TY  - JOUR
N1  - MT-R is part funded by Chest Heart and Stroke Scotland; this
work is part of the APPLE program of work funded by the Stroke
Association and Chief Scientist Office Scotland. TQ is supported
by a Stroke Association, Chief Scientist Office Senior Lectureship.
ID  - enlighten160129
UR  - https://eprints.gla.ac.uk/160129/
A1  - Taylor-Rowan, Martin
A1  - Wilson, Alastair
A1  - Dawson, Jesse
A1  - Quinn, Terence J.
Y1  - 2018/03/26/
N2  - A measure of treatment effect is needed to assess the utility of any novel intervention in acute stroke. For a potentially disabling condition such as stroke, outcomes of interest should include some measure of functional recovery. There are many functional outcome assessments that can be used after stroke. In this narrative review, we discuss exemplars of assessments that describe impairment, activity, participation, and quality of life. We will consider the psychometric properties of assessment scales in the context of stroke trials, focusing on validity, reliability, responsiveness, and feasibility. We will consider approaches to the analysis of functional outcome measures, including novel statistical approaches. Finally, we will discuss how advances in audiovisual and information technology could further improve outcome assessment in trials.
PB  - Frontiers Media
JF  - Frontiers in Neurology
VL  - 9
SN  - 1664-2295
TI  - Functional assessment for acute stroke trials: properties, analysis, and application
AV  - public
ER  -