Hwej, Abdmajid, Al-Ferjani, Ali, Alshuweishi, Yazeed, Naji, Abdullah, Kennedy, Simon ORCID: https://orcid.org/0000-0003-0887-5840 and Salt, Ian
ORCID: https://orcid.org/0000-0003-0055-3724
(2024)
Lack of AMP-activated protein kinase-α1 reduces nitric oxide synthesis in thoracic aorta perivascular adipose tissue.
Vascular Pharmacology, 157,
107437.
(doi: 10.1016/j.vph.2024.107437)
(PMID:39433170)
Ramses, Rafic, Kennedy, Simon ORCID: https://orcid.org/0000-0003-0887-5840, Good, Richard, Oldroyd, Keith G. and Mcginty, Sean
ORCID: https://orcid.org/0000-0002-2428-2669
(2024)
Performance of drug-coated balloons in coronary and below-the-knee arteries: anatomical, physiological and pathological considerations.
Vascular Pharmacology, 155,
107366.
(doi: 10.1016/j.vph.2024.107366)
(PMID:38479462)
Hoare, Daniel, Kingsmore, David, Holsgrove, Michael, Russell, Ewan, Kirimi, Mahmut T., Czyzewski, Jakub, Mirzai, Nosrat, Kennedy, Simon ORCID: https://orcid.org/0000-0003-0887-5840, Neale, Steven L.
ORCID: https://orcid.org/0000-0002-4588-276X and Mercer, John R.
ORCID: https://orcid.org/0000-0002-3204-7511
(2024)
Realtime monitoring of thrombus formation in vivo using a self-reporting vascular access graft.
Communications Medicine, 4,
15.
(doi: 10.1038/s43856-024-00436-8)
(PMID:38316912)
(PMCID:PMC10844314)
Lyon, Mara, Fullerton, Josie L. ORCID: https://orcid.org/0000-0002-1967-9522, Kennedy, Simon
ORCID: https://orcid.org/0000-0003-0887-5840 and Work, Lorraine M.
ORCID: https://orcid.org/0000-0002-6462-4109
(2024)
Hypertension & dementia: pathophysiology & potential utility of antihypertensives in reducing disease burden.
Pharmacology and Therapeutics, 253,
108575.
(doi: 10.1016/j.pharmthera.2023.108575)
(PMID:38052309)
McQueen, Alistair, Escuer, Javier, Schmidt, André Fensterseifer, Aggarwal, Ankush ORCID: https://orcid.org/0000-0002-1755-8807, Kennedy, Simon
ORCID: https://orcid.org/0000-0003-0887-5840, McCormick, Christopher, Oldroyd, Keith and Mcginty, Sean
ORCID: https://orcid.org/0000-0002-2428-2669
(2022)
An intricate interplay between stent drug dose and release rate dictates arterial restenosis.
Journal of Controlled Release, 349,
pp. 992-1008.
(doi: 10.1016/j.jconrel.2022.07.037)
(PMID:35921913)
McQueen, Alistair, Escuer, Javier, Aggarwal, Ankush ORCID: https://orcid.org/0000-0002-1755-8807, Kennedy, Simon
ORCID: https://orcid.org/0000-0003-0887-5840, McCormick, Christopher, Oldroyd, Keith and Mcginty, Sean
ORCID: https://orcid.org/0000-0002-2428-2669
(2021)
Do we really understand how drug eluted from stents modulates arterial healing?
International Journal of Pharmaceutics, 601,
120575.
(doi: 10.1016/j.ijpharm.2021.120575)
(PMID:33845150)
Abdulqader, Abdulrazzaq and Kennedy, Simon ORCID: https://orcid.org/0000-0003-0887-5840
(2020)
The influence of perivascular adipose tissue on vascular function in a rabbit model.
Pharmacology and Pharmacy, 11,
pp. 331-349.
(doi: 10.4236/pp.2020.1112027)
McQueen, Alistair, Kennedy, Simon ORCID: https://orcid.org/0000-0003-0887-5840, McCormick, Chris, Aggarwal, Ankush
ORCID: https://orcid.org/0000-0002-1755-8807 and McGinty, Sean
ORCID: https://orcid.org/0000-0002-2428-2669
(2020)
Mathematical Modelling of the Effect of Drug on Smooth Muscle Cell Proliferation.
