RT Journal Article
SR 00
ID 10.1111/papt.12484
A1 McGuire, Nicola
A1 Gumley, Andrew
A1 Hasson-Ohayon, Ilanit
A1 Allan, Stephanie
A1 Aunjitsakul, Warut
A1 Aydin, Orkun
A1 Bo, Sune
A1 Bonfils, Kelsey
A1 Bröcker, Anna-Lena
A1 de Jong, Steven
A1 Dimaggio, Giancarlo
A1 Inchausti, Felix
A1 Jansen, Jens Einar
A1 Lecomte, Tania
A1 Luther, Lauren
A1 MacBeth, Angus
A1 Montag, Christiane
A1 Pedersen, Marlene Buch
A1 Pijnenborg, Gerdina Henrika Maria
A1 Popolo, Raffaele
A1 Schwannauer, Matthias
A1 Trauelsen, Anne-Marie
A1 Donkersgoed, Rozanne van
A1 Wu, Weiming
A1 Lysaker, Paul
A1 McLeod, Hamish
T1 Investigating the relationship between negative symptoms and metacognitive functioning in psychosis: an individual participant data meta-analysis
JF Psychology and Psychotherapy: Theory, Research and Practice
YR 2023
FD 2023-12
VO 96
IS 4
SP 918
OP 933
AB Purpose:  Negative symptoms are a persistent, yet under-explored problem in psychosis. Disturbances in metacognition are a potential causal factor in negative symptom development and maintenance. This meta-analysis uses individual participant data (IPD) from existing research to assess the relationship between negative symptoms and metacognition treated as summed scores and domains.    Methods:  Data sets containing individuals with negative symptoms and metacognition data, aged 16+ with psychosis, were identified according to pre-specific parameters. IPD integrity and completeness were checked and data were synthesized in two-stage meta-analyses of each negative symptoms cluster compared with metacognition in seemingly unrelated regression using restricted maximum likelihood estimation. Planned and exploratory sensitivity analyses were also conducted.    Results:  Thirty-three eligible data sets were identified with 21 with sufficient similarity and availability to be included in meta-analyses, corresponding to 1301 participants. The strongest relationships observed were between summed scores of negative symptoms and metacognition. Metacognitive domains of self-reflectivity and understanding others' minds, and expressive negative symptoms emerged as significant in some meta-analyses. The uncertainty of several effect estimates increased significantly when controlling for covariates.    Conclusions:  This robust meta-analysis highlights the impact of using summed versus domain-specific scores of metacognition and negative symptoms, and relationships are not as clear-cut as once believed. Findings support arguments for further differentiation of negative symptom profiles and continued granular exploration of the relationship between metacognition and negative symptoms.
PB Wiley
SN 1476-0835
LK https://eprints.gla.ac.uk/302764/