Histological Assessment of PAXgene Tissue Fixation and Stabilization Reagents
Figure 5
In figure 5a the most common prognostic (ER and PR) and pharmaco diagnostic markers (Her2Neu and EGFR) are shown. ER, PR are stained in serial sections of the same breast tumor sample. Her2Neu IHC as well as CISH was performed on a breast cancer sample with Her2Neu over expression and gene amplification. EGFR is stained in skin samples. The left column shows PAXgene-fixed sections, the column on the right shows formalin-fixed sections. (ER, PR, Her2Neu 400×; EGFR 100× original magnification). In figure 5b the most common tumor differentiation markers are shown. CD3 is stained in lymph node. S100, Pan-Keratin and vimentine are stained in colon tissue. The left column shows PAXgene-fixed sections, the column on the right show formalin-fixed sections. (200× original magnification).
doi: https://doi.org/10.1371/journal.pone.0027704.g005