Scottish Cardiovascular Forum 2020, 23rd Annual Meeting, Glasgow, UK, 1 Feb 2020.
Alganga, Husam S F, Almabrouk, Tarek A.M. ORCID: https://orcid.org/0000-0002-2209-4218, Katwan, Omar J., Daly, Craig J.
ORCID: https://orcid.org/0000-0002-0410-7548, Pyne, Susan, Pyne, Nigel J. and Kennedy, Simon
ORCID: https://orcid.org/0000-0003-0887-5840
(2019)
Short periods of hypoxia upregulate sphingosine kinase 1 and increase vasodilation of arteries to Sphingosine 1-phosphate via S1P3.
Journal of Pharmacology and Experimental Therapeutics, 371(1),
pp. 63-74.
(doi: 10.1124/jpet.119.257931)
(PMID:31371480)
Katwan, Omar J., Alghamdi, Fatmah, Almabrouk, Tarek A. ORCID: https://orcid.org/0000-0002-2209-4218, Mancini, Sarah J., Kennedy, Simon
ORCID: https://orcid.org/0000-0003-0887-5840, Oakhill, Jonathan S., Scott, John W. and Salt, Ian P.
ORCID: https://orcid.org/0000-0003-0055-3724
(2019)
AMP-activated protein kinase complexes containing the β2 regulatory subunit are upregulated during and contribute to adipogenesis.
Biochemical Journal, 476(12),
pp. 1725-1740.
(doi: 10.1042/BCJ20180714)
(PMID:31189568)
(PMCID:PMC6595317)
McKittrick, Craig, McKee, Sean, Kennedy, Simon ORCID: https://orcid.org/0000-0003-0887-5840, Oldroyd, Keith, Wheel, Marcus, Pontrelli, Giuseppe, Dixon, Simon, Mcginty, Sean
ORCID: https://orcid.org/0000-0002-2428-2669 and McCormick, Christopher
(2019)
Combining mathematical modelling with in vitro experiments to predict in vivo drug-eluting stent performance.
Journal of Controlled Release, 303,
pp. 151-161.
(doi: 10.1016/j.jconrel.2019.03.012)
(PMID:30878363)
Ugusman, Azizah Binti, Riddell, Alex ORCID: https://orcid.org/0000-0003-4566-8680 and Kennedy, Simon
ORCID: https://orcid.org/0000-0003-0887-5840
(2019)
Effect of peroxynitrite (ONOO−) on the function of murine perivascular adipose tissue.
Pharmacology and Pharmacy, 10(4),
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(doi: 10.4236/pp.2019.104017)
Greig, F. H. et al. (2019) Requirement for sphingosine kinase 1 in mediating phase 1 of the hypotensive response to anandamide in the anaesthetised mouse. European Journal of Pharmacology, 842, pp. 1-9. (doi: 10.1016/j.ejphar.2018.10.027) (PMID:30359564) (PMCID:PMC6318480)
Kennedy, Simon ORCID: https://orcid.org/0000-0003-0887-5840 and Touyz, Rhian M.
ORCID: https://orcid.org/0000-0003-0670-0887
(2019)
Anatomy and pharmacology of vessels.
In: Touyz, Rhian M. and Delles, Christian (eds.)
Textbook of Vascular Medicine.
Springer: Cham, pp. 3-11.
ISBN 9783030164805
(doi: 10.1007/978-3-030-16481-2_1)
Mancini, Sarah J., Boyd, Daria, Katwan, Omar J., Strembitska, Anastasiya, Almabrouk, Tarek Ali, Kennedy, Simon ORCID: https://orcid.org/0000-0003-0887-5840, Palmer, Timothy M. and Salt, Ian P.
ORCID: https://orcid.org/0000-0003-0055-3724
(2018)
Canagliflozin inhibits interleukin-1β-stimulated cytokine and chemokine secretion in vascular endothelial cells by AMP-activated protein kinase-dependent and -independent mechanisms.
Scientific Reports, 8,
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(doi: 10.1038/s41598-018-23420-4)
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Almabrouk, Tarek A.M. ORCID: https://orcid.org/0000-0002-2209-4218, White, Anna D., Ugusman, Azizah B., Skiba, Dominik S., Katwan, Omar J., Alganga, Husam, Guzik, Tomasz J., Touyz, Rhian M.
ORCID: https://orcid.org/0000-0003-0670-0887, Salt, Ian P.
