Diverse Metastable Structures Formed by Small Oligomers of α-Synuclein Probed by Force Spectroscopy
Figure 3
(A, B) Representative FECs of a dimer show unfolding of stable structures with a wide range of sizes and unfolding forces. WLC fits to determine contour length changes are displayed as dashed lines (grey: folded states, red: unfolded state). Inset: the dimer contains two monomers connected by short, flexible peptides linkers. (C) Histogram of ΔLc for all identifiable transitions in dimer FECs.
doi: https://doi.org/10.1371/journal.pone.0086495.g003