyocytes. Journal of Molecular and Cellular Cardiology, 39(6), pp. 900-910. (doi: 10.1016/j.yjmcc.2005.06.018)

Miller, S., Currie, S., Loughrey, C., Kettlewell, S., Seidler, T., Reynolds, D., Hasenfuss, G. and Smith, G. (2005) Effects of calsequestrin over-expression on excitation-contraction coupling in isolated rabbit cardiomyocytes. Cardiovascular Research, 67(4), pp. 667-677. (doi: 10.1016/j.cardiores.2005.04.023)

2004

Kettlewell, S., Walker, N., Cobbe, S., Burton, F. and Smith, G. (2004) The electrophysiological and mechanical effects of 2,3-butane-dione monoxime and cytochalasin-D in the Langendorff perfused rabbit heart. Experimental Physiology, 89(2), pp. 163-172. (doi: 10.1113/expphysiol.2003.026732)

2003

Seidler, T. et al. (2003) Effects of adenovirus-mediated sorcin overexpression on excitation-contraction coupling in isolated rabbit cardiomyocytes. Circulation Research, 93(2), pp. 132-139. (doi: 10.1161/01.RES.0000081596.90205.E2)