ORCID: https://orcid.org/0000-0003-0055-3724 and Kennedy, Simon
ORCID: https://orcid.org/0000-0003-0887-5840
(2018)
High fat diet attenuates the anticontractile activity of aortic PVAT via a mechanism involving AMPK and reduced adiponectin secretion.
Frontiers in Physiology, 9,
51.
(doi: 10.3389/fphys.2018.00051)
(PMID:29479319)
(PMCID:PMC5812172)
Almabrouk, Tarek Ali Mohamed ORCID: https://orcid.org/0000-0002-2209-4218, Ugusman, Azizah B., Katwan, Omar J., Salt, Ian P.
ORCID: https://orcid.org/0000-0003-0055-3724 and Kennedy, Simon
ORCID: https://orcid.org/0000-0003-0887-5840
(2017)
Deletion of AMPKα1 attenuates the anticontractile effect of perivascular adipose tissue (PVAT) and reduces adiponectin release.
British Journal of Pharmacology, 174(20),
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(doi: 10.1111/bph.13633)
(PMID:27668984)
Kennedy, Simon ORCID: https://orcid.org/0000-0003-0887-5840 and Salt, Ian P.
ORCID: https://orcid.org/0000-0003-0055-3724
(2017)
Molecular mechanisms regulating perivascular adipose tissue - potential pharmacological targets?
British Journal of Pharmacology, 174(20),
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(doi: 10.1111/bph.13969)
(PMID:28940457)
Wu, Junxi, Lawrence, Catherine, Wadsworth, Roger M. and Kennedy, Simon ORCID: https://orcid.org/0000-0003-0887-5840
(2017)
Perivascular mast cells promote neointimal elastin deposition and suppress chronic vein graft restenosis in hyperlipidaemic mice.
Vessel Plus, 2017(1),
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(doi: 10.20517/2574-1209.2017.15)
Greig, Fiona H., Kennedy, Simon ORCID: https://orcid.org/0000-0003-0887-5840, Gibson, George, Ramos, Joe W. and Nixon, Graeme F.
(2017)
PEA-15 (phosphoprotein enriched in astrocytes 15) is a protective mediator in the vasculature and is regulated during neointimal hyperplasia.
Journal of the American Heart Association, 6(9),
e006936.
(doi: 10.1161/JAHA.117.006936)
(PMID:28893763)
(PMCID:PMC5634313)
Ewart, Marie-Ann, Ugusman, Azizah, Vishwanath, Anisha, Almabrouk, Tarek A.M., Alganga, Husam S.F., Katwan, Omar J., Hubanova, Pavlina, Currie, Susan and Kennedy, Simon ORCID: https://orcid.org/0000-0003-0887-5840
(2017)
Changes in IP3 receptor expression and function in aortic smooth muscle of atherosclerotic mice.
Journal of Vascular Research, 54(2),
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(doi: 10.1159/000461581)
(PMID:28365690)
(PMCID:PMC5804831)
Houston, Stephanie A., Ugusman, Azizah, Gnanadesika, Sukanya and Kennedy, Simon ORCID: https://orcid.org/0000-0003-0887-5840
(2017)
An investigation of the antiplatelet effects of succinobucol (AGI-1067).
Platelets, 28(3),
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(doi: 10.1080/09537104.2016.1218456)
(PMID:27681689)
McGinty, Sean ORCID: https://orcid.org/0000-0002-2428-2669, McCormick, Christopher, McKittrick, Craig, Kennedy, Simon
ORCID: https://orcid.org/0000-0003-0887-5840, Oldroyd, Keith, Wheel, Marcus, Scullion, Brian, Pontrelli, Giuseppe and McKee, Sean
(2017)
Combining Mathematical Modelling with In-Vitro Experiments to Predict In-Vivo Drug-Eluting Stent Kinetics.
In: 5 th International Conference on Computational and Mathematical Biomedical Engineering (CMBE2017), Pittsburgh, PA, USA, 10-12 April 2017,
pp. 1011-1014.
ISBN 9780956291448
MacRitchie, Neil, Volpert, Giora, Al Washih, Mohammed, Watson, David G., Futerman, Anthony H., Kennedy, Simon ORCID: https://orcid.org/0000-0003-0887-5840, Pyne, Susan and Pyne, Nigel J.
