eprintid: 109839 rev_number: 24 eprint_status: archive userid: 29122 dir: disk0/00/10/98/39 datestamp: 2015-09-08 11:56:25 lastmod: 2022-02-21 22:02:39 status_changed: 2015-09-08 11:56:25 type: article metadata_visibility: show creators_name: Morrison, A.P. creators_name: Shryane, N. creators_name: Fowler, D. creators_name: Birchwood, M. creators_name: Gumley, A.I. creators_name: Taylor, H.E. creators_name: French, P. creators_name: Stewart, S.L.K. creators_name: Jones, P.B. creators_name: Lewis, S.W. creators_name: Bentall, R.P. creators_orcid: 0000-0002-8888-938X title: Negative cognition, affect, metacognition and dimensions of paranoia in people at ultra-high risk of psychosis: a multi-level modelling analysis ispublished: pub divisions: 25602000 abstract: Background: Paranoia is one of the commonest symptoms of psychosis but has rarely been studied in a population at risk of developing psychosis. Based on existing theoretical models, including the proposed distinction between ‘poor me’ and ‘bad me’ paranoia, we aimed to test specific predictions about associations between negative cognition, metacognitive beliefs and negative emotions and paranoid ideation and the belief that persecution is deserved (deservedness). Method: We used data from 117 participants from the Early Detection and Intervention Evaluation for people at risk of psychosis (EDIE-2) trial of cognitive–behaviour therapy, comparing them with samples of psychiatric in-patients and healthy students from a previous study. Multi-level modelling was utilized to examine predictors of both paranoia and deservedness, with post-hoc planned comparisons conducted to test whether person-level predictor variables were associated differentially with paranoia or with deservedness. Results: Our sample of at-risk mental state participants was not as paranoid, but reported higher levels of ‘bad-me’ deservedness, compared with psychiatric in-patients. We found several predictors of paranoia and deservedness. Negative beliefs about self were related to deservedness but not paranoia, whereas negative beliefs about others were positively related to paranoia but negatively with deservedness. Both depression and negative metacognitive beliefs about paranoid thinking were specifically related to paranoia but not deservedness. Conclusions: This study provides evidence for the role of negative cognition, metacognition and negative affect in the development of paranoid beliefs, which has implications for psychological interventions and our understanding of psychosis. date: 2015-09 date_type: published publisher: Cambridge University Press id_number: 10.1017/s0033291715000689 copyright_holders: Copyright © 2015 Cambridge University Press prior: First published in Psychological Medicine 45(12):2675-2684 repro: Reproduced in accordance with the copyright policy of the publisher. uniqueid: glaseprints:2015-109839 published_online: 2015-07-13 issn_online: 1469-8978 funding_project_code: 42376 funding_award_no: 1 funding_project_name: Early detection and psychological intervention for individuals at high risk of psychosis funding_investigator_name: Andrew Gumley funding_funder_name: Medical Research Council (MRC) funding_funder_code: G0500264/73571 funding_investigator_dept: IHW - MENTAL HEALTH & WELLBEING pubmed_id: 26165380 euro_pubmed_id: 26165380 full_text_status: public publication: Psychological Medicine volume: 45 number: 12 pagerange: 2675-2684 refereed: TRUE issn: 0033-2917 hoa_compliant: 319 hoa_date_acc: 2015-03-17 hoa_date_pub: 2015-09 hoa_date_fcd: 2015-12-15 hoa_date_foa: 2016-02-11 hoa_version_fcd: AM hoa_exclude: FALSE hoa_gold: FALSE rioxx2_dateAccepted_input: 2015-03-17 citation: Morrison, A.P. et al. (2015) Negative cognition, affect, metacognition and dimensions of paranoia in people at ultra-high risk of psychosis: a multi-level modelling analysis. Psychological Medicine , 45(12), pp. 2675-2684. (doi: 10.1017/s0033291715000689 ) (PMID:26165380) document_url: https://eprints.gla.ac.uk/109839/7/109839.pdf