(2016)
Effect of the sphingosine kinase 1 selective inhibitor, PF-543 on arterial and cardiac remodelling in a hypoxic model of pulmonary arterial hypertension.
Cellular Signalling, 28(8),
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(doi: 10.1016/j.cellsig.2016.03.014)
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(PMCID:PMC4913619)
McCormick, Christopher, Jones, Robert L., Wadsworth, Roger M., Mullen, Alexander B. and Kennedy, Simon ORCID: https://orcid.org/0000-0003-0887-5840
(2016)
A polymer coated cicaprost-eluting stent increases neointima formation and impairs vessel function in the rabbit iliac artery.
Pharmacology and Pharmacy, 7(6),
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McKittrick, C.M., Kennedy, S. ORCID: https://orcid.org/0000-0003-0887-5840, Oldroyd, K.G., Mcginty, S.
ORCID: https://orcid.org/0000-0002-2428-2669 and McCormick, C.
(2016)
Modelling the impact of atherosclerosis on drug release and distribution from coronary stents.
Annals of Biomedical Engineering, 44(2),
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(PMCID:PMC4764635)
Watt, Jonathan, Kennedy, Simon ORCID: https://orcid.org/0000-0003-0887-5840, Ahmed, Nadeem, Hayhurst, James, McClure, John D.
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ORCID: https://orcid.org/0000-0002-4547-8636, Wadsworth, Roger M. and Oldroyd, Keith G.
(2016)
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Open Heart, 3(1),
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(PMID:26848395)
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Greig, Fiona H., Ewart, Marie-Ann, McNaughton, Eilidh, Cooney, Josephine, Spickett, Corinne M. and Kennedy, Simon ORCID: https://orcid.org/0000-0003-0887-5840
(2015)
The hypotensive effect of acute and chronic AMP-activated protein kinase activation in normal and hyperlipidemic mice.
Vascular Pharmacology, 74,
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Wu, Junxi, Grassia, Gianluca, Cambrook, Helen, Ialenti, Armando, MacRitchie, Neil, Carberry, Jaclyn, Wadsworth, Roger M., Lawrence, Catherine, Kennedy, Simon ORCID: https://orcid.org/0000-0003-0887-5840 and Maffia, Pasquale
ORCID: https://orcid.org/0000-0003-3926-4225
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Perivascular mast cells regulate vein graft neointimal formation and remodeling.
PeerJ, 3,
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ORCID: https://orcid.org/0000-0003-2469-6316, Milligan, G.
ORCID: https://orcid.org/0000-0002-6946-3519 and Nicklin, S.A.
ORCID: https://orcid.org/0000-0002-9691-6210
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Atherosclerosis, 241(1),
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(doi: 10.1016/j.atherosclerosis.2015.04.158)
McDonald, R. A. et al. (2015) Reducing in-stent restenosis therapeutic manipulation of miRNA in vascular remodeling and inflammation. Journal of the American College of Cardiology, 65(21), pp. 2314-2327. (doi: 10.1016/j.jacc.2015.03.549) (PMID:26022821) (PMCID:PMC4444526)
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(2015)
Can Anisotropy Enhance the Spatial Uniformity of Drug Distribution in Biological Tissue?
In: 4th International Conference on Computational & Mathematical Biomedical Engineering, Paris, France, 29 June - 1 July 2015,
pp. 194-197.
ISBN 9780956291431
Farmer, David G.S., Ewart, Marie-Ann, Mair, Kirsty M. and Kennedy, Simon ORCID: https://orcid.org/0000-0003-0887-5840
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Soluble receptor for advanced glycation end products (sRAGE) attenuates haemodynamic changes to chronic hypoxia in the mouse.
Pulmonary Pharmacology and Therapeutics, 29(1),
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(2014)
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Atherosclerosis, 234(1),
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Almabrouk, T.A.M. ORCID: https://orcid.org/0000-0002-2209-4218, Ewart, M.-A., Salt, I.P.
ORCID: https://orcid.org/0000-0003-0055-3724 and Kennedy, S.
ORCID: https://orcid.org/0000-0003-0887-5840
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Perivascular fat, AMP-activated protein kinase and vascular diseases.
British Journal of Pharmacology, 171(3),
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Kennedy, S. ORCID: https://orcid.org/0000-0003-0887-5840, Wu, J., Wadsworth, R.M., Lawrence, C.E. and Maffia, P.
ORCID: https://orcid.org/0000-0003-3926-4225
(2013)
Mast cells and vascular diseases.
Pharmacology and Therapeutics, 138(1),
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(doi: 10.1016/j.pharmthera.2013.01.001)
Watt, J., Kennedy, S. ORCID: https://orcid.org/0000-0003-0887-5840, McCormick, C., Agbani, E.O., McPhaden, A., Mullen, A., Czudaj, P., Behnisch, B., Wadsworth, R.M. and Oldroyd, K.G.
(2013)
Succinobucol-eluting stents increase neointimal thickening and peri-strut inflammation in a porcine coronary model.
Catheterization and Cardiovascular Interventions, 81(4),
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(doi: 10.1002/ccd.24473)
Ewart, Marie-Ann and Kennedy, Simon ORCID: https://orcid.org/0000-0003-0887-5840
(2012)
Diabetic cardiovascular disease AMP-activated protein kinase (AMPK) as a therapeutic target.
Cardiovascular and Hematological Agents in Medicinal Chemistry, 10(3),
pp. 190-211.
(doi: 10.2174/187152512802651015)
Watt, Jonathan, Ewart, Marie-Ann, Greig, Fiona H., Oldroyd, Keith G., Wadsworth, Roger M. and Kennedy, Simon ORCID: https://orcid.org/0000-0003-0887-5840
(2012)
The effect of reactive oxygen species on whole blood aggregation and the endothelial cell-platelet interaction in patients with coronary heart disease.
Thrombosis Research, 130(2),
pp. 210-215.
(doi: 10.1016/j.thromres.2012.03.024)
Greig, Fiona H., Kennedy, Simon ORCID: https://orcid.org/0000-0003-0887-5840 and Spickett, Corinne M.
(2012)
Physiological effects of oxidized phospholipids and their cellular signaling mechanisms in inflammation.
Free Radical Biology and Medicine, 52(2),
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(doi: 10.1016/j.freeradbiomed.2011.10.481)
Watt, J., Ewart, M.-A., Greig, F.H., Oldroyd, K.G., Wadsworth, R.M. and Kennedy, S. ORCID: https://orcid.org/0000-0003-0887-5840
(2012)
The effect of reactive oxygen species on whole blood aggregation and the enothelial cell-platelet interaction in patients with coronary heart disease.
Thrombosis Research, 130(2),
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Ewart, Marie-Ann and Kennedy, Simon ORCID: https://orcid.org/0000-0003-0887-5840
(2011)
AMPK and vasculoprotection.
Pharmacology and Therapeutics, 131(2),
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Wu, J., Wadsworth, R.M. and Kennedy, S. ORCID: https://orcid.org/0000-0003-0887-5840
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Inhibition of inducible Nitric Oxide synthase promotes vein graft neoadventitial inflammation and remodelling.
Journal of Vascular Research, 48(2),
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Towards a self-reporting coronary artery stent—Measuring neointimal growth associated with in-stent restenosis using electrical impedance techniques.
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Activation of prostanoid EP receptors by prostacyclin analogues in rabbit iliac artery: Implications for anti-restenotic potential.
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Interaction between anandamide and sphingosine-1-phosphate in mediating vasorelaxation in rat coronary artery.
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The nitric oxide-donating pravastatin derivative, NCX 6550 [(1S-[1α(βS*,δS*), 2α ,6α,8 β-(R*),8aα]]-1,2,6,7,8,8a-hexahydro-β,δ,6-trihydroxy-2-methyl-8-(2-methyl-1-oxobutoxy)-1-naphtalene-heptanoic acid 4-(nitrooxy) butyl Ester)], Reduces Splenocyte Adhesion and Reactive Oxygen Species Generation in Normal and Atherosclerotic Mice.
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Inhibition of non-Ras protein farnesylation reduces in-stent restenosis.
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Multiphoton microscopy for 3-dimensional imaging of lymphocyte recruitment into apolipoprotein-E-deficient mouse carotid artery.
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Prostacyclin analogues: the next drug-eluting stent?
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PAR-2 mediates increased inflammatory cell adhesion and neointima formation following vascular injury in the mouse.
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Locally administered antiproliferative drugs inhibit hypercontractility to serotonin in balloon-injured pig coronary artery.
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A rapid, quantitative method for measuring leukocyte adhesion to normal and balloon-injured arteries in vitro.
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